Sophie G Martin
@sophiemartinlab.bsky.social
📤 2315
📥 487
📝 52
Professor @Biologie_UNIGE @MoCel_Geneva Loves cells under the microscope!
reposted by
Sophie G Martin
PomBase: The S. pombe knowledgebase
14 days ago
If you use PomBase, please help us to demonstrate our value, and make improvements by completing our user survey
www.surveymonkey.com/r/7GXJL6X
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reposted by
Sophie G Martin
PLOS Biology
16 days ago
How is
#cytokinesis
coordinated to ensure successful
#CellDivision
? Jian-Qiu Wu
@sophiemartinlab.bsky.social
&co show that the Ync13-Rga7-Rng10 module coordinates selective tethering & fusion of vesicles containing glucan synthases at the division site
@plosbiology.org
🧪
plos.io/43zJ35Z
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reposted by
Sophie G Martin
University of Cambridge
about 1 month ago
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the
@gurdoninstitute.bsky.social
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won:
https://bit.ly/4mM8o3r
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Super happy to see also this story out! 👇 7 years of amazing perseverance from
@gaowen.bsky.social
, who not only performed experimental evolution showing tradeoff between sexual and asexual reproduction, but also identified all key transcription and genome changes.
www.biorxiv.org/content/10.1...
add a skeleton here at some point
about 2 months ago
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Super excited that this story by
@borissieber.bsky.social
is now on BioRxiv! For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it ! See the thread 👇 and enjoy the paper!
doi.org/10.1101/2025...
add a skeleton here at some point
about 2 months ago
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reposted by
Sophie G Martin
Sebastian Soyk
about 2 months ago
Our department of Plant Molecular Biology at the University of Lausanne
@unil.bsky.social
is recruiting a Tenure-Track Assistant Professor in the field of Plant-Organism Interactions 🌱🐛🦠🍄! Application before November 30, 2025. See the official job ad for more details:
tinyurl.com/mtxdcz6p
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reposted by
Sophie G Martin
Marko Kaksonen
4 months ago
Hello microscopy and imaging experts and enthusiasts! We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English). Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
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reposted by
Sophie G Martin
Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
4 months ago
Come and Join our Dpt in Beautiful
#Geneva
! We are looking for a
#Microscopy
&
#Image
#Analysis
expert to help all of us at the Dpt.
add a skeleton here at some point
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reposted by
Sophie G Martin
Marko Kaksonen
5 months ago
How do cells switch on the actin assembly at endocytic sites? How can this on-switch evolve? Check out our new preprint!
www.biorxiv.org/content/10.1...
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reposted by
Sophie G Martin
Paul & Virginie - Centriole Lab
5 months ago
🚨 New preprint! Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with
@cellarchlab.com
@chgenoud.bsky.social
@stearnslab.bsky.social
🙌.
#TeamTomo
#UExM
www.biorxiv.org/content/10.1...
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reposted by
Sophie G Martin
Christian Fankhauser
5 months ago
Great job opportunity at The Center for Integrative Genomics, Lausanne University, Switzerland
unil.ch/cig/en/home....
For a tenure-track Assistant Professor position. More details for how to apply are here
nature.com/naturecareer...
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reposted by
Sophie G Martin
Jan-Willem Veening
5 months ago
New tenure track assistant professor position in molecular microbiology in our department
@dmf-unil.bsky.social
@unil.bsky.social
! We are casting a wide net for an experimental molecular microbiologist. Apply here:
wwwfbm.unil.ch/releve/appli...
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DMF: Tenure Track Assistant Professor towards Associate Professor in Molecular Microbiology - Site des postulations FBM
https://wwwfbm.unil.ch/releve/application/announce/show/133
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Beautiful images 🤩
add a skeleton here at some point
6 months ago
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reposted by
Sophie G Martin
New lab preprint! High resolution mapping of the actin fusion focus reveals myosin V-dependent transport of formin for actin aster compaction. A very cool work led by
@valthomas.bsky.social
and nice collaboration with Andrea Picco and
@kaksonen.bsky.social
!
www.biorxiv.org/content/10.1...
