Activating and repressing in the same cell: the dream came true in human induced pluripotent stem cells. Highlight prepared at the PEPR Cell-ID meeting. Includes an insightful response from #preprint authors Elisa Balmas & @berterolab.bsky.social #preLight⬇️ prelights.biologists.com/highlights/c...

1/ Excited to share our new bioRxiv preprint! "4D spatial transcriptomics reveals nodule identity emerges through stacked parallel developmental programs" 📄 doi.org/10.64898/202... Using Xenium, we generated a 4D (3D space + time) atlas of nodule development in Medicago truncatula.

Bringing together science & art, @manuelthery.bsky.social & the CytoMorpho lab describe their project on how cells adapt their shape to their environment using the Musée d’Orsay as their template! The full performance was presented over two nights at the museum earlier this year. #sciart #cellbio

Marta San Martin highlights work that identifies defective BRCA1-dependent DNA end resection as a key driver of tandem duplication formation & FANCM synthetic lethality. #preprint Namrata M. Nilavar, @albertomarin.bsky.social & colleagues #MolBio #preLight⬇️ prelights.biologists.com/highlights/d...

📢Check out our latest preprint list on FocalPlane In this list, we focus on the latest tools and techniques in imaging, including sample prep, probes, hardware and software. focalplane.biologists.com/2026/06/26/m... Let us know if you've been reading a preprint that we should add to our list.

Spectacular preprint led by @sydsat.bsky.social in @ohnolog.bsky.social lab, @uwgenome.bsky.social. Neutrophils precede gastrulation in killifish and rapidly patrol the yolk. (1/2)

We’ve integrated @prelights.bsky.social into one of our MSc classes! Been working really well so far! prelights.biologists.com/profiles/umo...

Don't use slop. Someone's trying to make money out of you and your colleagues and your friends. Do yourself a favor and read 100% human-crated content in @prelights.bsky.social Upload preprints. Read preprints. Cite preprints. Fuck AI 🧪

An organelle changes careers 💼 In fly sperm cells, the cell's ribosome factory becomes a hub where fertility genes, silenced everywhere else, are switched on. Entertaining #preLight by Panagiotis Giannios on work from the Yamashita Lab #preprint #DevBio 👀⬇️ prelights.biologists.com/highlights/d...

From cells to amino acids: 1000ExM pushes expansion microscopy even further 🔬 #microscopy @fadelvalle.bsky.social covers an impactful #preprint from the labs of @bergerlab.bsky.social, @alishaib.bsky.social, Silvio Rizzoli & @eboyden3.bsky.social #preLight⬇️ prelights.biologists.com/highlights/t...

🔬🔦In this Imaging spotlight, Benita Wolf and team share their research dissecting the human cytotoxic IS using cryo-ExM. They include their top tips for optimising cryo-ExM, or as they say “(Here are) A few things we learned the hard way that might save others time!” @centriolelab.bsky.social

I am thrilled to share my PhD work with @nicolettapetridou.bsky.social @embl.org: www.biorxiv.org/cgi/content/... A fun collaboration with Bernat Corominas-Murtra, Adrián Aguirre-Tamaral, @bart-smeets.bsky.social , Jef Vanghel and Tom Belpaire! Read the story in the comments below ⤵️

Into the Killiverse! 😏 New tool from @param-p-singh.bsky.social et al 🐟 #killifish 🔗 to explore: killiverse.org

From tip to centre: positional identity drives cell fate in the brown alga Ectocarpus 🪸 🌿 Urvashi Goswami highlights a recent #preprint from the Charrier Lab @brownalgaedev.bsky.social #DevBio Check it out 👀⬇️ prelights.biologists.com/highlights/c...

📢 (1/2) Excited to share the first preprint from my PostDoc! We developed UbSeRP to map co-translational ubiquitination in a translatome-wide, revealing thousands of quality control sites, and how they reshape with aging. www.biorxiv.org/content/10.6... #proteostasis #ribosomes #preprint

Double preprint! 👇 Check out our latest studies on timing, heterogeneity and collective behaviour (with a fun tiny bonus on evolution!) 1. www.biorxiv.org/content/10.6... 2. arxiv.org/abs/2605.13234

Start-Codon Recognition: The inhibitory effect of 2'-O-methylation In their #preprint, Adam Suh, @danyarango.bsky.social & team examine the function of the epitranscriptome specifically in relation to the initiation of translation #preLight by Leonie Brüne prelights.biologists.com/highlights/s...

