@isscr.org award nominations are closing next week! ⌛ Help recognize and celebrate contributions in the fields of stem cell biology and translational medicine. Submit your nomination: https://bit.ly/4gJ5v27

Tsinghua University researchers generated gastroids to model early stomach development. Read the Nature paper: https://go.nature.com/4m8JGdv Listen to the discussion on our latest episode: https://bit.ly/46rosSb

A team at the University of Hong Kong used #CRISPR screening in gastric tumor #organoids to identify cancer targets. 🎯 Article: https://bit.ly/46ndPRp Episode with discussion: https://bit.ly/3VinHWx

This week: Researchers at Roche developed and characterized human brain #organoids to study neuronal myelination and assess the remyelination potential of drugs. 📎: https://bit.ly/4nFWLfv 🎧: https://bit.ly/46rosSb

How do stem cells age in space? 🛸 Jessica Pham and a team in Dr. Cat Jamieson's lab at UC San Diego sent HSPCs to the International Space Station and found accelerated hallmarks of #aging. Article: https://bit.ly/3HT7Sm5 Discussion: https://bit.ly/46rosSb

We have a new episode out! Dr. Lars Velten from the Centre for Genomic Regulation talks about his research on #LineageTracing and #hematopoiesis: https://bit.ly/4gsvo5X

Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery www.nature.com/articles/s41...

Join us next week for a conversation with Dr. Lars Velten from the @crg.eu ! 🩸 Check out his team's Nature paper on the dynamics of blood aging: https://go.nature.com/4pwXbqi

Check out this new #xenotransplation study in @natmed.nature.com#xenotransplation Genetically engineered pig lungs were transplanted into a brain-dead human recipient, where they were functional for 9 days. 📎- https://go.nature.com/3V31jAe 🎧 - https://bit.ly/4gdEByY

Researchers at Shandong University targeted extracellular matrix-producing cells with #CART therapy to improve kidney fibrosis in #ChronicKidneyDisease. Cell Stem Cell paper: https://bit.ly/45Lv1zY 🗨️: https://bit.ly/4gdEByY

New from the @tesarlab.bsky.social ! Dr. Kevin Allan and Jesse Zhan identified SOX6 as a key regulator of #oligodendrocyte maturation. 🧦 Read the Cell article: https://bit.ly/41ABMCf Listen to the discussion: https://bit.ly/3JWWpT9

Drs. @dbenzinger.bsky.social‬ and @jamesbriscoe.bsky.social at the @crick.ac.uk established an #optogenetic system for the precise spatiotemporal control in vitro of Sonic hedgehog morphogen production. 🦔 📄 - https://bit.ly/3Vxf0rf 🎙️ - https://bit.ly/3JWWpT9

We have a new episode out with Dr. @alice.soragnilab.com from UCLA! Learn about her research on patient-derived #organoids to study #RareDiseases: https://bit.ly/47v66C5

Learn more about Dr. Soragni's patient-derived #organoids in our next episode!

💓 Researchers in the @josesilvalab.bsky.social used #SmallMolecules to convert mouse ESCs into embryo founder cells, which generated a complete embryo model! Article: bit.ly/4orpbLb Episode with discussion: bit.ly/4oTURt2

We have a new episode out with Dr. Zhongwei Li from @stemcell.keck.usc.edu! Learn about his work on #kidney development and disease: https://bit.ly/4oM6t11

Implement the ISSCR Standards for Human Stem Cell Use in Research with confidence! We’ve partnered with @isscr.org to create a free, on-demand course to help researchers align with best practices and incorporate ISSCR Standards into their work. 🔗 Read more: bit.ly/4mZqqjx

A new @natmed.nature.com study from a team at Fourth Military Medical University uses #RNAseq to explore the dynamics of immune cells after liver #xenotransplantation. Paper: go.nature.com/3IX3EtR Episode: bit.ly/4ooU5Ut

Drs. Per-Ola Carlsson, Sonja Schrepfer, & a team at Sana Biotechnology transplanted genetically modified #allogeneic donor #islets into a man with long-standing #Type1Diabetes. Read the results in @nejm.org: bit.ly/4lmcajr Listen to the discussion: bit.ly/4ooU5Ut

1/n Fun journey continues: Our new @cp-cellstemcell.bsky.social paper out on how the Inherent & Dormant Plasticity of Mouse Naive PSCs can be "Exaggerated" to Directly form ~E8.5 Transgene-Free (TF) Mouse SEMs & WITHOUT inducing 8-16-Morula-like "Embryo Founder Cells". www.cell.com/cell-stem-ce...

