1/6 Extremely happy to share my PhD work is out on bioRxiv! We discovered that microtubules deform mitotic centrosomes. When we removed them, the SPD-5 scaffold became denser but didn't lose material. This suggests it's an elastically deformable solid! This only happens in mitosis.

[We are Hiring!] The Weiss Lab at Albert Einstein College of Medicine (NY) is hiring a Postdoc Scientist to explore the Toxoplasma gondii cyst wall using XL-MS, Split TurboID, & U-ExM. This project aims to unlock new strategies for treating toxoplasmosis. DM for more info!

Lately I've been only posting images of really interesting protist here, but something that many don't know is that most of my time i'm expanding 'boring' mammalian cells and that I love human centrioles. Don't tell me that they are not beautiful😍👁️ #FluorescenceFriday #CellBiology #Cytoskeleton

Years ago we discovered that missense mutations in homomeric proteins often induces their supramolecular assembly, as in the 📽️👇 - Are such aberrant assemblies of *folded* proteins toxic? Surprisingly, NO. Cells are amazingly robust systems! Paper now online @molsystbiol.org doi.org/10.1038/s443...

We’re looking for a #postdoc to join Lori Passmore’s group, within a programme aimed at understanding addition of mRNA poly(A) tails More info: www.nature.com/naturecareer... Closes 06 OCT #ScienceJobs #PostdocJobs

Be our new colleague! 🎉 The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor. 👉 More details here: lnkd.in/e8Z9eAm4 👉 Our department: mocel.unige.ch Please feel free to share this opportunity with your network.

Early-career researchers: want to run your own lab? 🌟Max Planck Research Groups offer 6+ years, up to €2.7M in funding, open-topic freedom, team support & tenure-track opportunities. Intrigued? 😃Apply by Oct 14, 2025! www.mpg.de/max-planck-r...

@embl.org Heidelberg is looking for a new Head of Scientific Instrumentation! This is an exciting opportunity at the interface between scientific research and technology development, overseeing our mechanical and electronic workshops! embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia: Current Biology www.cell.com/current-biol...

🧬 New tool for U-ExM! HAK-Actin is now available from Spirochrome → a reliable probe to label actin filaments in expansion microscopy. Check it out at Spirochrome! #UExM #Actin #Cytoskeleton #SuperResolution

Discover HAK-actin™: A New Tool To Visualize The Actin Cytoskeleton by Expansion Microscopy • Stronger signal via post-expansion labeling • Broad cell lines & species compatibility • Endogenous actin labeling • Can be multiplexed with other targets spirochrome.com/product/hak-...

The Dunn School PhD programme is live! 🎉 Two projects in our labs: 1) How the motor protein giant dynein-2 works 2) How signalling-essential membrane proteins get into cilia Cryo-EM/ET, single mol & live-cell fluor microscopy, CRISPR-based genetic tools & more! www.path.ox.ac.uk/study-with-u...

🏅Congratulations to Emeritus Prof. Ueli #Schibler for receiving the #Kappers Medal from the #EBRS: the Society’s highest honor, awarded for outstanding contributions to biological rhythms research @sciencesunige.bsky.social @mocel.bsky.social #UNIGE ebrs-online.org/index.php/abou

@ascbiology.bsky.social Abstract submissions are open! Submit an abstract to the ‘Emerging concepts in centriole and centrosome assembly and function’ minisym. PRIZES for trainee talks & posters plus a mixer thanks to generous sponsors @jcellsci.bsky.social @dshb-antibodies.bsky.social & Nikon

A new #UExM probe for #Actin! Fun times thinking/developing/testing with @centriolelab.bsky.social & @lreymond.bsky.social ! Congrats to all ! If interested in #UExM, or #HAK-Actin, feel free to reach out ! Soon available at @spirochrome.com #Expansion #Microscopy #ProtistsOnSky

New preprint online! So much fun working on this project, thank you @centriolelab.bsky.social and @dudinlab.bsky.social for embarking me on this one! Hopefully HAK-actin will become your best companion for actin staining U-ExM expanded samples.

Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1... Soon at @spirochrome.com Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social

🧪 The University of Basel is setting up a new endowed professorship in #ClimateBiophysics at the @biozentrum.unibas.ch, funded by the Georg H. Endress Foundation. This new professorship strengthens climate research @unibas.ch. www.biozentrum.unibas.ch/news/detail/...

Congratulations @elevylab.bsky.social and collaborators for your latest publication in Cell 👏 and welcome to BlueSky 🦋@mocel.bsky.social‬ @sciencesunige.bsky.social

🔎New preprint! We reveal a physiological role for tubulin autoregulation, fine-tuning microtubule dynamics and preserving 3D cellular architecture. Big thanks to @ivanagasic.bsky.social and team! Link below for all #cytoskeleton & #spheroid enthusiasts👇(1/5) www.biorxiv.org/content/10.1...

The Dunn School is a really great environment for taking up a Career Development Fellowship, and we are looking for candidates! Please spread the word.

Thrilled to see our study on how kinesin-2 motors are switched on and off published in @natsmb.nature.com ⚛️ ➡️ www.nature.com/articles/s41... Congrats to all authors from me and Anthony 🎉 @dunnschool.bsky.social Check out this animation made by talented PhD student @matthew-batisio.bsky.social 😆

New preprint: In situ Architecture of #Plasmodesmata. Using #cryoET, #AlphaFold & proteomics, we uncover the native organization of plant intercellular nanopores. 🔗 doi.org/10.1101/2025... 🧪🧵1/n #teamtomo #PlantScience #Physcomitrium #Arabidopsis #cryoEM

📢 Excited to share our new study in Nature Communications! We show that the A-C linker safeguards centriole architecture & controls duplication. A big congratulations to Lorène for this beautiful discovery, which represents 4 years of her thesis work. www.nature.com/articles/s41...

The nucleus is fantastic, but can it beat #cilia and #flagella 😉 here stained for tubulin (magenta) with an intraflagellar transport train (green) after #expansion microscopy and #STED or shown by classic TEM. JCS @jcellsci.bsky.social found the solution and is featuring both! 😍

🚨 New EMBO Practical Course! Ultrastructure Expansion Microscopy: From Cells to Tissue 🔬 📅 20–24 Apr 2026 | 📍 EMBL Heidelberg Co-organised with @banterlegroup.bsky.social @gautamdey.bsky.social 💡 Register your interest to get notified when registration opens: 🔗 www.embl.org/about/info/c...

Finally out! Mass spec analysis of #trypanosome flagellar tubulins reveals some surprises including a new #glutamylation site on beta-tubulin! Many thanks to the teams of Julia Chamot-Rooke and Mariette Matondo! pubs.acs.org/doi/10.1021/...

After the success of our 2023 Imaging Cell Dynamics conference, we’ll be hosting a second #JCSImaging meeting in 2026, organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social‬, @drmichaelway.bsky.social‬ & Giulia Zanetti. To register your interest: www.biologists.com/meetings/jcs...

Performing cryoET on microtubules stabilised on grids in this way, we found that stabilised microtubule ends carry short and clustered protofilaments - properties that we previously described as characteristic for growing microtubules, despite the fact that microtubules were actually shortening(3/7)

Exciting and rare opportunity to join the @maxperutzlabs.bsky.social and the @viennabiocenter.bsky.social as a Full Professor! www.nature.com/naturecareer...

9/ The observed patterns matched our model, and their parameters place these systems near the predicted optimal filtering regime -- These NPCs may act as efficient spatial thresholding filters! #Microscopy #QuantBio #Microtubules #UExM

In collaboration with the Posthaus Lab, we identify ANTXR2—also the anthrax toxin receptor—as the receptor for Clostridium perfringens NetF pore forming toxin. Cryo-EM shows extensive contact between the pore and the receptor 🧬🧊🔬 #Microbiology #CryoEM #PoreFormingToxins doi.org/10.1101/2025...

