Insulin deficiency inhibits vaccine-mediated antibody and germinal center B-cell formation in mice. https://www.biorxiv.org/content/10.1101/2025.09.24.677144v1

Staphylococcus aureus inhibits the NLRP3 inflammasome in macrophages during the early phases of intracellular infection, but not the late phases https://www.biorxiv.org/content/10.1101/2025.09.24.678325v1

The adhesion molecules β7 integrin and L-selectin contribute to cholestatic liver disease in male mice https://www.biorxiv.org/content/10.1101/2025.09.24.678237v1

NTX250: A Modular mRNA-Based Immunotherapy Platform for HPV-Associated Cancers with Broad Applicability. https://www.biorxiv.org/content/10.1101/2025.09.24.678202v1

Childhood brain tumours instruct cranial haematopoiesis and immunotolerance https://www.biorxiv.org/content/10.1101/2025.09.25.678472v1

Wall teichoic acid is required for DNA-triggered innate immune receptor activation by Staphylococcus aureus https://www.biorxiv.org/content/10.1101/2025.09.25.678139v1

SARS-CoV-2 ORF7a Drives Mitochondrial Dysfunction via PDK4 Activation and Complex I Inhibition https://www.biorxiv.org/content/10.1101/2025.09.25.678549v1

Uterine immune dysregulation after asynchronous transfer induced embryonic apoptosis in mice https://www.biorxiv.org/content/10.1101/2025.09.24.677934v1

Longitudinal profiling of tumor-reactive T cells during TIL therapy in metastatic melanoma https://www.biorxiv.org/content/10.1101/2025.09.23.678066v1

Characterization of the TREM-1 Signaling Landscape in Human Neutrophils https://www.biorxiv.org/content/10.1101/2025.09.23.678160v1

Senataxin is required for optimal class switch recombination to the immunoglobulin A isotype https://www.biorxiv.org/content/10.1101/2025.09.23.678005v1

Oral L-arginine cures arginase 1-dependent chronic cutaneous leishmaniasis by redirecting the T helper cell response https://www.biorxiv.org/content/10.1101/2025.09.23.677696v1

TWEAK is increased in ulcerative colitis and contributes to fibroblast-mediated monocyte activation via heterologous non-canonical NF-kB/STAT3 signalling https://www.biorxiv.org/content/10.1101/2025.09.23.678006v1

Epithelial-intrinsic nitric oxide synthase 2 sustains host-microbiota dynamics that promote colitis https://www.biorxiv.org/content/10.1101/2025.09.23.677925v1

IFNAR1. Neutrophils Orchestrate Chronic Inflammatory Damage Through Mitochondrial Remodeling https://www.biorxiv.org/content/10.1101/2025.09.22.677957v1

A data-driven model of macrophage polarization states reveals an IFN macrophage signature in active Crohn's disease https://www.biorxiv.org/content/10.1101/2025.09.24.678388v1

Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases https://www.biorxiv.org/content/10.1101/2025.09.23.677874v1

Potentiating CAR-T bystander killing by enhanced Fas/FasL signaling mitigates antigen escape in heterogeneous tumors https://www.biorxiv.org/content/10.1101/2025.09.22.677496v1

The anti-virus T cell response dominates the anti-cancer response in oncolytic virus therapy https://www.biorxiv.org/content/10.1101/2025.09.22.677905v1

Regulation of TCR-induced Transcriptional Kinetics by Interleukin 2-inducible T Cell Kinase (ITK) in CD8+ T cells https://www.biorxiv.org/content/10.1101/2025.09.22.677398v1

IRF2 degradation tunes the innate immune response https://www.biorxiv.org/content/10.1101/2025.09.23.678148v1

In vivo genome-wide CRISPR screens in human T cells to enhance T cell therapy for solid tumors https://www.biorxiv.org/content/10.1101/2025.09.23.678127v1

A Novel dual Influenza virus and SARS-CoV-2 neutralisation assay https://www.biorxiv.org/content/10.1101/2025.09.19.677384v1

Redirection of SARS-CoV-2 to phagocytes by intranasal sACE2-Fc as a universal decoy confers complete prophylactic protection https://www.biorxiv.org/content/10.1101/2025.09.23.677998v1

Altered MicroRNA Signatures in Circulating Extracellular Vesicles Reflect Aortic Dilation in Takayasu Arteritis https://www.biorxiv.org/content/10.1101/2025.09.21.677656v1

An atlas of natural killer cell receptor expression on healthy donor T and NK lymphocytes https://www.biorxiv.org/content/10.1101/2025.09.21.677654v1

