Check out “Frameshift,” a Q&A series in which neuroscientists with nontraditional careers discuss their work and how they made the transition away from the lab. In the first entry of the series, @shariwiseman.bsky.social shares how she went from the bench to science publishing. bit.ly/4rZkk5S

Don't sleep on our December issue! www.nature.com/neuro/volume...

Connectome caricatures remove large-amplitude coactivation patterns in resting-state fMRI to emphasize individual differences www.nature.com/articles/s41...

Laser-engineered PRIME fiber for panoramic reconfigurable control of neural activity www.nature.com/articles/s41...

Parietal cortex output neurons form a specialized population code that enhances the propagation of information to a downstream target and potentially improves the accuracy of decision-making www.nature.com/articles/s41...

Chief Editor Shari Wiseman @shariwiseman.bsky.social will be at the @springernature.com booth (#2220, look for the picture of a woman rock-climbing) from 2-4 today and from 10-12 tomorrow. Come stop by! #SfN2025

TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD www.nature.com/articles/s41...

Chief Editor Shari Wiseman @shariwiseman.bsky.social will be at the @sfn.org meeting! She'll be at the @springernature.com booth (#2220) from 2-4 pm on Sunday and Tuesday, and from 10 am-12 pm on Monday and Wednesday. If you’d like to set up a one-on-one meeting, please email her. #SfN2025

Attentional failures during wakefulness after sleep deprivation are tightly orchestrated in a series of brain–body changes, including neuronal shifts, pupil constriction and cerebrospinal fluid (CSF) flow pulsations @lauradata.bsky.social @ziy027.bsky.social www.nature.com/articles/s41...

🥳Please join us in welcoming Ana Uzquiano @uzquianoa.bsky.social to our editorial team! Ioana is handling transcriptomics, neurodevelopment, and cellular and molecular neuroscience. She's based in the Madrid office.

The brain’s wake-to-sleep transition follows bifurcation dynamics with a distinct tipping point preceded by a critical slowing down www.nature.com/articles/s41...

Connectome datasets alone are generally not sufficient to predict neural activity. However, pairing connectivity information with neural recordings can produce accurate predictions of activity in unrecorded neurons www.nature.com/articles/s41...

Longitudinal measures of monkey brain structure and activity through adolescence predict cognitive maturation @cconstan.bsky.social www.nature.com/articles/s41...

Large-scale chromatin accessibility profiling (ATAC-seq) of neurons and non-neurons from 2 human neocortical regions from 469 unique donors, comprising controls and individuals diagnosed with schizophrenia and bipolar disorder www.nature.com/articles/s41...

Cortical and subcortical mapping of the human allostatic–interoceptive system using 7 Tesla fMRI www.nature.com/articles/s41...

Our November issue is now live! www.nature.com/neuro/volume...

Characterization of the circadian translatomes of astrocytes and microglia in mouse cortex in the setting of amyloid pathology or aging, revealing cell and disease-specific circadian reprogramming of neurodegeneration-related pathways www.nature.com/articles/s41...

A pair of papers on how TDP-43 loss in ALS/FTD causes changes in mRNA polyadenylation This one from Aaron Gitler's group www.nature.com/articles/s41...

Leptin-sensitive neuronal subpopulations in the lateral hypothalamus enable adaptive fulfillment of vital needs despite anxiogenic conditions www.nature.com/articles/s41...

Oxytocin modulates respiratory heart rate variability through a hypothalamus–brainstem–heart neuronal pathway @julie.buron.bsky.social @inmed.bsky.social @insermpacacorse.bsky.social [email protected] www.nature.com/articles/s41...

🥳Please join us in welcoming Ioana Marin to our editorial team! Ioana is handling neuroimmunology and cellular and molecular neuroscience. She's based in the NYC office.

High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN), a common target for Parkinson’s disease, activates afferent axons while inhibiting STN neurons www.nature.com/articles/s41...

A noninvasive, CSF-specific MRI technique that enables detailed in vivo measurement of CSF mobility in humans, down to the level of perivascular spaces located around penetrating vessels www.nature.com/articles/s41...

