🚨 New study: Intranasal H5N1 vaccine shows strong immune response & cross-strain protection. Could this be a game-changer for pandemic preparedness?🦠💉 🔗Published in @natcomms.nature.com: bit.ly/3WJV2u7 #BirdFlu #Vaccines #Research #PublicHealth #MedEd #MedSky

🌍 Inventan un sistema de IA que ayuda a detectar signos de tuberculosis en radiografías pediátricas. Desarrollado por investigadores de la @upm.es y del CIBER-BBN, en colaboración con @isglobal.org, centro con el apoyo de la Fundación "la Caixa". ✏️ @natcomms.nature.com

E. coli can spread as quickly as swine flu, new research reveals. 🦠 For the first time, scientists can predict the rate at which gut bacteria pass between people — a major step towards tackling antibiotic-resistant infections. Read here ⤵️ sanger.ac.uk/news_item/ad...

Beobide-Arsuaga et al. shows that #Projected changes in #InternalClimateVariability are expected to amplify #Heatwave intensity in central and northern #Europe —making these events more severe and less predictable—while dampening the trend in southern #Europe. www.nature.com/articles/s41...

New study looks at the effects of #forestation on #temperature in Europe using #climate model experiments, showing that conversion from coniferous to broadleaved trees in forested areas can provide #cooling for #summer hot extremes. @ethz.ch www.nature.com/articles/s41...

🧬 EMERGENCY SWITCH! 🤯 Bacteria adapt their metabolism to famine in seconds. @uni-jena.de researchers found that 𝘊𝘢𝘶𝘭𝘰𝘣𝘢𝘤𝘵𝘦𝘳 𝘤𝘳𝘦𝘴𝘤𝘦𝘯𝘵𝘶𝘴 use two RNA molecules as molecular switches. An 'RNA sponge' kicks in to ensure survival.

Marine animals play a key role in locking #carbon deep in the #ocean, slowing #climate change. This study finds that fishing has already cut this service in half, with climate change expected to further reduce it in the future. @gaelmariani.bsky.social @oceanicu.bsky.social

Discovery and mechanism of a highly selective, antifungal acetyl-CoA synthetase inhibitor #DrugDiscovery #mycology #Cryptococcus

Chromosome replication and cell division cycles are not synchronized in Staphylococcus aureus, with cells exhibiting two segregated origins of replication at the start of the cell cycle #bacteria #microbiology

Discovery that Munc13-4 promotes breast cancer immune evasion through regulation of PD-L1 sorting in exosomes doi.org/10.1038/s414...

Discovery of ALKBH8 as a direct transcriptional target of β-catenin, and that it mediates intestinal tumorigenesis through regulation of the translation of KRAS in a codon-dependent manner. doi.org/10.1038/s414...

Chromosome replication and cell division cycles are not synchronized in Staphylococcus aureus, with cells exhibiting two segregated origins of replication at the start of the cell cycle #bacteria #microbiology

Discovery and mechanism of a highly selective, antifungal acetyl-CoA synthetase inhibitor #DrugDiscovery #mycology #Cryptococcus

Learn how our hunt for the native structure of top antimalarial target PfATP4🧂led to the discovery of PfABP, an unknown essential binding partner, out now! @natcomms.nature.com 👉 rdcu.be/eLRlH 🦠🔬❄️ A team effort led by @mehsehret.bsky.social & Anurag Shukla @akhilvaidya.bsky.social! #cryoEM #malaria

Song et al. show that the properties of the #AABW largely determine the #AMOC depth and strength across climate states by affecting the routes via which North Atlantic Deep Water returns to the ocean surface. #LGM, #ClimateChange www.nature.com/articles/s41...