Optimized Ex Vivo Differentiation of CD103⁺ Dendritic Cells and High-Efficiency Retroviral Transduction of Mouse Bone Marrow HSCs https://www.biorxiv.org/content/10.1101/2025.09.21.677651v1

Mechanisms of superior respiratory IgA responses against SARS-CoV-2 after mucosal vaccination https://www.biorxiv.org/content/10.1101/2025.09.22.677712v1

Upd-like/JAK/STAT signaling promotes regeneration and tolerance to bacterial infection in the Aedes midgut https://www.biorxiv.org/content/10.1101/2025.09.21.677592v1

Bicistronic CAR T-cells Against CD70 & Active Integrin β2 Overcome Antigen Heterogeneity and Preserve Safety in Acute Myeloid Leukemia https://www.biorxiv.org/content/10.1101/2025.09.21.677627v1

Dual-Route H5N1 Vaccination Induces Systemic and Mucosal Immunity in Murine and Bovine Models https://www.biorxiv.org/content/10.1101/2025.09.21.677614v1

Chemotherapy Induces an IL1β-dependent Neutrophil Recruitment that Promotes Chemoresistance in Metastatic Ovarian Cancer https://www.biorxiv.org/content/10.1101/2025.09.21.677600v1

GATHeR: Graph-based Accurate Tool for Immunoglobulin HEavy- and Light-chain Reconstruction https://www.biorxiv.org/content/10.1101/2025.09.21.677530v1

Predicting Risk of Transfusion-Induced Red Blood Cell Alloimmunization Using Statistical and Machine Learning Approaches in the Recipient Epidemiology and Donor Evaluation Study (REDS-III) Database https://www.biorxiv.org/content/10.1101/2025.09.21.677587v1

Effective allogeneic natural killer cell therapy for pancreatic adenocarcinoma avails conserved activating receptors and evades HLA I-driven inhibition https://www.biorxiv.org/content/10.1101/2025.09.21.677560v1

In vitro and in vivo derived macrophages occupy distinct phenotypic states https://www.biorxiv.org/content/10.1101/2025.09.20.677495v1

HIV Env trimers elicit NHP apex cross-neutralizing antibodies mimicking human bNAbs https://www.biorxiv.org/content/10.1101/2025.09.19.677470v1

ILC3 inhibits Osteoclastogenesis and ameliorates Inflammatory Bone Loss in Post-menopausal Osteoporosis https://www.biorxiv.org/content/10.1101/2025.09.20.677486v1

Single-Cell Atlas of CD4+ T-Helper 2 Cells Reveals Distinct Cytokine Functions Across Diseases https://www.biorxiv.org/content/10.1101/2025.09.20.677532v1

Fetal and maternal immune cells exhibit tandem maturation across gestation and dysregulation in preterm birth https://www.biorxiv.org/content/10.1101/2025.09.20.677440v1

Dexamethasone inhibits the LPS-induced activation of hypoxia-inducible factor 1 alpha (HIF-1α) in macrophages independently of the DUSP1-p38-TTP-HIF-1α regulatory axis. https://www.biorxiv.org/content/10.1101/2025.09.19.677372v1

The structures of tetrameric Avian Immunoglobulin A are uniquely structured to support mucosal immunity https://www.biorxiv.org/content/10.1101/2025.09.19.677352v1

Dynamics of Macrophage Polarization Reveal Unique Phenotypes During Mouse Postpartum Uterine Remodeling https://www.biorxiv.org/content/10.1101/2025.09.19.676950v1

Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair https://www.biorxiv.org/content/10.1101/2025.09.19.677333v1

In vitro effects of selected angiogenesis-promoting drugs on human Ea.hy926 endothelial cells treated with critical-stage dengue hemorrhagic fever serum https://www.biorxiv.org/content/10.1101/2025.09.19.677322v1

Divergent Macrophage-Regulated T cell States Determine Response to Bacillus Calmette-Guerin (BCG) in High-Risk Bladder Cancer https://www.biorxiv.org/content/10.1101/2025.09.18.677132v1

Beyond Sequence Similarity: ML-Powered Identification of pHLA Off-Targets for TCR-Mimic Antibodies Using High Throughput Binding Kinetics https://www.biorxiv.org/content/10.1101/2025.09.19.677256v1

Lower Airway Dysbiosis in NTM+ Bronchiectasis is Associated with NET-Predominant Severe Phenotypes https://www.biorxiv.org/content/10.1101/2025.09.18.677189v1

NK cells undergo transcriptional and functional reprogramming following Streptococcus pneumoniae infection https://www.biorxiv.org/content/10.1101/2025.09.19.677332v1

Long-lived IgE plasma cells that reside in the spleen contribute to the persistence of the IgE response https://www.biorxiv.org/content/10.1101/2025.09.18.676877v1