Gladstone's Barbara Engelhardt will speak at the EPFL Latsis Symposium 2026, bringing together global leaders in single-cell biology, AI, computational modeling, and synthetic biology to explore the future of decoding and engineering cellular states.

A microscope at @gladstoneinst.bsky.social is on the search for new Parkinson's treatments. It designs its own experiments, runs thousands simultaneously on individual cells, learns from the results, and repeats-- without guidance from scientists. gladstone.org/news/how-ai-...

Gladstone scientists developed a new tool to trace how the brain clears “waste,” uncovering surprising new biology about how it keeps itself healthy. Listen to this story! 🎧

Antibiotic-resistant infections are a growing global threat. Gladstone has launched the Center for PhAIge Therapy, bringing together AI, engineering, and phage biology to develop new ways to fight drug-resistant bacteria.

Drug-resistant infections cause millions of deaths each year. Gladstone is tackling the challenge with the Center for PhAIge Therapy, combining AI, bioengineering, and phage research to develop next-generation treatments for antibiotic-resistant bacteria.

We know which soccer team we're rooting for ⚽

A team led by Jennifer Doudna developed an innovative chromatin-shredding technique shown to destroy cancer cells carrying a prevalent mutation while keeping healthy cells intact. @doudna-lab.bsky.social @innovativegenomics.bsky.social @ucsanfrancisco.bsky.social @ucberkeleyofficial.bsky.social

Scientists at Gladstone Institutes have developed a thinking microscope powered by AI. They can ask it to figure out what it takes to make sick cells with Parkinson’s disease behave like healthy ones. Beyond that goal, the scientists are not giving the microscope any instructions.

The Bay Area has been recognized as one of the nation’s leading biopharma hubs—and Gladstone is helping shape its future. Earlier this year, we announced plans to expand in Mission Bay with new lab space that will support scientists working at the intersection of biology, medicine, and AI.

A team of scientists at Gladstone, led by Steven Finkbeiner, invented a thinking microscope that can conduct its own experiments. They intend to use it to find new ways of treating neurodegenerative diseases, such as Alzheimer’s and Parkinson’s.

NIAID (@niaidnews.bsky.social) has awarded $6M to launch a coordinated US phage therapy research network — 3 new centers! Excited our Stanford Center for Phage Pharmaceuticals (@stanfordmedicine.bsky.social) is one, & to work w/ @gladstoneinst.bsky.social & @pghphageprogram.bsky.social! 🧵 1/

For Cancer Immunotherapy Month: When Will Immunotherapy Work on Common Cancers? Gladstone Investigator Karin Pelka is helping answer that question by studying how tumors interact with the immune system in order to make immunotherapy more effective for cancers like breast, lung, and prostate cancer.

Where does the brain send its waste? Research led by Gladstone Investigator Andrew Yang mapped the pathways that help clear proteins from the brain. Read more to learn what this could tell us about Alzheimer's disease 👉 https://bit.ly/4e8ApQp

Twenty years after the discovery of iPS cells changed biomedical research, scientists are reflecting on its lasting impact—and future potential.

Thanks to the new methods they developed, Gladstone researchers can now address long-standing questions about how the brain clears waste, including how waste removal changes with disease and aging. Read more 👉 https://gladstone.org/news/mapping-how-brain-takes-out-its-trash

A new study from Gladstone offers the clearest picture yet of how the brain normally takes out its trash—and what happens when those routes fail.

The recent edition of "This Week in Virology" delves into an exciting study by Magnus Hoffmann and colleagues, who share data supporting the development of a next-generation booster vaccine that may protect against emerging SARS-CoV-2 variants. Listen here 👉 https://bit.ly/4ob85Sb

The Ogawa-Yamanaka Stem Cell Prize, established in 2015, recognizes individuals whose original translational research has advanced cellular reprogramming technology for regenerative medicine. Learn more about the current and past winners.

We're launching a major collaborative Center aimed at accelerating phage therapy @gladstoneinst.bsky.social. High-throughput experiments with engineered phages (my lab) and strains (Silas Lab), organoids (Ott Lab), and AI (Pollard Lab). gladstone.org/news/gladsto...

A team of Gladstone scientists—including Katie Pollard, Melanie Ott, Seth Shipman, and Sukrit Silas—will lead one of three new national centers dedicated to accelerating the development of phage therapy. @theottlab.bsky.social @seth-shipman.bsky.social

🚨 NEW 🚨 "Linkage of nucleotide and functional diversity varies across gut bacteria" from the Pollard Lab in @pnas.org https://bit.ly/4dSNxsY

How do the waste proteins made inside the brain find their way out? Researchers Yuichi Chayama, Nalini Rao, Andrew Yang, et al. @gladstoneinst.bsky.social have devised a way to track the exact routes debris uses when exiting brain. Learn More @cellpress.bsky.social www.cell.com/cell/fulltex...

Congrats to Andrew Yang who received the 2026 Sobrato Prize. The prize honors scientists whose breakthroughs in brain research have high potential for patient impact.

How does the brain drain its waste? A new method developed at @gladstoneinst.bsky.social maps the routes proteins takes out of the brain. The result: unexpected biology, and new insight into how disease disrupts the brain's cleanup system. gladstone.org/news/mapping...

