Wen Jiang MD, PhD
@wenjiang-nano.bsky.social
đ€ 436
đ„ 61
đ 18
Radiation oncologist and physician scientist
Our latest article is online
@natcancer.nature.com
describing the application of
#nanotechnology
in
#immuno-oncology
. A great effort led by Adam Grippin, our star Holman resident and soon to be Physician Scientist.
@bettykimmdphd.bsky.social
@mdanderson.bsky.social
@eileenparkes.bsky.social
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Nanotechnology for immuno-oncology - Nature Cancer
Kim and colleagues provide an overview of the current state of the art of nanomaterials and their application in immuno-oncology, discussing preclinical development and the clinical landscape.
https://www.nature.com/articles/s43018-025-01025-x
about 2 months ago
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reposted by
Wen Jiang MD, PhD
Rita Strack
2 months ago
My colleagues at Nature Biomedical Engineering
@natbiomedeng.nature.com
are hiring an associate or senior editor. Ideal applicant will have expertise in immunology, immunotherapy, or immuno-oncology. Please feel to ask me questions!
springernature.wd3.myworkdayjobs.com/SpringerNatu...
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Associate or Senior Editor, Nature Biomedical Engineering
Job Title: Associate or Senior Editor, Nature Biomedical Engineering Organization: Nature Portfolio Location: New York, Jersey City, Shanghai or Beijing â Hybrid Working Closing date: August 20, 2025 ...
https://springernature.wd3.myworkdayjobs.com/SpringerNatureCareers/job/New-York/Associate-or-Senior-Editor--Nature-Biomedical-Engineering_JR103891
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Congrats to Adam Grippin, a resident in the radiation oncology program
@mdanderson.bsky.social
, and soon to be physician scientist, on his latest commentary in
@natrevimmunol.nature.com
, highlighting a new cell surface mapping technique with implication in understanding immune cell functions.
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Mitochondrial proteins go public and novel interactions: insights from surfaceome mapping - Nature Reviews Immunology
A recent preprint by Floyd et al. presents the most comprehensive mapping to date of the human lymphocyte âsurfaceomeâ.
https://www.nature.com/articles/s41577-025-01216-8
2 months ago
0
6
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Congrats on a new commentary from Ben &
@bettykimmdphd.bsky.social
@natrevimmunol.nature.com
on a preprint detailing a pan-cancer antigen atlas for human cancers.
@mdanderson.bsky.social
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Uncovering the hidden landscape of tumour antigens - Nature Reviews Immunology
A preprint by Li et al. presents a comprehensive pan-cancer atlas of tumour-specific peptides that markedly expands the known tumour antigen repertoire.
https://www.nature.com/articles/s41577-025-01198-7
4 months ago
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Our latest publication led by Yifan Wang is now
@acs.org
on developing a generative
#AI
#LLM
to help design
#nanomedicine
.
@mdanderson.bsky.social
@bettykimmdphd.bsky.social
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A Generative Artificial Intelligence Copilot for Biomedical Nanoengineering
The recent success of large language models (LLMs) in performing natural language processing tasks has increased interest in applying generative artificial intelligence (AI) to scientific research. Ho...
https://pubs.acs.org/doi/10.1021/acsnano.5c03454
5 months ago
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0
0
reposted by
Wen Jiang MD, PhD
Aria Vaishnavi, PhD
5 months ago
I am thrilled to share that the first preprint from my lab is now available on bioRxiV! In this study, our team elucidates the role of autocrine ligands in the aberrant behavior of oncogene-driven lung cancer.
www.biorxiv.org/content/10.1...
