New study presents a #MachineLearning -based emergent constraint that reduces uncertainty in future #climate #warming projections by ~70%. The constraint projections show that an earlier than anticipated exceedance of 2°C warming is more likely. www.nature.com/articles/s41...

New study by @atmos-dynamics.bsky.social and colleagues shows that #ClimateModels overestimate greenhouse gas effects on the interhemispheric #temperature difference, suggesting future #tropical #rainfall shifts may be less severe than projected. www.nature.com/articles/s41...

🔬🤖 How can we explore chemical reactions without guessing the pathway first? Zhang & Piccini introduce Loxodynamics: a deep‑learning approach that uses the skewness of molecular motion to automatically find reaction pathways. www.nature.com/articles/s41... #ScienceSky #CompChem #MachineLearning

New study shows that declining anthropogenic #aerosols can amplify the weakening of the Northern Hemisphere #HadleyCirculation, highlighting the critical role of aerosol reductions in driving #TropicalCirculation changes in the 21st century. www.nature.com/articles/s41...

New study shows that a transition of the #stratospheric polar vortex morphology is an effective precursor of the phase reversal of the “warm Arctic-cold Eurasia” pattern in winter and that #CMIP6 models with complete stratospheric processes can capture this link. www.nature.com/articles/s41...

Chromosome-specific telomere lengths measured in >2,500 All of Us participants reveal arm‑level variation, strong individual differences, and age‑related shortening. #LongReadSequencing enables refined disease‑association analyses. #NatureCommunications #Genetics Read more below 🔗

Ecological partitioning enables phage–antibiotic cooperation in a human Pseudomonas infection #Antibiotics & #PhageTherapy coordinate through ecological & immunologic complementarity rather than direct pharmacologic synergy @scientiff.bsky.social

Ecology and evolution of the nosocomial pathogen Acinetobacter baumannii outside hospital settings: - soil-dwelling colonization of decaying plant material - airborne dissemination @rki.de #Acinetobacter #infection #MicrobialEcology

MAU2 variants define a distinct CdLS subtype 🧬 In 18 individuals, 15 heterozygous variants disrupt MAU2–NIPBL function, show MAU2‑specific episignatures, and are validated in a Mau2 knockout mouse model 🐁 Read more:

New study shows that #deforestation in the #Amazon Basin has contributed substantially to the observed weakening of the #Atlantic Niño variability since 1970. www.nature.com/articles/s41...

Clinical trial: dolutegravir restores gut microbiota in late-stage HIV-1 patients better than darunavir, linked to improved immune reconstitution @rutgerwalls.bsky.social @fcatalamoll.bsky.social @irsicaixa.es @hospitalclinic.bsky.social

Ecology and evolution of the nosocomial pathogen Acinetobacter baumannii outside hospital settings: - soil-dwelling colonization of decaying plant material - airborne dissemination @rki.de #Acinetobacter #infection #MicrobialEcology

New study shows that explosive tropical #volcanic #eruptions can trigger pan-Asian #monsoon #droughts by initiating a circumglobal teleconnection, providing evidence of how volcanic forcing can affect #hydroclimate across #Asia. www.nature.com/articles/s41...

FOXA1 loss in mice shown to drive basal-squamous de-differentiation and to remodel the tumor microenvironment in prostate cancer doi.org/10.1038/s414...

Clinical trial: dolutegravir restores gut microbiota in late-stage HIV-1 patients better than darunavir, linked to improved immune reconstitution @rutgerwalls.bsky.social @fcatalamoll.bsky.social @irsicaixa.es @hospitalclinic.bsky.social

New perspective piece by Lei Wang (@leiwqg.bsky.social) and colleagues discusses current knowledge gaps and challenges in #atmospheric #blocking and extreme #weather research, offering recommendations on potential ways forward. @usclivar.bsky.social www.nature.com/articles/s41...

Ecological partitioning enables phage–antibiotic cooperation in a human Pseudomonas infection #Antibiotics & #PhageTherapy coordinate through ecological & immunologic complementarity rather than direct pharmacologic synergy @scientiff.bsky.social

New study presents “RePPIC-Net”, a hybrid #AI model that fuses #satellite data with AI #weather forecasts to decipher #snow from #rain with rapid speed and accuracy, paving the way for improved global #hazard alerts. www.nature.com/articles/s41...

Researchers Uncover Hidden Genetic World in Antarctic Waters "at least a third of the genes identified are missing from existing marine gene catalogs" @loimai.bsky.social #microbiome #oceans

Our paper is now out in its final form in @natcomms.nature.com ! We show that ancient insect symbionts can undergo extreme, convergent genome reduction to as little as ~50 kb - driven by ecological shifts and symbiont replacement. 🔗 www.nature.com/articles/s41... More below 👇 1/

Announcing Nature Progress Oncology! An open-access journal in the new Nature Progress series, publishing significant advances in cancer research, from cell biology and immunology, therapeutics, clinical research, and epidemiology nature.com/natprogoncology

Silencing bacteria can worsen heart infections In infectious disease research, disrupting bacterial communication is widely considered beneficial. A study by UNIGE & NTU Singapore shows this is not always true

#Virology Prenatal exposure to #Zika virus disrupts social-emotional development and cortical visual function in infant macaques @mohrlab.bsky.social

#Microbiology Loss of Fsr quorum sensing *promotes* biofilm formation and worsens outcomes in enterococcal infective endocarditis @kimingeneva.bsky.social @harisantypas.bsky.social @scelse.bsky.social#Microbiology #biofilms #bacteria

Announcing Nature Progress Brain Health! A new open-access journal bringing together timely research across the full landscape of brain health, including preclinical and translational neuroscience, neurology, and neuropsychiatry nature.com/natprogbrainhealth

New study shows that #ENSO phase transition enhances the #predictability of the winter North Atlantic Oscillation ( #NAO) one year ahead through atmospheric angular momentum dynamics, improving long-range #climate forecasts. www.nature.com/articles/s41...