IMPORTANT study from @hocinerekaik.bsky.social @denisduboule.bsky.social and a significant validation of SCBEMs, #gastruloids in particular, as a discovery tool www.biorxiv.org/content/10.6... 🧵

Of frogs and men 🐸 Javiera Jorquera, Cecilia Arriagada & team studied the dynamic morphology of the second heart field in developing frog embryos & the contribution of Fibronectin 1 to this process. #preprint #DevBio #preLight by Theodora Stougiannou prelights.biologists.com/highlights/f...

🎉 I'm thrilled to share SMLMFlow: my first first-author paper for my PhD! 📰 Preprint: www.biorxiv.org/content/10.6... 🧵👇1/5

It was fun to contribute to @dev-journal.bsky.social “In preprints” series and cover this beautiful preprint on mechanics and epithelial multilayering - check it out!

There’s still time to vote in our image competition in collaboration with #ELMI2026. The conference kicks off tomorrow, in more ways than one, with the Core Facility Day and the ever-popular Academy vs Industry football match! focalplane.biologists.com/2026/06/08/f...

Timing is everything - also for your immune system⏰ Temitope Oshinowo & team demonstrate that the circadian clock programs host susceptibility in the intestine, before infection occurs. #preprint #immunology Read the #preLight by Owen Ang + author response👇 prelights.biologists.com/highlights/c...

We are thrilled to announce our new preprint from the wonderful @sorayavillaseca.bsky.social Ever wondered how cells squeeze through tiny spaces in embryos? Neural crest cells use Dynein to transport their nucleus along microtubules. Check out the preprint!! www.biorxiv.org/content/10.6...

Happy to share our newest preprint. We developed guidelines and analysis workflows for FLIM Imaging in plants. Multiplexing with spectrally overlapping fluorophores in plants is now possible. Have a look. Any feedback is more than welcome. www.biorxiv.org/content/10.6...

Cats: the ultimate pets and scientific heroes. 🐱 Studying feline viruses to identify innovative solutions to prevent human infections. #preprint by @cb99-lewis.bsky.social, @dbhella.bsky.social & team #microbiology #preLight by @orestissavva.bsky.social: prelights.biologists.com/highlights/i...

CXADR – an encouraging new (potential) biomarker for Ewing Sarcoma Members of the @philipplange.bsky.social Lab highlight work from Alina Ritter & colleagues that presents a powerful example of bench-to-bedside research strategies. #preprint #preLight: prelights.biologists.com/highlights/t...

What can the oldest recorded female rhesus macaque teach us about #ageing? 🐒 This #preprint highlight prepared by Stefan Wirth discusses dementia-like symptoms and how they shaped her behaviour - and what it means for geriatric animal welfare. #preLight: prelights.biologists.com/highlights/b...

1/🧵 Can transcription factor condensate formation be explained without phase separation? Our new preprint introduces SPARK, a simulation tool that reproduces condensate behavior (clustering, fusion, FRAP) from diffusion & binding kinetics alone. Movie: 60 sec FRAP sim www.biorxiv.org/content/10.6...

There are so many fun ways to approach research dissemination! Tried the @prelights.bsky.social spotLight video format to share our latest published work on how ZIC2 shapes early neural development! Total YouTuber vibes: and I kinda' loved it, tbh. 🤳🔬👇 youtu.be/V_yMoWMkZCM

Does ribosome function decline over time? ⏳ The recent #preprint by @jbotello.bsky.social & team @brangwynnelab.bsky.social delves right into this question. Scott Murray Cors highlights this work in his first post. #CellBio #genetics #preLight: prelights.biologists.com/highlights/r...

Over the past year, @biologyopen.bsky.social has expanded its Fast & Fair initiative to accelerate peer review. The results are impressive - take a look at their latest preprint to find out more: www.biorxiv.org/content/10.6...

(1/11) Excited to share the brand-new cell division preprint from the lab! In this manuscript, chemical biology (in a collaboration with @rnett42.bsky.social Ryan’s lab) meets the cell biology (our lab). Harmala alkaloids regulate cell division planes in plants www.biorxiv.org/content/10.6...

