Preprint: Targeting Neoantigens Conserved Across Organs and Species Overcomes Tumor Immune Escape @bhardwajlab.bsky.social @sinaiimmuno.bsky.social papers.ssrn.com/sol3/papers....

I am thrilled to announce that our latest paper is out now in @cp-cancercell.bsky.social! 1/n www.sciencedirect.com/science/arti...

New **RESOURCE** in @natcancer.nature.com - a landmark single-cell Immune Atlas of multiple myeloma—1.3M+ bone marrow cells from 337 patients. Led by the Immune Atlas Consortium with major contributions from Sacha Gnjatic, @edgargk.bsky.social & HIMC profiling teams 🧐 www.nature.com/articles/s43...

Our paper is out in @pnas.org Big congrats to @jdllkss.bsky.social , and huge thanks to @belkaidlab.bsky.social for the tremendous support. We explore how sensory neuron hyperinnervation regulates itch. @sinaiimmuno.bsky.social @sinaibrain.bsky.social @Dermatology at Mount Sinai.

🎁 Happy holidays from our laboratory to yours. 🎁 Here’s to standing up for science and to a more peaceful and kinder year ahead!

🚨 REVIEW 🚨 Amir Horowitz & Peter Heeger in @natrevneph.nature.com highlight how diverse NK cells in the kidney support immune surveillance but also drive injury in many diseases and contribute to transplant damage, with high-resolution profiling revealing new therapeutic targets. 🧐 rdcu.be/eUgor

Paper out now in @natbiotech.nature.com by @yizhoudonglab.bsky.social describing new LNP mRNAs for combatting bacterial infections… helping the immune system clear the pathogens while limiting tissue damage…

For an expert opinion on the recent report that mRNA COVID vaccines may help immune checkpoint blockade work in patients with advanced lung cancer and metastatic melanoma, read this News & Views in @natrevclinonc.nature.com by Sacha Gnjatic FREE >>> rdcu.be/eQYcu

In Dermatology Times, @itchdoctor.bsky.social highlights that inflammation is a common thread across diseases throughout the body. Studying how it goes awry in one organ—like the skin—can reveal why it misfires elsewhere. www.dermatologytimes.com/view/brian-k...

📣 NEW STUDY 📣 @cp-immunity.bsky.social by Maria Lafaille's lab shows how long-lived IgE-producing plasma cells survive & sustain allergy without continued allergen exposure: maturing in spleen & bone marrow with a unique survival program that resists cell-death signals 🧐 www.cell.com/immunity/abs...

Excited to share our LongTrack study out in @natmicrobiol.nature.com today! Fecal microbiota transplant (FMT), donor 💩 => patients' gut, is an effective treatment for recurrent C. difficile infection & is being evaluated for Inflammatory Bowel Diseases (IBD) & other conditions 1/ 📄 rdcu.be/eL8mR

Also tomorrow, Cindy Xintong Li from the University of Oxford will present a preprint about how TCR activation impairs CAR-T cytotoxicity against separate target cells. @kischober.bsky.social www.biorxiv.org/content/10.1...

Tomorrow, Annie Khamhoung from Mt.Sinai will present a pre-print on the role of brain infiltrating T-cells in microglial dysregulation and neuronal loss following subarachnoid haemorrhage. @ElisaEzanier @MarioNegriIRCCS www.biorxiv.org/content/10.1...

Our new review in @natbiomedeng.nature.com is out! RNA-loaded lipid nanoparticles (LNPs) have huge potential—but their strong liver and immune cell uptake has mostly confined them to vaccines and liver therapies. We explore how to move beyond those limits. free to read 🔗 rdcu.be/eLxGs

Immunotherapy researcher Miriam Merad from Icahn Mount Sinai says the reason that cancer research has slowed is because of funding issues, which is something taxpayers don’t have to accept. “We fight for patients, we fight for science, and we have to fight for progress.” #STATSummit

Add your name ✍ at www.nycures.org so Albany sees 10,000 scientists calling for the future of biomedical research to be built right here in New York. Our first email to members goes out soon—introducing the statewide biomedical institute we’re proposing and how you can help power it forward.

Looking forward to this live episode of @microbetv.bsky.social with my dear friend and rockstar immunologist @diehllab-mskcc.bsky.social #holidayfun #immune100

Wondering what *exactly* we’re up to? Our first coalition email is about to go out—introducing the statewide biomedical institute we’re proposing and how you can help power it forward THIS WEEK! Sign up now so you don’t miss it: www.nycures.org/

Sleep is very good for the immune system!

🧪Excited to co-present this @standupforscience.bsky.social event next week with UW's Dr. Ryan Kelly We'll cover how to effectively engage in public comments, to help shape public policy at all levels, federal to local. Attend in person or virtually! RSVP: act.standupforscience.net/events/power...

The immune system is a formidable defense that can destroy our own cells to keep us safe from viruses and cancer. That power demands effective checks & balances to prevent autoimmunity. Like the regulatory T cells discovered by this year's Nobel Prize winners! www.newscientist.com/article/2498...

The BIGGEST impact you can have with 1 minute today ⏱️ Add your name to show NY is ready for a statewide biomedical institute. CA’s CIRM & TX’s CPRIT proved it works—billions returned, jobs created, cures accelerated. Let’s do even better for New York. ✍️ www.nycures.org/

“States like New York have an opportunity to position ourselves as real leaders in so many different areas.” @governor.ny.gov Like her, we believe NY is ready for revitalization—by launching a state-wide biomedical institute that boosts jobs, the economy & cures. www.youtube.com/watch?v=WVtF...

Check out our latest in @cp-trendscancer.bsky.social where rockstar PhD student @laurarosenberg.bsky.social reviews cancer therapies known to induce innate immune responses through the reactivation of Transposable Elements.

