Angela Fan, @yoldasyildiz.bsky.social & co show the importance of studying alcohol effects in more realistic systems that reflect the complexity of the living brain, showing that alcohol during adolescence can affect RNA regulation in very specific ways. 🧠https://doi.org/10.1242/bio.062010

Arnon Pudgerd and colleagues show that ecdysteroid stimulated bursicon expression and improved the immune response against bacterial challenges. doi.org/10.1242/bio....

To know about Daisy's experience of publishing with @biologyopen.bsky.social, read this Editorial: doi.org/10.1242/bio....

We are featuring Daisy Pineda-Suazo, who was interviewed for @biologyopen.bsky.social's ‘First Person’ series in 2024 after her first-author publication in the journal, as an extraordinary biologist. #100biologists #NPAW2025

To celebrate the #NPAW2025 theme of communicating your science and research, we share advice and tips from our #SciCommConnect webinar, which discussed practical ways to help researchers deliver their message. Find out more bit.ly/3K6GeCC #LovePostdocs

Congratulations to the winners of our image competition with the @mblscience.bsky.social Embryology course. The winner of the Editor’s choice is an image of a anole lizard eye, acquired by Arthur Boutillon @campaslab.bsky.social. thenode.biologists.com/results-from... #devbio 🔬🎉

Congratulations to the winners of our image competition with the @mblscience.bsky.social Embryology course. The winner of the popular vote is a mouse embryo stained for Sox9 (cyan) alpha-tubulin (yellow) & endomucin (magenta) from Nicole Roos & Anthony Wokasch. thenode.biologists.com/results-from...

Sivasengh & co identify PER3 as a novel circadian regulator of GLUT4 translocation, a key step in glucose uptake, and insulin sensitivity in skeletal muscle using a live-cell GLUT4 translocation assay capable of capturing circadian dynamics in skeletal muscle cells. doi.org/10.1242/bio....

On the cover: A zebrafish cx41.8tq/tq mutant embryo treated with H202, stained to visualise the expression of gata2b, which marks haemogenic endothelium along the trunk of the embryo. Explore Issue 8: bit.ly/4nlTsK1

The choroid plexus of the lateral ventricle is one of the main sources of cerebrospinal fluid, but not much is known about its development. Sam Moore & colleagues now investigate the role of the transcription factor Mllt11 in forming the choroid plexus. doi.org/10.1242/bio....

Anabel Byars & Nicole Riddle investigate how unpredictable disturbance impacts animal activity and the lifespan of genetically diverse populations of fruit flies. doi.org/10.1242/bio....

Vishwas Konde & co give insight into the novel role of RALA S194 phosphorylation in regulating tumour formation in cancer cells. They also show that this regulation of tumour formation stems from its role in RALA localisation rather than RALA activation. doi.org/10.1242/bio....

To expand the Fast & Fair peer review experiment to more subject areas, we are inviting our community members to join the Biology Open peer reviewer pool. Your participation and commitment are key to the success of this initiative. Apply at bit.ly/428Cszt #fastandfairpeerreview

Katherine Fisher & co address the contribution of the RNA-binding proteins Imp and Syp, as well as their target transcription factor Chinmo, during the development of the fruit fly embryonic central nervous system. doi.org/10.1242/bio....

We have received wonderful feedback from authors who have benefited from Read & Publish agreements arranged by their institutional libraries. To read what authors have to say about fee-free Open Access publishing in Biology Open, visit bit.ly/4d59CDN.

Subhradip Das et al. reveal that Caspar plays a central role in the early development of future reproductive cells in fruit fly embryos. doi.org/10.1242/bio....

Christoph Bruns & co investigate whether the primary mechanism during joint movement in locust legs is membrane stretching or folding and found that the membranes connecting the hard leg segments of the exoskeleton have a very characteristic folding. doi.org/10.1242/bio....

