Spatial TCR profiling has the potential answers to key questions in cancer immunology, including revealing spatially coordinated T cell states in head and neck cancer @sciimmunology.bsky.social www.science.org/doi/10.1126/... www.science.org/doi/10.1126/... @bcmfromthelabs.bsky.social

New online! Anne-Katrin Pröbstel: B cells, antibodies and microbiota in autoimmune disease

The preprint on IMMREP25 TCR-epitope prediction challenge is now out on preprint, which reveals that unseen epitopes remains an unsolved problem in the field! doi.org/10.64898/202...

The Role of T Cells in Multiple Sclerosis: Molecular Mechanisms, Drivers, and Therapeutic Targets www.imrpress.com/journal/JIN/...

Why Is MS a More Frequent Complication of EBV Infection in Females? onlinelibrary.wiley.com/doi/10.1111/...

Preprint: B-cell depletion therapy in multiple sclerosis reduced EBV viral load and was coupled to a pronounced reduction in CD8+ T cell responses to all lytic EBV antigens www.researchsquare.com/article/rs-9...

Risk of Multiple Sclerosis Among Persons With Epstein-Barr Virus–Positive Mononucleosis A Population-Based Study www.neurology.org/doi/10.1212/...

🚨 Applications are now open for the 2027 Neuroimmune Communication in Health & Disease GRC & GRS!!! 📅 January 23–29, 2027 📍 Ventura Beach Marriott, Ventura, California, USA 💻 Apply by: October 18th, 2026 grc.org/neuroimmune-co…

DNA damage burden and inadequate repair in CUX2+ neurons contributes to selective vulnerability in neuroinflammatory injury @ucsfaging.bsky.social @universitypress.cambridge.org www.nature.com/articles/s41... www.nature.com/articles/s41...

Interplay between genetic and environmental risk factors in multiple sclerosis: what have we learned? academic.oup.com/brain/advanc...

Cytotoxic T cell recognition of α-synuclein drives pathogenic immune responses in multiple system atrophy. Cool paper on CD8 T cells and multiple system atrophy doi.org/10.1073/pnas...

Immune cell profiling reveals expanded stem cell–like memory T cells in anti-GAD65-associated neurological syndromes www.pnas.org/doi/10.1073/...

GZMH+ GZNK+ double positive CD8 T cells: EBV specific t cell expansion in cerebrospinal fluid of multiple sclerosis patients www.sciencedirect.com/science/arti...

Understanding if specific EBV variants are associated with MS is an important, unanswered question. Simple, but clever approach for beginning to answer this: academic.oup.com/narmolmed/ad...

Parse or 10x? any advice? we're thinking about trying Parse but would love some feedback from the #immunology community. this sequencing project is for lung #macrophages if that matters? please circulate and send me any info about your experiences!! @jeffmold.bsky.social have you used Parse?

Viral DNA load of 31 common viruses in human blood and saliva WGS shows marked variaton across age, time of day, season, and sex, with most viral abundnace male>female www.nature.com/articles/s41... @nature.com @broadinstitute.org @steve-mccarroll.bsky.social #Loh

Autoantibody landscapes in neurological Long COVID and post-COVID cognitive impairment show heterogeneity without a shared disease signature www.medrxiv.org/content/10.6...

In situ generation of EBNA1 CAR-T cells eradicates antigen specific auto-immune B cells for multiple sclerosis treatment www.sciencedirect.com/science/arti...

Next BIG ACTION is No Kings events - Saturday, March 28 SAVE SCIENCE. PROTECT HEALTH. DEFEND DEMOCRACY. Find your event at zurl.co/WSxhb Stand Up for Science will be hosting a Virtual Rally that day! Details coming soon. #NoKings3 #DefendDemocracy #SaveScience #ProtectHealth

2027 Neuroimmune Gordon Research Conference - Jan 24-29, 2027👇 www.grc.org/neuroimmune-...

Unique and interactive effects of race/ethnicity, genetics, herpesviruses, age, and gender on immunophenotypes @cp-cellrepmed.bsky.social @fredhutch.org @pgtimmune.bsky.social www.cell.com/cell-reports...

Overcoming T cell tolerance to tumor self-antigens through catch-bond engineering @science.org @stanforduniversity.bsky.social www.science.org/doi/10.1126/...

Review @natrevimmunol.nature.com Renaissance of antiviral CD8+ T cell immunity in vaccination and disease www.nature.com/articles/s41...

Preprint: Treatment of multiple sclerosis with CD19-targeting CAR-T-cells www.researchsquare.com/article/rs-9...

Happy to share the work of Aisha Shah about training predictors of TCR-epitope recognition with unpaired TCRa + TCRb sequences: www.biorxiv.org/content/10.6....

