Elon Musk’s cuts to U.S.A.I.D. led to some 700,000 deaths, Atul Gawande says. www.newyorker.com/news/the-new...

Looking forward to presenting our latest findings on dual receptor T cells!

Great to share our recent review, written with @niclag.bsky.social and @danielthiele1.bsky.social @monashuniversity.bsky.social #monashBDI The evolving biology of T cell memory: A dynamic continuum of function and persistence | Science Immunology www.science.org/eprint/95PIC...

Thrilled to share our newest study led by @categraca.bsky.social and @yannick-alexandre.bsky.social published in @cp-immunity.bsky.social Here, we identify B cells as critical helpers for T cells to obtain effector function through enhancing IFN-I 😳 url.au.m.mimecastprotect.com/s/NE67C6X1Py...

We are looking for a PhD student to join our lab in Erlangen (www.schoberlab.de). Excited about human immunology, T cells, viruses, high-throughput screens, and mechanistic questions? Apply here: www.karriere.uk-erlangen.de/en/job/phd-s... Please share with candidates.

“It’s just a microscopic water droplet surrounded by a fatty membrane and stuffed with chemicals and snippets of DNA encoding a mere 36 genes. But it’s also arguably the closest researchers have come to building a living cell from scratch.”🧪 My story in @science.org on a fascinating preprint:

What are our blind spots in human T cell immunology? In "Current Opinion in Immunology", M. Hiltensperger and I argue that we lack a coherent understanding of epitope-specific responses in secondary lymphoid organs. www.sciencedirect.com/science/arti... Grazie, Marco & Matteo, for the invite!

An interesting finding: for medical questions, specialized large language models might perform worse than general-purpose LLMs such as chatGPT: www.nature.com/articles/s41...

The T Cell Receptor: Molecular Sensor, Therapeutic Mediator and Probabilistic Driver of Adaptive Immunity @kischober.bsky.social onlinelibrary.wiley.com/doi/10.1111/...

"The T Cell Receptor: Molecular Sensor, Therapeutic Mediator and Probabilistic Driver of Adaptive Immunity." My personal perspective on TCR (repertoires). Immunological Reviews: onlinelibrary.wiley.com/doi/epdf/10.... This is part of a special issue with contributions from great TCR colleagues.

"Integrating complementary approaches reveals antigen-reactive CD4+ T cell states after SARS-CoV-2 vaccination" New paper from our lab, just out in @cp-iscience.bsky.social. It is, for the time being, our last work on SARS-CoV-2 T cell responses. www.cell.com/iscience/ful...

Ein Team von Studierenden der FAU hat bei der diesjährigen Asian Supercomputer Challenge einen herausragenden Erfolg erzielt. Das Team „FAUltier“ überzeugte beim Finale des weltweit größten studentischen Supercomputerwettbewerbs als bestes internationales Team. www.fau.de/2026/06/news...

TL;DR: We've identified more than 100 cases of apparent manipulation in Thermo Fisher Scientific's antibody verification data. @sholtodavid.bsky.social @johanduchene.bsky.social reeserichardson.blog/2026/05/28/h...

@biorxivpreprint.bsky.social A scRNA-seq atlas of chronic inflammatory skin diseases www.biorxiv.org/content/10.6... isd-atlas.derma.meduniwien.ac.at

As global health budgets tighten, how should countries and policymakers decide which vaccines should be prioritised? While the answer varies depending on geography, context and myriad other factors, researchers have compare 14 vaccines on one crucial metric. Dig into the results: bit.ly/3P6qrXC

What is the spectrum of suspected pediatric meningoencephalitis in the era of conjugate vaccines and multiplex PCR diagnostics? 🧵 Our study is now published open access in Infection link.springer.com/article/10.1... 1/4

Should all children be vaccinated against influenza? Most pediatric infectious disease specialists would probably say yes — but universal influenza vaccination for children is still not generally recommended in Germany and many other European countries.

