What will be the most pressing health challenge of 2026? A new Editorial discusses how conflict and armed violence are major determinants of global health, with far-reaching consequences that extend beyond battlefields: spkl.io/63326AlsFQ

More than 1 billion women and children were exposed to violence worldwide in 2023. On our first cover of 2026, a Comment highlights the urgent need for preventive measures to address this crucial public health priority and save lives. Read this & more: spkl.io/63322Alsfi

🗨️ “Vaccines have done more to improve public health than any other medical intervention.” A Viewpoint focuses on cancer vaccines and the future of immunotherapy: spkl.io/63322AYP7k

👀 Among our most-read in 2025: A study investigating the effectiveness of a preventive care strategy to reduce moderate or severe acute kidney injury after major surgery: spkl.io/63321AYEN1

What does it take to build a health system that works for everyone? On January 21, join us for the launch of the Lancet Commission on a Citizen-Centred Health System for India. Register now 👉 spkl.io/63325AlHSF

🏆 Its been the biggest honour of my life to win The Lancet 2025 Wakley Prize and have my essay published in the final @thelancet.com of the year 📖 🤩 It was the perfect #Christmas present to receive the paper edition, as a surprise delivery yesterday 🚚 📦 @wolfsonpallcare.bsky.social

Among our most-read in 2025 ⤵️ The US Agency for International Development (#USAID) funding has had a crucial role in improving global health. A study estimates that USAID programs have saved nearly 92 million lives over past 20 years: spkl.io/63324AYE2C

Oncolytic viruses have the unique ability to selectively replicate within (and to destroy) cancer cells, offering a promising approach in cancer treatment. A Review summarises clinical progress, remaining challenges, & future research directions: spkl.io/63321AYPN5

"...the climate is not merely a backdrop to human life, it is embedded in who we are and how we live." A Comment discusses the complex relationship between climate change, human migration, and health: spkl.io/63328AYPIa

👀 Among our most-read in 2025: A major meta-analysis investigating the effects of antidepressants on cardiometabolic and other physiological parameters. Find out more: spkl.io/63325AYEFX

New Hypothesis—Amylin and the renin-angiotensin system: risk or opportunity in amylin-based therapy? spkl.io/63329AYEvx

Among our most-read in 2025 ⤵️ Ultra-processed foods – what’s the impact? In a Lancet Series, experts warn a global rise in #UPFs presents a growing public health threat. Read the evidence & policy recommendations ⬇️ spkl.io/63323AYDz7

The therapeutic landscape for prostate cancer has evolved substantially in the past 5 years, resulting in improved patient outcomes. A new Seminar provides an up-to-date overview of the management of prostate cancer at different stages of the disease: spkl.io/63322AcVaC

In the 2025 Lancet #WakleyPrize winning essay, @donnawakefield.bsky.social explores how personal experiences and understanding of the social determinants of health can transform patient care and foster a more inclusive healthcare system. Read now 👉 spkl.io/63329AcBBV

"the most disastrous year for US public health policy" The US faces a critical public health crossroads as recent policy shifts threaten decades of progress. What are the implications for future health security and scientific integrity? Our Editorial: spkl.io/63326AcVQy

A picture is worth a thousand words 📷 In our final issue of 2025, explore the winning photos of The Lancet's 2025 Highlights competition, representing a year of pursuing health and hope in challenging conditions. Access the full issue: spkl.io/63327Aci33

Randomised controlled trials have commonly excluded women who are pregnant, lactating, or of reproductive potential. A new Viewpoint discusses the factors contributing to the exclusion of these women and provides recommendations to increase their inclusion: spkl.io/63328AiCtk

The Russian military's invasion of Ukraine has revived the threat of large-scale conflict in Europe. A new letter discusses the UK's need to prepare its healthcare system for potential large-scale military conflicts, providing key research priorities: spkl.io/63328AiAj4

Use of nicotine pouches has increased from 0.1% to 1% in the UK from 2020 to 2025, primarily driven by their use in young people, study suggests in @thelancetph.bsky.social Explore the research ➡️ spkl.io/63320AiU6g

Acute kidney injury (AKI) is a common and important complication of major surgery, yet recommended preventive care is rarely administered. A new study investigated the effectiveness of a preventive care strategy to reduce moderate or severe AKI after major surgery: spkl.io/63321Ai4Fl

Ageing is associated with cognitive decline & an increased risk of neurodegenerative diseases. A Review explores the neuroprotective mechanisms of endurance exercise & highlights the importance of cardiorespiratory fitness in healthy brain ageing: spkl.io/63323Aia89

Transcatheter aortic valve implantation with the Trilogy valve for symptomatic native aortic regurgitation (ALIGN-AR): a pivotal, multicentre, single-arm, investigational device exemption study spkl.io/63329AiS4U

The December 2025 issue of The Lancet Regional Health - Americas is now available online: lnkd.in/gf4aXrfm In this issue, we covered #NeglectedTropicalDiseases, #Type5Diabetes, #Mortality, #Dementia, #ChagasCardiomyopathy, #Mpox, #RSV, #Psychosis, #RespiratoryProtection, and much more.

NEW ISSUE: Our January 2026 issue is now live and includes the annual Round-up of key advances in research in neurological disorders in 2025. Read more at: thelancet.com/journals/lan...

