Congrats to our talented postdoc @amirbitran.bsky.social for his first preprint in the lab, a collaboration with the Bustamante lab, studying time-resolved protein folding during translation elongation with HDX-MS! Check out the attached manuscript and tutorial for more:

🚨 New in @natmicrobiol.nature.com! We reveal how the antibiotic target PBP1b fortifies the E.coli division site against osmotic rupture. Proud this was completed in our independent labs @dmf-unil.bsky.social, with @avettiger.bsky.social. Congratulations to all authors! 🦠❄️🔬 #teamtomo bit.ly/3SCbOg1 👇

Congrats to the 2026 Zara Weinberg Leading Edge Fellows - we're especially delighted to see JCC Fellows Dr. Airi Yoshimoto and Dr. Meenakshi Asokan in this cohort! @airiyoshimoto.bsky.social @meenakshiasokan.bsky.social

Congratulations, Steve! Well deserved 🎊🎉🎊

Thrilled to share this #lipidtime mechanism story in @jcb.org where, led by Shiying Huang and in collaboration with Tamas Balla’s lab, we uncover plasticity in phospholipid metabolism to preserve plasma membrane identity and integrity in the face of disease-relevant perturbations!

What if learning structural biology felt more like playing a game? Meowtabolism aims to make the structural sciences more interactive, accessible & fun. If you have educational applications let Muyuan (or me) know. store.steampowered.com/app/4045010/... #CryoEM #ScienceOutreach #STEMEducation

Fun news! I was named one of the inaugural #SciAmYoungAmericanScientists! Thank you to whoever nominated me - I’m excited for the research ahead in @thegardinerlab.bsky.social and working with my stellar students!

We are thrilled to announce the 2026 Zara Weinberg Leading Edge Fellows! 40 remarkable postdocs pursuing transformative research in biological/biomedical sciences. This is the 7th Leading Edge cohort and we are so excited to welcome them! www.leadingedgesymposium.org/fellows/

It's Leading Edge Fellow day!!! This day fills me with joy and inspiration. This cohort holds a special place in my heart because it is named for Zara Weinberg, a beloved Leading Edge Fellow who was a visionary scientist and fierce advocate for building a better scientific ecosystem

If you are an ASCB member, please consider nominating a junior colleague with a strong, promising research program who is already demonstrating leadership in their field, department, and the broader community for the WICB Junior Award for Excellence in Research. www.ascb.org/award/women-...

It was an honor to host @yiweichang.bsky.social from @upenn.edu @isbupenn.bsky.social for a seminar at @ohsunews.bsky.social's Department of Chemical Physiology and Biochemistry!

Very excited about our new work highlighting the role of lipids in mediating multi-channel assemblies of Cx-46/50!

Dual-channel Cx46/50 gap junction assemblies in a shared lipid-nanodisc = lipid-mediated packing and a lipid site near the NT gating region that is absent from single channels. Plus a 1.8 Å open-state single-channel benchmark! #cryo-EM 🍩’s #NIH-funded-research www.biorxiv.org/content/10.6...

CS tools is very handy! Just added another couple of CS tools scripts to my github - one for making adjustable templates for picking membrane proteins in nanodiscs & micelles: github.com/olibclarke/c... (cont. next post:)

🚨first Bartman lab preprint! it's an LC-MS method to measure "total Coenzyme A" (sum of all acyl-CoAs). this will let us study coA synthesis flux using heavy-isotope tracing! huge congrats to first author Amelia Taylor and star coauthor @mzspectrum.bsky.social ! www.biorxiv.org/content/10.6...

Delighted to see our paper featured on the cover of JNeurosci. this week. While this study focused on the role of SCD1 in developmental myelination, the data also pointed us toward potentially broader functions for SCD2 that we are now actively pursuing #sfnjournals www.jneurosci.org/content/46/1...

