Looking forward to @thebacr.bsky.social #Tumour Microenvironment and 3D #Cancer Modelling Workshop starting today! Come visit our table to chat to Senior Editor @kirstyhooper.bsky.social about the cutting-edge cancer research we publish:

Final chance to register for the @fusionconf.bsky.social 4th Metabolism in Health & Disease conference, 10 - 13 October in Portugal. 📆Registration closes 13 July 2026 📌Poster slots available Click here for the programme, abstract & grant opportunities available: bit.ly/4cQeQW6

Completely unable to resist anything that mentions #cats. Inhibition of VP2-mediated entry: a potential antiviral strategy to treat or prevent calicivirus disease prelights.biologists.com/highlights/i...

There are so many fun ways to approach research dissemination! Tried the @prelights.bsky.social spotLight video format to share our latest published work on how ZIC2 shapes early neural development! Total YouTuber vibes: and I kinda' loved it, tbh. 🤳🔬👇 youtu.be/V_yMoWMkZCM

Have you seen Cancer Conference Hub - @helloeacr.bsky.social calendar of cancer research conferences? You can add your event too. See more at bit.ly/4u1L6LP #CancerResearch

Looking forward to the @cclguk.bsky.social symposium on the developmental origins of paediatric cancers at the @crick.ac.uk on Monday! As @dmmjournal.bsky.social are sponsoring, we will have a table, so come chat! www.cclg.org.uk/information-...

Claudia Kleinman @claudiakleinman.bsky.social is speaking on 'From robust cell fates to plastic states: Lineage constraints in pedi brain tumors' at our Journal Meeting in October #DMM2026cancer #pediatriccancer Register to attend: biologists.com/meetings/dmm... Early-bird deadline: 19 June 2026

In this new paper Hiramuki, Jones & co show that cre-reporter mouse lines expressing human DUX4 regulatory elements can be used as discovery tools for developmental processes and mechanisms underlying #FSHD (Facioscapulohumeral muscular dystrophy) doi.org/10.1242/dmm....

Hats off to the winner of our 2025 Outstanding Paper Prize for Resources & Methods articles - Victoria Ektnitphong @ UT Southwestern Medical Center Ektnitphong and colleagues describe a humanized lung-on-a-chip model that offers new insights into TB.

Lena Kutscher @lenakutscher.bsky.social is speaking on '2D and 3D models of embryonal brain tumor initiation' at our Journal Meeting this October #DMM2026cancer #pediatriccancer Register to attend: biologists.com/meetings/dmm... Early-bird deadline: 19 June 2026

In this new paper Kolesnikova, Ellederova & co generate a knock-in minipig model with an expanded HTT allele to recapitulate early molecular characteristics of #Huntingtonsdisease, providing a valuable platform for evaluating emerging therpaies 📰 doi.org/10.1242/dmm....

🏆 Congratulations to the DMM 2025 Outstanding Paper Prize winner for Research Articles: Joshua D. Ginzel @Duke University School of Medicine. Read our Editorial to learn more about the winner & their research. doi.org/10.1242/dmm....

Weekend read: head to @prelights.bsky.social website and read a preprint about the mechanisms underlying sex-specific vulnerabilities to prenatal stress, chosen by Alice Gennevois, Ariane Delisle, uMontreal Neuro preLighters. Prelight: bit.ly/4wC0jVs Preprint: doi.org/10.64898/202...

Congratulations to DMM Editorial Advisory Board member Paul Riley (dpag.ox.ac.uk/research/ril...) on being elected to the Fellowship of the Royal Society.

ASCL1 can’t always make neurons alone… In this 2‑minute #Short, jethrolb.bsky.social explains how chromatin priming and co‑factors shape cell fate decisions in embryonic stem cells. #StemCells #DevBio www.youtube.com/shorts/UB2es...

Check out our Editor's Choice from Carbrera, Mohamed, @danielgorelick.bsky.social & co @bcmhouston.bsky.social on how folate & magnesium can prevent developmental toxicity caused by a common #HIV drug in #zebrafish Highlight & article: ⚡ doi.org/10.1242/dmm.... 📰 doi.org/10.1242/dmm....