6 months ago
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The lab is on a roll. 2nd preprint in as many weeks! High levels of Cdc42 GTPase underlie an all-or-none decision to fuse. Great team effort led by PhD students
@sajjitasaha.bsky.social
and
@aiswaryasajeevan.bsky.social
www.biorxiv.org/content/10.1...
@biology-unige.bsky.social
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High levels of Cdc42 GTPase underlie an all-or-none decision to fuse
Cdc42 is a Rho-family GTPase conserved across eukaryotes, where it plays essential roles in cell polarization. In single-celled yeast systems, Cdc42 is a key driver of symmetry breaking and polarized ...
https://www.biorxiv.org/content/10.1101/2025.05.05.652171v1
6 months ago
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New lab preprint! High resolution mapping of the actin fusion focus reveals myosin V-dependent transport of formin for actin aster compaction. A very cool work led by
@valthomas.bsky.social
and nice collaboration with Andrea Picco and
@kaksonen.bsky.social
!
www.biorxiv.org/content/10.1...
6 months ago
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reposted by
Sophie G Martin
Paul & Virginie - Centriole Lab
7 months ago
New lab preprint! Unveiling the Molecular Architecture of T Cells and Immune Synapses with Cryo-Expansion Microscopy (Cryo-ExM). A fantastic collaboration with Dr. Benita Wolf. Congratulations to all authors, especially Florent Lemaitre, for leading this amazing work!
www.biorxiv.org/content/10.1...
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reposted by
Sophie G Martin
Samantha Butler
8 months ago
Important editorial from the EIC
@biologists.bsky.social
@dev-journal.bsky.social
about the current crisis in American science.
journals.biologists.com/dev/article/...
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Science under siege: protecting scientific progress in turbulent times
As Editors-in-Chief of The Company of Biologists' journals, we have been watching with growing concern the policy changes in the United States of America (USA) and the challenges that these are creati...
https://journals.biologists.com/dev/article/doi/10.1242/dev.204757/367342/Science-under-siege-protecting-scientific-progress
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reposted by
Sophie G Martin
Journal of Cell Science
9 months ago
In her Essay, Renata Basto highlights the huge budget cuts facing the scientific community in France. In response to the cuts, a group of researchers has formed the ‘Pour une Recherche d'Avenir’ initiative to secure the future of French research.
journals.biologists.com/jcs/article/...
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The importance of delivering Recherche d'Avenir – research for the future
In recent years, several European countries, including France, have reduced their investment in scientific research, with biomedical research taking a significant hit. The primary casualty is basic re...
https://journals.biologists.com/jcs/article/138/4/jcs263909/367071/The-importance-of-delivering-Recherche-d-Avenir
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reposted by
Sophie G Martin
Alexis Barr
9 months ago
Still hard to believe but Béla Novák died suddenly on Saturday. We've lost a fantastic colleague, mentor & great friend to many. There was really no-one else like him. Working with him was so much fun & I owe him a lot. All my thoughts are with his family.
www.merton.ox.ac.uk/news/remembe...
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Remembering Professor Béla Novák 1956 - 2025
With great sadness, we announce the loss of Professor Béla Novák.
https://www.merton.ox.ac.uk/news/remembering-professor-bela-novak-1956-2025
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reposted by
Sophie G Martin
Institut Jacques Monod
9 months ago
❗ Institut Jacques Monod Lectures❗ 📅 February, 7 📍 Institut Jacques Monod Next Friday, the Institut Jacques Monod lectures will welcome
@sophiemartinlab.bsky.social
, who will present «Signaling and actin focus architecture for cell-cell fusion». ➡️
buff.ly/3Pzjc79
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Looking forward to visiting the Institut Jacques Monod
@ijmonod.bsky.social
and a few days in Paris!
add a skeleton here at some point
10 months ago
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reposted by
Sophie G Martin
Institut Jacques Monod
10 months ago
#SaveTheDate
📅 February, 7 📍 Institut Jacques Monod The Institut Jacques Monod lectures will welcome
@sophiemartinlab.bsky.social
, who will present «Signaling and actin focus architecture for cell-cell fusion». ➡️
www.ijm.fr/event/instit...
