🚨 NEW PUBLICATION🚨 "Programmable kinetic barcoding for multiplexed RNA detection with Cas13a" @natbiomedeng.nature.com @doudna-lab.bsky.social @theottlab.bsky.social https://www.nature.com/articles/s41551-026-01642-6

Cell-extrinsic and -intrinsic mechanisms driving lymphocyte-mediated control of HIV rebound after ART interruption @cp-immunity.bsky.social @gladstoneinst.bsky.social #Roan @theottlab.bsky.social #Greene www.cell.com/immunity/ful...

In our new work published in @natbiomedeng.nature.com in collaboration with @theottlab.bsky.social and @doudna-lab.bsky.social, we introduce "interfering" guide RNAs (igRNA) for CRISPR-Cas13a that regulate enzyme activity after activation. Congrats to all the authors! www.nature.com/articles/s41...

We honor the life of J. Michael Bishop, whose groundbreaking discoveries helped transform our understanding of cancer and opened new paths for treatment. His legacy will continue to inspire generations of scientists and clinicians. Rest in peace.

Antiretroviral therapy transformed #HIV care—now we need a cure. Insights from Melanie Ott on what comes next.

Congrats, Nadia!

🚨 🚨 NEW PUBLICATION 🚨 🚨 "The Mac1 ADP-ribosylhydrolase is a therapeutic target for SARS-CoV-2" from @theottlab.bsky.social in @elife.bsky.social

Tune in for our event on TikTok LIVE: “HIV Cure Lab Tour + Q&A"! 📆 Monday, December 1, 2025 at 10am PT 📍 Live on TikTok via @RaifDerrazi 🔗 Register: tiktok.com/live/event/7...

The Gladstone Institute of Virology has taken on a new name: the Gladstone Infectious Disease Institute. Check it out here: gladstone.org/news/beyond-...

Check out Dr. Melanie Ott's recent opinion piece on the SF Standard: sfstandard.com/opinion/2025...

💉🧬 We're kicking off National Immunization Awareness Month with our faculty spotlight, Dr. Melanie Ott! Head to our Instagram to hear her take on how immunizations keep us safe—and how you can help to keep vaccines accessible for all: www.instagram.com/reel/DM_A9Sc... @theottlab.bsky.social

Congratulations Fran! @franzapatero.bsky.social

Congratulations to @juliaprigann.bsky.social for being awarded the 2025 CFAR Excellence in Basic/Translational Science Award! cfar.ucsf.edu/user/11703

We are delighted that we could help with this work. Check it out here: authors.elsevier.com/c/1lEffL7PXu...

Scientists from Gladstone and UCSF have developed drug candidates that could prevent future coronavirus pandemics. @theottlab.bsky.social @ucsfmedicine.bsky.social @qbi-ucsf.bsky.social

Scientists develop powerful drug candidates that could head off future coronavirus pandemics. @theottlab.bsky.social @ucsfmedicine.bsky.social @qbi-ucsf.bsky.social

🚨 NEW PUBLICATION 🚨 "Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MPro inhibitors with potent in vivo efficacy" @theottlab.bsky.social @ucsfmedicine.bsky.social @qbi-ucsf.bsky.social

🎧 Listen to this podcast featuring virologist Melanie Ott. Ott discusses how measles works and the way it breaks into our body to make us sick. @theottlab.bsky.social

Thank you to everyone who attended the HIV Mini-Symposium on March 13th! Our next Mini-Symposium will be September 23, 2025 titled 'Viral Landscapes: How to Comprehensively Monitor Evolutionary Trajectories'. We hope to see you there! www.youtube.com/watch?v=vjpe...

Did you know that viruses don’t just infect humans—they also target bacteria in our microbiome? These viruses, called phages, play a crucial role in shaping our health and could be the key to fighting antibiotic-resistant bacteria. In this short, @theottlab.bsky.social explains.

Virologist Melanie Ott (@theottlab.bsky.social) speaks to KUSI News about the measles outbreak and other infectious diseases.

At Gladstone, researchers are working toward curing HIV for good. Their work also sheds light on how viruses influence our long-term health. Melanie Ott, MD, PhD, director of the Gladstone Institute of Virology explains why curing HIV remains a crucial scientific challenge. @theottlab.bsky.social

What does the bird flu outbreak mean for public health? Virologist Melanie Ott (@theottlab.bsky.social) discusses how H5N1 in cows could affect virus evolution and why increased surveillance is important.

Melanie Ott talks about the ongoing measles outbreak, explains how vaccination can lower the risk of Alzheimer’s, and shares other positive “side effects” of vaccines. @theottlab.bsky.social

In an interview with @amfarofficial.bsky.social, Melanie Ott (@theottlab.bsky.social), discusses the future of HIV research, and describes how lessons from the field have laid a strong foundation for fighting other viral diseases.

Gladstone recently hosted the German Center for Research and Innovation San Francisco for their Innovation Summit. The event addressed the challenge of sharing data across sectors, institutions, and borders, a key question for global health. Speakers included Melanie Ott (@theottlab.bsky.social)

HIV research has led to breakthroughs in antiviral treatments & cancer therapies. amfAR’s Dr. Andrea Gramatica & Dr. Melanie Ott (@theottlab.bsky.social) discuss how investing in one virus drives medical innovation. www.amfar.org/news/shaping...

Please join us at our mini-symposium on the latest advancements in HIV persistence next week. gladstone.org/events/hiv-p... via @gladstoneinst.bsky.social

Yesterday we hosted the German Consulate and the German Research Foundation for their Global Innovation Summit at @gladstoneinst.bsky.social Thank you to everyone involved! Photos by © Barak Shrama

Melanie Ott talks to Newsweek about the risk of bird flu from drinking milk. Check it out! www.newsweek.com/can-you-get-...

Our CEO, Eric Verdin answered questions about the administration’s proposed budget cuts to the NIH at a hearing before the Senate Special Committee on Aging this afternoon. Hear his exchange with Angela Alsobrook D-MD here: youtu.be/XrhHldez1AI

Gladstone virologist Melanie Ott talks to Salon about the #BirdFlu. Read more to learn how you can best understand and manage your risk.

Interesting bioRxiv preprint by a team around Charles Craik, Adam Renslo and @theottlab.bsky.social. Inhibitors for Mpro of coronaviruses based on a dihydrouracil chemotype and a propargyl amide warhead as reactive group to engage the catalytic cysteine. #chemsky #ChemBio www.biorxiv.org/cont...#chemsky

Thrilled to share our latest work identifying that #SARSCoV2 #Omicron variants harboring an L260F mutation in NSP6 have enhanced replication and pathogenesis. A not so brief thread 🧵