A @natchembio.nature.com study from the #RoederLab identifies a molecular switch in breast cancer cells that reprograms the genetic production line towards tumor growth and stress resistance in stressful conditions, providing a potential new target for cancer therapies.

This #WorldDiabetesDay we're highlighting Rockefeller's own Svetlana Mojsov, whose work on GLP-1 led to a new class drugs for type 2 diabetes as well as the treatment of obesity. Check out this interactive timeline to learn more: https://bit.ly/47YGDPQ

Treatments for autoimmune conditions are either difficult to administer or broadly suppress patients’ immune systems—creating a huge unmet need for better therapies. Nuvig Therapeutics, cofounded and advised by Rockefeller's Jeff Ravetch, aims to meet it.

According to the 2025 CWTS Leiden Ranking Open edition of over 2,800 universities from 120 countries, Rockefeller has the highest percentage of most frequently cited scientific publications. Way to go, Rockefeller! 👏 👏 👏

Researchers in the Vosshall lab have discovered the first evidence of what happens when a female mosquito chooses to mate for the one and only time in her life. We spoke to @leslievosshall.bsky.social and @leahhouri.bsky.social about their unexpected findings. See the full Q&A:

Happy to see our recent work on SLC25A45 featured on the cover of @cp-cellmetabolism.bsky.social . Huge thanks to @yuyangliu.bsky.social for the design! @KivancBirsoy @rockefeller.edu

Current treatments for autoimmune diseases have significant shortcomings, including high cost and supply shortages. A new alternative from the #RavetchLab achieves the same effectiveness when tested in mice at a fraction of the dose. @science.org#RavetchLab

In today's episode, Neuroscientist Erich Jarvis explores the connections between birdsong and speech: www.birdnote.org/podcasts/bir... @rockefeller.edu

The #TarakhovskyLab, as part of an international team of scientists, has identified a new molecular pathway that shifts microglia into a protective state. The findings may lead to Alzheimer's therapies that can reprogram the brain’s own immune defenses.

It turns out female mosquitoes are in charge during sex. A study found they give a subtle signal when they accept a mate, a overturing decades of assumptions about mosquito behavior. I wrote about this fascinating work by @leahhouri.bsky.social, @leslievosshall.bsky.social et al for @nature.com:

Good luck to Rockefeller's Clare Cahir, Heloise Carion, Erika Layfield, Julia Losner, Dan Oh, Ethan Seltzer, Taylor Wallace, and all other runners in the NYC Marathon this Sunday! 🏃🏽 🏃🏽‍♀️ 🏃🏽‍♂️

A global effort, led by @leslievosshall.bsky.social and @nadavshai.bsky.social, just made the most dangerous animal in the world a lot easier to study—and perhaps defeat one day. Learn more about the first head-to-toe cellular atlas of the mosquito, published in @cellpress.bsky.social, below.

In @nature.com: Using AI and other cutting-edge techniques, the Klinge lab has captured the first near-continuous "molecular movie" of ribosome formation—revealing, frame by frame, how cells build the protein factories that make life possible. More here: https://bit.ly/3LbHTaF

The first detailed look at how mosquitoes mate from @leslievosshall.bsky.social's lab reverses the assumption that male mosquitoes control the process, finding that a subtle female behavior dictates whether mating will take place or not. @currentbiology.bsky.social More here: https://bit.ly/4huwEpL

Congratulations to Rockefeller's Steve Bonilla, who has been named an @hhmi.org Freeman Hrabowski Scholar! Bonilla's lab is pursuing insights into the fundamental rules of RNA folding, structure, and dynamic function.

Greg Alushin (@alushinlab.bsky.social) is decoding how the body’s building blocks sense and respond to force, with implications for everything from cancer to developmental disorders. In this Q&A, he discusses where his work on the cytoskeleton could lead us:

Have you signed up for our science newsletter yet? Subscribe now to stay on top of the latest discoveries taking place right here at Rockefeller, delivered monthly to your inbox: https://bit.ly/34Ez7YI

A new @pnas.org study from Michael Rout, working with a team led by the Hebrew University of Jerusalem, solves the long-standing mystery of how NPCs make split-second decisions about which molecules to allow to pass through their molecular gates: bit.ly/4hleGGd

Rockefeller's Jeff Friedman has won the 2025 Albany Medical Center Prize, one of the nation’s most prestigious prizes in biomedicine. Friedman is recognized for his discovery of leptin, which established a biological basis for obesity. Congrats, Jeff!

Don't miss this piece in @thetransmitter.bsky.social by @vcallier.bsky.social on @danielkronauer.bsky.social's latest work! His lab discovered that a protective screen of spurious transcriptional activity enables each olfactory neuron to express exactly one out of hundreds of olfactory receptors.

Svetlana Mojsov has won the 2025 Kimberly Prize in Biochemistry from Northwestern University Feinberg School of Medicine! She is recognized for her discovery of GLP-1, a gut hormone central to insulin regulation and now the basis of widely used diabetes and weight-loss treatments. Congratulations!

Congrats to @veenapadmanaban.bsky.social of the @sohailtavazoie.bsky.social lab, who was honored at the Blavatnik Awards Ceremony this week! Veena's work established neurons as novel drivers of breast cancer metastasis and uncovered actionable therapeutic targets. Learn more below:

A study from the @danielkronauer.bsky.social lab has revealed a new form of olfaction gene regulation that may be broadly shared across insect species—opening up a new window into studying connections between genes and social behaviors. Read a Q&A with the scientists:

By boosting a single protein, PI31, the Steller lab restored a cleanup system in the brain—potentially pointing toward a new strategy for treating Alzheimer's and related disorders. Read a Q&A with Steller about this work below:

Happy Science Saturday! Rockefeller's annual science festival for kids that connects world-class scientists with kids from across the city was a smashing success 🧪 🔬 🧬

Congrats to the 2025 Lasker~DeBakey Clinical Medical Research Award winners, recognized for their roles in developing a novel treatment for cystic fibrosis. Remarks from Rockefeller president Rick Lifton detail the remarkable history and impact of this discovery.