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BRAFV600E-Driven Lung Tumorigenesis Requires Ligand-Mediated Activation of ERBB Receptor Signaling
Secretion of ligands of the human epidermal growth factor (EGFR) family of receptors or erythroblastic leukemia viral oncogene family (ERBB1-4) is a feature common to many cancer cells. However, our u...
https://www.biorxiv.org/content/10.1101/2025.05.04.652129v1
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reposted by
Wen Jiang MD, PhD
Nature Reviews Immunology
5 months ago
NEW Preprint Watch from Annette Wu &
@wenjiang-nano.bsky.social
@preprintclub.bsky.social
reporting on
@biorxiv-immuno.bsky.social
preprint by
@colinraposo.bsky.social
et al. showing that checkpoint blockade drives expansion of exhausted T cell clones that develop functional memory
rdcu.be/ek1kY
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Progenitor exhausted T cells contribute to the formation of immunological memory
Nature Reviews Immunology - A preprint by Raposo et al. shows that immune checkpoint blockade drives the expansion of certain clones of exhausted T cells that can develop into functional memory...
https://rdcu.be/ek1kY
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Sharing the latest commentary by our amazing PhD student Annette Wu
@natrevimmunol.nature.com
previewing exciting work from
@stanfordmedicine.bsky.social
on the formation of memory T cells in the setting of chronic stimulation.
@mdanderson.bsky.social
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Progenitor exhausted T cells contribute to the formation of immunological memory - Nature Reviews Immunology
A preprint by Raposo et al. shows that immune checkpoint blockade drives the expansion of certain clones of exhausted T cells that can develop into functional memory cells after clearance of chronic v...
https://www.nature.com/articles/s41577-025-01182-1
5 months ago
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Greatly enjoyed
@twanlammers.bsky.social
visiting Houston! Enjoying some classic Texan protein in preparation for his high caloric burning seminar.
6 months ago
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Our latest paper in collaboration with
@jacques-lux.bsky.social
describing using
#US
to activate
#sting
for
#cancerimmunotherapy
is now online in AdvScience.
@mdanderson.bsky.social
@utswtxid.bsky.social
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Targeted STING Activation Using Modified UltrasoundâResponsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microb...
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202416596
6 months ago
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Research briefing describing our latest paper is now online
@naturecancer.bsky.social
rdcu.be/ecf1I
@mdanderson.bsky.social
@ackoongmdphd.bsky.social
@bettykimmdphd.bsky.social
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An antibodyâtoxin conjugate enhances innate immune cell responses in tumors
Nature Cancer - Traditional antibodyâtoxin conjugates (ATCs) are designed to target and destroy cancer cells. We present an ATC that acts on innate immune cells to promote tumor-cell...
https://rdcu.be/ecf1I
7 months ago
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reposted by
Wen Jiang MD, PhD
MD Anderson Cancer Center
7 months ago
MD Anderson researchers have developed a novel antibody toxin-conjugate thatâs not designed to kill the cancer cells directly. Read how this new approach is designed to trigger the body's natural immune response instead:
bit.ly/4bhtToM
#EndCancer
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MD Anderson researchers develop novel antibody-toxin conjugate
Researchers at The University of Texas MD Anderson Cancer Center have developed a novel antibody-toxin conjugate (ATC) designed to stimulate immune-mediated eradication of tumors. According to preclin...
https://www.mdanderson.org/newsroom/md-anderson-researchers-develop-novel-antibody-toxin-conjugate.h00-159774078.html
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Our newest article is online
@naturecancer.bsky.social
A new antibody drug conjugate that doesnât kill tumor cells but rely on immune system to eradicate cancer.
@bettykimmdphd.bsky.social
@mdanderson.bsky.social
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An antibodyâtoxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy
Nature Cancer - Schrank et al. report the design and characterization of an antibodyâtoxin conjugate targeting CD47, promoting anti-tumor immunity in preclinical cancer models.