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reposted by
Sophie G Martin
PLOS Biology
10 months ago
Nitrogen-starvation of
#FissionYeast
inactivates growth pathways (incl TORC1) & can trigger sexual reproduction.
@sophiemartinlab.bsky.social
use proteomic & phosphoproteomic changes during sexual development to show that TORC1 is reactivated by pheromone signaling 🧪
@plosbiology.org
plos.io/4h3OUVO
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reposted by
Sophie G Martin
PLOS Biology
10 months ago
Nitrogen-starvation of
#FissionYeast
inactivates growth pathways (incl TORC1) & can trigger sexual reproduction.
@sophiemartinlab.bsky.social
use proteomic & phosphoproteomic changes during sexual development to show that TORC1 is reactivated by pheromone signaling 🧪
@plosbiology.org
plos.io/4h3OUVO
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15
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reposted by
Sophie G Martin
PLOS Biology
10 months ago
Nitrogen-starvation of
#FissionYeast
inactivates growth pathways (incl TORC1) & can trigger sexual reproduction.
@sophiemartinlab.bsky.social
use proteomic & phosphoproteomic changes during sexual development to show that TORC1 is reactivated by pheromone signaling
@plosbiology.org
plos.io/4h3OUVO
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reposted by
Sophie G Martin
Nicolas Minc
10 months ago
Our lab has multiple open positions for post-docs to study the regulation and function of cytoplasm mechanics during embryo development. Details below 👇👇 Please Repost !!!
@ijmonod.bsky.social
@cnrs.bsky.social
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End-of-year read! The work of Melvin Bérard in the
@sophiemartinlab.bsky.social
is now out in
@plosbiology.org
. Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast
doi.org/10.1371/jour...
11 months ago
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reposted by
Sophie G Martin
The Company of Biologists
12 months ago
We are happy to report that our journals and community sites now have Bluesky accounts. Follow them at:
@dev-journal.bsky.social
@jcellsci.bsky.social
@jexpbiol.bsky.social
@dmmjournal.bsky.social
@biologyopen.bsky.social
@the-node.bsky.social
@prelights.bsky.social
@focalplane.bsky.social
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reposted by
Sophie G Martin
PomBase: The S. pombe knowledgebase
12 months ago
go.bsky.app/D63c48C
add a skeleton here at some point
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reposted by
Sophie G Martin
🧬Jacob L Steenwyk
about 1 year ago
Yeast starter pack courtesy of
@maxhaase.bsky.social
!
go.bsky.app/PyUwqLU
add a skeleton here at some point
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Just back from fantastic
@cshlaboratory.bsky.social
membrane and cell fusion meeting. Thanks to Andi Pauli, Elisabeth Chen and Mark Rose for the great organisation. See you in two years!
about 1 year ago
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The Martin lab has an open postdoc position at the interface of
#cytoskeleton
and
#condensate
biology, in a fantastic research community! If interested, do not hesitate to contact us:
mocel.unige.ch/research-gro...
Please RT!
about 1 year ago
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On BioRxiv, the PhD work of Melvin Bérard, with help of Laura Merlini: TORC1 reactivation by pheromone signaling revealed by phosphoproteomics of fission yeast sexual reproduction. Enjoy the read!
biorxiv.org/content/10.1...
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TORC1 reactivation by pheromone signaling revealed by phosphoproteomics of fission yeast sexual reproduction
Starvation, which is associated with inactivation of the growth-promoting TOR complex 1 (TORC1), is a strong environmental signal for cell differentiation. In the fission yeast Schizosaccharomyces pombe, nitrogen starvation has distinct physiological consequences depending on the presence of mating partners. In their absence, cells enter quiescence, and TORC1 inactivation prolongs their life. In presence of compatible mates, TORC1 inactivation is essential for sexual differentiation. Gametes engage in paracrine pheromone signaling, grow towards each other, fuse to form the diploid zygote, and form resistant, haploid spore progenies. To understand the signaling changes in the proteome and phospho-proteome during sexual reproduction, we developed cell synchronization strategies and present (phospho-)proteomic datasets that dissect pheromone from starvation signals over the sexual differentiation and cell-cell fusion processes. Unexpectedly, these datasets reveal phosphorylation of ribosomal protein S6 during sexual development, which we establish requires TORC1 activity. We demonstrate that TORC1 is re-activated by pheromone signaling, in a manner that does not require autophagy. Mutants with low TORC1 re-activation exhibit compromised mating and poorly viable spores. Thus, while inactivated to initiate the mating process, TORC1 is reactivated by pheromone signaling in starved cells to support sexual reproduction. ### Competing Interest Statement The authors have declared no competing interest.
