Happy #treg day everyone - congratulations to Mary Brunkow, Fred Ramsdell, Shimon Sakaguchi and to all the immunologists who have contributed to this incredible field. See our collection: www.nature.com/collections/...

Happy to have our work highlighted on a day when we are celebrating #treg cells! These cells do it all, even modulate how we sense the environment!

Highlight of Science Immunology paper by @thepenkpanther.bsky.social, Alexander Rudensky and colleagues @mskcancercenter.bsky.social @scripps.edu @wcm-imp.bsky.social #immunology #immunosky #neurosky

NEW Review of neoadjuvant #immunotherapy in melanoma by Francesca Fallarino & Christian Blank @nkinl.bsky.social discusses where the field is heading next in terms of understanding immune education in therapy resistance and biomarker-driven personalization #immunology #oncology #cancer #melanoma

Just in time for #Cd1Mr12025 Our Review on Innate-like T cell Metabolism is out! Access free here: rdcu.be/eEV67 Please share with your Immunometabolism friends! @cd1mr1.bsky.social @lji.org @uniklinikkoeln.bsky.social @natureportfolio.nature.com @natrevimmunol.nature.com

NEW Review online now #immunosky

NEW Highlight of @natimmunol.nature.com paper www.nature.com/articles/s41...

📌In #September @natrevimmunol.nature.com issue, read our #comprehensive #Review: "The #Diversity of #CD8+ T #cell #dysfunction in #cancer and #viral #infection" ⏩Read: www.nature.com/articles/s41... 🤝Result of fruitful #Collaboration w/ @deadoc80.bsky.social @labliston.bsky.social & Kellie Smith!

#ThrowbackThursday: In 1980 the 🌍🌎🌏 was declared #smallpox free, thanks to mass vaccination efforts. Smallpox was an acute contagious disease caused by the variola virus. It was one of the most devastating diseases known to humanity. #VaccinesWork

The aryl hydrocarbon receptor has become a promising target for therapeutic immune modulation in inflammatory diseases, cancer and infections. Read about the field in this review in the August issue www.nature.com/articles/s41... rdcu.be/eBJKu

I must admit, I never quite knew how to imagine functional immune–brain crosstalk in situ. Thanks to our good friends at @aleksdelab.bsky.social, I can now read and see in @natrevimmunol.nature.com! doi.org/10.1038/s415... 🧪

It's great to see our review printed in @natrevimmunol.nature.com and learn that we made the cover! BRAIN on the cover of an IMMUNOLOGY journal 😍 review here: www.nature.com/articles/s41... Congratulations again! @marikovacs.bsky.social @amaia-db.bsky.social @fakesamir.bsky.social

And read our special Review from Chan, Martyn & Carter to mark 50 years of monoclonal antibodies: www.nature.com/articles/s41...

This discovery by Köhler and Milstein was revolutionary for biomedical research and drug development. Read the @nature.com editorial on the impact of monoclonal antibodies: www.nature.com/articles/d41...

Happy 50th birthday to monoclonal antibodies! While researching antibody diversity, Köhler and Milstein developed a technique for generating large amounts of monoclonal antibodies: www.nature.com/articles/256... #immunosky #immunology

NEW Review from @soreklab.bsky.social @dinahoch.bsky.social explains how immune pathways manipulate the availability of nucleotides, chemically modify nucleotides to generate immune signalling molecules, and produce altered nucleotides that poison viral replication #immunosky #microsky #phagesky

Congrats to Adam Grippin, a resident in the radiation oncology program @mdanderson.bsky.social , and soon to be physician scientist, on his latest commentary in @natrevimmunol.nature.com, highlighting a new cell surface mapping technique with implication in understanding immune cell functions.

Very happy to share this Perspective in @natrevimmunol.nature.com www.nature.com/articles/s41...

Another Journal Club article from @preprintclub.bsky.social - Mehdi Chaib and James Allison @mdanderson.bsky.social report on @biorxiv-immuno.bsky.social preprint by Han et al. that describes a mechanism by which metastatic tumours secure iron in the bone marrow #immunosky #cancersky rdcu.be/euBTD

NEW Journal Club article from @boyantsankovsci.bsky.social & Dana Philpott @preprintclub.bsky.social highlights a @biorxiv-immuno.bsky.social paper by Srivastava et al. that identifies a previously unknown C19S-modified insulin neoantigen. rdcu.be/et76Z

Highlight of a study by Teruyuki Sano and team in @nature.com revealing potential mechanisms by which commensal-specific T cells can contribute to extraintestinal inflammation #immunosky #microsky #neurosky

Thrilled to have co-authored this review with amazing colleagues! We dive into the mysteries of T cell immunity in TB and explore how cutting-edge tech could unlock better vaccines. #Tuberculosis #Immunology #TCells #Vaccines @natrevimmunol.nature.com www.nature.com/articles/s41...

It is truly an honor that my article has been chosen for the @natrevimmunol.nature.com journal club ! @aphp.bsky.social @hopitalrobertdebre.bsky.social

Review @natrevimmunol.nature.com @yaelalippe.bsky.social @msdiamondlab.bsky.social Innate immune responses to pathogens at the maternal–fetal interface www.nature.com/articles/s41...

Please consider applying for the Young Investigator Award @emds2025.bsky.social Full details at www.emds2025.com @britsocimm.bsky.social @edinuni-irr.bsky.social @uofgsii.bsky.social @natrevimmunol.nature.com

Thrilled to see our review out in @natrevimmunol.nature.com together with my amazing mentors @jfcryan.bsky.social and Ger Clarke. @apcmicrobiomeirel.bsky.social @anatneuroucc.bsky.social @uccresearch.bsky.social www.nature.com/articles/s41...

