Online now: Influenza hijacks myeloid cells to inflict type-I interferon-fueled damage in the heart

Repression of RIPK1 kinase by INPP5D inhibits expression of diverse proinflammatory mediators and late-onset Alzheimer’s disease risk factors @cp-immunity.bsky.social www.cell.com/immunity/ful...

Repression of RIPK1 kinase by INPP5D inhibits expression of diverse proinflammatory mediators and late-onset Alzheimer’s disease risk factors @cp-immunity.bsky.social www.cell.com/immunity/ful...

Online now: Repression of RIPK1 kinase by INPP5D inhibits expression of diverse proinflammatory mediators and late-onset Alzheimer’s disease risk factors

#WeekendRead! #FirstLove #IL2power #IL10power #InterferonPower! Delaloy, Gauthier &co show @cp-immunity.bsky.social that IL2 favors a regulatory program in B cells that, together IFNg, induces IL10 production, protecting against neuroinflammation! Exciting paper 🤗! www.cell.com/immunity/ful...

Online now: Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition

Online now: B cell-intrinsic IL-2 signaling regulates inflammation by promoting IL-10 expression in CD25+ age-associated B cells

Online now: Meningeal B cells: Emerging players at the brain border

Online now: Stepwise epigenetic signal integration drives adaptive programming of cytotoxic lymphocytes

Commensal-myeloid crosstalk in neonatal skin regulates IL-1 signaling and cutaneous type 17 inflammation @cp-immunity.bsky.social www.cell.com/immunity/ful... @scharschmidtlab.bsky.social

Meningeal B cells: Emerging players at the brain border. @cp-immunity.bsky.social www.cell.com/immunity/ful...

Excited to share my paper published today in @cp-immunity.bsky.social! We find that when CTLs integrate antigen and cytokine signaling, the timing of these cues matters - shedding light on an old question: Why do NK cells sometimes behave like CD8+ T cells? www.sciencedirect.com/science/arti...

Online now: Pre-existing neutralizing antibodies against cattle-transmitted influenza A virus H5N1 are detectable in unexposed individuals

Online now: Commensal-myeloid crosstalk in neonatal skin regulates interleukin-1 signaling and cutaneous type 17 inflammation

Online now: Scalable TCR synthesis and screening enable antigen reactivity mapping in vitiligo

Online now: A type I interferon-mitochondrial axis regulates efferocytosis and interferon-stimulated gene induction in macrophages

Exosite-mediated targeting of GSDMB by dimeric granzyme A in lymphocyte pyroptotic killing @cp-immunity.bsky.social www.cell.com/immunity/ful...

Tumor-associated macrophages directly stimulate neurite outgrowth, revealing a dual role in enhancing intratumoral nerve growth and promoting neural repair after severe spinal cord injury @cp-immunity.bsky.social www.cell.com/immunity/ful...

Online now: Tumor-associated macrophages enhance peripheral nerve tumor infiltration and spinal cord repair

Online now: Exosite-mediated targeting of GSDMB by dimeric granzyme A in lymphocyte pyroptotic killing

Last chance to submit an abstract and be considered for a short talk @CellSymposia #CSImmuneHomeostasis26 taking place on May 11–13, 2026 in Shanghai, China Submit here: http://dlvr.it/TQWYrp

CS: Host-microbiome dynamics abstract deadline extended to Feb 6. Share your research with leading scientists exploring the ecology of the human microbiome, its influence on host physiology & its complex interactions with the immune system. http://dlvr.it/TQVnf5

Human nasal passages defend against the common cold and help determine how sick we get. Read the full article from @ellenfoxman.bsky.social & colleagues: www.cell.com/cell-press-b... #ResearchWithInfinitePotential

Online now: Innate lymphoid cells activated by the cytokine TL1A link colitis to emergency granulopoiesis and the recruitment of tumor-promoting neutrophils

Commensal-derived trehalose monocorynomycolate triggers γδ T cell-driven protective ocular barrier immunity #gdTcells @cp-immunity.bsky.social

A commensal Corynebacterium-derived lipid that activates IL-17⁺ γδ T cells via T cell receptor and IL-1 signaling, enhancing barrier defenses @cp-immunity.bsky.social www.cell.com/immunity/ful...

Commensal-derived trehalose monocorynomycolate triggers γδ T cell-driven protective ocular barrier immunity: Immunity www.cell.com/immunity/ful... @cp-immunity.bsky.social

Online now: Commensal-derived trehalose monocorynomycolate triggers γδ T cell-driven protective ocular barrier immunity

Folic acid suppressed this axis in mice. In a clinical trial, it reduced cholangitis by 71% and liver transplantation by 73% in biliary atresia infants. I find this a very intriguing mechanism Immunity doi.org/10.1016/j.im... 🧪 3/3

Scientific editor Bruce Koppelman speaks with Dr. Bing Su (Shanghai Jiao Tong University) about the vision behind @CellSymposia #CSImmuneHomeostasis26 taking place May 11–13, 2026, Shanghai, China. Watch the interview: http://dlvr.it/TQLQRk

How can a common virus contribute to a rare disease? A new @cp-immunity.bsky.social study from @biomedizin.unibas.ch links EBV to early MS-like lesion formation by showing how B cells can act at the very start of the disease process. 🔗 doi.org/10.1016/j.ce... @unibas.ch #EBV #MultipleSclerosis

@cp-immunity.bsky.social preview on IL-10-producing Treg cells that restrain tumor growth by suppressing IL-17 production in colorectal cancer www.cell.com/immunity/ful...