A pair of papers on using holographic optogenetics and compressed sensing for connectomics: Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing www.nature.com/articles/s41...

Neurons in mouse primary visual cortex that respond emergently to illusory contours drive pattern completion www.nature.com/articles/s41...

Our Chief Editor Shari Wiseman @shariwiseman.bsky.social will be at the Chinese Neuroscience Society meeting in Xi'an next week. Send her an email if you'd like to meet to talk about your work! #CNS2025

Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery www.nature.com/articles/s41...

Review: A neural manifold view of the brain www.nature.com/articles/s41...

Grid cells do not operate as a global positioning system but rather estimate position within multiple local reference frames www.nature.com/articles/s41...

The activations of large-scale cortical functional networks are organized in an inherently cyclical manner, ensuring periodic activation of essential cognitive functions @matsvanes.bsky.social @oxcin.bsky.social @oxfordpsychiatry.bsky.social @ox.ac.uk www.nature.com/articles/s41...

Allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells www.nature.com/articles/s41...

Check out our September issue! www.nature.com/neuro/volume...

CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes @kampmann.bsky.social @ivlrose.bsky.social www.nature.com/articles/s41...

Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits www.nature.com/articles/s41...

Longitudinal neuroimaging in three adults, followed before and up to 5 years after arm amputation, reveals that amputation does not trigger large-scale cortical reorganization @hunterschone.bsky.social @cibaker.bsky.social @plasticity-lab.bsky.social www.nature.com/articles/s41...

FOXP genes regulate Purkinje cell diversity and cerebellar morphogenesis @nagham-farah.bsky.social www.nature.com/articles/s41...

Impaired capillary–venous drainage contributes to gliosis and demyelination in mouse white matter during aging www.nature.com/articles/s41...

Viral reexpression of embryonic transcription factors in postnatal spinal cord motor neurons partially reactivates youthful gene expression and alleviates disease-relevant phenotypes in a mouse model of ALS @emily-rhodes-lowry.bsky.social, @tulsiboots.bsky.social www.nature.com/articles/s41...

Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement @kiahhardcastle.bsky.social @olveczky.bsky.social www.nature.com/articles/s41...

A pancreas–hippocampus feedback mechanism regulates circadian changes in depression-related behaviors www.nature.com/articles/s41...

Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD @junjieguo.bsky.social @yalerna.bsky.social @yaleneuro.bsky.social www.nature.com/articles/s41...

Layer-specific changes in sensory cortex across the lifespan in mice and humans www.nature.com/articles/s41...

Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes @zhoujoeyyi.bsky.social www.nature.com/articles/s41...

Potentiation of mitochondrial function by mitoDREADD-Gs reverses pharmacological and neurodegenerative cognitive impairment in mice www.nature.com/articles/s41...

Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson’s disease www.nature.com/articles/s41...

Serotonergic modulation of the BNST–CeA pathway reveals sex differences in fear learning in mice @friedmanlaboratory.bsky.social, @beckyravenelle.bsky.social, @elikhtik.bsky.social, @neshaburghardt.bsky.social www.nature.com/articles/s41...

Nonhallucinogenic psychoplastogens have antidepressant-like effects and promote neuroplasticity through the same biochemical pathway as classic psychedelics, but don't cause immediate glutamate burst or IEG activation @deolsonlab.bsky.social @ucdavisipn.bsky.social www.nature.com/articles/s41...

A transcriptional analysis of primary microglia from 189 human postmortem brains: 58 healthy aging individuals and 131 with a range of disease phenotypes, including 63 patients representing the full clinical and pathological spectra of Alzheimer's disease www.nature.com/articles/s41...

An integrated single-nucleus and spatial transcriptomics atlas of the human hippocampus www.nature.com/articles/s41...

Our August issue is now online! www.nature.com/neuro/volume...

Dopamine dynamics in the nucleus accumbens core reflected decision confidence during evaluation of decisions in an economic foraging task in mice, as well as both past and future value during re-evaluation and change-of-mind @perothwell.bsky.social www.nature.com/articles/s41...

