Meet @bhavyasighs.bsky.social, a PhD student co-mentored by @neoviral.bsky.social & @brownlab1.bsky.social. Her research applies functional spatial genomics to understand how repeat elements shape the tumor immune microenvironment, reflecting the collaborative science at ❤️ of discovery in PrIISM.

🌟 In a month, the Hegde Laboratory opens at @einsteinmededu.bsky.social . While this marks the culmination of more than a decade of collaborative research with exceptional mentorship, it also represents an exciting new chapter in our collective quest for the development of next-gen myeloid drugs.

How many immunologists do you know? Meet the people behind the science in our new #MeetThePrIISM video series. ⭐ Episode 1: Jared Weiler, who is researching how the gut microbiome in patients with inflammatory bowel disease can cause trouble elsewhere like inflammation in 🦴🧠🫀&💪.

📣 We’re hiring! Our lab at Mount Sinai is looking for an experienced clinical coordinator to contribute to our #IBD translational studies. If you’d like to expand your translational research skills with a dynamic team, apply below. @sinaiimmuno.bsky.social careers.mountsinai.org/jobs/3037038...

We hosted our first Immunotherapeutics retreat recently, bringing together faculty to spotlight the most promising translational therapies and define where we can accelerate impact. A day focused on turning beautiful science into effective interventions.

DEADLINE TOMORROW ➡️ April 5th! Calling all NYC teachers! Would you like to join @mountsinainyc.bsky.social’s Summer Research Program for Science Teachers? Work in the labs, gain hands-on experience in science content, communications & teaching. APPLY NOW 👉 form.jotform.com/mssmneur0/20...

PhD Defense of Moataz Noureddine, today 2 PM EST. Join us in person in the Goldwurm auditorium at Mt Sinai or virtually mssm.zoom.us/j/7403277880. @sinaiimmuno.bsky.social

Last chance to SIGN UP FOR FREE and hear the latest on immune aging and immunotherapy to extend healthspan from the following founders in the field, online, all welcome, Mar 23 - 25: www.eventbrite.com/e/internatio...

🪩 NEW 🪩 in @aacrjournals.bsky.social Cancer Discovery by @michelletran9.bsky.social @bhardwajlab.bsky.social inflammation in the blood is linked to tumor macrophages that shut down T cells and limit immunotherapy response > new ways to improve bladder cancer therapy: aacrjournals.org/cancerdiscov...

🧬 What happens to regulatory T cells in inflammation? At the #DayofImmunology 2026 webinar, Joris van der Veeken explores how inflammatory environments shape Foxp3 and Treg identity. Join the conversation on April 29. 🔗 https://loom.ly/q1XCaxA#DayofImmunology #DOI2026 #ImmunologyWithoutBorders

Looking for inspiration for #DayofImmunology 2026? Our 2025 Award winners led wide-reaching campaigns, from public lectures to creative outreach and social media engagement. Your society could be next. Apply by May 18: https://loom.ly/yWRSIP0#DayofImmunology#DOI2026 #ImmunologyWithoutBorders #RegulatoryTcell

At Immunoschool, Eicke Latz will discuss targeting inflammasomes, the innate immune sensors linking lifestyle exposures - from Western diet to metabolic stress - to the chronic inflammation that impacts healthspan. Hear more at the online Immunoschool Mar 23 - 25: www.eventbrite.com/e/internatio...

Join us at the 🌏 Immunoschool Mar 23 - 25 🌇 EST to hear more from John Sedivy about how retrotransposons—ancient elements in our genome—shape immune aging and activate nucleic-acid sensing pathways and inflamaging, opening up new therapeutic opportunities. ✍️ FREE www.eventbrite.com/e/internatio...

Like to prep for class? In @nataging.nature.com Dr Merad lays out a key concept in immune aging: protective tissue-resident macrophages are replaced by inflammatory BM–derived macs, driving tissue decline and cancer risk. Restoring TRMs may be central to healthy aging: www.nature.com/articles/s43...

Researching immune aging means playing the long game. Lifespan & healthspan science demands longitudinal human studies to uncover what drives resilience vs decline. Hear how from NIA Scientific Director Luigi Ferrucci at Immunoschool. Free registration: www.eventbrite.com/e/internatio...

At Immunoschool, @gitlinlabmsk.bsky.social will show how VEXAS syndrome is reshaping our understanding of immune aging, late-onset inflammatory disease & new routes to immunotherapy. A powerful 🔗 between clonal hematopoiesis & systemic inflammation. Register FREE: www.eventbrite.com/e/internatio...