The new #NSF #GRFP application now excludes 1000’s of students, including those who were told they could apply this year, or who planned to apply next year. We have a new specific petition urging #NSFGRFP undo this harmful action. If you are impacted sign here: laurenkuehne.github.io/grfpChanges/

We're excited to share our latest work: "Targeting neoantigens conserved across organs and species overcomes tumor immune escape"! Thanks to the team at @sinaiimmuno.bsky.social ! www.biorxiv.org/content/10.1...

Also tomorrow from #PreprintHub1 Shelley Herbrich from MD Anderson will present a #preprint from @LHooperLab on how the gut microbiota regulates intestinal T cell development. www.biorxiv.org/content/10.1...

Tomorrow #PreprintHub1 is starting for the 2025-2026 season! Laura Rosenberg from Mount Sinai will present a #preprint by the @BelkaidLab on how endogenous retroelements promote tolerance to dietary antigens. www.biorxiv.org/content/10.1...

🔬Our paper from the @miriammerad.bsky.social lab is now online! This is a story shaped over years of cross-disciplinary endeavor at @sinaiimmuno.bsky.social and labs across the world. 🧵: www.nature.com/articles/s41...

📝NEW STUDY📝 Cancer's first punch when battling the immune system may be rewiring myeloid progenitors in bone marrow so they become suppressive tumor macrophages blunting T-cell attacks. Find out how in @nature.com from @samhegde.bsky.social & @miriammerad.bsky.social 🧐 www.nature.com/articles/s41...

📢 📢📢📢 📢 Mechanosensitive fibroblasts fuel strictures via YAP/TAZ signaling—opening doors to new anti-fibrotic therapies. Grateful to be part of this transformative study with the Longaker lab! 🙏🙏🙏 www.sciencedirect.com/science/arti... STAY TUNED for more in IBD damage from the #Naiklab

New York leads in science & medicine but without state investment, we risk losing talent, cures, jobs, & billions in economic return. Every $1 California invested in biomedical research returned $4 to the state economy. This isn’t just science—it’s smart economics: www.cirm.ca.gov/our-impact/

She’s got her white coat, so now @ananya-p.bsky.social is an official PhD student @sinaiimmuno.bsky.social ! That’s how that works, right? More #gdTcell magic to come! 😁

MARK YOUR CALENDARS 🗓️✏️ On Tuesday, Sept 30th, 10am, host Dr. Hongzhen Hu is excited to welcome @hopkinsmedicine.bsky.social's Dr. Xinzhong Dong to the #BrainBodyResearchInstitute Seminar Series. NOT TO MISS! Register Now ➡️ tinyurl.com/ykky7sf2

The Empire State can’t afford to fall behind. A group of scientists is launching NY-CURES to fight for state and city level investment in research.✊ 📢 Sign up & show Albany we stand UNITED for science. 👉 www.nycures.org @miriammerad.bsky.social @bogunoviclab.bsky.social #AdvocateForScience #NYCURES

Join us tomorrow to build power for our scientific community - whether you are a scientist or an ally! Learn more about how to get involved with Stand Up For Science, and register for our ACTION HOUR! REGISTER link 🔗 in bio!

Scientific writing and publishing can be confusing for early career scientists and graduate students. I am an experienced writer, peer reviewer, and editor, and I'm here to help with a free online crash course!

Good news! #BlackInMicro Week returns Oct 14 - Oct 16, have you registered yet? linktr.ee/BlackInMicro#BlackInMicro(see link in bio)

There’s more than one way to do science 🧠💼 Join us for #BlackInNeuroAltCareers: Beyond the Bench at #BINW25 — featuring Black scientists thriving in tech, policy & beyond. 🗓 Sept 11 | 🕒 3–4 PM ET #5YearsOfBIN

Like a helpful macrophage, we’re determined to remove the pathogens & cancerous cells and then repair the tissue damage 😎

🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀 Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities. Sign up. Stay informed. Join the movement: www.nycures.org/

🚨 New article! Our study "Human monoclonal antibodies protect against death caused by mpox" is now published: 👉 www.cell.com/cell/fulltex... [1/9]

www.mountsinai.org/about/newsro... @sinaiimmuno.bsky.social

Our researchers Samir Parekh, Joshua Brody & Patrick Brunner report the first-ever targeted therapy for a rare, aggressive T-cell lymphoma triggered by CAR T treatment—published @nejm.org. The patient, initially treated for myeloma, is now in remission from both cancers. www.nejm.org/doi/full/10....

🚨 New Publication!!! I’m thrilled to share our latest study, “Clonotype-Enriched Somatic Hypermutations Drive Affinity Maturation of a Public Human Antibody Targeting an Occluded Sarbecovirus Epitope”. www.cell.com/cell-reports... [1/4]

Think that this is cool biology? We agree. Love 20+ color flow? Are you within 2-3 years of your PhD and are looking for a postdoc? We're hiring @sinaiimmuno.bsky.social 😁 ⬇️

🌏🍰!

'The language of the immune system appears to be largely dominated by chemical (that is, molecular) sensing (...)The nervous system, by contrast, recognizes light, sound, pressure, temperature, smell, and pain, and thus is adept at both physical & molecular sensing' www.nature.com/articles/s41...

🚨 AAI is proud to announce the launch of the AAI RESTORE Grants Program, an $8M emergency funding initiative to support scientists whose immunology-focused federal research grants were abruptly terminated or frozen in 2025. 🔗 ow.ly/rwMU50Wy3Mp #AAIRESTORE

Attention science and health communicators: We are hosting our first informational session dedicated to helping you share about infection-associated chronic illnesses like Long COVID, ME/CFS, and post-treatment Lyme disease syndrome. Reach out to [email protected] for more info!