📢Don't miss this recently published @natcancer.nature.com Article! ✒️By Housheng Hansen He, Xin Xu and colleagues 🔗 www.nature.com/articles/s43...

❄️Our January Issue is out! Featuring: ☑️Review on GBM immunity ☑️immune atlas in multiple myeloma ☑️tumor microbiome in head & neck cancer ☑️MEK–RAF molecular glue against RAS/BRAF-mutant cancers ☑️atypical EMT ☑️CheckMate 77T phase 3 trial in patients with NSCLC and more! www.nature.com/natcancer/vo...

🌟New Perspective at Nature Cancer Read about the recent advances in spatial omics and computational models that inform the classification and clinical relevance of cellular neighborhoods in cancer. by Kai Tan and colleagues @kaitanlab.bsky.social 🔗 www.nature.com/articles/s43...

Our editor Heathcliff Dorado Garcia will be attending Spotlight on the #CancerCell: Vulnerabilities for Therapy, this January in Cary. If you want to connect with him, you can reach him per email! @keystoneSymposia.bsky.social keysym.us/KSCancerCell26 #KSCancerCell26

New Perspective to read at Nature Cancer Learn about the current clinical and preclinical evidence of the effects of GLP-1 medicines on cancer outcomes and their mechanism in cancer cells and the TME. ✏️Julian M. Yabut & @danieljdrucker.bsky.social www.nature.com/articles/s43...

⭐New Article at Nature Cancer Chen et al. report the design and characterization of a systemically injectable oncolytic virus with tumor-targeting and low-immunogenic properties, engineered to induce tumor cell pyroptosis under local mild hyperthermia. www.nature.com/articles/s43...

🚨Don't miss this window-of-opportunity phase 2 RCT now published @natcancer.nature.com: 'Evaluating progesterone receptor agonist megestrol plus letrozole for women with early-stage estrogen-receptor-positive #breastcancer' ✒️By Richard Baird and colleagues 🔗 www.nature.com/articles/s43...

🚨New Article now published at Nature Cancer 'TGFβ induces an atypical #EMT to evade #immune mechanosurveillance in #lungadenocarcinoma dormant #metastasis' ✏️By Joan Massagué and colleagues 🔗 www.nature.com/articles/s43...

📣Check out this Article published at Nature Cancer 'The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers' ✏️By Jeffrey Ecsedy and colleagues 🔗 www.nature.com/articles/s43...

🎆New year, new papers at Nature Cancer! The amount of tumor bacteria is now shown to influence immunotherapy outcomes in head and neck cancer in two papers out today: 🔗 www.nature.com/articles/s43... 🔗 www.nature.com/articles/s43... With the associated N&Vs: www.nature.com/articles/s43...

🚨New Clinical Outlook published as part of the 2025-in-review Nature Cancer content! ✏️By Sandra Misale 'The evolving landscape of RAS-targeted therapies' 🔗 www.nature.com/articles/s43...

⭐Check out this Comment published in the 2025 year-in-review @NatureCancer Focus Issue ✏️By Michelle Monje & Frank Winkler 'Key developments in the cancer neuroscience field' 🔗 www.nature.com/articles/s43...

Take a look at this Article now out at Nature Cancer! ✏️By Christophe Quéva, Francisco Quintana and colleagues 'Retargeted oncolytic viruses engineered to remodel the tumor microenvironment for glioblastoma immunotherapy' 🔗 www.nature.com/articles/s43...

🚨Check out this Technical Report from Nature Cancer ✒️By Tieliang Gong, Chen Li, Mireia Crispin-Ortuzar and colleagues 'SMMILe enables accurate spatial quantification in digital pathology using multiple-instance learning' 🔗 www.nature.com/articles/s43...

🚨Nature Cancer’s 2025 In Review Focus is here! Discover the year’s most impactful developments in cancer research and oncology, with insights from leading experts and curated highlights from top studies. www.nature.com/collections/...

Characterization of the tumor microbiome of brain metastases and glioblastoma reveals tumor-type-specific and location-specific microbial signatures www.nature.com/articles/s43...