VEXAS syndrome is a newly discovered multisystemic disease affecting most organs. A Review provides a comprehensive overview of VEXAS syndrome, including the disease's discovery, diagnosis, and treatment: spkl.io/63321AvBXS

"Cross-Organ Neuroimmunology of Behavior". Xuanming Guo and I discuss a new framework that reconceptualizes behavior as an emergent property of a distributed, brain-body neuroimmune network. lnkd.in/eihqZ_ay. @sinaiimmuno.bsky.social @sinaibrain.bsky.social

When immune cells go senescent, the whole body may follow. But next generation immunotherapies like CAR-T cells and vaccines targeting senoantigens could help us fight back. Don't be a 🧟‍♀️ and 😴 on this opportunity to hear how we can target senescence: FREE sign-up: www.eventbrite.com/e/internatio...

The rules of immunity are different in early life! Lead author Dr. Yue Xing finds that early life DCs sense allergens and trigger inflammation directly in skin. This in-situ activation state emerges from a developing HPA and low glucocorticoids. #Naiklab @nature.com www.nature.com/articles/s41...

In @cp-cancercell.bsky.social, @brownlab1.bsky.social & @miriammerad.bsky.social review how tumor macrophages shape cancer and their plasticity enables new bioengineering approaches to block tumor-promoting signals or reprogram them into tumor-fighting cells. 🧐 www.sciencedirect.com/science/arti...

Still ⏰ to sign up for 3 days of cutting-edge science on how aging reshapes the immune system and interventions to extend healthspan: Register FREE: www.eventbrite.com/e/internatio... Learn about Immunoschool from @miriammerad.bsky.social in this interview reports.mountsinai.org/article/grad...

Masterclass from Dan Puleston on metabolic control of aging ! @sinaiimmuno.bsky.social @miriammerad.bsky.social Fundamental shift in how we think of tissular aging– bioavailability of amino acids will dictate niche repopulation and mac fitness, in turn maintaining function. 🤯 #KSMyeloid26

📝 by @drshrutinaik.bsky.social exemplifies our principle: one immune system, different diseases, shared solutions. Hyper-reactive DCs in infant skin trigger eczema and may drive later asthma and food allergy ⏩ distinct diseases with shared biology & prevention targets. www.nature.com/articles/s41...

What do 🍓🍓🍓 have to do with aging? Check out the Immunoschool program and see if you can figure out the 🍓related topic, inspired by research from @mattyousefzadeh.bsky.social and others on immune-driven tissue decline and new ways to slow, halt or even reverse it. PROGRAM: immunoschool.org

Preserving 🧠 function helps lifelong learners like scientists keep discovering, mentoring and sharing decades of insight with those who come next. Tony Wyss-Coray will explore how immune factors shape 🧠 aging and resilience in the Immunoschool. Program: immunoschool.org Register: lnkd.in/e3NGpYHW

What if aging begins in the youngest immune cells? Emmanuelle Passegué reveals how changes in hematopoietic stem cells drive declining immunity, inflammaging & disease risk, and how restoring them could rebuild resilience. Program: immunoschool.org Register FREE: www.eventbrite.com/e/internatio...

Guido Kroemer joins the 2026 Immunoschool to highlight the hallmarks of immune aging and how they drive decline. Aging hallmarks—from genomic instability to inflammaging—are interconnected & potentially targetable. See what's on immunoschool.org FREE to register www.eventbrite.com/e/internatio...

The immune system profoundly shapes aging as it interacts with every organ. New single-cell & spatial tools now map where this relationship breaks down and where interventions support healthy longevity. More @ Immunoschool Program: immunoschool.org Register (free): www.eventbrite.com/e/internatio...

FREE registration is now open for this year’s International Immunoschool on IMMUNE AGING: ✍️ www.eventbrite.com/e/internatio... From mechanism to translation, there’s something for every career stage. Explore the program here: 🧐 immunoschool.org First speaker is @miriammerad.bsky.social...

📣 Immunoschool 2026 is open for registration 📣 Explore how immunotherapy can promote healthy longevity, from targeting senescent cells to rejuvenating exhausted immunity and reducing inflammaging. FREE, online March 23–25. Program: immunoschool.org Register: www.eventbrite.com/e/internatio...