Dissecting the fitness effects of a carbapenem resistance plasmid in clinical Enterobacterales using plasmid-wide CRISPRi screens @aliciapcv.bsky.social @jorgesastred.bsky.social @sanmillan.bsky.social @cnb-csic.bsky.social #bacteria #plasmids

In vivo antimicrobial activity of engineered mesoporous silica nanoparticles targeting intracellular #mycobacteria (doxycycline-loaded nanoparticles, zebrafish model of Mycobacterium marinum #infection) @lkremer1.bsky.social#mycobacteria#infection#DrugDevelopment

New study with data from underwater gliders, satellites and numerical simulations shows that #submesoscale motions at #ocean eddy edges pump heat upward, forming “warm rings” in the Lofoten Basin, suggesting a key pathway for #Atlantic water heat loss. www.nature.com/articles/s41...

"You’re at the beginning of your PhD, immersed in your main projects, when your supervisor comes to you with an idea: “Why don’t we try something on the side? Just a little side project”" https://bit.ly/47hsblR

Understanding how a common virus manipulates its host's DNA (Human #cytomegalovirus #HCMV is known to be linked to birth defects and chronic illness) #virology #herpesvirus #chromatin

"You’re at the beginning of your PhD, immersed in your main projects, when your supervisor comes to you with an idea: “Why don’t we try something on the side? Just a little side project”" https://bit.ly/47bs62W

Dissecting the fitness effects of a carbapenem resistance plasmid in clinical Enterobacterales using plasmid-wide CRISPRi screens @aliciapcv.bsky.social @jorgesastred.bsky.social @sanmillan.bsky.social @cnb-csic.bsky.social #bacteria #plasmids

Population structure in a fungal human pathogen is associated with clinical prevalence #Aspergillus flavus @annemakerofhats.bsky.social ‪@ameliabarberphd.bsky.social‬ @rokaslab.bsky.social#Aspergillus #fungi #infection #PopulationGenomics #mycology

New paper finally out on @natcomms.nature.com! Led by first author Maria Dramé with the collaboration of Francisco Garcia, @cbuch.bsky.social and @jytinevez.bsky.social at @pasteur.fr. Early mitochondrial signals in single human macrophages predict later Legionella replication. Link + details👇🧵

New study by Ribes and colleagues shows that incorporating observations from every new year in constrained #projections of forced #warming, improves estimates of the expected warming in response to different #emission scenarios. @cnrs.fr www.nature.com/articles/s41...

5 minutos en @radio5rne.rtve.es para hablar de nuestro último descubrimiento @natcomms.nature.com www.rtve.es/play/audios/... Gracias al gran @cserna.bsky.social y equipazo ARU! @ucm.es @seimc.bsky.social

Results from elephant herpesvirus trial find vaccine to be safe "The world’s first vaccine trial against elephant endotheliotropic #herpesvirus (EEHV) – a leading cause of death in young Asian #elephants – is safe & triggers a strong virus-fighting immune response" www.surrey.ac.uk/news/breakth...

Population structure in a fungal human pathogen is associated with clinical prevalence #Aspergillus flavus @annemakerofhats.bsky.social ‪@ameliabarberphd.bsky.social‬ @rokaslab.bsky.social#Aspergillus #fungi #infection #PopulationGenomics #mycology

New study uses high-resolution #climate model simulations and shows that #GlobalWarming may trigger an abrupt shift towards stronger and more predictable #ENSO cycles, intensifying climate impacts globally. www.nature.com/articles/s41...

In vivo antimicrobial activity of engineered mesoporous silica nanoparticles targeting intracellular #mycobacteria (doxycycline-loaded nanoparticles, zebrafish model of Mycobacterium marinum #infection) @lkremer1.bsky.social#mycobacteria#infection#DrugDevelopment

New paper alert! In this work, published in @natcomms.nature.com we show that a new antibiotic is effective against (r)CDI. www.nature.com/articles/s41...

