Rockefeller scientists are unpacking the basic biology of the microscopic invaders that cause vector-borne diseases—and our own immune responses to them—with the hope of developing the necessary tools to ward them off. Learn more in #SeekMagazine: seek.rockefeller.edu/taming-mosqu...

Today and every day, we celebrate women scientists on our campus and around the world who are pushing boundaries, asking bold questions, and solving real-world problems. Happy #InternationalDayOfWomenInScience!

Renowned astronomer Chris Impey of @stewardobservatory.bsky.social has been named the 2026 recipient of Rockefeller’s prestigious science writing award, the Lewis Thomas Prize! Register for the ceremony on March 9 here:

Rockefeller's Alipasha Vaziri has developed some of the most powerful tools to observe brain-wide neural activity at the cellular scale in real time. We spoke to Vaziri about where this technology can ultimately lead us and more in this #SeekMagazine Q&A: https://bit.ly/4rznY5g

The Vertebrate Genomes Project, led by Rockefeller's @erichjarvis.bsky.social, is preserving the genetic information of endangered species with help from @newsfromgoogle.bsky.social's AI tools:

This #WorldCancerDay we're highlighting work from Rockefeller's Kivanc Birsoy. In this Q&A, he shares why he's hopeful that targeting cancer cells' nutrients will yield a new, effective approach to fighting cancer: https://bit.ly/4qRBIse

In 1940, Karl Landsteiner made a discovery in his lab at Rockefeller with huge implications: his research revealed the Rh factor—an antigen on the surface of red blood cells that can cause severe complications during pregnancy. #125YearsofRockefeller

In this Q&A with Rockefeller's Paul Cohen and @maschakoenen.bsky.social, they discuss their recent study that uncovered the mechanism—and the enzyme—that explains how fat can stiffen blood vessels and drive blood pressure upward: https://bit.ly/49Xe1cc

A study in @cellpress.bsky.social from Shixin Liu and Michael O’Donnell finds that a protein once thought to simply help load a factor necessary for the copying of DNA actually plays a key role in ensuring fast and reliable replication: https://bit.ly/4qOodK1

Rockefeller's Vertebrate Genome Laboratory (vertebrategenomes.bsky.social) has received support from Google.org for #AI science research. The funding will help the VGL accelerate the production and analysis of high-quality genomes across Earth’s #biodiversity.

A study from @casanovalab.bsky.social shows that autoantibodies in a small subset of the population can allow weakened vaccine viruses to escape control, explaining some adverse events tied to one kind of Chikungunya vaccine, which is no longer available in the U.S.

In 1943, Rockefeller’s Oswald Avery, Colin MacLeod, and Maclyn McCarty demonstrated that #DNA carries an organism’s genetic information. Their discovery launched a scientific revolution that’s placed genetics at the core of modern biomedical science. #125YearsOfRockefeller

A recent study from the #FreiwaldLab found that emotion-driven facial expressions activate the same cortical pathways as do voluntary movements, such as chewing. Learn more in this piece from @thetransmitter.bsky.social:

New work from Gaby Maimon in @cellpress.bsky.social uncovers an electrical trick that allows neurons to compute direction efficiently by juggling multiple signaling mechanisms. The study advances our understanding of how brains compute at a fundamental level. 🔗: https://bit.ly/4r0k1pX

Rockefeller's Paul Cohen helps explain what poor metabolic health is and how it can wreak havoc on the body in this piece from @nytimes.com:

Emil C. Gotschlich, born #OTD, was recognized with a #LaskerAward for his development of a polysaccharide vaccine to prevent #meningitis. 🧪 The Rockefeller University https://ow.ly/bxE750Umu7T https://ow.ly/tS1B50Umu7R

A study in @science.org from Paul Cohen's lab, led by @maschakoenen.bsky.social, demonstrates how beige fat directly influences blood pressure. The findings offer a new target for treating vascular disease and could lead to more precise therapies for hypertension: https://bit.ly/4pK0hGh

Rockefeller's Jean-Laurent Casanova is featured in this @nature.com piece by @dianakwon.bsky.social on how genetic mutations can weaken the immune system and make people more vulnerable to certain infections: www.nature.com/articles/d41...