On the cover: The California two-spot octopus in its natural habitat off Catalina Island, California. Gendreau & co investigated how multiple arms are recruited to find & manipulate prey & other objects of interest using chemotactile exploration in lab experiments. Explore Issue 7: bit.ly/3JGLr45

preLighters go live! A light and lively face-to-face conversation between the preLighters @fadelvalle.bsky.social & Vibha Singh and the researchers probablycarmen.bsky.social & Eva Mejia-Ramirez will be hosted at the @focalplane.bsky.social webinar. 4 Sept, 14.00-15.00 BST Tune in!

Excited to share that the final version of our work on Connexin 41.8 in HSPC specification is out now in @biologyopen.bsky.social! If you're curious about how a connexin helps turn endothelial cells into blood stem cells, please have a read! journals.biologists.com/bio/article/...

Hans Ulrik Riisgård and Poul S. Larsen verify the hypothesis that allometric scaling factors are the same for filtration and metabolic rate in filter-feeding marine invertebrates. doi.org/10.1242/bio....

#FocalPlaneFeatures meets @prelights.bsky.social @fadelvalle.bsky.social & Vibha Singh have picked 2 fantastic #cellbio preprints & will be presenting their preLights alongside research talks from @probablycarmen.bsky.social & Eva Mejia-Ramirez. Register: focalplane.biologists.com/2025/08/20/f...

Atrial fibrillation (AF) is a common arrhythmia that increases the risk of stroke & heart failure. Ting Chen & co generate a spontaneous AF mouse model via CRISPR/Cas9, highlighting the DYNLT1-TMCO1 axis in ER calcium overload & offering new insights into AF mechanisms. 🫀 🐭 doi.org/10.1242/bio....

Can peer review be done faster, without compromising on quality? Biology Open has embarked on an exciting experiment to find out - Editor-in-Chief Dan Gorelick @danielgorelick.bsky.social explains. www.youtube.com/watch?v=Tt5h...

Kramer & Sylvester show that the shape of an australopithecine pelvis in a modern human body produces higher hip muscle activations for gluteus medius, but lower activations for gluteus maximus. doi.org/10.1242/bio....

Claudia Collier & co show that exposure to a chemical linked to Gulf War illness can change how the colon moves by affecting the nerves and immune cells that help control gut function. doi.org/10.1242/bio....

We are committed to improving equity, diversity and inclusion (EDI) in all our activities. Click on the image to read why we have adopted the C4DISC Joint Statement of Principles, and are signatories of the Joint commitment for action on inclusion and diversity in publishing. @c4disc.bsky.social

Can peer review be done faster, without compromising on quality? Biology Open has embarked on an exciting experiment to find out - Editor-in-Chief Dan Gorelick explains. www.youtube.com/watch?v=Tt5h...

Our next extraordinary biologist is Andrea Paterlini, the first early-career researcher highlighted in @biologyopen.bsky.social's 'Future Leaders to Watch' series, who also wrote a 2023 Review for BiO's ‘A Year at the Forefront of…’ collection. #100biologists @apaterlini.bsky.social

Amena Ali Alsakran & co from @exeter.ac.uk use zebrafish embryos as a model for studying human foetal alcohol spectrum disorders, focusing on gene expression and cell movement during gastrulation. doi.org/10.1242/bio....

Myrofora Panagi & co from @ucy1.bsky.social use the fruit fly hindgut epithelium to uncover adjunct nodes of pro-metastatic RasV12 signalling—opening doors to new therapeutic targets. 🪰 doi.org/10.1242/bio.... #Drosophila #Oncogene

Kidneys use urea transporters to move urea into urine. Now, Neydiana Pina-Lopes & co show that these murine transporters not only move urea but also help conserve water by concentrating urine and transporting ammonia. doi.org/10.1242/bio....

Would you like to be the Node’s new Community Manager? If you're interested in #SciComm and passionate about #DevBio, apply to join the @dev-journal.bsky.social & @biologists.bsky.social team. Find out more about what the role entails: bit.ly/4otQ2GL #JobOpportunity

Maternal protein restriction delays the differentiation of epididymal mesenchymal cells in newborn rats. Now, Colonheze et al. show that it also impairs cell differentiation in the epididymal epithelium in the final phase of epididymal differentiation. doi.org/10.1242/bio.... #ProteinRestriction

We have received wonderful feedback from authors who have benefited from Read & Publish agreements arranged by their institutional libraries. To read what authors have to say about fee-free Open Access publishing in Biology Open, visit bit.ly/4d59CDN.