🚨New article published at Nature Cancer Using multiple visualization and profiling methods, Gigi et al. characterize the microbiome diversity of 322 brain tumors including brain metastases and glioblastomas. www.nature.com/articles/s43...

New article published @NatureCancer ! 'Spatiotemporal control of SMARCA5 by a MAPK–RUNX1 axis distinguishes mutant KRAS-driven pancreatic malignancy from tissue regeneration' ✏️By Charles David, Mo Chen and colleagues 🔗 www.nature.com/articles/s43...

Article now published @NatureCancer ! 'Cryoablation plus sintilimab and lenvatinib in advanced or metastatic intrahepatic cholangiocarcinoma: a phase 2 trial' ✒️By Ye Li, Peng Wang and colleagues 🔗 www.nature.com/articles/s43...

🍂In case you haven't yet done so, check out our October issue now! 🔗 www.nature.com/natcancer/vo...

Tao et al. show that SCRN1 acts as a scaffold to facilitate GPX4 phosphorylation by STK38, thereby preventing chaperone-mediated autophagy of GPX4 and subsequent ferroptosis in patient-derived organoids and mouse models for hepatocellular carcinoma. www.nature.com/articles/s43...

🚨Don't miss this Resource published now at Nature Cancer, as part of the #HTAN initiative! 'A cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinoma' ✏️By Alexander Tsankov and colleagues 🔗 www.nature.com/articles/s43...

🚨Check out this Article published at Nature Cancer! 'Aberrant expression of SLAMF6 constitutes a targetable immune escape mechanism in acute myeloid leukemia' ✏️By Thoas Fioretos, Carl Sandén and colleagues 🔗 www.nature.com/articles/s43...

Save the date! We are hosting the webinar "Inflammatory cell death and anti-tumor immunity". Join our speakers Dmitri Krysko, Judy Lieberman, Lorenzo Galluzzi and Pascal Meier @deadoc80.bsky.social @meierlabicr.bsky.social 📅 Tuesday 14th Oct 2025 ⏰ 16.00 PM (GMT+1) cassyni.com/events/QAERn...

🚨Check out this article published now at Nature Cancer! ✏️By Scott Lowe and colleagues 'SMAD4 induces opposite effects on metastatic growth from pancreatic tumors depending on the organ of residence' 🔗 www.nature.com/articles/s43...

🍂Our September issue is OUT NOW! Featuring, among others: - A Perspective on #drugconjugates - #immunotherapy studies - research on GBM invasion - method for #singlecell analyses of #CTCs 🔗 www.nature.com/natcancer/vo...

Check out this recent Review published at Nature Cancer! ✒️By Dario Neri and colleagues 'Past, present and future of #drugconjugates for #cancertherapy' 🔗 www.nature.com/articles/s43...

🚨Our Senior Editor Elena Skourti will be at the #ESMO Molecular Analysis for Precision Oncology Congress over the next two days. Find her and talk to her about your research!

Shao et al. developed an MRI–pathology-based foundation model to assess the pathology of prostate cancer for diagnosis and grading of tumors. The model is noninvasive and outperforms current pathological assessments. www.nature.com/articles/s43...

🤩Just started your lab as a #newPI in cancer research? Let us know about your exciting news, reach out to Nature Cancer -we'd love to connect with the new generations 👀

Resource article published now @NatureCancer 'Spatiotemporal analyses of the pan-cancer single-cell landscape reveal widespread profibrotic ecotypes associated with tumor immunity' ✒️By Qiu Wu, Chenfei Wang and colleagues 🔗 www.nature.com/articles/s43...

Article now ONLINE @at Nature Cancer! 'A sphingolipid-derived paclitaxel nanovesicle enhances efficacy of combination therapies in triple-negative breast cancer and pancreatic cancer' ✏️By Jianqin Lu and colleagues 🔗 www.nature.com/articles/s43...

📢New Article now published at Nature Cancer! 'Colorectal cancer cells hijack a brain–gut polysynaptic circuit from the lateral septum to enteric neurons to sustain tumor growth' ✏️By Tian-Ming Gao, Jian-Ming Li and colleagues 🔗 www.nature.com/articles/s43...

