Excited to present our work at the 2026 #ISEH Mini Symposium! “Beyond the Maturation Block: Oncofetal Reprogramming and Stem Cell Plasticity in Pediatric Leukemia” Join us on April 16 to discuss developmental programs in leukemia and beyond. iseh.org/Webinars-Eve...

Exciting study by @lenakutscher.bsky.social and @doctorpauln77.bsky.social on male bias in medulloblastoma: “testosterone and the XY genotype cooperate to increase the abundance of specific cerebellar progenitor populations” Elegant use of Four Core Genotypes mice + recapitulation in organoids

Here's the preprint!!

New preprint alert! I'm excited to share our latest preprint where we investigate the underlying developmental causes of the male bias in the pediatric brain tumor Group 3/4 medulloblastoma. www.biorxiv.org/content/10.6...

Go Roy!!!

We’re looking for a HiWi to join our team! In case you know any current BSc or MSc students, preferably in an early semester, please send them our way. No need for prior experience - we’ll teach the necessary skills! jobs.dkfz.de/en/jobs/1684...

interested in working on sex differences during development and in tumor initiation! come join our lab via the MSCA MasterClass

We’re looking for a HiWi to join our team! In case you know any current BSc or MSc students, preferably in an early semester, please send them our way. No need for prior experience - we’ll teach the necessary skills! jobs.dkfz.de/en/jobs/1684...

The next #ScienceatDKFZ event will take place on Thursday, 19 March 2026, at 4 pm. In addition to the keynote lecture by Sigrid Carlsson, there will be four 5-minute short talks by DKFZ junior scientists on recent highlight publications. 👉 dkfz.de/en/news/even...

Registration is open for @dmmjournal.bsky.social 2026 meeting 'Innovative Preclinical Models for Pediatric Cancer Research' organised by James Amatruda amatrudalab.bsky.social, Pratiti (Mimi) Bandopadhayay, bandolab.bsky.social, Ana Banito & Elaine Mardis. Find out more bit.ly/46r84Ca #DMM2026cancer

They figured out meander tail mouse has an Mysm1 mutation! I have been curious about this mouse since I got into the cerebellum field, as this mouse is the only model identified so far that has defects preferentially in the anterior cerebellum. very cool follow up!! www.biorxiv.org/content/10.6...

Ramsey Najm and I have a joint postdoc position advertised through the @hlsalliance.bsky.social Interinstitutional Postdoc call! Our project proposes to generate better posterior cerebellar organoids to improve fidelity of pediatric medulloblastoma models. www.health-life-sciences.de/opportunitie...

Esther Becker, Simone Mayer and @lenakutscher.bsky.social teamed up to summarise current approaches for generating #cerebellar #organoids and advocate for the establishment of rigorous quality control standards to ensure reproducible, high-quality research. Read doi.org/10.1242/dmm....

Excited to share our preprint on our new multi-omic atlas of human hindbrain development. Led by postdoc Piyush Joshi, in collaboration with @kaessmannlab.bsky.social and Pfister labs, our atlas represents the first comprehensive view of human hindbrain development. www.biorxiv.org/content/10.6...

Some friends and I wrote a review with @biologists.bsky.social !! Together with Esther Becker and Simone Mayer, we explore the state of the cerebellum organoid field and offer practical guidance on getting this model system started in your own lab. journals.biologists.com/dmm/article/...

From my work on gerrymandering, I know that New Jersey politicians play dirty. Now my campaign faces its first test. To beat their petty games, I need at least 1,000 signatures from Democrats and unaffiliated voters in the 12th District. It's cold work. To help, sign up at SamForNJ.org - or DM me!

News from central Jersey: I'm running to represent New Jersey's 12th Congressional District. By entering the fray, I hope to bring ideas of repairing our frayed republic. Not only to defend it in 2026, but to build something stronger, for generations to come! samwang.substack.com/p/entering-t...

I've started my own lab 🎉 PhD/postdoc positions available - reach out if curious about cerebellum evo-devo and autism spectrum disorders. We’re based at Uni Tartu, Institute of Genomics (home to Estonian Biobank), and funded by @simonsfoundation.org @embo.org, and the Estonian Research Council.

Today I made a small but momentous start to work in 2026 by changing a single number. I renamed the file “Papers to write and submit in 2025” to “Papers to write and submit in 2026”. Stay tuned for more file updates on 1st January 2027.

I love this live version of the new @themountaingoats.bsky.social song. 🎶"There's always a clock ticking somewhere."🎶 youtu.be/pv53gRqjvxY?...