A new Lancet study just reported the primary mortality analysis from the RTS,S malaria vaccine implementation programme in Ghana, Kenya, and Malawi. The verdict after 46 months is 1 in 8 deaths averted in eligible children, a very important outcome. www.thelancet.com/journals/lan...

Deep peptide recognition profiling decodes TCR specificity and enables disease-associated antigen discovery - @stanfordmedicine.bsky.social go.nature.com/3QWMRet

Join us in Copenhagen, Denmark, for #HCVFlavi2026! The international conference on Hepatitis C Virus, Flaviviruses and Related viruses. 🗓️ Dates: September 14–17, 2026 ⏳Abstracts: May 12, 2026; Early Registration: June 14, 2026 hcv-flavi2026.org #Antivirals #HCV #Flavivirus #Vaccines

Exciting new work from Aaron Bodanksy and Joe DeRisi and colleagues on finding antigen-specific B cells and T cells in ROHHAD, a rare pediatric neuroendocrine disorder www.biorxiv.org/content/10.6...

I've spent yesterday and today talking to researchers across the globe trying to understand the hantavirus outbreak aboard the cruise ship MV Hondius. My story in @science.org is here (and some threaded thoughts coming): www.science.org/content/arti... 🧪 #IDsky

🟡 New from @kischober.bsky.social in Nature Immunology! Long-lived T cell memory after yellow fever vaccination depends on an early metabolic "standby mode" — confirmed also after COVID-19 vaccination. The most durable immune cells aren't the most active. Less sprinter, more marathon runner.

A compelling shift toward tissue-centric immunity: lymphoid niches don’t just initiate responses—they time and constrain them. Brilliant now work from Lukas Altenberger shows that timing of initiating and terminating immune response are equally important. www.science.org/doi/10.1126/...

Genome pioneer Craig Venter dies: he transformed science by redrawing the boundaries of biology — sequencing DNA at unprecedented speed, engineering synthetic life and charting ocean microbes www.nature.com/articles/d41...

A single dose of an AAV vector encoding the CCR5-blocking antibody leronlimab drives suppression of viremia in SHIV-infected macaques www.science.org/doi/10.1126/... @ohsunews.bsky.social

Clear Sky Science has written a very good summary of our work on the metabolic features of T cell subsets responding to yellow fever vaccination: www.clearskyscience.com/en/10.1038/s...

Try this: www.science.org/eprint/PGXMI...

together with Diyaa Ashour (@diyaa-ashour.bsky.social) and Leon Richter, we have compiled and curated a database of TCRs found expanded across various CVDs. You can access our browsable CVD-TCR database here: github.com/RamosImmunoC... For details: doi.org/10.1111/imr....

My lab has been studying human genes that control infection HIV infection of CD4+ T cells for over a decade. Today we report a major milestone in Cell: www.cell.com/cell/fulltex...

Today, in #preprinthub2 Chloe and Meredith @uvaimmunology.bsky.social will present a #preprint from the Martin Vaeth lab @uni-wuerzburg.de on how the glucose transporter GLUT3 controls #Treg function 🍬🚡🕹️ #immunosky www.biorxiv.org/content/10.6...

Die neue #AkademieAktuell ist da! Diesmal im Fokus: Barocke Deckenmalerei trifft auf KI & Virtual Reality – wie digitale Technologien 400 Jahre alte Kunst neu erlebbar machen. Jetzt das E-Paper lesen: tiny.badw.de/zYRRBq #Barock #DigitalHumanities #Kulturerbe @lmu.de @matteoburioni.bsky.social

Mich hat es sehr gefreut, dass in "Akademie Aktuell", der Zeitschrift der Bayerische Akademie der Wissenschaften über unsere Forschungsarbeiten zu T-Zell-Antworten nach SARS-CoV-2 Impfung berichtet wird. Direkter Link zum PDF unseres Artikels: badw.de/fileadmin/pu... @fau.de, @badw.de

Landmark ancient-genome study shows surprise acceleration of human evolution www.nature.com/articles/d41...

