Maternal Western-style Diet Promotes Immune Tolerance and Liver Sinusoidal Endothelial Cell Dysfunction in Nonhuman Primate Juvenile Offspring Liver https://www.biorxiv.org/content/10.64898/2026.01.06.697995v1

Single-antibody mutational scanning reveals poly-specificity and immune constraints in vaccination responses https://www.biorxiv.org/content/10.64898/2026.01.07.697678v1

Phenotypic dynamics and behaviors of neutrophils during barrier challenge https://www.biorxiv.org/content/10.64898/2026.01.06.697946v1

Natural H5N1 immunity in dairy cows is durable and cross-protective but non-sterilizing https://www.biorxiv.org/content/10.64898/2026.01.06.697911v1

A rhinovirus vaccine evokes T cell mediated cross-reactive immunity in a preclinical model of rhinovirus infection https://www.biorxiv.org/content/10.64898/2026.01.06.697896v1

mAbClust with AlphaFold 3 avoids hallucinations to define a quaternary broadly neutralizing HCV epitope https://www.biorxiv.org/content/10.64898/2026.01.06.698032v1

Interrogating antiviral antibody responses with multiplexed, high-throughput serum assays https://www.biorxiv.org/content/10.64898/2026.01.03.697501v1

A plant virus-based virus like-particle platform for therapeutic vaccination targeting IL-23A https://www.biorxiv.org/content/10.64898/2026.01.06.697872v1

Mettl3-catalyzed m6A methylation determines CD8+ T cell differentiation fate in tumor https://www.biorxiv.org/content/10.64898/2026.01.06.697843v1

Regulatory T cells clonally expand and contribute to stromal cell function in fibrotic response to synthetic implants https://www.biorxiv.org/content/10.64898/2026.01.05.697727v1

A New Paradigm for the Mathematical Modelling of Multiple Sclerosis https://www.biorxiv.org/content/10.64898/2026.01.04.697229v1

Second-order regulation: IFN-γ suppresses IL-17A-mediated neutrophilic inflammation. https://www.biorxiv.org/content/10.64898/2026.01.05.697792v1

Spatiotemporal Mapping of Tertiary Lymphoid Structure Heterogeneity Shapes Immune Niches and Clinical Outcomes in Intrahepatic Cholangiocarcinoma https://www.biorxiv.org/content/10.64898/2026.01.02.697439v1

Subunit Vaccination Using Atomic Layering Thermostable Antigen and Adjuvant (ALTA(R)) Platform Elicits Enhanced Humoral and Cellular Immune Responses https://www.biorxiv.org/content/10.64898/2026.01.05.697739v1

Salmonella SPI2 evades detection by NAIP/NLRC4 despite utilization of a detectable needle https://www.biorxiv.org/content/10.64898/2026.01.05.696446v1

Atomic Layering Thermostable Antigen and Adjuvant (ALTA(R)) platform provides unique antigen delivery system through controlled release to improve immune response to vaccination https://www.biorxiv.org/content/10.64898/2026.01.05.697591v1

Characterizing cellular subpopulations critical to treatment response in autoimmune diseases https://www.biorxiv.org/content/10.64898/2026.01.05.696211v1

Targeted Lipid Metabolism Screening Uncovers Regulatory Effects on the STING Immune Response in Mevalonate, Eicosanoid and Fatty Acid Pathways https://www.biorxiv.org/content/10.64898/2026.01.05.697750v1

O-GlcNAcylation drives macrophage IL-4 responsiveness and tissue residency through metabolic and cell cycle calibration https://www.biorxiv.org/content/10.64898/2026.01.05.697622v1

Awakening intracellular immunity for functional HIV cure https://www.biorxiv.org/content/10.64898/2026.01.04.697570v1

Molecular and biophysical requirements for B cell receptor dependent enhancement of dengue virus infection https://www.biorxiv.org/content/10.64898/2026.01.05.697627v1

Spatial transcriptomic analysis of myositis muscles reveals novel molecular insights of MDA5+ dermatomyositis https://www.biorxiv.org/content/10.64898/2026.01.04.696800v1

Leveraging TNFR2 for antitumour immunity: T reg depletion and myeloid reprogramming versus T cell costimulation https://www.biorxiv.org/content/10.64898/2026.01.04.697572v1

An additional site mutation in MITA/STING gain-of-function mutants abolishes the autoimmune SAVI phenotypes and directs a therapeutic strategy. https://www.biorxiv.org/content/10.64898/2026.01.03.697515v1