New study sheds light on the drivers of summer #cooling ( #WarmingHole) over #India under greenhouse gas warming. Via an #atmospheric pathway, enhanced Eurasian warming increases #cloud cover and reduces solar radiation, leading to this regional cooling. www.nature.com/articles/s41...

Associations of #sleep characteristics with lifestyle factors and gut #microbiome composition in a cohort of over 6,900 participants

New study shows that #SoilMoisture – #atmosphere feedback (SAF) amplifies dry #heatwaves but reduces the duration and severity of humid ones in low-to-mid latitudes. This contrast arises from the competition between SAF-induced #warming and #moisture depletion. www.nature.com/articles/s41...

New study reports a record-breaking variation in the Eurasian #JetStream axis since 1999, which is enhanced with #GlobalWarming, and induces a circumglobal Silk Road teleconnection, linking #climate extremes across the Northern Hemisphere. www.nature.com/articles/s41...

SCELSE-NTU and UNIGE scientists find that silencing bacteria can worsen heart infections This video explains how disrupted quorum sensing drives aggressive biofilms in infective endocarditis — and what this means for future therapies @scelse.bsky.social

Condensin accelerates long‑range intra‑chromosomal interactions in budding yeast. Using CICI to measure encounter times across loci, the study provides a dynamic view of chromatin motion beyond static 3C snapshots. #NatureCommunications #Chromatin #YeastResearch

Associations of #sleep characteristics with lifestyle factors and gut #microbiome composition in a cohort of over 6,900 participants

#Virology Prenatal exposure to #Zika virus disrupts social-emotional development and cortical visual function in infant macaques @mohrlab.bsky.social

#Microbiology Loss of Fsr quorum sensing *promotes* biofilm formation and worsens outcomes in enterococcal infective endocarditis @kimingeneva.bsky.social @harisantypas.bsky.social @scelse.bsky.social#Microbiology #biofilms #bacteria

Silencing bacteria can worsen heart infections In infectious disease research, disrupting bacterial communication is widely considered beneficial. A study by UNIGE & NTU Singapore shows this is not always true

Scientists studied monkeys exposed to Zika before birth. They found that even when the mother’s infection looked mild, the babies showed some behavior and development differences such as vision and hearing impairment during the infant’s first year of life. www.nature.com/articles/s41...

What if quorum sensing doesn’t promote biofilms - but restrains it? 🤔 New work from @harisantypas.bsky.social shows that the Fsr QS system in Enterococcus faecalis acts as a brake on biofilm formation and pathogenesis during infective endocarditis (IE). www.nature.com/articles/s41...

Long‑read, phased genomes from 189 individuals reveal autism‑associated pathogenic variants, including complex SVs missed by short reads. Highlights variants in TBL1XR1, MECP2 & SYNGAP1. @uwgenome.bsky.social @humanpangenome.bsky.social #LongReadSequencing #StructuralVariants #AutismResearch

Cool new study in Nat Comm by Amanda Dugan, Deepsing Syangtan, et al that identifies INTELECTIN-2 as a broad-spectrum antimicrobial operating right at mucosal surfaces INTELECTIN-2 not only senses microbes, it actively shapes which microbes gets to stay 🧵 (1/5) @natcomms.nature.com

Beyond Viral Suppression: How the Right #HIV Drug Helps the Gut Heal Itself @rutgerwalls.bsky.social @fcatalamoll.bsky.social @irsicaixa.es @hospitalclinic.bsky.social#HIV#Microbiome

Beyond Viral Suppression: How the Right #HIV Drug Helps the Gut Heal Itself @rutgerwalls.bsky.social @fcatalamoll.bsky.social @irsicaixa.es @hospitalclinic.bsky.social#HIV#Microbiome

New study based on #cloud observations from 44 US cities and large-eddy simulations shows that taller buildings strengthen #urban - #breeze updrafts, while denser buildings suppress vertical #turbulence, reshaping #moisture transport and cloud formation. www.nature.com/articles/s41...

Beyond Viral Suppression: How the Right #HIV Drug Helps the Gut Heal Itself @rutgerwalls.bsky.social @fcatalamoll.bsky.social @irsicaixa.es @hospitalclinic.bsky.social#HIV#Microbiome

#Contrail avoidance can provide meaningful reductions in global #temperature rise. Delaying its adoption poses a larger #climate risk than the expected increase in fuel consumption. Read the authors’ blog post behind the paper. communities.springernature.com/posts/the-cl...

Intermediate #PRRX1 levels primes #cancer cell for high invasion and metastatic fitness, whereas extreme expression leads to cell cycle inhibition and #dormancy doi.org/10.1038/s414... @ruljcz.bsky.social @nietoangela.bsky.social

#LRRK2 inhibitors found to enhance viral infection and oncolysis by oncolytic herpes simplex virus #therapy in #glioblastoma doi.org/10.1038/s414...

eIF6 identified as a regulator of #SCLC small cell lung carcinoma #plasticity, driving non-neuroendocrine transdifferentiation via regulation of the CD104/FAK complex doi.org/10.1038/s414...

Discovery that #obesity induces the expression of the peptide hormone cholecystokinin (CCK) in #β-cells, affecting the peri-islet acinar cells and promoting islet-proximal #tumor formation @muzumdarlab.bsky.social @krishnaswamylab.bsky.social doi.org/10.1038/s414...

RIPK1-driven #necroptosis in both tumor and stromal compartments found to be essential for effective immunogenic cell death-based therapy and immune checkpoint @meierlabicr.bsky.social doi.org/10.1038/s414...