Huy Tran, @docteuredesmouches.bsky.social & team present EyeHex, a tool for automatic segmentation of fruit fly compound eyes. EyeHex offers a cost-effective, rapid and flexible pipeline for extracting detailed statistical data on Drosophila compound eye variation 🪰👁️. doi.org/10.1242/bio....

I feel wonderful being a part of this meeting review alongside @ritikamukherji.bsky.social and Kamakshi. Thanks to @melnattur.bsky.social and all the co-organizers for this opportunity and their valuable inputs. journals.biologists.com/bio/article/...

Can peer review be done faster, without compromising on quality? Biology Open has embarked on an exciting experiment to find out - Editor-in-Chief Dan Gorelick @danielgorelick.bsky.social explains. www.youtube.com/watch?v=Tt5h...

The adaptive origin of bipedalism is one of the foundational transitions in human evolution. Kramer & Sylvester compare musculoskeletal models of modern human and australopithecine-like hips to explore how changes in hip morphology affect muscular activation. doi.org/10.1242/bio....

Thank you Christoph Kurze for sharing your experience of fee-free Open Access publishing in @biologyopen.bsky.social. Read Christoph’s paper: doi.org/10.1242/bio.... See if your institution is participating: www.biologists.com/library-hub/... #Publishing #OpenAccess #OA #ReadAndPublish #Academia

The protease furin acts as an intracellular chaperone during the intoxication pathway of #recombinantimmunotoxins based on Pseudomonas exotoxin A. Using a furin knockout cell line, Grossman & co conclude that both furin cleavage and trafficking contribute to intoxication. doi.org/10.1242/bio....

Sanjib Das and team introduce an efficient mouse model for prophylactic and therapeutic studies using surgical intervention by directly injecting H. pylori inoculum into the stomach. This resulted in severe infection in 7 days. 🐭 🧪 doi.org/10.1242/bio.... #AnimalModel

In this Editorial, @reinierprosee.bsky.social and @katherine-brown.bsky.social explore the transformation of the preprint landscape since 2013 and how @biologists.bsky.social has adapted to and embraced this (new) way of sharing research. doi.org/10.1242/bio....

I spoke with Alejandra Clark and @danielgorelick.bsky.social about the fast and fair peer review initiative from @biologyopen.bsky.social. They’re cutting down review times and compensating peer reviewers for their work! #PeerReview #FastAndFair (2/5) www.youtube.com/watch?v=mM6m...

Phase II of our Fast & Fair peer review experiment is testing scalability. Results so far are promising. Read more at bit.ly/41N31tO. #FastandFairPeerReview #PeerReview #ScientificPublishing

Our latest research on the development of the lateral ventricule choroid plexus is published and online: doi.org/10.1242/bio.... The study was led by a former graduate student Sam Moore, with help from postdocs Drs Danielle Stanton-Turcotte and Emily Witt. (1/2)

In this Meeting Review article, Gonzalo Germán Guendulain & co showcase the latest workshop of the Argentine Group for Extracellular Vesicles, emphasizing its impact in fostering national and international collaborations. doi.org/10.1242/bio....

Our Editor-in-Chief, Daniel Gorelick @danielgorelick.bsky.social , reviews Biology Open’s performance for the year 2024 in this Editorial.

Explore our June issue: bit.ly/3GQHN6o On the cover: Pierre & co investigate the diamond-backed terrapin's osmoregulatory strategy, enhancing our ability to assess how this species may respond to projected changes in coastal habitats due to sea level rise.

Neutrophils & monocytes are sentinels of inflammatory signals, migrating along endothelial boundaries to reach sites of action. Honig & co show that #neutrophils & #monocytes migrate along endothelial cell boundaries in vitro to optimise search efficiency. 🔬 doi.org/10.1242/bio....