Unpaired TCRα + TCRβ sequencing is sufficient for training machine learning TCR-epitope recognition predictors https://www.biorxiv.org/content/10.64898/2026.03.16.711991v1

A gene-editing method generates immunotherapeutic CAR T cells in the body @nature.com @j-eyquem.bsky.social @ucsfhealth.bsky.social @ki.se www.nature.com/articles/d41... @heidiledford.bsky.social www.nature.com/articles/d41... www.nature.com/articles/s41...

Off-target reactivity in clinical monoclonal antibodies: Structure www.cell.com/structure/fu...

Exciting new work from Krista McKutcheon and Michael Wilson et al. identifying EBV cross-reactivity of an MS signature autoantibody www.neurology.org/doi/10.1212/...

Super stoked to share that I’m starting my lab at UHN @dkjei-uhn.bsky.social / @kbi-uhn.bsky.social and the University of Toronto! If you’re interested in neuron-myelin interactions in circuit maturation and cognition, please reach out - we are hiring! www.oligodendrocyte.org 1/

MS-BCR-DB: an integrated BCR repertoire database to mine humoral multiple sclerosis signatures www.biorxiv.org/content/10.6...

Not to be missed! Our next #globalimmuno talk, today Wednesday, March 11th, 2026 at 9am PST, noon EST, 4pm GMT by Dr. Justin Eyquem. Title: “Ex vivo and in vivo CRISPR editing to reprogram T cells” ZOOM LINK: us06web.zoom.us/webinar/regi... LIVE ON YOUTUBE: www.youtube.com/@GLOBALIMMUN...

Multiple molecular mimics in Epstein Barr Nuclear Antigen-1, and the pathogenesis of multiple sclerosis www.pnas.org/doi/full/10....

Thank you @sciam.bsky.social and @danvergano.bsky.social for covering the @standupforscience.bsky.social National Day of Action! www.scientificamerican.com/article/stan...

Epstein-Barr Virus Antibodies to Differentiate Multiple Sclerosis From Other Neuroinflammatory Diseases jamanetwork.com/journals/jam...

🚨Job alert - please share🚨 Senior Research Fellow (Programme Manager, Neuroimmunology), Trinity College Dublin (TCD), Ireland. my.corehr.com/pls/trrecrui... Are you an experienced researcher keen for a unique challenge? Want to help set up and lead a new neuroimmunology research team/lab in TCD...

Stand Up For Science National Day of Action San Francisco, California Saturday, March 7

For those in the SF Bay area, please consider attending the SUFS rally this Saturday, March 7 at SF City Hall from 1-3 pm #standupforscience @standupforscience.bsky.social fight2win.standupforscience.net/SF-March/

The Mettelman Lab at the University of Pittsburgh Center for Vaccine Research has officially opened its doors, and I’m looking to hire a Lab Manager! If interested, please apply using the link below Come join our team of 1! cfopitt.taleo.net/careersectio...

Epstein-Barr Virus Infection at Single-Cell Resolution onlinelibrary.wiley.com/doi/10.1002/...

STANFORD!!! Visit this link: fight2win.standupforscience.net/Stanford-Mar... to learn more about your local SATURDAY MARCH 7TH RALLY to TAKE BACK OUR SCIENCE! See map for location! Rally starts at 11am!! #March7Stanford #standupforscience #science #savescience

@biorxivpreprint.bsky.social Epigenomic profiling of cerebrospinal fluid cells identifies immune regulatory alterations and implicates protocadherins in multiple sclerosis www.biorxiv.org/content/10.6... @ki.se

FlowCLOc, a New Tool for Selecting the Most Appropriate Antibodies in Flow Cytometry www.mdpi.com/1422-0067/27...

Latent, Lytic, and Linked to Multiple Sclerosis—How EBV Drives Autoimmunity onlinelibrary.wiley.com/doi/10.1002/...

Excited to announce the 1st International Conference on T cells in Health and Disease, a new conference series aiming to bring together T cell biologists across diverse areas, from fundamental biology through to clinical translation, and spanning infection, autoimmunity and cancer.

Interested in understanding how epitope recognition specificity is encoded in your TCR sequences? Try our new interactive page for building TCR specificity profiles on the TCR Motif Atlas: tcrmotifatlas.unil.ch/Building_mot....

One more trick pulled off by antibody-mediated feedback www.cell.com/immunity/ful...

New work from our lab, hot off the press in Nature Immunology (@natureportfolio.nature.com)! How do human T cell responses diversify — and how does this lead to durable protection after vaccination? Paper: www.nature.com/articles/s41... Press release: www.fau.eu/2026/02/news... 1/6

Great work from @hollenbachlab.bsky.social and Michael Wilson's lab at UCSF!

Histidine scanning identifies TCR hotspots capable of forming additional catch bonds, facilitating screens for low-affinity, higher-potency variants lacking off- & on-target toxicity @cellcellpress.bsky.social #Xu #Zhao #Gascoigne www.cell.com/cell/fulltex...