A study of ~7 million Brazilian births shows that infection with #chikungunya, #dengue or #Zika viruses during pregnancy is associated with increased risk of adverse perinatal outcomes @csthiago.bsky.social#chikungunya#dengue#Zika#viruses #epidemiology #pregnancy

Efficacy of a modified-vaccinia Ankara vaccine as pre- and post-exposure prophylaxis against sexual transmission of #monkeypox virus in a non-human primate model #mpox #vaccines #viruses #virology

Did you know that the #T4SS can also mediate biofilm formation?🧫 A #Crohnsdisease associated E. coli strain carries a hybrid T4SS that drives pilin polymerization and #biofilm formation, leading to enhanced fitness in the gut. Read about it here ⬇️ @natcomms.nature.com #naturecommunications

New featured image on our homepage! https://bit.ly/3W2Vl2T In this paper, Kathryn Everson et al. explore lemur #evolution using a phylogenomic dataset with broad taxonomic sampling, revealing patterns of speciation, extinction, & gene flow https://bit.ly/4hhN596

New publication: #OneHealth approach uncovers emergence and dynamics of Usutu and West Nile viruses in the Netherlands, by @jurrianvanirsel.bsky.social @tjommem.bsky.social and others. #usutuvirus #westnilevirus #ecologicalepidemiology doi.org/10.1038/s414...

New featured image on our homepage! https://bit.ly/4q12LBk In this paper, Kathryn Everson et al. explore lemur evolution using a phylogenomic dataset with broad taxonomic sampling, revealing patterns of speciation, extinction, & gene flow https://bit.ly/4nfw8gU

Efficacy of a modified-vaccinia Ankara vaccine as pre- and post-exposure prophylaxis against sexual transmission of #monkeypox virus in a non-human primate model #mpox #vaccines #viruses #virology

Extremely glad to see this out!! Wonderful work by all the lab, especially @aliciapcv.bsky.social. Don't miss her thread!!

A high-throughput deep sequencing assay to distinguish Plasmodium vivax #malaria lineages For geospatial infection tracking & to distinguish new vs. relapsing infections @sarahauburn.bsky.social @acreme.bsky.social @menziesresearch.bsky.social

One of our top-rated articles on @altmetric.com this past week was published open access in @natcomms.nature.com. Read 'A safe, T cell-inducing heterologous vaccine against elephant endotheliotropic herpesvirus in a proof-of-concept study' here: www.nature.com/articles/s41... #epidemiology #episky

I thought the Aspergillus fumigatus pan-genome was pretty wild when we started this project. Aspergillus flavus said, "hold my beer..." Not only does it have a strong population structure with differences between environmental and clinical strains, only 58%of genes are conserved across the species!

New study by Song et al. highlights a sharp #Warming contrast within the #SouthernOcean: the #Atlantic-Indian sector warms faster than the #Pacific due to #wind-driven heat transport. The contrast is projected to persist, shaping future climate and ocean change. www.nature.com/articles/s41...

A study of ~7 million Brazilian births shows that infection with #chikungunya, #dengue or #Zika viruses during pregnancy is associated with increased risk of adverse perinatal outcomes @csthiago.bsky.social#chikungunya#dengue#Zika#viruses #epidemiology #pregnancy

A high-throughput deep sequencing assay to distinguish Plasmodium vivax #malaria lineages For geospatial infection tracking & to distinguish new vs. relapsing infections @sarahauburn.bsky.social @acreme.bsky.social @menziesresearch.bsky.social

Understanding how a common virus manipulates its host's DNA (Human #cytomegalovirus #HCMV is known to be linked to birth defects and chronic illness) #virology #herpesvirus #chromatin

A 165 Myr record of N and Corg isotopes shows that the N-cycle responds to feedbacks associated with productivity and the changing location of upwelling centers due to continental meander. www.nature.com/articles/s41...

This study shows strong soil moisture–precipitation coupling over ~16% of global land area. www.nature.com/articles/s41...

Experiments and modelling unravel mechanisms of nitrous oxide production from nitrate, the primary nitrous oxide production pathway in oxygen minimum zones. Results highlight the critical role of #microbial interactions in regulating this pathway. #OMZ www.nature.com/articles/s41...

A decade of BGC-Argo and plankton records shows North Pacific heatwaves reshape food webs and trap small particles in midwater, slowing deep-ocean carbon export. Impacts vary by event, underscoring the need for sustained ocean monitoring. @mbarinews.bsky.social @miamirosenstiel.bsky.social