A Perspective article by @lilykeane.bsky.social, Gerard Clarke & @jfcryan.bsky.social @apcmicrobiomeirel.bsky.social proposes that microbiota–microglia cross-talk may have major implications for our understanding of neurological disorders and neuropsychiatric disease #immunosky #microsky #microbiome

Vaccines are rigorously tested, they are effective, and they save lives. More than 150 million lives have been saved in the past 50 years thanks to vaccines! But you may be worried about what's in them? So, let’s break it down ⬇

NEW Journal Club article from @preprintclub.bsky.social discusses @biorxiv-immuno.bsky.social preprint by Ellul et al. showing that maternal immune activation in mice drives regulatory T cell dysfunction in offspring and autism-like behaviours rdcu.be/eo65K

And another paper from @kedmiranit.bsky.social, published in @nature.com, after this Highlight was written, adds to the story www.nature.com/articles/s41...

Not one, not two .... but FIVE recent papers highlighting a role for RORgt+ antigen-presenting cells in the gut in establishing tolerance to food antigens #oraltolerance #immunosky #foodallergy

A way to improve a person's immune system response is through the diversity of their microbiome www.nature.com/articles/s41...

NEW Preprint Watch from Annette Wu & @wenjiang-nano.bsky.social @preprintclub.bsky.social reporting on @biorxiv-immuno.bsky.social preprint by @colinraposo.bsky.social et al. showing that checkpoint blockade drives expansion of exhausted T cell clones that develop functional memory rdcu.be/ek1kY

Last chance to submit late-breaking abstracts for IUIS 2025!

Highly recommend!

Our perspective in @natrevimmunol.nature.com on new concepts in neuroimmune interactions that have challenged the old dogma that immune privilege is a result of the isolation of the nervous and immune systems. @jonykipnis.bsky.social www.nature.com/articles/s41...

NEW Review online by Morgan Huse @mskcancercenter.bsky.social looks at how mechanical forces contribute to the potency, specificity and efficacy of the cytotoxic lymphocyte response #immunosky

Old & amazing way to shuffle the evolutionary cards, from bacteria & fungi to the immune system. #transposons: heavily used across labs, never tired of them. Discussed here through the lens of #immunology #evolution @natrevimmunol.nature.com

Celebrate International #DayofImmunology by treating yourself to one of our events or training courses! 🎉 Whether its our Diversity in Immunology event, next week’s Flow Cytometry training, or the BSI Immunology Awards - there's something for you 👀 bit.ly/3v2aAi1

In my first bsky post, I am excited to share our recent review out in @natrevimmunol.bsky.social. We discuss mechanisms that identify patterns of pathogenesis -- specific ligands or symptoms in the host that indicate active infection with an infectious microorganism. www.nature.com/articles/s41...

Thanks @natrevimmunol.bsky.social for highlighting our recent @nature.com paper! @flindersuniversity.bsky.social @sahmri.bsky.social

In person tix all gone, but you can still join us online today for our public outreach event on the immune system and your brain. Kicks off 18:00 BST. Link here: www.crick.ac.uk/whats-on/wor...

Our preprint by @raquelbuj.bsky.social was highlighted! What a cool idea to give early career scientists the opportunity to practice peer review skills! See the updated preprint: www.biorxiv.org/content/10.1....

Not one but two new Journal Club articles from @preprintclub.bsky.social discussing recent @biorxiv-immuno.bsky.social preprints on iron and zinc homeostasis in #macrophages. #immunosky

NEW Highlight of @nature.com paper by @davidjlynn.bsky.social and colleagues @sahmri.bsky.social reporting a prospective observational study of human immune responses to #vaccination after early-life #antibiotic exposure. #immunology #immunosky #medsky #IDsky #pedsky #publichealth

CD8+ T cell dysfunction extends beyond exhaustion. This @natrevimmunol review by @deadoc80, Kellie Smith, @labliston & @abhishekgarglab proposes a unified framework encompassing anergy, tolerance, exclusion, and senescence in cancer and infection. doi.org/10.1038/s415... 🧪

In this Review from our May issue, Shintaro Iwama, Tomoko Kobayashi & Hiroshi Arima discuss the management, biomarkers and prognosis in people developing #endocrinopathies associated with #immune checkpoint inhibitors (£) go.nature.com/43TbTQ2 #EndoSky

Our @natrevimmunol.bsky.social review with @abhishekgarglab.bsky.social, @deadoc80.bsky.social and Kellie Smith is out! We attempt to integrate the data on CD8 T cell dysfunction into a new framework of hypofunctionality in cancer and chronic infections! www.nature.com/articles/s41...

📢Happy to share our @natrevimmunol.bsky.social article; Result of #collaboration with @deadoc80.bsky.social @labliston.bsky.social & K Smith! 📑Read here: rdcu.be/ehm67 🔥Take🏠msg: Time to move away from narrow concept of #exhausted T cells to other #hypofunctional #states! 1/6🧵 @oncodaily.bsky.social

A reminder to register for our public outreach event in 2 weeks' time - it's free and you can join IRL (@crick.ac.uk London) or online. It's aimed at non-scientists, but we'll not throw you out if you already know a bit of T cell trivia... www.crick.ac.uk/whats-on/wor...