See the new consensus statement on 'Guidelines for T cell nomenclature': www.nature.com/articles/s41... Register to join our webcast on Monday 8th December www.workcast.com/register?cpa...

CAR T cells are a promising and effective cancer therapy but are difficult to regulate once implanted. This study in Nature Reviews Chemistry covers an emerging wave of small-molecule-based systems developed to control, augment and direct CAR T cell therapeutics. go.nature.com/47RdzK8 🔒

ICYMI🚨 In light of the #NobelPrize recognizing discoveries in peripheral immune tolerance, our article "Regulatory T cells in the tumour microenvironment" is now free to read. Discover how #Tregs shape cancer immunity 📖 👇

It has been a real pleasure to dive deep into the wonderful world of the unique and peculiar shape of the neutrophil nucleus, together with Ananda and Irina in the @udalovalab.bsky.social, and I'm proud this literature review is now out in @natrevimmunol.nature.com. rdcu.be/ePKFk

Three new #immunology #preprint Journal Clubs from @preprintclub.bsky.social now online: thanks to all our contributors!

We (@walmsley-lab.bsky.social) are thrilled to have our pre-print highlighted by the Journal Club from @natrevimmunol.nature.com We think single cell proteomics has the capacity to revolutionise our understanding of neutrophil functional heterogeneity, shown here in glioblastoma.

Highlight of @natimmunol.nature.com paper by @mas-g.bsky.social @walmsley-lab.bsky.social showing epigenetic reprogramming of neutrophils in response to hypoxia to reduce lung tissue damage #immunosky

#Medsky🧪 #immunosky @natrevimmunol.nature.com In this Review, the researchers examine recent data supporting the idea that the process of #phagocytosis is an integral mechanism of #innateimmune sensing & current efforts to comprehensively define the innate mechanisms at work inside #phagosomes

Great to see our review on the role of microglia, the 'gardeners' of the brain, in modulating the gut-brain axis make the cover of this months @natrevimmunol.nature.com

Thrilled to share our Perspective on structural immunity, where we discuss how immune cells double as architects, weaving and reshaping the fabric of our tissues. Grateful to @drusqui.bsky.social, all co-authors, and the wonderful @natrevimmunol.nature.com team for making it such a joy to write!

November issue now online www.nature.com/nri/volumes/... Cover art inspired by a Perspective article by @lilykeane.bsky.social, Gerard Clarke & @jfcryan.bsky.social on the role of microglia, the 'gardeners' of the brain, in modulating the gut-brain axis www.nature.com/articles/s41...

Thank you to our editor, Kirsty Minton, and the staff at NRI for the opportunity to share our thoughts on this emerging topic.

A Review article by Jeremy Baldwin, @cheuserloy.bsky.social & Luca Gattinoni discusses emerging strategies to modulate #organelle functions — including the transfer or transplantation of native or synthetic organelles — that could enhance #cancer #immunotherapy. #immunosky

NEW Perspective by @alazozcan.bsky.social, Tommaso Vicanolo, Veronique Angeli, Yuval Rinkevich & @drusqui.bsky.social presents a model of immune cells as architects of tissue barriers, by depositing matrix components or by interactions with structural cells and the ECM #structuralimmunity #immunosky

A new subspecialty takes off! Astroimmunology is focused on the effects of #spaceflight on the #immunesystem and defines avenues for countermeasures. A bonus: the work will also inform research on #aging @natrevimmunol.nature.com evimmunol.nature.com www.buckinstitute.org/news/a-hitch...

Organelle fitness ➡️ cell fitness Curious what we know about organelles in T cell function, how we learned and ways to boost therapies? Just out @natrevimmunol.nature.com: rdcu.be/eJ90x

Happy #treg day everyone - congratulations to Mary Brunkow, Fred Ramsdell, Shimon Sakaguchi and to all the immunologists who have contributed to this incredible field. See our collection: www.nature.com/collections/...

Happy to have our work highlighted on a day when we are celebrating #treg cells! These cells do it all, even modulate how we sense the environment!

Highlight of Science Immunology paper by @thepenkpanther.bsky.social, Alexander Rudensky and colleagues @mskcancercenter.bsky.social @scripps.edu @wcm-imp.bsky.social #immunology #immunosky #neurosky

NEW Review of neoadjuvant #immunotherapy in melanoma by Francesca Fallarino & Christian Blank @nkinl.bsky.social discusses where the field is heading next in terms of understanding immune education in therapy resistance and biomarker-driven personalization #immunology #oncology #cancer #melanoma

Just in time for #Cd1Mr12025 Our Review on Innate-like T cell Metabolism is out! Access free here: rdcu.be/eEV67 Please share with your Immunometabolism friends! @cd1mr1.bsky.social @lji.org @uniklinikkoeln.bsky.social @natureportfolio.nature.com @natrevimmunol.nature.com

NEW Review online now #immunosky

NEW Highlight of @natimmunol.nature.com paper www.nature.com/articles/s41...

📌In #September @natrevimmunol.nature.com issue, read our #comprehensive #Review: "The #Diversity of #CD8+ T #cell #dysfunction in #cancer and #viral #infection" ⏩Read: www.nature.com/articles/s41... 🤝Result of fruitful #Collaboration w/ @deadoc80.bsky.social @labliston.bsky.social & Kellie Smith!