Happy to be nominated for the 2026 FAU Award for Doctoral Supervision. blogs.fau.de/proko/fau-aw... Good mentoring is any supervisor's job and moral obligation. But good mentoring will also make your research better, egoistically speaking. So there's really no reason not to put emphasis on this.

Why I study immune responses to vaccination: "Pediatric vaccines have saved the lives of 154 million children since 1974. Independently, COVID-19 (COVID) vaccines saved an estimated 20 million lives in 2021 alone. The efficacy of almost all human vaccines is dependent on immunological memory."

A patient with three rare autoimmune diseases in Germany has been symptom-free for over a year after a single dose of CAR T cell therapy. Avery Posey, PhD addresses risks + new developments for adapting the #immunotherapy as a treatment for autoimmune diseases in The Atlantic: https://bit.ly/4dG3nIY

We are recruiting 1-2 postdoctoral fellows to investigate the specificity of human anti-influenza virus antibodies, and to determine how these antibodies impact global antigenic drift of influenza viruses. Join our lab at Penn in Philly. Reach out if you are interested in applying! Please repost!

We’re unwrapping a new method today at @mskcancercenter.bsky.social. Led by Sydney Blattman, Nabih Maslah, and @austinv11.com with @danapeer.bsky.social, @ronanchaligne.bsky.social and @10xgenomics.bsky.social, we present GIFT: Genotyping In Fixed Transcriptomes www.biorxiv.org/content/10.6... 1/n

Balancing the efficacy and safety of chimeric antigen receptor T-cell therapy by affinity combination www.nature.com/articles/s41... @natcomms.nature.com

CD19 CAR-T therapy induces remission in refractory autoimmune hemolytic anemia with ITP and antiphospholipid syndrome @cp-med.bsky.social www.cell.com/med/abstract...

Do you think you would have discovered a gorilla hiding in plain sight in your data? We found that you are 3 times less likely to do so if you have a specific hypothesis in mind. *A hypothesis is a liability* (Night Science recap, Day 5) genomebiology.biomedcentral.com/articles/10....

Does anyone have serum/plasma from a cohort of (ambulatory) patients with herpes zoster (shingles) ? A small cohort would be fine. We will test if they have auto-Abs against type I IFNs, as the risk of zoster increases over 50 yo. Please RT or contact me !

"our findings delineate antigen-specific CD4+ T cell fates in different courses of human viral infections, identifying stem-like subsets as potential immunotherapeutic targets and highlighting the need for tailored strategies to re-direct or boost CD4+ T cell responses." #Immunology 🧪🩺

Monthly median Received to Accepted time (days) at Nature Genetics

Die Sesselfelsgrotte im Altmühltal ist ein ganz besonderer Ort. Seit 1964 wird sie von der FAU erforscht und brachte erstaunliche Funde hervor. Unter anderem entdeckten Forschende einen Neandertaler-Fötus dessen Alter auf 55.000 Jahre geschätzt wird. www.fau.de/2026/03/news...

Postdoc-Position in Computational Biology to develop multi-omics data integration with the goal to study complex co-morbidities for Parkinson's disease (PD) and inflammatory bowel disease (IBD) at the FAU Erlangen (Germany): www.karriere.uk-erlangen.de/job/postdoct...

This is wild! (please excuse pun) Large, randomized study showing that Wolbachia‑based Aedes mosquito population suppression alone can significantly reduce dengue infections in a real‑world, dense urban setting! #dengue #IDSky #singapore @nejm.org #MedSky

what sequencing-based strategy do people like to look at CRISPR/cas9 editing in a polyclonal cell population? in the past i have used Sanger+the TIDE algorithm. I know some labs amplify the target region and do NGS- if that option, what company would you use? any other options?