Preprint: Targeting Neoantigens Conserved Across Organs and Species Overcomes Tumor Immune Escape @bhardwajlab.bsky.social @sinaiimmuno.bsky.social papers.ssrn.com/sol3/papers....

I am thrilled to announce that our latest paper is out now in @cp-cancercell.bsky.social! 1/n www.sciencedirect.com/science/arti...

New **RESOURCE** in @natcancer.nature.com - a landmark single-cell Immune Atlas of multiple myeloma—1.3M+ bone marrow cells from 337 patients. Led by the Immune Atlas Consortium with major contributions from Sacha Gnjatic, @edgargk.bsky.social & HIMC profiling teams 🧐 www.nature.com/articles/s43...

Our paper is out in @pnas.org Big congrats to @jdllkss.bsky.social , and huge thanks to @belkaidlab.bsky.social for the tremendous support. We explore how sensory neuron hyperinnervation regulates itch. @sinaiimmuno.bsky.social @sinaibrain.bsky.social @Dermatology at Mount Sinai.

🎁 Happy holidays from our laboratory to yours. 🎁 Here’s to standing up for science and to a more peaceful and kinder year ahead!

🚨 REVIEW 🚨 Amir Horowitz & Peter Heeger in @natrevneph.nature.com highlight how diverse NK cells in the kidney support immune surveillance but also drive injury in many diseases and contribute to transplant damage, with high-resolution profiling revealing new therapeutic targets. 🧐 rdcu.be/eUgor

Paper out now in @natbiotech.nature.com by @yizhoudonglab.bsky.social describing new LNP mRNAs for combatting bacterial infections… helping the immune system clear the pathogens while limiting tissue damage…

For an expert opinion on the recent report that mRNA COVID vaccines may help immune checkpoint blockade work in patients with advanced lung cancer and metastatic melanoma, read this News & Views in @natrevclinonc.nature.com by Sacha Gnjatic FREE >>> rdcu.be/eQYcu

In Dermatology Times, @itchdoctor.bsky.social highlights that inflammation is a common thread across diseases throughout the body. Studying how it goes awry in one organ—like the skin—can reveal why it misfires elsewhere. www.dermatologytimes.com/view/brian-k...

📣 NEW STUDY 📣 @cp-immunity.bsky.social by Maria Lafaille's lab shows how long-lived IgE-producing plasma cells survive & sustain allergy without continued allergen exposure: maturing in spleen & bone marrow with a unique survival program that resists cell-death signals 🧐 www.cell.com/immunity/abs...

Excited to share our LongTrack study out in @natmicrobiol.nature.com today! Fecal microbiota transplant (FMT), donor 💩 => patients' gut, is an effective treatment for recurrent C. difficile infection & is being evaluated for Inflammatory Bowel Diseases (IBD) & other conditions 1/ 📄 rdcu.be/eL8mR

Also tomorrow, Cindy Xintong Li from the University of Oxford will present a preprint about how TCR activation impairs CAR-T cytotoxicity against separate target cells. @kischober.bsky.social www.biorxiv.org/content/10.1...

Tomorrow, Annie Khamhoung from Mt.Sinai will present a pre-print on the role of brain infiltrating T-cells in microglial dysregulation and neuronal loss following subarachnoid haemorrhage. @ElisaEzanier @MarioNegriIRCCS www.biorxiv.org/content/10.1...

Our new review in @natbiomedeng.nature.com is out! RNA-loaded lipid nanoparticles (LNPs) have huge potential—but their strong liver and immune cell uptake has mostly confined them to vaccines and liver therapies. We explore how to move beyond those limits. free to read 🔗 rdcu.be/eLxGs

Immunotherapy researcher Miriam Merad from Icahn Mount Sinai says the reason that cancer research has slowed is because of funding issues, which is something taxpayers don’t have to accept. “We fight for patients, we fight for science, and we have to fight for progress.” #STATSummit

Add your name ✍ at www.nycures.org so Albany sees 10,000 scientists calling for the future of biomedical research to be built right here in New York. Our first email to members goes out soon—introducing the statewide biomedical institute we’re proposing and how you can help power it forward.

Looking forward to this live episode of @microbetv.bsky.social with my dear friend and rockstar immunologist @diehllab-mskcc.bsky.social #holidayfun #immune100

Wondering what *exactly* we’re up to? Our first coalition email is about to go out—introducing the statewide biomedical institute we’re proposing and how you can help power it forward THIS WEEK! Sign up now so you don’t miss it: www.nycures.org/

Sleep is very good for the immune system!