📢 What are your thoughts on the podcast? Let us know in this ten-minute survey and you’ll be entered to win a Bluetooth speaker! 📋 bit.ly/4eWSLEj

We have a new episode out now! Learn how Dr. Mark Hatley (@hatleylab.bsky.social) from @stjuderesearch.bsky.social is using #rhabdomyosarcoma to study the developmental origins of pediatric cancer: bit.ly/4ooU5Ut

Check out these liver #organoids from Dr. Takanori Takebe's lab! Dr. Norikazu Saiki and the team produced organoids capable of forming their own internal blood vessels and coagulation factors. Article: go.nature.com/44QbXPs Discussion: bit.ly/3IGfUP1

This week: the #metabolomics of HSPCs! A new @natcellbio.nature.com study from Drs. Marialena Lalioti, Mari Carmen Romero-Mulero, Joerg Buescher, and @ninacabezas.bsky.social identifies metabolic changes that occur with differentiation, aging, and #AML. 📝- go.nature.com/4kOZVLX 🎧- bit.ly/3IGfUP1

The other, other best part of meetings is sharing the science and fun with the next generation! Great representation from Sharma lab at #BCVS25. Thanks Maedeh, Jemima, and Sean for excellent posters on all things iPSCs, organoids, organ chips, and cardiotoxicity! 🫀

🐌💫 Snail embryos never looked so fabulous! Tubulin (white), phospho-histone H3 (pink), and F-Actin (cyan) light up this early stage like a cytoskeletal disco ball. Image from Clemens Cabernard & Adam von Barnau Sythoff 🪩🧬 #FluorescenceFriday

Drs. @simonmiao26.bsky.social, Nicole Pek, and Drs. Minzhe Guo and @mingxiagu.bsky.social's labs co-differentiated mesoderm and endoderm in the same spheroid to vascularize lung and intestinal #organoids! @cellpress.bsky.social article: bit.ly/3H1ar4V Discussion: bit.ly/3IGfUP1

Drs. @kylessmith.bsky.social, Yiran Li, and a team in @doctorpauln77.bsky.social's lab at @sjcenos.bsky.social analyzed previously published #scRNAseq data and found no evidence of transitional cerebellar progenitors. Read the article: go.nature.com/46iVgyl Listen to the discussion: bit.ly/3IGfUP1

🥳 We just released our 300th episode! Thank you to all of our listeners, whether you've joined us recently or been here since the beginning. Stream the 300th episode here, featuring special guest Dr. Jeanne Loring (@jfloring.bsky.social): bit.ly/44YrzjU

Our 300th episode just dropped! 🎉 🦏 Listen to stem cell legend Dr. Jeanne Loring (@jfloring.bsky.social) discuss her wide-ranging work, from endangered species preservation to #CellTherapy for Parkinson's. 🧠 📍 bit.ly/3IGfUP1

New from the ‪@meleromartinlab.bsky.social & Dr. Kai Wang's lab! Dr. Liyan Gong & her colleagues generated functional vascular #organoids via orthogonal activation of the transcription factors ETV2 and NKX3.1. @cp-cellstemcell.bsky.social paper: bit.ly/3HH9Hlx Episode: bit.ly/4nzLrCp

Our latest work is out today in @science.org: a self-organizing system that models organizer-driven patterning and commissural axon guidance in human neural development. Work led by Massimo Onesto with Neal Amin in the lab

Introducing digital embryos! Researchers at Southeast University Nanjing reconstructed full digital embryos at #SingleCell resolution during early #organogenesis. 📑 @cellcellpress.bsky.social: bit.ly/44EzzX0 🎧: bit.ly/4nzLrCp

My postdoc work at Treutlein lab and @graycamplab.bsky.social with @jasperjanssens.bsky.social is out in @science.org ! We screen for neuron subtypes using pro-neural TFs + morphogen combinations + scRNA-seq and profiled over 700,000 cells in 480 conditions. www.science.org/doi/10.1126/...