For decades, scientists have designed drugs to slow down or block enzymes, but Tarun Kapoor wondered if tackling some diseases requires the opposite approach. We spoke with Kapoor about why speeding up an enzyme is so difficult, and how his team is cracking this problem. See the full Q&A here:

Congratulations to Rockefeller's Svetlana Mojsov, who has been named the 2026 recipient of the King Faisal Prize in Medicine! She is recognized for her groundbreaking work on GLP-1, research that has transformed the treatment of diabetes and obesity.

A new study suggests that primate facial expressions may not just be reflex

A new study in @science.org from Rockefeller's Winrich Freiwald demonstrates how neural circuits in the brain and muscles of the face work together to respond physically to social cues, findings that may lead to improved brain-machine interfaces that help people with brain injuries communicate.

We are saddened to share that Konstantin Goulianos, a member of the Rockefeller community since 1971, has passed away. Goulianos was a renowned particle physicist who contributed to the discovery of fundamental building blocks of matter.

The late James Hudspeth achieved a groundbreaking technological advancement before his death: the ability to keep a mammalian cochlea alive outside the body for the first time. A new piece in Popular Mechanics discusses his work:

Bittar, Nussenzweig et al. @rockefeller.edu describe expanded clones of authentic CD4+ T cell carrying intact latent HIV-1 proviruses derived from people living with #HIV. Their transcriptome mirrors their primary cells of origin. rupress.org/jem/article/...

Thanks for recapping the most intriguing #RockefellerScience stories of 2025 with us, Happy New Year! 👩🏽‍🔬 🥂 🦠 🎉 🧬 See the full 2025 #YearInReview here: https://bit.ly/44LtGrW

Scientists in the @alushinlab.bsky.social figured out how cells build a structure that lets them migrate. Unpacking these “finger-like” protein bundles that protrude from cells may lead to novel treatments for #metastasis. #RockefellerScience #YearInReview 🔗: https://bit.ly/3PKErmA

A study from @danmucida.bsky.social and @victora.bsky.social showed how immune cells in the gut distinguish between food and harmful pathogens, shedding light on the origins of #foodallergies. #RockefellerScience #YearInReview 🔗: https://bit.ly/4hyS18b

A study from the #RutaLab explained how the fruit fly brain coordinates courtship and aggressive competition—a framework which could help scientists understand how the human brain balances cooperation and competition. #RockefellerScience #YearInReview 🔗: https://bit.ly/4gI7phV

A study from Erich Jarvis and @darnelr.bsky.social found that a single protein variant found only in humans may have helped shape the emergence of spoken language. When put in mice, the variant altered their vocalizations. #RockefellerScience #YearInReview 🔗: https://bit.ly/3Yfdcoh

A study from the #FriedmanLab identified a neural mechanism involved in leptin resistance, a factor contributing to #obesity. Crucially, they also found a way to reverse it in mice using a well-known drug. #RockefellerScience #YearInReview 🔗: https://bit.ly/3MV0WqC

Clinical trials based on work from the Nussenzweig lab showed that two broadly neutralizing antibodies can keep #HIV suppressed for months. The data suggest that the antibodies may even diminish the viral reservoir itself. #RockefellerScience #YearInReview 🔗: https://bit.ly/4pkY045

A new method from @hirofunabiki.bsky.social dramatically improved cryo-EM’s imaging capabilities, enabling visualization of molecules that are very rare, very small, or hard to produce naturally—including some viruses. #RockefellerScience #YearInReview 🔗: https://bit.ly/4awR4gv