JCS congratulates our Editor-in-Chief Michael Way @drmichaelway.bsky.social on his election as a Fellow of the Royal Society, the UK’s national academy of sciences. royalsociety.org/news/2026/05...

Timothy Phoenix is speaking on 'Modeling CNS tumors to advanced basic and translational discoveries' at our Journal Meeting this October #DMM2026cancer #pediatriccancer #cancer Register to attend: biologists.com/meetings/dmm... Early-bird deadline: 19 June 2026

In our April Patient Voice feature, we spoke with Liz and Jay Scott about Alex’s Lemonade Stand Foundation—their mission, the collaborative efforts between physicians, researchers, families, and patient advocates, and their vision for the future. doi.org/10.1242/dmm....

“One never really knows when a basic science finding will transform translational research…" ”From comparison to mechanism: decoding heart regeneration thenode.biologists.com/from-compari...

Mimi Bandopadhayay @bandolab.bsky.social is speaking on 'Anti-transformation screens identify mediators of oncogenic transformation as novel therapeutic targets for pediatric brain tumors' at our Journal Meeting #cancer Register: biologists.com/meetings/dmm... Early-bird deadline: 19 June 2026

Weekend read: head to @prelights.bsky.social website and read a preprint about Sun2 role in mechanosensing-driven extracellular matrix production and lung fibrosis, chosen by Beth Chopak. Prelight: bit.ly/4ucTbgj Preprint: doi.org/10.64898/202...

For anyone with an interest in (embryonic) stem cells, developmental biology and neuroscience....A short short for you

Progressive myoclonus epilepsy type 1 involves upregulated immune‑response genes, reduced oxidative phosphorylation, and disrupted lysosomal function (with key lysosomal genes activated and those required for acidification suppressed). Alina Malyutina, Tarja Joensuu & co doi.org/10.1242/dmm....

preLight highlighting how complex diseases such as multiple sclerosis require multidisciplinary approaches. prelights.biologists.com/highlights/g...

Delilah Hendriks @delilahhendriks.bsky.social is speaking on 'Advanced human organoid models to unravel early events of tumorigenesis' at our Journal Meeting this October #DMM2026cancer Register to attend: biologists.com/meetings/dmm... Early-bird deadline: 19 June 2026

Night owl or morning lark — it’s more than hearsay. In our April Issue Review, Siyu Chen and David Ray outline the evidence linking circadian rhythms to chronic inflammatory diseases and explore how this connection could be leveraged to improve treatment. doi.org/10.1242/dmm....

To mark #BrainTumorAwarenessMonth, we share our subject collection featuring research to accelerate translation into therapeutics tinyurl.com/4xjczsp8. Why not join us at our 'Innovative ‘Preclinical Models for Pediatric Cancer Research’ meeting tinyurl.com/yc2jra4k

Researchers analysed the extracellular RET structure, mapping 77 positions linked to Hirschsprung’s disease or multiple endocrine neoplasia type 2, and predicting how mutations across all 594 extracellular residues might alter RET structure. Fassler Bakhman, Kosloff & co doi.org/10.1242/dmm....

With new regulations taking effect, the question of which models best capture human disease is becoming increasingly urgent. In our April Editorial, we discuss why in vivo disease models remain essential, and our editors outline what in vitro systems can and cannot achieve. doi.org/10.1242/dmm....

Michael Underhill is speaking on 'Modelling synovial sarcoma in the mouse – insights into a potential cell of origin and tumorigenic trajectories' at our Journal Meeting this October #DMM2026cancer Register to attend: biologists.com/meetings/dmm... Early-bird deadline: 19 June 2026

Weekend read: head to @prelights.bsky.social website and read a preprint about changes in gut microbiome over the course of multiple sclerosis, chosen by Carole Djagang, Nour HAROUN, Phalica Georges and uMontreal Neuro preLighters. Prelight: bit.ly/4tFP63g Preprint: doi.org/10.64898/202...

