Macrophage calcium signaling dynamics revealed using genetically-encoded sensors https://www.biorxiv.org/content/10.64898/2026.07.13.737685v1

SemVac: A Semantic Vaccinology Paradigm Powered by LLMs for Antigen Discovery https://www.biorxiv.org/content/10.64898/2026.07.13.737696v1

Inflammatory arthritis disrupts ocular immune privilege by compromising blood-retinal barrier integrity and promoting uveitogenic T cell recruitment https://www.biorxiv.org/content/10.64898/2026.07.13.738174v1

ITPKB is a conserved regulator of natural killer cell desensitization/education that constrains antitumor immunity https://www.biorxiv.org/content/10.64898/2026.07.12.738073v1

Integrating activation-induced costimulation and cytokine signals enhance TCR-based cell therapies https://www.biorxiv.org/content/10.64898/2026.07.12.738084v1

Quorum sensing underlies the establishment and maintenance of marginal zone B cells https://www.biorxiv.org/content/10.64898/2026.07.11.737964v1

Weight loss increases adipose dendritic cells, non-classical antigen presenting proteins, and cytotoxic effector cells https://www.biorxiv.org/content/10.64898/2026.07.13.738291v1

The NBSGW RIP-DTR Mouse: An Integrated Platform for Diabetes Induction, Human Immune Reconstitution and Transplantation Studies https://www.biorxiv.org/content/10.64898/2026.07.10.737744v1

Subunit vaccination enhances protection conferred by prior Mycobacterium tuberculosis exposure https://www.biorxiv.org/content/10.64898/2026.07.10.737547v1

Adaptive Resilience: Agarikon Mycelium Modulates Immune Responses and Provides Oxidative Stress Buffering in Human Immune Cells https://www.biorxiv.org/content/10.64898/2026.07.10.737773v1

Host-secreted lactate during respiratory viral infection diminishes macrophage antibacterial activity through metabolic reprogramming https://www.biorxiv.org/content/10.64898/2026.07.11.737940v1

Broad remodeling of the pulmonary immune landscape occurs during IAPA with specific functional deficits of neutrophil subsets https://www.biorxiv.org/content/10.64898/2026.07.10.737810v1

Assessment of polymeric immunoglobulin A and M via detection of the joining chain https://www.biorxiv.org/content/10.64898/2026.07.14.737820v1

IL-27 Signaling Protects Against Influenza-Associated Pulmonary Aspergillosis Through Inhibition of Type 2 Immunity and Enhanced Antifungal Immunity https://www.biorxiv.org/content/10.64898/2026.07.10.737799v1

Maternal vaccination timing shapes the composition and maturation of antibody clonotypes transferred to the newborn https://www.biorxiv.org/content/10.64898/2026.07.13.738171v1

ARID3a-Expressing Naive B Cells in SLE have an Activated Phenotype and Transiently Express Surface CD68 https://www.biorxiv.org/content/10.64898/2026.07.10.737835v1

Ageing of the Upper Airway Epithelial Niche Limits Tissue-Resident T Cell Immunity https://www.biorxiv.org/content/10.64898/2026.07.10.737724v1

SIGLEC1 FACILITATES MACROPHAGE-CD8+ T CELL INTERACTIONS AND CORRELATES WITH CANCER IMMUNOTHERAPY RESPONSE https://www.biorxiv.org/content/10.64898/2026.07.09.737484v1

The CD19-4-1BBL antibody fusion protein unleashes the immune system against high-risk chronic lymphocytic leukemia https://www.biorxiv.org/content/10.64898/2026.07.09.737515v1

LARP4 is a B cell-specific metabolic checkpoint for plasma cell differentiation and a therapeutic target in systemic lupus erythematosus https://www.biorxiv.org/content/10.64898/2026.07.10.737704v1

The paraspeckle protein NONO potentiates the antiviral innate immune response through chromatin regulation https://www.biorxiv.org/content/10.64898/2026.07.11.737985v1

The UPRMT is a critical mediator of nutrient immunity https://www.biorxiv.org/content/10.64898/2026.07.11.737880v1

Long dsRNA on the move: Extracellular vesicles deliver dsRNA for antiviral protection in human cells https://www.biorxiv.org/content/10.64898/2026.07.09.737430v1

A preliminary study of HMGB1 defense in Crohn's disease https://www.biorxiv.org/content/10.64898/2026.07.09.737505v1

Generation of hypoimmunogenic gastric insulin-secreting organoids https://www.biorxiv.org/content/10.64898/2026.07.08.736836v1

IL-21-producing peripheral helper T cells associate with autoimmune bile duct injury in biliary atresia https://www.biorxiv.org/content/10.64898/2026.07.08.736942v1