https://biorxiv.org/content/10.1101/2024.06.04.597361v1
over 1 year ago
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Two weeks to the deadline for short talk selection. Submit your abstracts !!
over 1 year ago
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New preprint alert! Alejandro Melero with help from Olivia Muriel and Miguel Basante-Bedoya shows that Arp2/3-dependent actin assembly shapes endosomes and promotes intracellular trafficking in fission yeast, despite absence of known regulators.
www.biorxiv.org/content/10.1...
over 1 year ago
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To all lovers of the
#cytoskeleton
: Do not miss the Plant and Microbial Cytoskeleton GRC and GRS 2024: Functional Diversity of the Cytoskeleton Great line-up of speakers! Check the website to register:
www.grc.org/plant-and-mi...
over 1 year ago
0
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To all lovers of the
#cytoskeleton
: periodic reminder to register for the Plant and Microbial Cytoskeleton GRC and GRS 2024! Great line-up of speakers! Check the website to register:
grc.org/plant-and-mi...
Please spread the word!
almost 2 years ago
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reposted by
Sophie G Martin
Marc Somssich
almost 2 years ago
Plant and Microbial Cytoskeleton Gordon Research Conference Functional Diversity of the Cytoskeleton Organized by
@sophiemartinlab.bsky.social
, Alexander R. Paredez, Alex Bisson & Sabine Mueller August 11 - 16, 2024 Speakers include
@carolynplants.bsky.social
&
@schneiderlab.bsky.social
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Very excited to advertise the Plant and Microbial Cytoskeleton GRC 2024: Functional diversity of the cytoskeleton. Co-organized with Alex Paredez, Sabine Müller and Alex Bisson. Great line-up of speakers! Check the website and register:
www.grc.org/plant-and-mi...
almost 2 years ago
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So cool! Publish in or review for the Journal of Cell Science and a tree is planted or protected. This is my protected 🌳
forest.biologists.com/landscape/?i...
almost 2 years ago
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reposted by
Sophie G Martin
Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
almost 2 years ago
Humbled to join the EMBO YIP community. I'm thankful to my amazing team (Marine O.,
@hiralshah.bsky.social
, Margarida A.), mentors (
@sophiemartinlab.bsky.social
, P. Gönczy), funding (
@snsf-ch.bsky.social
, EPFL), and many awesome collaborators. (1/2)
www.embo.org/press-releas...
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Are you an ASCB member? Submit you work to MBoC. From today, all members’ papers thoroughly reviewed. No desk rejection!
almost 2 years ago
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En route for
#cellbio2023
🚌🚃🛫 Looking forward to great science and seeing many 😀 We present one talk (by PhD student Melvin Bérard Sunday 4:15pm, room 254A) and two posters (Monday and Tuesday 12:15)
almost 2 years ago
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Looking forward to meeting new and old colleagues and learning much about plant cell biology !
add a skeleton here at some point
almost 2 years ago
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reposted by
Sophie G Martin
Hiten Madhani
about 2 years ago
The Madhani lab at UCSF is hiring a tech! Ideal opportunity to obtain additional experience before grad school! Apply here:
rb.gy/c8oscf
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reposted by
Sophie G Martin
The Dpt of Molecular and Cellular Biology at the University of Geneva is recruiting an SNSF assistant professor. Come join us! It's a great environment and we offer generous support! Apply by Oct 31st and/or spread the word!
mocel.unige.ch/education-an...
about 2 years ago
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The Dpt of Molecular and Cellular Biology at the University of Geneva is recruiting an SNSF assistant professor. Come join us! It's a great environment and we offer generous support! Apply by Oct 31st and/or spread the word!
mocel.unige.ch/education-an...
about 2 years ago
1
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