#ThrowbackThursday: In 1980 the 🌍🌎🌏 was declared #smallpox free, thanks to mass vaccination efforts. Smallpox was an acute contagious disease caused by the variola virus. It was one of the most devastating diseases known to humanity. #VaccinesWork

The aryl hydrocarbon receptor has become a promising target for therapeutic immune modulation in inflammatory diseases, cancer and infections. Read about the field in this review in the August issue www.nature.com/articles/s41... rdcu.be/eBJKu

I must admit, I never quite knew how to imagine functional immune–brain crosstalk in situ. Thanks to our good friends at @aleksdelab.bsky.social, I can now read and see in @natrevimmunol.nature.com! doi.org/10.1038/s415... 🧪

It's great to see our review printed in @natrevimmunol.nature.com and learn that we made the cover! BRAIN on the cover of an IMMUNOLOGY journal 😍 review here: www.nature.com/articles/s41... Congratulations again! @marikovacs.bsky.social @amaia-db.bsky.social @fakesamir.bsky.social

And read our special Review from Chan, Martyn & Carter to mark 50 years of monoclonal antibodies: www.nature.com/articles/s41...

This discovery by Köhler and Milstein was revolutionary for biomedical research and drug development. Read the @nature.com editorial on the impact of monoclonal antibodies: www.nature.com/articles/d41...

Happy 50th birthday to monoclonal antibodies! While researching antibody diversity, Köhler and Milstein developed a technique for generating large amounts of monoclonal antibodies: www.nature.com/articles/256... #immunosky #immunology

NEW Review from @soreklab.bsky.social @dinahoch.bsky.social explains how immune pathways manipulate the availability of nucleotides, chemically modify nucleotides to generate immune signalling molecules, and produce altered nucleotides that poison viral replication #immunosky #microsky #phagesky

Congrats to Adam Grippin, a resident in the radiation oncology program @mdanderson.bsky.social , and soon to be physician scientist, on his latest commentary in @natrevimmunol.nature.com, highlighting a new cell surface mapping technique with implication in understanding immune cell functions.

Very happy to share this Perspective in @natrevimmunol.nature.com www.nature.com/articles/s41...

Another Journal Club article from @preprintclub.bsky.social - Mehdi Chaib and James Allison @mdanderson.bsky.social report on @biorxiv-immuno.bsky.social preprint by Han et al. that describes a mechanism by which metastatic tumours secure iron in the bone marrow #immunosky #cancersky rdcu.be/euBTD

NEW Journal Club article from @boyantsankovsci.bsky.social & Dana Philpott @preprintclub.bsky.social highlights a @biorxiv-immuno.bsky.social paper by Srivastava et al. that identifies a previously unknown C19S-modified insulin neoantigen. rdcu.be/et76Z

Highlight of a study by Teruyuki Sano and team in @nature.com revealing potential mechanisms by which commensal-specific T cells can contribute to extraintestinal inflammation #immunosky #microsky #neurosky

Thrilled to have co-authored this review with amazing colleagues! We dive into the mysteries of T cell immunity in TB and explore how cutting-edge tech could unlock better vaccines. #Tuberculosis #Immunology #TCells #Vaccines @natrevimmunol.nature.com www.nature.com/articles/s41...

It is truly an honor that my article has been chosen for the @natrevimmunol.nature.com journal club ! @aphp.bsky.social @hopitalrobertdebre.bsky.social

Review @natrevimmunol.nature.com @yaelalippe.bsky.social @msdiamondlab.bsky.social Innate immune responses to pathogens at the maternal–fetal interface www.nature.com/articles/s41...

Please consider applying for the Young Investigator Award @emds2025.bsky.social Full details at www.emds2025.com @britsocimm.bsky.social @edinuni-irr.bsky.social @uofgsii.bsky.social @natrevimmunol.nature.com

Thrilled to see our review out in @natrevimmunol.nature.com together with my amazing mentors @jfcryan.bsky.social and Ger Clarke. @apcmicrobiomeirel.bsky.social @anatneuroucc.bsky.social @uccresearch.bsky.social www.nature.com/articles/s41...

A Perspective article by @lilykeane.bsky.social, Gerard Clarke & @jfcryan.bsky.social @apcmicrobiomeirel.bsky.social proposes that microbiota–microglia cross-talk may have major implications for our understanding of neurological disorders and neuropsychiatric disease #immunosky #microsky #microbiome

Vaccines are rigorously tested, they are effective, and they save lives. More than 150 million lives have been saved in the past 50 years thanks to vaccines! But you may be worried about what's in them? So, let’s break it down ⬇

NEW Journal Club article from @preprintclub.bsky.social discusses @biorxiv-immuno.bsky.social preprint by Ellul et al. showing that maternal immune activation in mice drives regulatory T cell dysfunction in offspring and autism-like behaviours rdcu.be/eo65K

And another paper from @kedmiranit.bsky.social, published in @nature.com, after this Highlight was written, adds to the story www.nature.com/articles/s41...

Not one, not two .... but FIVE recent papers highlighting a role for RORgt+ antigen-presenting cells in the gut in establishing tolerance to food antigens #oraltolerance #immunosky #foodallergy

A way to improve a person's immune system response is through the diversity of their microbiome www.nature.com/articles/s41...

NEW Preprint Watch from Annette Wu & @wenjiang-nano.bsky.social @preprintclub.bsky.social reporting on @biorxiv-immuno.bsky.social preprint by @colinraposo.bsky.social et al. showing that checkpoint blockade drives expansion of exhausted T cell clones that develop functional memory rdcu.be/ek1kY

Last chance to submit late-breaking abstracts for IUIS 2025!