The #StricklandLab discovered that amyloid-beta (Aβ) oligomers and the vascular protein fibrinogen may, when forming a complex, contribute to Alzheimer's disease. #RockefellerScience #YearInReview 🔗: https://bit.ly/44Eh31R

The #StellerLab found that boosting PI31 can prevent neuronal degeneration, restore synaptic function, and significantly extend lifespan in fly and mouse models of rare genetic disorders similar to Parkinson’s. #RockefellerScience #YearInReview 🔗: https://bit.ly/3MOlmSc

Research from the Fuchs lab showed that low levels of the amino acid serine trigger a process that turns hair follicle stem cells into skin repair specialists—and that diet may have a role to play. #RockefellerScience #YearInReview 🔗: https://bit.ly/4jfd9CA

Rockefeller's Li Zhao spent nearly a decade cataloguing evolutionarily young genes. This year, her lab demonstrated how these new genes are regulated and expressed. #RockefellerScience #YearInReview 🔗: https://bit.ly/4jdvwb8

Treatments for autoimmune diseases have big shortcomings, including high cost and supply shortages. A alternative developed this year from the #RavetchLab achieves the same effectiveness at a fraction of the dose. #RockefellerScience #YearInReview 🔗: https://bit.ly/3HFdsbs

A study from the Birsoy lab showed that the antioxidant glutathione, when operating inside mitochondria, is a key factor enabling tumors to spread from the breast to the lung. #RockefellerScience #YearInReview 🔗: https://bit.ly/44GfOPG

Shortly before his death this year, James Hudspeth achieved a groundbreaking technological advancement: the ability to keep a tiny sliver of the cochlea alive and functional outside of the body for the first time. #RockefellerScience #YearInReview 🔗: https://bit.ly/49oaOlo

The #BradyLab identified compounds that appear effective against drug-resistant bacteria using a new technique that could uncover many more antibiotics, as well as help illuminate a previously hidden microbial world. #RockefellerScience #YearInReview 🔗: https://bit.ly/4sjhV6j

The first detailed look at how mosquitoes mate from the Vosshall lab reversed the assumption that male mosquitoes control the process, finding that a subtle female behavior dictates if mating will take place or not. #RockefellerScience #YearInReview 🔗: https://bit.ly/4huwEpL

Neuroscientists have long posited that #memory functions like an on/off switch—either your brain remembers something or it doesn’t. The #RajasethupathyLab discovered that the truth is more complicated. #RockefellerScience #YearInReview 🔗: https://bit.ly/3MoSsrj

The #WalzLab revealed key details about the T cell receptor, which is essential to T cell immunotherapies. The findings could expand T cell therapies, bringing their benefits to a broader group of #cancer patients. #RockefellerScience #YearInReview 🔗: https://bit.ly/3L0r3vK

Winter break is upon us! Stay tuned as we count down the most intriguing #RockefellerScience stories of 2025. #YearInReview

Scientific publishing has a bias against negative results and that hurts science, says Tim Fessenden, editor of @lsajournal.org, a publication of @rupress.org. Here’s how journal editors can help.

The #RajasethupathyLab has identified a gene that improves attention, findings in @natneuro.nature.com#RajasethupathyLabthat may lead to a novel therapeutic approach to calming the mind. The study has implications for treating #ADHD as well as autism and schizophrenia.

A study from the #TarakhovskyLab reveals how diapaused embryonic stem cells maintain their ability to become any cell type. This newly discovered mechanism may explain how immune cells—and even #cancer cells—can survive long periods of metabolic stress.

In @natureportfolio.nature.com: Researchers, including Rockefeller's own Gabriel Victora (@victora.bsky.social), are striving to understand the impact a phenomenon known as original antigenic sin has on immunity to the virus that causes the flu.

Researchers in the #RavetchLab have developed a potential replacement for treating #autoimmunedisease that’s significantly more potent than intravenous immunoglobulin therapy. Learn more in this Q&A with Jeffrey Ravetch and first author Andrew Jones: https://bit.ly/3KTnzLy