⏰ Only until 15 Oct 2025 to submit your abstract & grab early-bird registration! Join us in Paris for the French DCs Meeting — featuring an outstanding speaker lineup. Program 👇 www.cfcd.fr/meeting/prog... Registration 👇 docs.google.com/forms/d/e/1F... #DCMeeting2025 #Immunology

E. Tomasello & team at @ciml.bsky.social challenge the prevailing dogma of plasmacytoid DC's role in anti-viral immunity, by showing that they are deleterious in respiratory viral infections. CONGRATS 🍾 can't wait to hear more about it the next French DC society meeting👇 www.cfcd.fr/meeting/prog...

🚨A new study in @elife.bsky.social "reveals crucial roles of cDC1 in atherosclerosis progression and provides insights into the development of therapies by targeting cDC1 through Xcl1"🚨 👇👇 elifesciences.org/articles/107...

The 8th Symposium of the French Network on Monocytes-Macrophages (SoMM2025), will take place in Lyon, France, on November 7th, 2025 📝 Registration (free but mandatory) and abstract submission are now open until October 10th, 2025 : somm2025.sciencesconf.org Amazing line up 👇👇👇

A targetable epigenetic node of myeloid progenitor dysregulation that sustains immunosuppressive lung tumor microenvironment, a target for improving immunotherapy outcomes @nature.com @miriammerad.bsky.social @sinaiimmuno.bsky.social www.nature.com/articles/s41...

Myeloid cells drive #neuroinflammation in #MultipleSclerosis by promoting immune activation in the #CentralNervousSystem. This study identifies SLAMF5 as a key myeloid receptor that regulates this process, showing that its blockade reduces disease progression @plosbiology.org 🧪 plos.io/3Vb7xhx

Congratulations to Carola García de Vinuesa on receiving the 2026 FEBS | EMBO #WomenInScience Award! She is recognized for advancing the understanding of autoimmune diseases and for her impact within the #LifeSciences community, in particular in public engagement: www.embo.org/press-releas... 🧪

Exciting work in @scienceimmuno.bsky.social : boosting Dendritic Cells with FLT3L + CD40 agonists reactivates T cell immunity in pancreatic cancer—shown in both mice and patients. 👇 www.science.org/doi/10.1126/...

Fantastic new story @jkagan1.bsky.social & friends showing that human dendritic cells can become hyperactive activating the inflammasome without dying, & that this approach can be used in mice and NHPs to potentiate anti-influenza vaccine responses! 👇👇👇

🚨 New in @natimmunol.nature.com : @idoyagalab.bsky.social shows that plasmacytoid DCs can reprogram into cDC2s after TNF-α stimulation. Fascinating plasticity! 👇 www.nature.com/articles/s41...

🤯 By spitting out DNASE1L3, Dendritic Cells chew up NETs and make immunotherapy hit harder against tumors. Cool science in @cp-cancercell.bsky.social 🧬✨ www.cell.com/cancer-cell/... #Dendritic #Immunology #CancerResearch

The laboratory of Filipe Pereira @lunduniversity.bsky.social in @cp-immunity.bsky.social "uncover transcriptional circuits that control DC diversification" Very cool approach and can't wait to hear more about it the next French DC society meeting👇 www.cfcd.fr/meeting/prog...

🚨 2025 French Dendritic Cell Society (CFCD) Symposium 🚨 Program: www.cfcd.fr/meeting/prog... When: December 4th - 5th, 2025 Where: Institut Curie in Paris Register: 👇 docs.google.com/forms/d/e/1F... Deadlines - October 15th, 2025: Early Birds + Abstracts - November 15th, 2025: Late abstracts

The group of @florentginhoux.bsky.social "delineate the development of type 2 conventional DCs and plasmacytoid DCs in mice, defining distinct ontogenies and transcription factor dependencies". Bravo the team 🍾 👇https://www.nature.com/articles/s41590-025-02208-5

New insights in @nature.com on how microbiota can drive anti-tumor immunity. It appears that CD103+ CD11b- gut cDCs play a central role in the process. Congrats to the Benno. Y and Nishikawa. H labs 👇 www.nature.com/articles/s41...