Thank you OHSU @ohsunews.bsky.social for the research week profile! Honored to share my lab's work on peroxisomes with the community. 🔬 www.mguptalab.com news.ohsu.edu/2026/05/04/s...

The 2027 Biophysical Society #CryoEM Subgroup welcomes nominations for the June Almeida Award for Mid/Senior-Career Women in CryoEM. The nomination deadline is November 13, 2026, but feel free to submit nominations anytime. Eligibility & requirements found here: www.biophysics.org/Awards-Fundi...

Excited to share a new collaborative paper with Lena Koslover's team, fueled by @chanzuckerberg.bsky.social Metabolism Across Scales Program 🧪 1/ www.pnas.org/doi/10.1073/...

It’s done!! Molecular architecture of the ciliary base in mammalian multiciliated cells! A study 13 years in the making 👴, thanks to collab with @stearnslab.bsky.social + @centriolelab.bsky.social & visionary work by @computingcaitie.bsky.social, who integrated native #cryoET with #XLMS & #UExM 🧪🧶🧬🔬

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density. Lipid-CLEM, now out in @natcellbio.nature.com brought to you by @mathilda95.bsky.social changes that: www.nature.com/articles/s41...

Great day at NYSBC, thanks for having me! 😊 If anyone wants to try out the tutorial, here it is: www.dropbox.com/scl/fi/054cm... There are linked videos for each step in the PDF, or I have also prepared the whole thing as a .PPT with embedded videos (2.7GB): www.dropbox.com/scl/fi/jnl9h...

I've been leading a big project at Methods in Enzymology over the past year or so: editing three back-to-back-to-back volumes of articles describing the latest advances in methods for studying lipids and membranes — thank you to the 50 #lipidtime luminaries who contributed the 51 chapters! Details 👇

1st McKinley Lab grad student’s 1st preprint! @claireang.bsky.social studied how the uterus safely excises massive amounts of tissue during menstruation and pregnancy. Come for her GORGEOUS images, stay for her incredible discoveries. www.biorxiv.org/content/10.6... w/ @akelleher1017.bsky.social

I am so excited to co-organize the scientific program for ASBMB 2027 together with Amy Palmer @amypalmerzinc.bsky.social! Please join us in beautiful Boston April 3-6, 2027. Interested in organizing an ASBMB mini-symposia or workshop? Submit your proposals here!: www.asbmb.org/annual-meeti...

So much fun to see all the Leading Edge members at ASBMB. an honor to know such amazing women in science! @phosphotig.bsky.social @meghnag27.bsky.social @ceej64.bsky.social

Join us for a great session @asbmb.bsky.social annual meeting tomorrow. Our session starts at 9:30 am!

On my way to DC and looking forward to this exciting mini-symposium! #ASBMB26

Glad to see this news story highlighting our recent lipid interactome database, a resource we hope will help the broader scientific community. @ohsummi.bsky.social @ohsunews.bsky.social news.ohsu.edu/2026/02/25/n...

🎗️ February marked Gallbladder & Bile Duct Cancer Awareness Month, highlighting #Cholangiocarcinoma. Often diagnosed at advanced stages, with limited early detection. #RareCancers remain part of the broader #Oncology landscape. 🔗 https://bit.ly/3KQY0tS #RareDiseaseDay #RareDisease

💚 February is Cholangiocarcinoma Awareness Month! 💚 All month long, we’re coming together to raise awareness, share stories from patients and caregivers, and shine a light on this cancer. This is a time to learn, connect, and amplify voices that deserve to be heard. curecca.link/awarenessmonth26.

Sooo happy to share our new paper in @nature.com “CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.” A terrific collaboration with @arrudalab.bsky.social, led by co–first authors Alyssa Mathiowetz and Emily Maymand. www.nature.com/articles/s41...

Our paper on The Lipid Interactome is now published, and the database is open: lipidinteractome.org @ohsummi.bsky.social @ohsunews.bsky.social @nadlerlab.bsky.social @jeremybaskin.bsky.social Please RT to spread the word. doi.org/10.1093/bioi...