https://www.nature.com/articles/s43018-025-00919-0.epdf?sharing_token=hGWVT7thdKM3eyBEK4zlDtRgN0jAjWel9jnR3ZoTv0MMpoyT-zSm_Dsr2BhpcAPiDE-Yruh6fCl7_l_CvqunMQyJyddhaAr69c-_Gn_1nwu__Ro_eeCalcaQbaaBFXDAQNOsi56Wh5P9IrjHtuzRduhUIUQDKM3Na7FJP0lyxA0%3D
7 months ago
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reposted by
Wen Jiang MD, PhD
MD Anderson Cancer Center
7 months ago
MD Anderson is grateful to the Cancer Prevention and Research Institute of Texas for providing nearly $23 million to support our ongoing research and faculty recruitment. Read about the research it will benefit:
brnw.ch/21wQOF9
#EndCancer
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MD Anderson receives nearly $23 million in CPRIT funding for cancer research, faculty recruitment
The University of Texas MD Anderson Cancer Center today was awarded nearly $23 million from the Cancer Prevention and Research Institute of Texas (CPRIT) in support of 20 cancer research projects to a...
https://brnw.ch/21wQOF9
1
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Hanging out with old doctoral study advisor in Singapore. Talking about science over beautiful scenery and amazing food.
7 months ago
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reposted by
Wen Jiang MD, PhD
Nature Reviews Bioengineering
10 months ago
Understanding how nanoparticles interact with biological systems is crucial for the development and implementation of nanoparticles in clinical settings. This article explores multi-omics approaches to decipher the interactions of nanoparticles and biological systems:
https://go.nature.co...
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Multi-omics approaches to decipher the interactions of nanoparticles and biological systems - Nature Reviews Bioengineering
The interactions of nanoparticles with the body are dynamic and complex. This Perspective examines the application of different multi-omics tools to investigate nanoâbio interactions in vitro and in vivo.
https://go.nature.com/41Ev9Q8?utm_source=bluesky&utm_medium=social&utm_campaign=natrevbioeng
0
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reposted by
Wen Jiang MD, PhD
Albert Koong
9 months ago
Congrats to
@wenjiang-nano.bsky.social
! Well deserved recognition. @MDAndersonNews
#endcancer
#radonc
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Finishing up 2024 with our latest paper in Nature Rev Bioengineering on using multiomic tools to study bio-nano interactions.
@bettykimmdphd.bsky.social
@mdanderson.bsky.social
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Multi-omics approaches to decipher the interactions of nanoparticles and biological systems - Nature Reviews Bioengineering
The interactions of nanoparticles with the body are dynamic and complex. This Perspective examines the application of different multi-omics tools to investigate nanoâbio interactions in vitro and in v...
https://www.nature.com/articles/s44222-024-00264-4
10 months ago
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reposted by
Wen Jiang MD, PhD
Betty Kim
10 months ago
Grateful for this holiday season. Especially for our family, friends, mentors and our trainees who fills us with joy, love, laughter and kindness. Our first attempt at roasting a turkey finally became reality at 9pm.
#Thankful
#SomeonesSmoked&RaginCajunTurkiesWereBetter
@wenjiang-nano.bsky.social
0
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1
reposted by
Wen Jiang MD, PhD
Betty Kim
10 months ago
Great time tonight with guest Dolores Hambardzumyan and our colleagues Jason Schenkel,
@wenjiang-nano.bsky.social
and
#JPAI
members
@pamsharmamdphd.bsky.social
@jimallisonphd.bsky.social
Xi Chen
@mdanderson.bsky.social
#myeloid
#GBM
#endcancer
1
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reposted by
Wen Jiang MD, PhD
Padmanee (Pam) Sharma, MD, PhD
10 months ago
www.nature.com/articles/s41...
Sharing our latest review article to highlight the importance of appropriately developing combination strategies for immune checkpoint therapy. Grateful for working with 3 brilliant scientists: Sangeeta Goswami, Kristen Pauken & Linghua Wang
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Next-generation combination approaches for immune checkpoint therapy - Nature Immunology
In this Review, Sharma and colleagues describe the current landscape of combination therapies and discuss requirements for the development of effective combination strategies.
https://www.nature.com/articles/s41590-024-02015-4
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