Targeting C5aR1 Reveals Protective Macrophage Maturation States in Intestinal Injury https://www.biorxiv.org/content/10.1101/2025.11.11.687632v1

Unraveling IGK Locus in Dog Breeds: IMGT(R) New Insights into Canine Immunogenetics. https://www.biorxiv.org/content/10.1101/2025.11.10.687733v1

An AI-driven approach for nanobody affinity maturation https://www.biorxiv.org/content/10.1101/2025.11.11.687768v1

Natural killers in pregnancy: servants of two masters https://www.biorxiv.org/content/10.1101/2025.11.11.685990v1

Isolation of functional supramolecular attack particles (SMAPs) https://www.biorxiv.org/content/10.1101/2025.11.10.687675v1

Sensory neuronal mTORC1 signaling establishes neuroimmune memory that initiates allergic immunity https://www.biorxiv.org/content/10.1101/2025.11.10.687723v1

Multi-omics identification of activated T cells and spatial PD-1/PD-L1 signaling as biomarkers of diabetic foot ulcer healing https://www.biorxiv.org/content/10.1101/2025.11.10.687697v1

Hydroxychloroquine decouples reactogenicity from efficacy in mRNA and viral-vector gene delivery https://www.biorxiv.org/content/10.1101/2025.11.10.687670v1

Intrathymic progenitor cell transplantation restores T cell development through ILC3-TEC crosstalk https://www.biorxiv.org/content/10.1101/2025.11.10.687563v1

Modulation of Neutrophil Function by Foetal Bovine Serum and Type I Collagen https://www.biorxiv.org/content/10.1101/2025.11.10.687474v1

Dual human lung models reveal compartment-specific activity of anti-tuberculosis drugs and host-directed therapies https://www.biorxiv.org/content/10.1101/2025.11.10.685269v1

High Precision Peptide-MHC Class I CARs Enhance In Vivo Killing ofTargeted CD8 T Cells to Prevent Type 1 Diabetes in Novel RIP-mOVA Model https://www.biorxiv.org/content/10.1101/2025.11.10.687586v1

Inflammatory Agonists Modulate the Host Response to Type 2 ECM scaffold Immune Environment and Long-Term Remodeling After Severe Traumatic Injury https://www.biorxiv.org/content/10.1101/2025.11.09.687444v1

A Triple-Hit Alcoholic Liver Disease Model Linking High-Fat Diet, Endotoxins, and Neo-Antigen Formation https://www.biorxiv.org/content/10.1101/2025.11.10.687007v1

A BCG toxic effector induces mitochondrial DNA compaction to refrain protective immunity https://www.biorxiv.org/content/10.1101/2025.11.09.687409v1

Alternative Splicing And Global Transcriptome Changes Associated With LPS Stimulation In Human Peripheral Blood Mononuclear Cells https://www.biorxiv.org/content/10.1101/2025.11.09.687437v1

Multiple broadly neutralizing antibody lineages can co-exist and mature in the same germinal centres https://www.biorxiv.org/content/10.1101/2025.11.09.687328v1

T-Cell Synaptosomes Orchestrate Long-Term Anti-Tumor Immunity via Proliferative and Metabolic Reprogramming https://www.biorxiv.org/content/10.1101/2025.11.06.687075v1

Spatial transcriptomics reveals distinct inflammatory and adaptive immune properties of rheumatoid arthritis synovial fibroblasts https://www.biorxiv.org/content/10.1101/2025.11.08.687060v1

Truncating RELA variants drive autoinflammation and autoimmunity by impairing the negative feedback control of NF-kB https://www.biorxiv.org/content/10.1101/2025.11.09.687461v1

Meningeal γδ T cells facilitate bacterial entry into the brain in neonatal meningitis and trigger long-term behavioural sequelae https://www.biorxiv.org/content/10.1101/2025.11.07.686929v1

Coordinated circulating and tissue-based T cell responses precede xenograft rejection https://www.biorxiv.org/content/10.1101/2025.11.07.687259v1

Escherichia coli-induced gut IL-33 release inhibits lung type 2 allergic responses https://www.biorxiv.org/content/10.1101/2025.11.07.687219v1

Structure basis for distinct protective mechanisms of IGHV3-23 antibodies targeting influenza hemagglutinin stem https://www.biorxiv.org/content/10.1101/2025.11.06.687086v1

Antibodies, Memory B Cells, and Antigen Valency Reshape B Cell Responses to Drifted Influenza Virus Vaccination https://www.biorxiv.org/content/10.1101/2025.11.07.687210v1