Multi-omics integration identifies a reproducible inflammatory host-response axis in pediatric sepsis https://www.biorxiv.org/content/10.64898/2026.07.06.736269v1

Learned Immune Architectures of Durable Antibody Responses Across Vaccines https://www.biorxiv.org/content/10.64898/2026.07.08.737303v1

Inflammatory endothelial cells promote infiltration of antigen-licensed cytotoxic T cells in malignant gliomas after irradiation https://www.biorxiv.org/content/10.64898/2026.07.08.737259v1

Oral Administration of Hyperimmune Eggs Induces Mucosal IgA Responses, Anti-Idiotypic Antibodies, and HIV-1 Neutralizing Activity: A Proof-of-Concept Preclinical Study https://www.biorxiv.org/content/10.64898/2026.07.04.736505v1

Synovium-Restricted Armored PD-1-Targeted CAR-T Cells Reprogram Immunity and Resolve Experimental Arthritis https://www.biorxiv.org/content/10.64898/2026.07.09.737520v1

Lipid chlorination mobilizes Neutrophil Elastase to initiate NETosis https://www.biorxiv.org/content/10.64898/2026.07.07.737103v1

Intrinsic T-cell programming and immune spatial organization govern sex-biased tuberculosis immunity https://www.biorxiv.org/content/10.64898/2026.07.07.737119v1

A Donor T-Cell Receptor Structural Signature Determines Alloreactive Potential and Predicts Acute Graft-Versus-Host Disease https://www.biorxiv.org/content/10.64898/2026.07.08.737087v1

Limitations of EBV transformed human Raji B cells as a model for measuring canonical NF-κB activation https://www.biorxiv.org/content/10.64898/2026.07.07.737082v1

Mycobacterium tuberculosis Δlsr2 Vaccine Enhances Protection Against Tuberculosis https://www.biorxiv.org/content/10.64898/2026.07.07.737086v1

Tricuspid valve regurgitation accelerates heart failure via a cardio-intestinal innate immune circuit https://www.biorxiv.org/content/10.64898/2026.07.07.736969v1

A transcriptional continuum links viral burden and host-cell biology in human lymphoid tissue https://www.biorxiv.org/content/10.64898/2026.07.07.736525v1

E-cadherin maintains oral Langerhans cell barrier surveillance to preserve microbiota-dependent immune homeostasis https://www.biorxiv.org/content/10.64898/2026.07.07.736593v1

AI-Informed neoantigen prioritization enables a multi-epitope mRNA/LNP vaccine with antigen-specific immunogenicity and antitumor activity https://www.biorxiv.org/content/10.64898/2026.07.06.736667v1

Restricted MHC-II trafficking in Mycobacterium tuberculosis-infected M2-like macrophages limits CD4+ T cell activation https://www.biorxiv.org/content/10.64898/2026.07.07.736943v1

Molecular-level analysis of serum IgG repertoires in COVID-19-vaccinated people with cystic fibrosis identifies abundant convergent antibodies https://www.biorxiv.org/content/10.64898/2026.07.08.737356v1

The RLR-MAVS-IRF3 axis activates the IFN pathway to restrict Tonate virus (TONV) infection https://www.biorxiv.org/content/10.64898/2026.07.09.737427v1

Akkermansia muciniphila-derived LPS links gut dysbiosis to pathogenic miR-21 signaling in experimental autoimmune encephalomyelitis. https://www.biorxiv.org/content/10.64898/2026.07.06.736880v1

Cannabinoid CB2 receptor activation drives glucose uptake, shifting T cell metabolism. https://www.biorxiv.org/content/10.64898/2026.07.07.736985v1

Ebola virus exploits host lncRNA LINC01740 to enhance ATF3 and suppress antiviral immune responses https://www.biorxiv.org/content/10.64898/2026.07.06.731958v1

Bulk and single-cell transcriptomics reveal elevated endogenous retrovirus expression linked to immunopathology in severe COVID-19. https://www.biorxiv.org/content/10.64898/2026.07.08.737320v1

Tumour microenvironments impose translational repression that limits natural killer cell persistence https://www.biorxiv.org/content/10.64898/2026.07.06.736719v1

Coordinated expansion of CD163⁺ monocytes and immature CD177⁺ neutrophils marks severe neurotoxicity after CD19 CAR T cell therapy https://www.biorxiv.org/content/10.64898/2026.07.07.737099v1

Inhibition of integrin αvβ8-mediated TGFβ activation and active-TGFβ blockade promote anti-tumor immunity through distinct biological mechanisms https://www.biorxiv.org/content/10.64898/2026.07.06.735099v1