Have you ever wondered if fish yawn? (and if they do, what that tells us about yawning?) The first preprint from the lab and a serendipitous observation ⬇️ www.biorxiv.org/content/10.6...

ICYMI - we're hosting a new quarterly webinar series on cell migration! In our first webinar on Thursday 11 June at 15:00 BST (UTC+1), we'll hear talks from @juanmagararc.bsky.social, @kyohalie.bsky.social & @djcohen.bsky.social. focalplane.biologists.com/2026/05/29/n...

Gut feeling about ageing: intestinal ceramidase Asah2 as a conserved regulator of vertebrate lifespan. Jeny Jose highlights a #preprint that addresses the fascinating question: What controls the rate at which we age? ⌛ Check out the #preLight to learn more: prelights.biologists.com/highlights/i...

61 species, 13 phyla, one simple geometric rule that appears to set when every embryo starts speaking through its own genome. 🧬 Panagiotis Giannios highlights a recent #preprint from @mirimiam.bsky.social & collaborators. #EvolutionaryBiology #preLight: prelights.biologists.com/highlights/e...

As marine heatwaves intensify, who survives - and why? Maitri Manjunath highlights work from @zoe-meziere.bsky.social & team who studied the variation in coral thermal stress responses during a real-time marine heatwave 🪸 #preprint #ecology #preLight: prelights.biologists.com/highlights/h...

Our latest preprint list is now up on FocalPlane. Check it out here: focalplane.biologists.com/2026/05/29/m...

Excited to share our latest research on leveraging machine learning with helical fusions for the design of novel protein cages! Preprint: “Design and structure of protein cages based on helical fusion and machine learning” Link: www.biorxiv.org/content/10.6...

Gut microbiome changes over the course of multiple sclerosis differentially influence autoimmune neuroinflammation This study from the labs of Maria José Sá and Carles Ubeda highlights how complex diseases like MS require multidisciplinary approaches. prelights.biologists.com/highlights/g...

Prenatal Stress Differentially Shapes Adult Behavior in Male and Female Offspring Study from the lab of @stephaniegorka.bsky.social elucidates the mechanisms underlying sex-specific vulnerabilities to prenatal stress. ♂️♀️ prelights.biologists.com/highlights/p...

Weekend read: head to @prelights.bsky.social website and read a preprint about Sun2 role in mechanosensing-driven extracellular matrix production and lung fibrosis, chosen by Beth Chopak. Prelight: bit.ly/4ucTbgj Preprint: doi.org/10.64898/202...

ASCL1 can’t always make neurons alone… In this 2‑minute #Short, jethrolb.bsky.social explains how chromatin priming and co‑factors shape cell fate decisions in embryonic stem cells. #StemCells #DevBio www.youtube.com/shorts/UB2es...

preLighters’ choice – A curated selection of recent preprints In this post on the Node, read concise #preprint highlights of recent #DevBio and #StemCell biology papers prepared by the @prelights.bsky.social community. thenode.biologists.com/prelighters-...

Aquatic adventures in heart regeneration❤️ Study from the lab of @simoesfilipa.bsky.social looks at zebrafish hearts after cryoinjury to identify ligand-receptor circuits and macrophage states that facilitate #regeneration. #preprint #preLight by Theodora ⬇️ prelights.biologists.com/highlights/c...

🚨Happy to share a new PreLight covering the latest #preprint by the Meissner lab (@molgen.mpg.de) on acute SUZ12 degradation during TLS formation. A work brilliantly executed by @dannimklee.bsky.social et al. Get to know more about him and his work here ⤵️ prelights.biologists.com/highlights/t...

Friction at the tip keeps the Drosophila germ band straight against innate instabilities. #DevBio Ruoheng Li highlights a #preprint from @giuliaserafini.bsky.social & colleagues @paveltomancak.bsky.social Lab #preLight + an insightful author response 👀⬇️ prelights.biologists.com/highlights/e...

The challenge of in vitro gametogenesis. #DevBio Alan Leung highlights a #preprint from the Hamer’s Lab that identifies the specific metabolites and proteins in immature hPGCLSc that could create a maturation bottleneck. #preLight + an author response ⬇️ prelights.biologists.com/highlights/h...

Science is a story – join the communities that tell it. Every experiment has a backstory. Every figure, failure and breakthrough is shaped by people, choices and chance. If narratology is about how stories are told and why they matter, then science is rich with narratives waiting to be uncovered.