C9orf72 mutations impair immune activation in ALS, highlighting key differences in the cellular and molecular pathways underlying sporadic and genetics forms of the disease @mancusorenzo.bsky.social @c9laura72.bsky.social @baukje-bij.bsky.social @cmn-vib.bsky.social www.nature.com/articles/s41...

Nature Neuroscience is happy to now offer Transparent Peer Review, in which authors can choose for us to publish details about the peer review process (including reviews, rebuttal letters, and editorial decision letters). More info at the link below: www.nature.com/neuro/editor...

Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of mouse and human brain function @adamqbauer.bsky.social @jordacular.bsky.social @realjoshsiegel.bsky.social @oliverk28.bsky.social www.nature.com/articles/s41...

Astrocytic Ca2+ prevents synaptic depotentiation by limiting repetitive activity in dendrites during motor learning @baolinglai.bsky.social www.nature.com/articles/s41...

Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape www.nature.com/articles/s41...

Muscle-derived miR-126 regulates TDP-43 axonal local synthesis and NMJ integrity in ALS models www.nature.com/articles/s41...

Want to close the gender gap in research? Start with the data. Our Springer Nature report: Closing the Gender Gap highlights where change is needed most — and how you can be part of it. Read the report: spklr.io/63324ByG4y

A single dose of #psilocybin induces a rapid and sustained reversal of both mechanical allodynia (pain) and anxiodepression-like states in adult male and female mice www.nature.com/articles/s41...

Our October issue is now live! www.nature.com/neuro/volume...

Characteristic facial features in mice simultaneously encode not only currently used decision variables but also independent and unexpressed ones, and these features partially originate from neural activity in the secondary motor cortex @fannycazettes.bsky.social www.nature.com/articles/s41...

Hormonal milieu influences whole-brain structural dynamics across the menstrual cycle using dense sampling in multiple individuals @carinaheller.bsky.social, @uni-jena.de, @umn-midb.bsky.social, @icsantabarbara.bsky.social www.nature.com/articles/s41...

An inhibitory pathway from the medial septum (MS) to the subfornical organ (SFO) that is involved in the control of anticipatory drinking behavior in mice www.nature.com/articles/s41...

Temporal integration throughout the human auditory cortex is predominantly locked to absolute time and does not vary with the duration of speech structures such as phonemes or words @samnorman-haignere.bsky.social @urneuroscience.bsky.social @urochester.bsky.social www.nature.com/articles/s41...

The abstract submission deadline for our three-day conference on brain energy metabolism is Oct. 3! Join experts such as @rioslab.bsky.social and @carmensandi10.bsky.social to share findings and exchange ideas. Learn more: go.nature.com/4p4rqV9 #Neuroskyence #Academicsky #STEMconference

A pair of papers on using holographic optogenetics and compressed sensing for connectomics: Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing www.nature.com/articles/s41...

Neurons in mouse primary visual cortex that respond emergently to illusory contours drive pattern completion www.nature.com/articles/s41...

Our Chief Editor Shari Wiseman @shariwiseman.bsky.social will be at the Chinese Neuroscience Society meeting in Xi'an next week. Send her an email if you'd like to meet to talk about your work! #CNS2025

Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery www.nature.com/articles/s41...

Review: A neural manifold view of the brain www.nature.com/articles/s41...

Grid cells do not operate as a global positioning system but rather estimate position within multiple local reference frames www.nature.com/articles/s41...

The activations of large-scale cortical functional networks are organized in an inherently cyclical manner, ensuring periodic activation of essential cognitive functions @matsvanes.bsky.social @oxcin.bsky.social @oxfordpsychiatry.bsky.social @ox.ac.uk www.nature.com/articles/s41...

Allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells www.nature.com/articles/s41...

Check out our September issue! www.nature.com/neuro/volume...

CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes @kampmann.bsky.social @ivlrose.bsky.social www.nature.com/articles/s41...

Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits www.nature.com/articles/s41...

Longitudinal neuroimaging in three adults, followed before and up to 5 years after arm amputation, reveals that amputation does not trigger large-scale cortical reorganization @hunterschone.bsky.social @cibaker.bsky.social @plasticity-lab.bsky.social www.nature.com/articles/s41...

FOXP genes regulate Purkinje cell diversity and cerebellar morphogenesis @nagham-farah.bsky.social www.nature.com/articles/s41...