bioRxiv Immunology
@biorxiv-immuno.bsky.social
📤 5130
📥 0
📝 5174
A new humanized TCR transgenic mouse model to study citrullinated tenascin C reactive T cells relevant to rheumatoid arthritis
https://www.biorxiv.org/content/10.64898/2026.02.12.705563v1
about 3 hours ago
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Hyperglycemia promotes maladaptive Dectin-1 signaling and impairs skin antifungal host defense.
https://www.biorxiv.org/content/10.64898/2026.02.11.705431v1
about 18 hours ago
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Elevated ferritin as a companion biomarker of myeloid-driven inflammation in RNP/Sm co-positive, treatment-resistant SLE endotype
https://www.biorxiv.org/content/10.64898/2026.02.12.705402v1
about 18 hours ago
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Implantation failure linked to altered uterine NK cells in PCOS-like mice
https://www.biorxiv.org/content/10.64898/2026.02.12.705498v1
about 19 hours ago
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MONOCYTES STRONGLY INDUCE (MYO)FIBROBLAST CONTRACTION IN A NEW 3D SKIN MODEL TO UNDERSTAND THE INFLAMMATION-FIBROSIS AXIS IN SYSTEMIC SCLEROSIS
https://www.biorxiv.org/content/10.64898/2026.02.12.705496v1
about 19 hours ago
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TCR signal strength determines Treg instability and discrimination of self versus non-self antigens
https://www.biorxiv.org/content/10.64898/2026.02.12.705537v1
about 19 hours ago
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1
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Prolonged TGF-β locks NK cells in a dysfunctional state through persistent epigenetic remodeling of IRF, T-bet and EOMES binding sites
https://www.biorxiv.org/content/10.64898/2026.02.11.705354v1
about 21 hours ago
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Glucose-Responsive CD20+ Cytotoxic T Cells: A Novel Pro-inflammatory Mediator in the Immunopathogenesis of Type 2 Diabetes
https://www.biorxiv.org/content/10.64898/2026.02.12.705577v1
about 22 hours ago
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IFN-driven lipid synthesis shutdown in CD4⁺ T cells during acute SIV infection and persistent OXPHOS with ART initiation
https://www.biorxiv.org/content/10.64898/2026.02.12.705596v1
about 22 hours ago
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Evolutionary Divergence and Structural Differentiation of Multiple Immunoglobulin M Genes in Gekkota (Squamata: Reptilia)
https://www.biorxiv.org/content/10.64898/2026.02.13.705754v1
about 23 hours ago
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Deletion of NLRP3 gene blocks traumatic brain injury induced abnormal immune response in 3xTg AD mice
https://www.biorxiv.org/content/10.64898/2026.02.11.705384v1
about 23 hours ago
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A JAK-STAT-activated myeloid hub at ulceration sites underlies resistance to anti-TNF therapy in Crohn's disease
https://www.biorxiv.org/content/10.64898/2026.02.12.705345v1
about 23 hours ago
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Generative AI Guided Design of High-Affinity T cell Receptors
https://www.biorxiv.org/content/10.64898/2026.02.12.705547v1
2 days ago
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Mapping Tissue-Specific Protease Dynamics in the Pig Respiratory Tract During Influenza A Virus Infection
https://www.biorxiv.org/content/10.64898/2026.02.11.705325v1
2 days ago
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Macrophage renewal in the small intestine governs early-life control of streptococci
https://www.biorxiv.org/content/10.64898/2026.02.11.705249v1
2 days ago
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Elimination of intramuscular immunoglobulin accumulation alleviates Duchenne Muscular Dystrophy
https://www.biorxiv.org/content/10.64898/2026.02.11.703666v1
2 days ago
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EBV reprograms autoreactive B cells as antigen presenting cells in multiple sclerosis
https://www.biorxiv.org/content/10.64898/2026.02.11.701910v1
2 days ago
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Antibody-Dependent Heterotypic Syncytia Drive COVID-19 Inflammation and Disease Progression
https://www.biorxiv.org/content/10.64898/2026.02.11.705426v1
2 days ago
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Soluble LAG-3 Identifies a Dynamic Early T Cell Activation Window in self-reactivity, Type 1 Diabetes, and Broader Immune Responses.
https://www.biorxiv.org/content/10.64898/2026.02.10.705171v1
2 days ago
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Divergent disulfide bond architecture defines two IgY subclasses in snakes
https://www.biorxiv.org/content/10.64898/2026.02.11.705265v1
2 days ago
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Functional Equivalence of Heat-Inactivated (HI) and Live Probiotic RSB11 in Suppressing Inflammation: Expanding Formulation and Application Potential
https://www.biorxiv.org/content/10.64898/2026.02.11.705228v1
2 days ago
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Tumor-derived Extracellular Vesicles Induce ER Stress to Drive Tolerogenic Dendritic Cell Development in the Tumor Microenvironment
https://www.biorxiv.org/content/10.64898/2026.02.10.705213v1
2 days ago
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TCR Signal Strength and Eomes Coordinate CD8⁺ T Cell Fate and Antitumor Immunity in Hepatocellular Carcinoma
https://www.biorxiv.org/content/10.64898/2026.02.10.705135v1
2 days ago
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Spatial immune hubs defined by conserved activated dendritic cells are remodeled by immunotherapy
https://www.biorxiv.org/content/10.64898/2026.02.10.703136v1
3 days ago
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CD14-deficiency protects against osteoarthritic subchondral bone sclerosis via enhanced osteoclastogenesis following joint injury
https://www.biorxiv.org/content/10.64898/2026.02.10.705094v1
3 days ago
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RGS10 differently modulates NFκB subunit transcription and inflammatory cytokine profiles in peritoneal macrophages.