Astrocyte specification in the mouse septum is shaped by both developmental origin and local signals www.nature.com/articles/s41...

Sight of someone potentially infectious causes immune response, research suggests

The connectivity of mouse visual cortex thick tufted layer 5 pyramidal cells, also known as extratelencephalic neurons (L5-ETns), using a 1 mm3 publicly available electron microscopy dataset, part of the MICrONS Project @alleninstitute.org www.nature.com/articles/s41...

Avatars who appear to be sick entering the peripersonal space in virtual reality are anticipated by multisensory–motor areas, activate the salience network, and trigger activation of innate lymphoid cells, mirroring responses seen in actual infections www.nature.com/articles/s41...

📢 The new cross-journal Collection “Lifespan changes in the human brain” with @commsbio.nature.com, @natcomms.nature.com, @natneuro.nature.com, and Scientific Reports is now open for submissions! 📭 🌍 Learn more: www.nature.com/collections/... #Neuroscience #Brain #Lifespan #Neuroimaging

Noradrenergic activation of the BLA promotes the formation of discrete memories of similar events that were experienced close in time, via a miR-134-regulated consolidation process within the dentate gyrus of the hippocampus www.nature.com/articles/s41...

Particularly informative spatial cues produce a higher and narrower bump of activity in the Drosophila head direction system. These informative cues can instruct the remapping of other cues to produce a self-consistent map. www.nature.com/articles/s41...

Voltage imaging in mouse hippocampus reveals that interneurons sharpen memory encoding-activity by increasing the signal-to-noise ratio of pyramidal neuron sensory representations during working memory www.nature.com/articles/s41...

Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy, including postmortem PSP brain samples and a living human brain slice culture model www.nature.com/articles/s41...

We're hiring! Nature Neuroscience is hiring an Associate or Senior Editor with experience in cellular and molecular neuroscience, glia, and genomics to work in our New York or Shanghai office. Applications are due August 19. springernature.wd3.myworkdayjobs.com/en-US/Spring...

Tau PET positivity in individuals (42 cohorts worldwide, N = 12,048) with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex @rikossenkoppele.bsky.social www.nature.com/articles/s41...

The human brain synchronizes visual signals by adjusting axonal conduction speed in the retina—revealing a previously unknown mechanism for precise perceptual timing @anbucci.bsky.social @ffranke.bsky.social @iobswiss.bsky.social www.nature.com/articles/s41...

Stimulating and recording with intracranial electrodes implanted in cortical regions and thalamic nuclei across 4,864 sites in 27 human participants reveals distinct spectral signatures elicited by perturbations of specific brain areas www.nature.com/articles/s41...

Discrete sites in the human insular cortex showed changes of ac vity that predicted later memory recall, while others responded to emo onal content. Smula on of memoryrelated sites showed direct influence over the hippocampus www.nature.com/articles/s41...

Characterizing plaque-associated #microglia (PAM) and non-plaque-associated microglia (non-PAM) in a mouse model of Alzheimer's disease; non-PAM modulate cell population expansion in response to amyloid deposition and rapidly respond to environmental cues www.nature.com/articles/s41...

Neonatal gyrencephalic brains, including humans, harbor an elaborate subventricular zone (the Arc). It contains diverse interneurons from the medial and caudal ganglionic eminences that migrate into the cortex www.nature.com/articles/s41...

Intersectin and endophilin condensates prime synaptic vesicles for release site replenishment @watanabelab.bsky.social www.nature.com/articles/s41...

Ventral telencephalic progenitor maturation is gated by developmental timing, revealing a distinct regulatory logic underlying the development of inhibitory neurons @annrosebright.bsky.social @flo-neuhaus.bsky.social aus.bsky.social, @chr-mayer.bsky.social www.nature.com/articles/s41...

Our July issue is now live! www.nature.com/neuro/volume...

Human thalamocortical connectivity matures along the cortex’s sensorimotor–association axis www.nature.com/articles/s41...

Comment: The brain works at more than 10 bits per second www.nature.com/articles/s41...

Just a reminder about our job opening for someone with cellular/molecular neuroscience experience! The application is due July 8.