Structure-based engineering of a nutrient acquisition protein enhances neutralizing antibodies and protection for the development of a gonococcal vaccine https://www.biorxiv.org/content/10.1101/2025.11.06.685839v1

T cell fate is dictated by different antigen presenting cells in response to dietary versus gut epithelial self-antigen https://www.biorxiv.org/content/10.1101/2025.11.06.687030v1

NF-kB-Dependent Transcriptional Regulation of Piezo1 Mediates Bacterial Clearance on Stiffened Lung https://www.biorxiv.org/content/10.1101/2025.11.06.687026v1

Antibody-mediated feedback modulates interclonal competition in the germinal center https://www.biorxiv.org/content/10.1101/2025.11.06.686519v1

Immune transcriptomic differences in paediatric patients with SARS-CoV-2 compared to other lower respiratory tract infections https://www.biorxiv.org/content/10.1101/2025.11.07.687132v1

Human Norovirus NS7 Protein Activates Canonical Inflammasome Pathways via NLRP6 in Intestinal Epithelial Cells https://www.biorxiv.org/content/10.1101/2025.11.07.687139v1

Non-Enzymatic Structural Modifications Reshape Peptide Presentation and Antigen Recognition https://www.biorxiv.org/content/10.1101/2025.11.06.687013v1

Retargeted adenoviruses for local IgA and CD47 blocker production as a novel cancer therapy https://www.biorxiv.org/content/10.1101/2025.11.07.686998v1

Dysregulation of U12-Type Splicing in Lupus Neutrophils https://www.biorxiv.org/content/10.1101/2025.11.06.686965v1

Flagellin-mediated TLR5 activation enhances innate immune responses in healthy and diseased human airway epithelium https://www.biorxiv.org/content/10.1101/2025.11.06.686934v1

The conserved bridging domain on HCV E1E2 glycoprotein complex is targeted by neutralizing antibodies from diverse lineages https://www.biorxiv.org/content/10.1101/2025.11.05.686883v1

Tumors Located in the Brain Impair the Frequency and Phenotype of Dendritic Cells in Blood and Tumor https://www.biorxiv.org/content/10.1101/2025.11.05.686441v1

Human coronavirus HKU1 neutralization by glycan receptor mimicry https://www.biorxiv.org/content/10.1101/2025.11.05.686863v1

Macrophage chemotaxis steered by complex self-generated gradients of complement C5a https://www.biorxiv.org/content/10.1101/2025.11.05.686842v1

Display of clustered antigen by follicular dendritic cells tunes B-cell receptor activation https://www.biorxiv.org/content/10.1101/2025.11.05.686827v1

Atomistic TCR-ligand interactions instruct memory T-cell differentiation https://www.biorxiv.org/content/10.1101/2025.11.05.686789v1

Persistent Activation of Monocytes/Macrophages and Cell Senescence in SIV-Infected Macaques on ART https://www.biorxiv.org/content/10.1101/2025.11.05.686810v1

Identification of Protein Cargo in Extracellular Vesicles from Macrophages in Progressing and Regressing Tumors https://www.biorxiv.org/content/10.1101/2025.11.05.685429v1

Stenocytosis: a mechanism for supramolecular attack particle transfer at the CTL lytic synapse https://www.biorxiv.org/content/10.1101/2025.11.05.686769v1

Chicken IRF10 suppresses the cGAS-STING-IFN antiviral signaling pathway by targeting IRF7 https://www.biorxiv.org/content/10.1101/2025.11.05.686717v1

Exploring the neuroimmune cellular landscape in the skin of subjects with fibromyalgia. https://www.biorxiv.org/content/10.1101/2025.11.05.686713v1

Brain defence by the extracellular matrix protein Cochlin https://www.biorxiv.org/content/10.1101/2025.11.05.686104v1

Sox4 in Treg Cells Suppresses IL-10 Production via c-Maf Degradation and Exacerbates Type 2 Inflammation https://www.biorxiv.org/content/10.1101/2025.11.04.686669v1

Bispecific CD20xCD40 Antibodies Achieve Multi-Lineage Modulation of Humoral and Cellular Immunity https://www.biorxiv.org/content/10.1101/2025.11.04.686640v1

Iterative immunogen optimization to focus elicited responses on a conserved, subdominant influenza hemagglutinin epitope https://www.biorxiv.org/content/10.1101/2025.11.04.686334v1