⭐️New Article published at Nature Cancer! 'Evolutionary trajectories of IDH-mutant astrocytoma identify molecular grading markers related to cell cycling' ✒️By Wies Vallentgoed and colleagues 🔗 www.nature.com/articles/s43...

🚨New REVIEW article online at Nature Cancer! 'Prospects for ferroptosis therapies in cancer' ✒️By Jessalyn Ubellacker & Scott Dixon 🔗 www.nature.com/articles/s43...

Our August issue is OUT NOW! ☀️ Check it out here: 🔗 www.nature.com/natcancer/vo... ⭐️Featuring: - review on #nanotechnology for immuno-oncology - review on #ferroptosis for #cancertherapy - AI in clinical oncology - cancer #cachexia - #immunotherapy clinical trial

🌟Review online! Dotti and colleagues review CAR-engineered cell-based cancer therapy and overview its transition for solid tumors from CAR-T to CAR-engineered innate immune cells, discussing strengths and limitations for clinical application. www.nature.com/articles/s43...

🚨Don't miss the July issue of Nature Cancer! Check it out here: 🔗 www.nature.com/natcancer/vo... Featuring: ⭐️Review on clonal hematopoiesis in cancer ⭐️Review on CAR engineering for cancer therapy ⭐️immunotherapy ⭐️AI for tumour classification ⭐️single-cell analyses in B-ALL

🚨ARTICLE now published at Nature Cancer ! ✏️By Valsamo Anagnostou and colleagues 'Combination of pembrolizumab and radiotherapy induces systemic antitumor immune responses in immunologically cold non-small cell lung cancer' 🔗 www.nature.com/articles/s43...

📢New Article published at Nature Cancer! ✒️By Christopher Klebanoff and colleagues 'CAR-engineered lymphocyte persistence is governed by a FAS ligand–FAS autoregulatory circuit' 🔗 www.nature.com/articles/s43...

Our Senior Editor Elena Skourti is attending the AACR Special Conference in Artificial Intelligence & Machine Learning this week. If you are there, find her and connect!

Thanks Nature Cancer for the chance to reflect on some factors that led me to study cancer metabolism. For the trainees and other young scientists: the critical events that shape your career might not be obvious while they are happening. Keep an open mind and trust your instincts. rdcu.be/evi4I

🌟Review at Nature Cancer Chalabi and colleagues summarize the current clinical landscape of neoadjuvant immunotherapy in solid tumors www.nature.com/articles/s43...

Will it be a turning point? I recently came back from a research sabbatical funded by @fwovlaanderen.bsky.social & #KULeuven in the lab of @mafdawson.bsky.social @petermaccc.bsky.social and I am happy to share my experience @natcancer.nature.com www.nature.com/articles/s43... @vib-ccb.bsky.social

Out today! www.nature.com/articles/s43...

🚨 Clinical Trial published at Nature Cancer! David Cibula and colleagues report on the final outcome of the SENTIX international trial, assessing sentinel LN biopsy without systematic pelvic lymphadenectomy in early-stage cervical cancer. 🔗 www.nature.com/articles/s43...

🚨New Article Alert from Nature Cancer ! 'Self-amplifying NRF2–EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer' ✏️ By Michael Karin and colleagues 🔗 www.nature.com/articles/s43...

📢Another Article ONLINE at Nature Cancer! 'Profiling antigen-binding affinity of B cell repertoires in tumors by deep learning predicts immune-checkpoint inhibitor treatment outcomes' ✒️By Junzhou Huang, David Gerber, Tao Wang and colleagues 🔗 www.nature.com/articles/s43...

🚨New Article ONLINE at Nature Cancer! 'Multipotent lineage potential in B cell acute lymphoblastic leukemia is associated with distinct cellular origins and clinical features' ✒️ By John Dick, Charles Mullighan and colleagues 🔗 www.nature.com/articles/s43...

📢We’ve partnered with MD Anderson to explore recent breakthroughs in understanding the tumor ecosystem and how its various components influence cancer development, progression, diagnosis, and treatment. Learn more and save your seat! 🔗 go.nature.com/44cJT9Z