https://www.biorxiv.org/content/10.64898/2026.02.09.704897v1
3 days ago
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Multiplexed high-content imaging uncovers morphological diversity of lymphocyte activation and dysfunction
https://www.biorxiv.org/content/10.64898/2026.02.10.704860v1
3 days ago
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Base-resolution DNA methylome of human MDS hematopoietic stem cell reveals TET2-GFI1 epigenetic axis repressing MDS
https://www.biorxiv.org/content/10.64898/2026.02.10.704995v1
3 days ago
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A framework for reparative CAR T engineering in the CNS
https://www.biorxiv.org/content/10.64898/2026.02.09.703122v1
3 days ago
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Macrophage Phagocytic Impairment is associated with Dysbiosis of the Respiratory Microbiome in Frail older adults
https://www.biorxiv.org/content/10.64898/2026.02.09.703495v1
3 days ago
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Strength in Unity: a Dual Strategy to Restore NK Cell Cytotoxicity against Pancreatic Ductal Adenocarcinoma
https://www.biorxiv.org/content/10.64898/2026.02.09.704789v1
4 days ago
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Type I and Type III Interferons Differentially Shape Antiviral Defense and Epithelial Integrity at the Choroid Plexus
https://www.biorxiv.org/content/10.64898/2026.02.10.705109v1
4 days ago
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Platform-Imprinted Transcriptional and Clonal Remodeling of αβ and γδT Cells After Allogeneic Transplantation
https://www.biorxiv.org/content/10.64898/2026.02.09.704768v1
4 days ago
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Proteostasis sustains T cell differentiation potential and tumor-infiltrating lymphocyte function
https://www.biorxiv.org/content/10.64898/2026.02.08.704716v1
4 days ago
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1
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PDE4 Inhibitor Apremilast Rebalances Inflammatory Responses to Pseudomonas aeruginosa Infection in CF Rats
https://www.biorxiv.org/content/10.64898/2026.02.08.704692v1
4 days ago
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SERPINA3 and NDRG1 are critical diagnostic immune genes associated with macrophages in preeclampsia
https://www.biorxiv.org/content/10.64898/2026.02.09.704892v1
4 days ago
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1
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NINJ1 mediates hepatic ischemia-reperfusion injury
https://www.biorxiv.org/content/10.64898/2026.02.07.704585v1
5 days ago
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EBV Type 1 versus Type 2: A determinant of NK cell anti-tumor activity in Burkitt lymphoma
https://www.biorxiv.org/content/10.64898/2026.02.09.704808v1
5 days ago
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Serotypic heterogeneity in the response to pneumococcal vaccine
https://www.biorxiv.org/content/10.64898/2026.02.06.704301v1
5 days ago
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Early developmental placental defects and pregnancy loss in lupus mice expressing human TLR8
https://www.biorxiv.org/content/10.64898/2026.02.07.701591v1
5 days ago
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Divergent phenotypic and functional roles of human T follicular helper cells from infancy to adulthood
https://www.biorxiv.org/content/10.64898/2026.02.06.704464v1
5 days ago
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Innate Immune Function of Neutrophil Cytoplasts Generated Post-Vital NETosis
https://www.biorxiv.org/content/10.64898/2026.02.06.704503v1
5 days ago
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A KETOGENIC DIET PROMOTES BLOOD-SPINAL CORD BARRIER RESEALING AND PHENOTYPIC SWITCHING OF PRO-INFLAMMATORY MYELOID CELL INFILTRATES IN A PRECLINICAL MODEL OF MULTIPLE SCLEROSIS.
https://www.biorxiv.org/content/10.64898/2026.02.06.704406v1
5 days ago
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Multimodal Profiling of Repair-associated Immune Dynamics in a Mouse Model of Menstruation
https://www.biorxiv.org/content/10.64898/2026.02.06.704418v1
5 days ago
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Sheddase Targeting Chimeras (SHEDTACs) catalyze membrane target proteolysis
https://www.biorxiv.org/content/10.64898/2026.02.06.703938v1
5 days ago
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Extracellular vesicles from antigen-activated B cells stimulate oncogenic herpesvirus lytic gene expression
https://www.biorxiv.org/content/10.64898/2026.02.09.704805v1
5 days ago
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A Novel Secretome Rewrites the Immune Response in Viral Acute Respiratory Distress Syndrome
https://www.biorxiv.org/content/10.64898/2026.02.06.704035v1
5 days ago
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IFN gamma-induced IRF1 synergizes with TLR7 signals to tune the IRF4-IRF8 axis and drive pathogenic effector B cell fate
https://www.biorxiv.org/content/10.64898/2026.02.06.704376v1
5 days ago
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A spatiotemporal immune atlas of subarachnoid hemorrhage from single-cell and spatial transcriptomics
https://www.biorxiv.org/content/10.64898/2026.02.02.703421v1
6 days ago
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Crosstalk between Stromal cells and Macrophages Shapes Host Immunity to Mycobacteria
https://www.biorxiv.org/content/10.64898/2026.02.05.704052v1
6 days ago
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