Load up your playlist with these 5 recent episodes of the @stemcellpodcast.com. 🎧🧵 ➡️ Ep. 299: “Spinal Cord Development” Featuring Dr. James Briscoe ➡️ Ep. 297: “Live at ISSCR 2025: Advancing Regenerative Medicine with CiPSCs” Featuring Drs. Hongkui Deng and Candice Liew

This patient-derived #organoid co-culture system models #LungCancer and reflects the #immunotherapy outcomes of corresponding patients! 🔖 @cp-cellstemcell.bsky.social: bit.ly/466pcO2 🎙️: bit.ly/4nzLrCp

Congratulations to Dr. @akanksha-jain.bsky.social, Gilles Gut, and the Treutlein Lab and @graycamplab.bsky.social on their work live imaging brain #organoid growth! @nature.com article: go.nature.com/4la2yZh Episode with discussion: bit.ly/4nzLrCp

We have a new episode out! Tune in to hear Dr. @jamesbriscoe.bsky.social from @crick.ac.uk discuss his research on the developmental dynamics of the #SpinalCord, and his position as Editor-In-Chief of @dev-journal.bsky.social. Listen now: bit.ly/4nzLrCp

How do organelles change over the course of a stem cell’s life? ADIs @cohenlaboratory.bsky.social, @assafzaritsky.bsky.social , and @mattersoflight.bsky.social are using ML and cell engineering to explore the #FrontierScience of stem cell differentiation. alleninstitute.org/division/fro...

🛰️ @arunsharmaphd.bsky.social was just interviewed on the International Space Station National Laboratory's podcast! Learn about his work sending cardiac stem cells to space, and how #microgravity can accelerate #biomanufacturing and #DrugDiscovery. 📍 Listen here: bit.ly/46hfAQw

Catch up with #ISSCR2025 delegates! Our 'On the Ground' episode is out now, and features discussions with delegates about their impressions of the meeting and the most memorable research presented. Listen now: bit.ly/45DFhL1

Honored and thrilled that my PhD work is selected as the Featured Image on Science Translational Medicine! We developed gold nanoclusters to cross the blood-brain barrier, accumulate in glioblastoma. science.org/doi/10.1126/... #STM #Glioblastoma #Nanomedicine #Intravitalimaging

We have a special episode out for you now, recorded live at #ISSCR2025! Drs. Hongkui Deng and Candice Liew share the story behind their groundbreaking study transplanting CiPSC-derived islets into a patient with #Type1Diabetes. Listen now: bit.ly/4n9c54K

Check out these liver #assembloids from the @merihuchlab.bsky.social! Drs. Anna Dowbaj and Aleksandra Sljukic generated mouse liver assembloids that model aspects of aspects of biliary liver fibrosis. 📝 go.nature.com/4e11KU9 🗨️ bit.ly/4kRfsMk

Drs. @oscarabilez.bsky.social, Huaxiao 'Adam' Yang, and a team in Dr. Joseph Wu's lab generated vascularized cardiac and hepatic #organoids! Read the @science.org paper: bit.ly/3FBuHtr Listen to the discussion: bit.ly/4kRfsMk

Looking for something to listen to on the way home from #ISSCR2025? Our final daily episode is out! Catch up on the research presented on the final day of the meeting. Listen now: bit.ly/407DHx8

Thank you to our attendees, speakers, sponsors, and exhibitors for making #ISSCR2025 a great success! We hope you will join us in Montréal in July 2026 for #ISSCR2026!

Thank you all for an incredible #ISSCR2025! Safe travels home and we'll see you in Montreal! ✈️

Thank you to everyone who joined us for our "On the Ground" #ISSCR2025 episode! Hear what they had to say when the episode airs on June 24th!

We're back with another #ISSCR2025 episode! Daylon and Arun discuss research on ex utero embryo culture, long-term brain #organoids, and sponge regeneration! 🧽 Check it out: bit.ly/4416YL6