This entire weekend

The @dkfz.bsky.social PhD Program is open, and the Mall Lab is recruiting PhD students. 1: in vivo and organoid models to study and treat autism associated disorders. 2: cancer cell plasticity in brain tumors using single cell genomics and perturbation screens. Apply now: www.dkfz.de/en/career/in...

This will be a very exciting meeting! Looking forward to see you there Please spread the word

Olya Yarychkivska of @rockefeller.edu will kick off the #SDBPostdocSeminar with her talk "Myelin regulatory factor 1, identified by single cell transcriptomics, primes a migrating cell for non-apoptotic cell death" Image: Linker cell at the tail of a C. elegans male

Emmy Noether grant for DKFZ researcher Jens Puschhof.👏 With this grant, he aims to decipher the role certain intestinal bacteria play in the earliest stages of colon cancer development and how this process can be halted. t1p.de/aoeve @jenspuschhof.bsky.social

Paracetamol remains an important option to treat pain or fever in pregnant women. Following rigorous assessment of the available scientific data, we find no evidence that taking paracetamol during pregnancy causes autism in children. Read more 👉 www.ema.europa.eu/en/news/use-...

I am more than thrilled to announce that I will be starting my own lab at the Neuroscience Department at MUSC in November 2025! We will be studying the origin of pediatric brain cancers through the lens of brain development! My lab is hiring see here: cschmidtlab.xn--com-gr63bea

Like our sister journals, you can also submit an additional language abstract at @dev-journal.bsky.social and we cater for non-Western characters for author names. Did you know Development also facilitates retrospective author name changes?

🧠 Position still opened! Don't hesitate to apply if you want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders!

The mid-decade redistricting wars are unending. I'll be on CNN with Jake Tapper to talk about what we know and what it means. Is democracy dead? Is there hope? What can citizens do? This Wednesday August 13, sometime around 5:00-7:00pm Eastern. Precise time when I know it.

While I’m a big fan of new technologies that help us study human biology…there’s still no replacement for animal research! See my article in Gen News. www.genengnews.com/topics/trans...

i love my job #fluorescencethursday

We’re hiring! Come join our group at the DKFZ in Heidelberg. We’re seeking a MSc or PhD level bioinformatician who enjoys working in a team! Would be grateful for you to share with your networks. jobs.dkfz.de/en/jobs/1678...

Serious FOMO that I can't attend #Worm25

Did the miss the Cerebellum Development and Disease conference last year? Never fear, as we wrote up a conference report! link.springer.com/article/10.1...

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages. ki.se/en/about-ki/...

Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target

In response to someone in our running WhatsApp saying they were the slowest in the group, somebody replied, “Comparison is the thief of joy…” I’m going to think about that for the rest of the day

There’s been some “advice” coming from some quarters for scientists not to focus on DEI-related funding cuts. I wholly reject this concept. Cutting programs designed to reduce science and healthcare disparities is as detrimental to science as anything else, both morally and functionally.

Big congrats to our longtime collaborators in the Stefan Pfister and @lenakutscher.bsky.social labs — large-scale chromosomal changes as early tumour-initiating events in Group 3/4 medulloblastoma!

new out in Nature www.nature.com/articles/s41...

important reminder for people getting into arguments with people who are wrong in my mentions

Yes. This is an absolute crisis—and not a subtle one. Thread:

MSK's Dr. Alexandra Joyner is hanging up her lab coat following an illustrious 40-plus-year career. When asked what advice she has for new scientists, she shares: "You have to decide: Why are you going into this career? And then you have to stay true to that." Learn more about her legacy & impact ⬇️

Deadline extended! 🌟 Join us at the Neurogenomics Conference! 🧠 Dive into cutting-edge research on neurodevelopment, brain evolution, neurodegeneration, and more. Submit your abstract & register by 14 April 👉 humantechnopole.it/en/trainings...

"we have been watching with growing concern policy changes in the US...The scale of disruption to science is unprecedented...We are concerned with policies that threaten censorship & removal of public data...To our colleagues in the US, we stand with you" journals.biologists.com/jcs/article/...

🔬✨ Be a part of #EANO2025! Submit your abstract now and present your research as an oral presentation or poster at the big event in Prague. We can't wait to see your contributions! Click here for more information: www.eano.eu/eano2025/abs... #NeuroOncology #neurosurgery #cancernurse

Working with an interdisciplinary team, we have developed a website to communicate how the White House's proposed cuts to health research would cause losses of $16B and 68,500 jobs. Find out how your community may be impacted. Explore more at SCIMaP: scienceimpacts.org a 🧵