A short spotlight in @cp-immunity.bsky.social by Brian Kelsall. on the recently described RORγt+ DCs and their function in inducing intestinal tolerance. www.sciencedirect.com/science/arti...

Congrats to the Henao-Mejia lab for this impressive work in @cp-immunity.bsky.social showing that targeting mitochondrial complex IV in TAMs boosts interferon signalling and ultimately anti-tumor immunity. 👇 www.cell.com/immunity/abs...

🚨very nice story in @nature.com showing that "disruption of dendritic cells motility in tumors promotes immune evasion, and its enhancement offers a promising direction for DC-centric immunotherapy"🚨. www.nature.com/articles/s41...

Congrats to the @masslab.bsky.social for this beautiful story in @nature.com showing how the programming of liver resident macrophages, known as Kupffer Cells, by maternal obesity triggers fatty liver disease. www.nature.com/articles/s41...

✈️ Travel Grants for Junior Scientists! The French DC Society (CFCD) is awarding 2 travel grants to support junior researchers attending scientific conferences. 🔗 Application Details: www.cfcd.fr/news/88-trav... 🗓️ Deadline 15th of September 2025.

🔥🔥2025 Langerhans cells International Workshop🔥🔥 Sept. 3-5 2025 in beautiful Saint Louis, Missouri All you need to know 👇👇👇

#LocationLocationLocation! #NewVirusSensingModality! Lahaye, @manellab.bsky.social &co show @cp-cell.bsky.social that nuclear cGAS senses viruses by recognizing centromeric DNA amplification caused by viral effectors that degrade centromere proteins! www.cell.com/cell/abstrac...

Delighted to share our paper describing how type I interferon promotes caspase-11 hyperactivity in models of PolG-related mitochondrial disease. Thanks to all co-authors and the POLG Foundation for for their support. www.nature.com/articles/s41...

Registration Open for the 2025 French Dendritic Cell Society (CFCD) !! www.cfcd.fr/meeting/prog... When: December 4th - 5th, 2025 Where: Institut Curie in Paris How: 👇👇👇 docs.google.com/forms/d/e/1F... Deadlines - October 15th, 2025: Early Birds + Abstracts - November 15th, 2025: Late abstracts

Congratulations to Sunkyung Kim and Ken Murphy, who, together with their team, reveal key mechanisms of transcriptional control in cDC1 development www.science.org/doi/10.1126/...

@reisesousalab.bsky.social and team identify a new function for DNGR1 in the regulation of conventional DCs progenitors proliferation and migration in @jem.org. Congrats 👇 rupress.org/jem/article/...

This time in @science.org a study by the group of @chrysothemisbrown.bsky.social show that Thetis Cells, which are a population of RORγt+ antigen presenting cells, contribute to tolerance to food proteins. 👏Congrats for this nice work👏 www.science.org/doi/10.1126/...

Reprograming DC with PROTAC STAT3 degraders to enhance anti-tumor immunity ! Super work on @nature.com from Weiping Zou, Shaomeng Wang and coll. 👏👏 www.nature.com/articles/s41...

The team of Melanie Greter shows in @cp-immunity.bsky.social that "interleukin-34-dependent perivascular macrophages promote vascular function in the brain". 👊 Congrats for this beautiful work 👊 www.cell.com/immunity/ful...

The @movahedilab.bsky.social lab shows in the @cp-immunity.bsky.social paper that monocytes are capable of efficiently replacing microglia and border-associated macrophages. Congrats for this beautiful work www.cell.com/immunity/ful...

A study in @ science immunology shows that Siglec-E regulates dendritic cell's activation and and their ability to trigger T cell–mediated transplant rejection. www.science.org/doi/abs/10.1...

A study in Science immunology shows the type of dead cell ingested by macrophages governs their functional plasticity. YOU ARE WHAT YOU EAT www.science.org/doi/10.1126/...