Last week, developmental biologist Maria Jasin of @mskcancercenter.bsky.social was awarded the 2025 Pearl Meister Greengard Prize, the preeminent international award recognizing outstanding women scientists. Congratulations! #WomenInStem

🎶 The Peggy Rockefeller Concert Series opens the 2025–26 season with the acclaimed Beo String Quartet joined by pianist Ilya Yakushev on September 30. Learn more about the Peggy Rockefeller Concerts and buy tickets below.

A new study from the #BradyLab marks a breakthrough in accessing the so-called microbial dark matter that lurks everywhere on our planet. We asked Sean Brady and lead author Jan Burian how the findings may kickstart a new era of discovery in microbiology.

The first day of fall has arrived, and campus will soon be glowing with rich autumn colors. From the riverfront to the tree-lined paths, the changing foliage brings a new season of beauty to Rockefeller.

This #PostdocAppreciationWeek, we celebrate postdocs at Rockefeller and beyond! In these short Q&As, we invite you to meet a few of them, hear about their work, and get a glimpse of the interests and experiences that inspire them outside the lab.

A new study in ants from @danielkronauer.bsky.social reveals a previously unknown mechanism that ensures that each olfactory neuron expresses only one odorant receptor, with broad implications for the study of gene regulation. #RockefellerScience https://bit.ly/4pwPFLY

Remembering Jim Hudspeth, who passed away last month.

As body weight fluctuates, fat cells—collectively known as adipose tissue—wax and wane. Mascha Koenen, of the #CohenLab, is studying why this oscillation wreaks havoc on the body’s metabolism, especially in the case of yo-yo dieting. Learn more in Seek: https://bit.ly/469yMPS

A study from the #StellerLab in @pnas.org finds that boosting PI31 can prevent neuronal degeneration, restore synaptic function, and significantly extend lifespan in fly and mouse models of rare genetic disorders similar to Parkinson’s. #RockefellerScience

TONIGHT ON CAMPUS! Don't miss Maria Jasin accept the Pearl Meister Greengard Prize. Her fundamental research on repair of damaged DNA in cells has transformed our understanding of cancers linked to inherited gene mutations. #WomenInStem Register here: https://www.rockefeller.edu/greengard-prize/

Congratulations to all, especially Rockefeller's @veenapadmanaban.bsky.social, a research associate in @sohailtavazoie.bsky.social's lab, and Maria Cecilia Campos Canesso, formerly a postdoc in @danmucida.bsky.social and @victora.bsky.social’s labs. A very well-deserved recognition!

Don't miss this profile of Rockefeller's Li Zhao in The Scientist by @lauraatran.bsky.social! Zhao's work explores the unexpected emergence of de novo genes, shedding light on their crucial function in adaptation and evolutionary progress.

Now out in @natbiotech.nature.com: Newly identified compounds from the #BradyLab appear effective against drug-resistant bacteria. The technique used to reveal them could uncover many more antibiotics, as well as help illuminate a previously hidden microbial world. #RockefellerScience

Maria Jasin, whose fundamental research on repair of damaged DNA in cells has transformed our understanding of cancers linked to inherited gene mutations, has been selected as the 2025 recipient of the Pearl Meister Greengard Prize. Congratulations! #WomenInScience

The latest issue of our research magazine Seek is out! Explore groundbreaking research on infectious disease, how AI is supercharging biomedical sciences, technology that’s changing how scientists view the brain, and more. Read the full issue here: https://t.co/OtuOg3qQUa

Shortly before his death last month, James Hudspeth and his team achieved a groundbreaking technological advancement: the ability to keep a tiny sliver of the cochlea alive and functional outside of the body for the first time. #RockefellerScience

Dana Orange’s research on rheumatoid arthritis aims to help predict flares, provide precise drug targets, and enable interventions that block symptoms before they begin. Learn more in this Q&A:

Applications are now open for September 2026 enrollment in The David Rockefeller Graduate Program in Bioscience. Join a vibrant community of scientists pushing the boundaries of discovery. Learn more here: https://www.rockefeller.edu/education-and-training/graduate-program-in-bioscience/

🎶 The Peggy Rockefeller Concert Series returns for the 2025–26 season! 🎶 Join us throughout the season for inspiring performances right here on campus. Discover the full season and reserve your tickets here:

Long dismissed as impossible, nerve regrowth is offering new hope for injuries and neurodegeneration. In this @sciam.bsky.social piece, learn how Rockefeller's Fernando Nottebohm contributed to the evidence that neurons in the body and brain can repair themselves.

A new journal club is offering students, postdocs, early career researchers, and the entire Rockefeller community the chance to break bread with some of Rockefeller’s prominent researchers—and learn about the process behind their seminal breakthroughs.

Applications for faculty positions at Rockefeller are now open! We are seeking exceptional, creative scientists to join our faculty. Learn more below:

We are deeply saddened to share that our friend and colleague Jim Hudspeth passed away on Saturday. We will remember and continue to be inspired by Jim’s integrity, his humility, and his unwavering commitment to discovery.

A new study from the #BirsoyLab shows that the antioxidant glutathione, when operating inside mitochondria, is a key factor enabling tumors to spread from the breast to the lung. #RockefellerScience