"It is a huge responsibility. You stand up, knowing that everything you say is being recorded and the judge is watching you." In a new World Report, Talha Burki examines the place of medicine in the courtroom, including the role of expert witnesses: spkl.io/63320Aizvy

New single dose oral treatment for gonorrhoea effectively combats drug-resistant infections, trial finds. Find out more 👉 spkl.io/63326AizOe

One in four women experience heavy menstrual bleeding (HMB). A new study in @lancetobgyn-wh.bsky.social finds that HMB costs the NHS over £13 million each year, highlighting the urgent need to improve outpatient services and reduce the burden on hospitals: spkl.io/63321Aiz3l

“It's the cuts, ultimately, that are forcing us into these tough, brutal choices...” The UN and the ICRC have announced major reductions for their 2026 appeals, concentrating on only the most pressing crises. ✍️ John Zarocostas reports: spkl.io/63322AizKE

4·6 billion people lacked essential health services in 2023. Universal health coverage stands as the organising vision for national health systems. Yet translating this promise into reality has proven complex. On #UHCDay, read our latest Editorial: spkl.io/63328Aiz6e

On the cover this week, the 2025 @lancetcountdown.bsky.social report on health and climate change. Read this & more in our latest issue: spkl.io/63328AiKc2 #LancetClimate25

Heterozygous familial hypercholesterolemia is a common genetic condition characterised by high LDL cholesterol levels from a young age. A Review in @thelancetendo.bsky.social discusses the latest knowledge familial hypercholesterolaemia & its unmet clinical needs: spkl.io/63320AiBFu

The Democratic Republic of the Congo is facing its 16th Ebola outbreak. In The Lancet Regional Health - Africa, Patrick D.M.C. Katoto & colleagues outline five priority actions for the response: spkl.io/63329A9U7B

As fertility rates decline globally, the Asia-Pacific region faces some of the lowest birth rates worldwide. A new Series in The Lancet Regional Health – Western Pacific explores the contributing factors and proposes strategies to improve fertility outcomes: spkl.io/63321A95xS

How does research drive real change? Our new Lancet–Elsevier Foundation Evidence to Impact Award is open for proposals! If your project champions implementation science, health equity and community engagement, apply now: spkl.io/63320A9zNI

In high-risk pregnancies, there is no reliable intervention to reduce term pre-eclampsia. A new study investigated the effect of screening for pre-eclampsia risk at 36 weeks' gestation and offering risk-stratified, planned, early-term birth: spkl.io/63324A9z06

Government cash transfer programmes can significantly improve health outcomes for women and children in low- and middle-income countries, study finds. Explore the research ▶️ spkl.io/63324AgSyy

🆕 The first published Comments in The Lancet Regional Health - Africa are now available online! Topics include cholera, global health architecture, Ebola, & artificial intelligence. Read the Comments & find out more about the new journal: spkl.io/63329AgQkW

Eloralintide, a selective amylin receptor agonist for the treatment of obesity: a 48-week phase 2, multicentre, double-blind, randomised, placebo-controlled trial spkl.io/63325AgSD7

The rise of ultra-processed foods is damaging public health, fuelling chronic diseases worldwide, and deepening health inequalities. Urgent, coordinated global action is needed to address the UPF challenge. Find out more in an Editorial ➡️ spkl.io/63327AgUC1

Ultra-processed foods – what’s the impact? In a new Lancet Series, experts warn a global rise in #UPFs presents a growing public health threat. Read this & more in our new issue: spkl.io/63326AgUlK

Review—"Health care in the USA: money has become the mission" 👇 spkl.io/63325Agg1T

📢 Don't miss out! The Lancet Webinar on "Global strategies to reverse the rise of liver cancer" is now available to watch on-demand. Hear what our panel had to say about this pressing global health issue. ▶️ Watch now: hubs.li/Q03GK-qd0 #oncology #hepatology #lgcw2025

✏️This month's Editorial: Making prostate cancer screening fit for purpose www.thelancet.com/journals/lan...

🆕 Acute rheumatic fever (ARF) is an autoimmune disorder, involving the joints, heart, brain, skin, subcutaneous tissues, or a combination. A Seminar presents key updates on ARF, highlighting future research priorities: spkl.io/63325AgrIc

📢 Out today! A new Series, jointly with The Lancet HIV, on sustainable #HIV prevention in Africa www.thelancet.com/series-do/su...

"Not only is there demand for understanding health systems performance but there is also an opportunity to rethink and re-evaluate the assessment itself." A new Comment introduces the Lancet Commission on Health Systems Performance Assessment: spkl.io/63322A5C6g

Artificial intelligence is changing how we define impact and integrity in science. At 9am CET on 5th Dec, join a webinar exploring how we might harness AI responsibly while protecting the transparency that science relies on. Register now ➡️ tinyurl.com/k8mw4kk5

New issue is live!🙌 Read about smoking & #vaping in #Oceania, pediatric #MASLD in #China, smartphone-based #CBT in #Japan, #Malaria microscopy in #Indonesia & more! 🖋️ Editorial: #Diabetes underdiagnosis 🎨 Cover by Van-Mai CAO-LORMEAU 🔗 tinyurl.com/4haau2s3 #MedSky #IDSky #PsySky

ICYMI: a Series of papers in our December issue highlights advances in basic and clinical research that have the potential to transform management of Lewy body dementia: www.thelancet.com/series-do/de...

Getting smart about the food we eat www.thelancet.com/journals/lan... #ultraprocessed foods #UPFs #obesity #FREE to read with registration (also FREE) #MedSky #EndoSky