Scientists at @gladstoneinst.bsky.social have developed a new tool to trace how the brain clears ‘waste’, uncovering surprising new biology about how it keeps itself healthy >>> www.biotechniques.com/neuroscience... 🧪

Hope can come from unexpected places. Researchers at Gladstone are exploring how existing drugs may be repurposed to tackle brain diseases like Alzheimer’s, opening new possibilities for faster treatments and better outcomes. https://womensbrainhealth.org/think-tank/repurposed-for-hope

🚨 NEW PUBLICATION 🚨 "Physiological brain clearance architecture revealed by neuronal protein tracing" from the Yang Lab in @cp-cell.bsky.social

Deepak Srivastava offers commentary on a novel approach to heart failure that involves a stem cell-based patch to regenerate cardiac muscle, in @statnews.com

For Julia Kaye, the path to studying neurological disease is deeply personal. Inspired by her mother’s experience with multiple sclerosis, Kaye has dedicated her career to better understanding diseases of the brain—and how science can help uncover new treatments.

Seth Shipman (@seth-shipman.bsky.social ) was recently interviewed for an upcoming documentary exploring where visual art and science intersect. His lab builds molecular tools to study and treat disease—and he was the first to store and reconstruct moving images inside the DNA of living cells.

Gladstone scientists developed a new tool to trace how the brain clears “waste,” uncovering surprising new biology about how it keeps itself healthy. Published in @cellpress.bsky.social

Nobel Prize-winning scientist Shinya Yamanaka shares the deeply personal and touching story behind the prestigious Ogawa-Yamanaka Stem Cell Prize. Nominations are open for the 2026 prize. Learn more: https://bit.ly/3amoRqH

Deepak Srivastava, MD, describes the scientific foundations of a phase 1–2 study of stem-cell–derived ventricular assist tissue transplanted onto the epicardial surface of failing human hearts. Learn more: https://nej.md/4o0ViBS @gladstoneinst.bsky.social

In our latest issue of Cell Signals, discover how a new AI-powered tool is reshaping scientists’ understanding of DNA accessibility inside cells, unpack the growing concerns around a rare hantavirus outbreak, and learn how to submit a nomination for the 2026 Ogawa-Yamanaka Stem Cell Prize.

A new study upends long-held view about how DNA is stored, explaining how subtle shifts in gene activity contribute to cancer, aging, and other complex diseases.

🚨 NEW! 🚨 Learn more about this AI model with an expanded pretraining dataset of more than 100 million single-cell human transcriptomes. @natcomputsci.nature.com

We're currently accepting nominations for the 2026 Ogawa-Yamanaka Stem Cell Prize. In this clip, Deepak Srivastava shares how the Ogawa-Yamanaka Prize has become one of the world's most significant stem cell awards. Learn more about the prize: https://bit.ly/3amoRqH

Women’s health research has long been overlooked and underfunded but Gladstone’s Barbara Engelhardt is moving the field forward. She leads menstrual-cycle research, collecting biometric data while considering privacy and data security.

A new genetic roadmap reveals hundreds of hidden players in #HIV infection, including two proteins that stop HIV in its tracks.

For a long time, scientists have been looking for ways to precisely edit the genomes of bacteria. It would allow researchers to engineer bacteria for manufacturing, studying how gut microbes interact, or fighting drug-resistant infections.

🚨 NEW 🚨 "Cell-type-specific APOE4 cascade across the Alzheimer’s disease continuum"

In this video, Yadong Huang and Yaqiao Li explain how repurposed drugs that are already approved by the FDA can expedite potential new treatments for Alzheimer’s disease. Watch their part starting at 51:35.

Scientists from Gladstone along with with researchers at @ucberkeleyofficial.bsky.social and @ucsanfrancisco.bsky.social developed a heart-on-a-chip platform that could potentially accelerate new treatments for heart failure and cardiovascular disease.

Every cell in the human body squeezes over six feet of #DNA into a miniscule speck invisible to the naked eye—like compressing a whole house into a single sugar cube.

Steve Finkbeiner, SLAS 2026 Innovation Award winner, talks about his lab’s development of an Al-powered “thinking microscope" and how it's dramatically accelerating research into neurodegenerative diseases and beyond.

The Ogawa-Yamanaka Stem Cell Prize recognizes individuals whose translational research has advanced cellular reprogramming technology for regenerative medicine. It also celebrates the landmark discovery of iPS cells by Shinya Yamanaka. But what are iPS cells? Learn more 👇

Years before he conducted the research that would earn him a Nobel Prize, Shinya Yamanaka was a postdoctoral scientist at Gladstone Institutes, studying genes. There, he helped discover a gene that’s essential for early embryonic development. Then, the story pauses, until now.

This week, we're proud to celebrate our Research Associates. RAs bring expertise, rigor, and joy to our science every single day. RA Appreciation Week is a tradition that started right here at Gladstone in 2020, championed by our Research Associates Committee. #ScienceCommunity

Despite being a baby's primary food source, so much about milk production is still unknown. Sarah Nyquist is changing that. Sarah is a bioinformatics fellow researching how breast milk is made. Learn how her own experience as a mother has impacted her research. #MothersDay

Ryan Corces received a major neuroscience award for his work on Alzheimer’s genetics using artificial intelligence tools. The prize supports innovative research into causes behind familial cases lacking known gene mutations.