Thrilled to share that our paper is now published in Immunity @cp-immunity.bsky.social ! 🎉 It’s been a long journey, and I’m incredibly grateful to all my co-authors—especially Dr. Teruyuki_Sano—for your dedication. This wouldn’t have been possible without you! www.cell.com/immunity/ful...

Fresh out of @nature.com the group of Dan Littman, identify a subset of intestinal tolerizing DC (tolDC) expressing Prdm16+ and RORγt+ that are essential regulators of T cell responses to food and microbial antigens. www.nature.com/articles/s41...

The group of Jean-Pierre Gorvel @ciml.bsky.social identify in @jclinical-invest.bsky.social novel roles of SLAMF7 and SLAMF8 in finely tuning human plasmacytoid DC responses to intracellular bacterial infections. www.jci.org/articles/vie...

A new study in @jem.org shows that enhanced TLR7-mediated type I interferon production by plasmacytoid DCs likely contributed to COVID-19 caused chilblains. rupress.org/jem/article/...

Bravo 👏 to the team of W. Kastenmüller & G. Gasteiger for showing in @science.org that T cell priming by DCs occurs in two phases, including a 1st educational phase and a second phase that is key for the proliferation and differentiation of T cell clones. www.science.org/doi/10.1126/...

It used to be thought that T-cell priming occurred as single phase. Now we know it takes two. www.science.org/doi/10.1126/... @science.org

Kudos to @sancholab.bsky.social and @swculek.bsky.social for this work in @naturecomms.bsky.social showing that "that cDC1-based vaccination excels at immune memory induction and prevention of cancer recurrence" www.nature.com/articles/s41...

Fascinating work by Raffaella Molteni, Samuele Ferrari and coll. that provides mechanistic dissection of VEXAS syndrome @naturemedicine.bsky.social 👏👏👏 www.nature.com/articles/s41...

👉 When splenic metallophilic marginal zone macrophages do antigen cross-presentation equally well as conventional DC1. Congrats to the team of Peter van Endert from @inem-necker.bsky.social for this work published in @cp-immunity.bsky.social www.cell.com/immunity/abs...

A tour de force by the team of Marco Colonna describing in @cp-cell.bsky.social the role of "lymphoid RORγt+ Dendritic Cells in maintaining intestinal immune balance and preventing conditions like food allergies". www.cell.com/cell/fulltex...

🚨 JOB OFFER in our lab at Institut Pasteur 🚨 We are looking for a postdoc! Please repost 🙏

⚠️ SAVE THE DATE ⚠️ CFCD meeting - December 4th-5th 2025 Unveiling the future of Dendritic Cell and Macrophage biology in health and disease 🔥🔥🔥 Venue : Institut Curie in Paris Amazing keynotes by Yasmine Belkaid (Institut Pasteur) Dan Litmann (NYU) Registrations open soon

Cool paper by the group of @msmelanoma.bsky.social in @naturecancer.bsky.social showing that tumor secreted growth factor midkine rewires DCs toward a tolerogenic state and promotes tumor immune escape. www.nature.com/articles/s43...

The group of a former CFCD board member Jenny Valladeau-Guilemond, shows in @naturecomms.bsky.social that type III interferons boost plsamcytoid DC responsiveness to TLR7 stimulation and prevent their functional blockade by tumor-derived factors (TGF-b and PGE2). 👊 www.nature.com/articles/s41...

The group of @idoyagalab.bsky.social publishes a new study in @jem.org that shows that "CD301b+ monocyte-derived dendritic cells mediate cancer resistance to radiotherapy" rupress.org/jem/article/...

It is with profound sadness that we mourn the loss of our colleague and friend, Dr. Marlene Dreux.

🚨 available postdoc position 🚨 in the laboratory of @guermonprezlab.bsky.social at the Pasteur institute in Paris, France, to work on DC function within tumors. Exciting project, amazing institute and so on...

🚨Registrations are open🚨 Join us in Lausanne Switzerland October 1-2 for an exciting symposium on innate immunity with oustanding invited speakers, short talks selected from submitted abstracts and poster sessions. Attendance is limited to 150 participants!