Sub-neutralizing concentrations of Zika virus IgM monoclonal antibodies reduce IgG-mediated antibody-dependent enhancement of infectivity. https://www.biorxiv.org/content/10.64898/2026.01.03.697490v1

Putative target antigens of the stereotyped intrathecal B cell response in multiple sclerosis https://www.biorxiv.org/content/10.64898/2026.01.03.697481v1

ABCC1 protects skin dendritic cells from FITC-induced toxicity by efflux and extracellular glutathione buffering https://www.biorxiv.org/content/10.64898/2026.01.02.697391v1

Interplay between the immune response and the adaptation of metabolic pathways upon infection https://www.biorxiv.org/content/10.64898/2026.01.02.697260v1

Post-COVID impairment of memory T cell responses to community-acquired pathogens can be rectified by activating cellular metabolism https://www.biorxiv.org/content/10.64898/2025.12.31.697156v1

CAR-T-drug conjugate against solid tumor https://www.biorxiv.org/content/10.64898/2026.01.02.696502v1

A Glycosylation-Dependent Checkpoint Restrains Intestinal Intra-Epithelial Lymphocyte Activation https://www.biorxiv.org/content/10.64898/2026.01.02.697332v1

Natural killer cells mediated antibody dependent cellular cytotoxicity response in acute and recovery phases of chikungunya https://www.biorxiv.org/content/10.64898/2026.01.01.697330v1

Tumor-infiltrating natural killer cell profiling for therapeutic stratification in patients with resectable non-small cell lung cancer https://www.biorxiv.org/content/10.64898/2026.01.01.696292v1

Single-cell characterization and machine learning-based classification reveal the transcriptional identity and antigen-experienced features of peripheral CD4+CD8+ double-positive T cells https://www.biorxiv.org/content/10.64898/2026.01.01.697324v1

State-Dependent Regulatory Compression: Chromatin Geometry Gates Information Flow in Hematopoiesis https://www.biorxiv.org/content/10.64898/2025.12.31.697240v1

TMEM33 deletion potentiates anti-tumor CD8+ T cell immunity https://www.biorxiv.org/content/10.64898/2026.01.01.697288v1

Proton-Activated Chloride Channel 1 (PACC1) is essential for innate host defense against bacterial sepsis https://www.biorxiv.org/content/10.64898/2025.12.31.697179v1

Smad7-based biologic targeting epidermis and stroma promotes healing of diabetic wounds in mice and pigs https://www.biorxiv.org/content/10.64898/2025.12.31.697220v1

Fezf2 regulates differentiation of Aire-expressing and post-Aire mimetic epithelial populations maintaining thymic homeostasis https://www.biorxiv.org/content/10.64898/2025.12.31.697099v1

State-dependent geometric constraints reveal a regulatory gate in hematopoietic progenitors https://www.biorxiv.org/content/10.64898/2025.12.31.697210v1

Mucosally sourced complement factor B modulates the host response to colitis https://www.biorxiv.org/content/10.64898/2025.12.31.697141v1

Multi-omic analysis reveals nitric oxide dependent remodeling in classically activated macrophages and identifies negative regulation mediated by AKR1A1 https://www.biorxiv.org/content/10.64898/2025.12.31.697202v1

Development and application of nbLIBRA-seq for high-throughput discovery of antigen-specific nanobodies https://www.biorxiv.org/content/10.64898/2025.12.30.697047v1

Discover Potential New Epitopes through Post Translational Modification in Sjogrens Disease https://www.biorxiv.org/content/10.64898/2025.12.30.697079v1

Molecular Mechanisms of Priming Innate Immunity by Small Extracellular Vesicles Released during Infection with Gram-negative Bacteria https://www.biorxiv.org/content/10.64898/2025.12.30.697125v1

Impact of Absent in Melanoma 2 (AIM2) on Antigen-Specific CD4+ T cell Activation and Homeostasis. https://www.biorxiv.org/content/10.64898/2025.12.30.697014v1

Regulation of STING activation by phosphoinositide and cholesterol https://www.biorxiv.org/content/10.64898/2025.12.29.696921v1

SLAMF1-peptide mediated epigenetic priming reprograms innate immune responses in sepsis https://www.biorxiv.org/content/10.64898/2025.12.29.696918v1

Decoy Antibodies Block Extracellular HSP70, Prevent Self Signaling and Inhibit Melanoma Cell Survival https://www.biorxiv.org/content/10.64898/2025.12.29.696857v1

Cross-sectional association study from NHANES between some dietary supplements and anti-HAV antibodies https://www.biorxiv.org/content/10.64898/2025.12.29.696889v1