Join researchers working on #PediatricCancer at our Meeting this October at Nationwide Children’s Hospital, USA. Organisers: James Amatruda, Pratiti (Mimi) Bandopadhayay, Ana Banito & Elaine Mardis Register at bit.ly/3OCi1q9 Early-bird deadline: 19 June 2026

Ana Banito is speaking on 'Somatic gene delivery for flexible in vivo modeling of pediatric sarcoma' at our Journal Meeting this October #DMM2026cancer Register to attend: biologists.com/meetings/dmm... Early-bird deadline: 19 June 2026

Introducing our last set of invited speakers at #ZDM19! Please join Chris Hall, James McGinty & Ben Shih-Lei Lai & the rest of the #ZDMS community in Oxford 🐟 We hope to see you there! Don't forget to submit an abstract! Deadline ends Friday (15th) ⌛ To submit: www.zdmsociety.org/zdm19-abstra...

DMM congratulates Francesca Giulia Urso (centre), from reNEW, winner of the DMM-sponsored poster prize at the latest advances in Latest Advances in Stem Cell-Based Disease Modelling and Drug Screening symposium.

Bone‑marrow biopsies from severe aplastic anaemia patients showed increased nestin⁺ niches, supporting immune injury and maladaptive stromal remodelling as disease drivers and highlighting the role of the marrow microenvironment. Beerlage, Drexler, Tzankov & co doi.org/10.1242/dmm....

A study in mice suggests that the Chiari II brain malformation—common in children with open spina bifida, a neural tube defect where the spine and spinal canal fail to close properly—develops as a secondary consequence of the defect. Maryam Clark, Andrew Copp & co Article doi.org/10.1242/dmm....

Head to our community website thenode.biologists.com for a weekend read: Some cancer drugs disrupt taste by changing the cells inside taste buds bit.ly/4t4tfSN @the-node.bsky.social

A CRISPR‑engineered #MouseStrain with a disrupted Il1a nuclear localisation sequence helps to investigate how nuclear trafficking shapes #inflammatory and #antiviral responses. Christopher Hoyle, David Brough, Gloria Lopez-Castejon & co Full paper doi.org/10.1242/dmm....

Seven patient‑derived #xenograft models of invasive lobular #cancer were developed and validated, featuring common alterations in PIK3CA (57%), CDH1 (57%), and TP53 (57%). Jagmohan Hooda, Jennifer Atkinson, Adrian Lee & co Full paper doi.org/10.1242/dmm....

A #zebrafish study shows that ctsz mutations disrupt #macrophage polarisation and #regeneration, suggesting that Ctsz modulates the inflammatory response to #injury and shapes regenerative outcomes. Bastos, Loynes, Speirs, @elkslab.bsky.social, Braga & co Full article doi.org/10.1242/dmm....

A #zebrafish model of spinocerebellar #ataxia type 37 shows that embryonic expression of the AUUUC repeat RNA disrupts axonal and synaptic development, impairing neuronal circuits and leading to adult motor dysfunction. Ana Castro, José Bessa Isabel Silveira & co Full paper doi.org/10.1242/dmm....

We are delighted to support @cruk-si.bsky.social Beatson International Cancer Conference 2026 ‘From Tumour Genesis to Metastasis: an immune perspective’. Don't miss the 1 May registration deadline.

We are pleased to be a media partner for EMBL Conference: Unlocking the functional diversity of gut microbiomes #EMBLGutMicrobeFunction Abstract submission: 15 Sep 2026 Registration (On-site): 27 Oct 2026 Registration (Virtual): 1 Dec 2026 bit.ly/4bpZ6Yr @embl.org @events.embl.org

Check April preprint highlight by preLighter Hannah Pletcher: a study identifying 4,5‑DHHA as a potential biomarker for monitoring mitochondrial diseases affecting the respiratory chain. PreLights: bit.ly/4tJjKJY Preprint: doi.org/10.64898/202... @prelights.bsky.social

Have you seen Cancer Conference Hub - @helloeacr.bsky.social calendar of cancer research conferences? You can add your event too. See more at bit.ly/4u1L6LP #CancerResearch

Delighted to be supporting the BACR workshop on tumour microenvironment and 3D cancer modelling. And don’t miss the upcoming DMM journal meeting on paediatric cancer — full details are pinned on our profile.

To celebrate #WorldMalariaDay this Saturday, join us in revisiting our 2025 Special Issue on infectious diseases journals.biologists.com/dmm/issue/18/9. DMM is committed to supporting research that drives progress against infectious diseases.

Delighted to be supporting ZDM19 – don’t miss the abstract deadline!