ICYMI: New online: Mouse radial spoke 3 is a metabolic and regulatory hub in cilia

After 5 amazing years @pilhoferlab.bsky.social I'm starting my lab @embl.org Grenoble this November embl.org/wollweber We'll image Asgard archaea and many other strange microbes ( #archaeasky, #protistsonsky..) to understand eukaryogenesis First job ad: #teamtomo scientist!🔬❄️ tinyurl.com/2rdu2ze6

Also in there some U-ExM pics and tomograms of #xenopus #deuterosomes #MCC

Woo! Very excited to share our collaborative work on the centriole's Luminal Distal Ring ⭕. This project started 13 years ago with @hugovdhoek.bsky.social & @stearnslab.bsky.social, and then beautifully came together with @computingcaitie.bsky.social & @centriolelab.bsky.social. #TeamTomo #UExM 🧪🧶🧬🔬

🚨 New preprint! Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM www.biorxiv.org/content/10.1...

Absolutely stunning work !! huge congratulations to the authors! The images are breathtaking, and I'm so excited to see @marinelap.bsky.social Cryo-ExM protocol working beautifully on diatoms.

Look at those #DIATOMS LOOK AT THESE #Microtubules Congrats to the team Long-live #UExM #Expansion #Microscopy

Happy to announce that the preprint about Retigene, our new gene atlas for inherited retinal diseases, is now on-line. www.biorxiv.org/content/10.1...

We have a preprint for you EHD2 forms rings on caveolae necks, in contrast to most EHDs forming helices. We determined its structure on membranes and show that N-term acts as a spacer By Elena, Vasya @vasiliimikirtumov.bsky.social, Jeff &Oli Daumke www.biorxiv.org/content/10.1...

We’re kicking off the DinoSphere Online Seminar Series! Join us for our first session with Karel Mockaer (Heidelberg) & Yong Heng Phua (OIST) 📅 1 July 9AM CEST 🔗 tinyurl.com/4mjaverj Spread the word! @protistwtmostest.bsky.social @ehehenberger.bsky.social @chandnibhickta.bsky.social&Norico Yamada

Share with your network, group members, colleagues & friends. We are extending the deadline till the 10th of June. This is your last chance of joining us this summer. #Science #ProtistsOnSky #Cell #Biology #Microscopy

👋 Are you looking for a postdoc position? Do you think microtubules are fascinating? Then we might have the job for you! 2-year funded postdoc to join our lab! 👉 deadline 20/06 👇 check it out www.godinholab.com

🔔 Rappel – AG de la SBCF, 5 juin 13h–16h30, Institut Cochin & en ligne 🔬 ✨ Prix Jeune Chercheur 2025 – Marine Laporte ✨ Présentations jeunes chercheurs ✨ Bilan & approbation des comptes 🔗 Zoom : ID 966 7570 3089 | Code 547574 tinyurl.com/2my3e9fv #SBCF #biologiecellulaire #jeuneschercheurs

New online: TRIM37 prevents ectopic spindle pole assembly by peptide motif recognition and substrate-dependent oligomerization

New online: Mesoscale regulation of microtubule-organizing centers by the E3 ligase TRIM37

New online: TRIMming centrosomal assemblies

📍I-PUB - Bd Carl-Vogt 20, Geneva 🗓Tuesday, May 20 – 6.30PM 🇬🇧 🔬 Seeing the invisible 🎟️FREE ENTRY ➡️https://pintofscience.ch/event/seeing-the-invisible-from-organelles-to-atoms @pintsworld.bsky.social #unigeneve #Pint25 #pintCH @centriolelab.bsky.social

A PhD position is available in my lab at the University of Geneva to explore the interaction between gut microbes and behavior in social bees. Please share with potential candidates. Application deadline: May 25th. More info and how to apply: tinyurl.com/PhDmgbee