Most people have never heard of cholangiocarcinoma, yet it’s the 2nd most common liver cancer. Awareness isn’t just important, it’s life-changing. Knowledge leads to early detection, research, and hope. Let’s make CCA known. Join us for #WorldCCADay tomorrow, February 19. 🌍

💚 Save the Date: World Cholangiocarcinoma Day — February 19, 2026 💚 February 19 is a global moment to raise awareness of bile duct cancer and stand with patients, caregivers, and families. This Awareness Month, explore ways to get involved and inspire action: https://curecca.link/awarenessmonth26.

@asbmb.bsky.social www.asbmb.org/meetings-eve...

Big career update:  I’m honored and humbled to serve as Chair of the Department of Molecular Microbiology & Immunology at Oregon Health & Science University (OHSU). Looking forward to what we’ll build together! @ohsummi.bsky.social @ohsunews.bsky.social

We are organizing a mini-symposium on "Membrane and Organelle Dynamics" at ASBMB 2026! #ASBMB @asbmb.bsky.social @aydinlab.bsky.social and I have put together a fantastic lineup of speakers for Day 1 morning. Come learn about some cutting-edge research in the field.

I’m so excited to share that I’ve accepted an assistant professor position at the University of Colorado Anschutz, BMG department and Barbara Davis Diabetes center! I’m so grateful to many who have helped me get here, especially mentors at Joslin, @hmsbpa.bsky.social @leadingedgeprogram.bsky.social

I am very excited to share the first Accorsi lab publication: a collection of detailed protocols to maintain an apple snail 🐌 colony and generate stable mutant lines. The video is coming soon @ JoVE! We hope this will be a valuable resource for the community. app.jove.com/t/69267/the-...

Molecular mechanism of substrate transport by human peroxisomal ABCD3 pubmed.ncbi.nlm.nih.gov/41428872/ #cryoem

Exciting holiday present for the Gupta lab! 🎉 🎊 Our paper "Molecular mechanism of substrate transport by human peroxisomal ABCD3" is now published in @pnas.org !! 🎉 🎊 lnkd.in/gPaFdEMn. @ohsunews.bsky.social #OHSU #mguptalab #NIHfunded www.mguptalab.com

Great start to #CellBio2025 in Philadelphia with "The Peroxisome Renaissance: From Molecular Mechanisms to Cellular Functions" session organized by @fredmast.bsky.social. Really enjoyed speaking alongside Bonnie Bartel, Michael Skowyra, Jie Sun, Francesca Di Cara, PhD, and Peter Kim. 🙌

New preprint out! We show that PROTAC-induced ubiquitination can bypass canonical ERAD to degrade ER membrane proteins. Wonderful collaboration w/ @dannomura.bsky.social and huge credit to grad student superstar Sydney Tomlinson! www.biorxiv.org/content/10.1...

CryoET of microbes inside an animal organ? Yes it’s possible! Check out our new preprint showing how we did it! What an amazing collaboration with amazing scientists who made this possible!

Prohibitins aren’t hanging out just anywhere in the membrane — they prefer the 💁‍♀️💎✨VIP section💅🪩🥂 Lab all-star @mmedina300kv.bsky.social maps these microdomains using cryo-ET + surface morphometrics. s/o to #teamtomo #cryoET co-authors @hamid13r.bsky.social @attychang.bsky.social @baradlab.com

Excited to share the peer-reviewed version of our work, now online in @embojournal.org! Big thanks to our reviewers and @hvodermaier.bsky.social for facilitating this process. Looking forward to continuing this fun collaboration with @michaelnadbio.bsky.social! www.embopress.org/doi/full/10....

The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor. The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2. www.leadingedgesymposium.org/apply/

Zara Weinberg passed away earlier this week. She joined my lab earlier this year when her postdoc lab formally closed. She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.