Our paper out in Science today: The Metis defense system senses molecular byproducts released when a phage degrades the bacterial genome, and then prevents replication of the phage in the infected cell Congratulations @ostermanilya.bsky.social and co-authors!

Congrats Moshe, Sasha and team! @weizmann . Glad to see this out! A beautiful story showing how epithelial stem cells differentiate upon salmonella infection to adapt the tissue while maintaining the stem cells pool intact 👇🏻 www.nature.com/articles/s41...

To strengthen the European research on early life immunology we have started the EFIS study ELINE Info and seminar announcement 👇🏼 #EFIS#ELINE#immunology

Looking for motivated postdocs interested in doing exciting research at the intersection of immunology and regenerative biology. We use intravital two-photon imaging to track and manipulate immune cell behavior at the single-cell level in live animals mesa-lab.org Apply: apply.interfolio.com/180660

Overjoyed to share our new work exploring the antigen specificity of CSF-expanded CD8+ T cells in #multiplesclerosis #EBV in @natimmunol.nature.com #immunology 🧪🧵1/ www.nature.com/articles/s41...

Very happy to share our new study defining the ontogeny of Thetis cells and the developmental cues that shape their early-life wave of differentiation. www.nature.com/articles/s41... Beautiful work led by @hhmi-science.bsky.social Gilliam Fellow Yoselin Paucar Iza and postdoc Tyler Park 1/

Registration is open! @weizmanninstitute.bsky.social erez.weizmann.ac.il/apx/r/ws1/10...

As 2025 is drawing to a close, @jem.org would like to highlight all of the women who have contributed to the #WomenInSTEM #Viewpoint series over the last 3 years! Learn more about their scientific journeys on the path to independence here 👉 tinyurl.com/2wrxk4mk

Out now: We present antibody-lectin chimeras (AbLecs) as a molecular platform to target sugars, or glycans, for cancer immunotherapy. www.nature.com/articles/s41... www.nature.com/articles/s41... @mitkochinstitute.bsky.social @mitdeptofbe.bsky.social @mitcheme.bsky.social @stanford-chemh.bsky.social

Another excellent #Viewpoint! Thank you to our contributors @priyadevarajan.bsky.social, @rzappasodi.bsky.social, Novalia Pishesha, Jui-Hsia Weng, Kate Alexander, Yadira Soto-Feliciano, and @kedmiranit.bsky.social ✨

Latest in our #WomenInSTEM series from researchers discussing their science and the process of setting up a lab as an independent researcher, as well as the unique challenges they face as women scientists in their respective scientific environments: rupress.org/jem/article/...

👇🏻👇🏻

Asthma is a chronic disease characterized by acute, intermittent, recurrent episodes of airway inflammation. A decade of work developing the tools, techniques and collaborations needed to figure out how CD4+ T cells in the lungs propagate disease can be found here: www.biorxiv.org/content/10.1...

Nice!

Simply wonderful!

“If you look back at the data, 250 years ago, 40% of kids never made it to adulthood. Today, it’s 4%. The majority of that decrease is due to vaccines. Vaccines have saved more lives than any other type of medical intervention, including antibiotics... -Dr. Drew Weissman, Nobel Laureate.

Simply wonderful!

Thrilled to have our latest research @wehi-research.bsky.social published in @natimmunol.nature.com www.nature.com/articles/s41... This work was an outstanding partnership between talented PhD student Len Dalit (now postdoc, no 🦋) and bioinformatician @chinweetan.bsky.social Thread below...

I wish I could be there! Our amazing @annarudnitsky.bsky.social will give a talk on Friday — don’t miss it! www.nature.com/articles/s41...

The #IUIS2025 was way above my expectations! It was so great to meet old and new friends and to share our work. @iuis-online.bsky.social

It was mind blowing

Great keynote lecture by Ruslan Medzhitov on how the “educated” immune system of pet shop mice allows them to resist experimental allergic sensitisation. Thought provoking, as usual. #IUIS2025.

Some pics from the #RisingStars Day 2! Don't forget to share — which sessions have you liked the most so far? #ImmunologyWithoutBorders

Meet Dr @KedmiRanit, PI at Weizmann Institute. Her research reveals how immune cells coordinate to shape T cell responses. At #IUIS2025, she’ll present “A coordinated cellular network regulates intestinal tolerance.” 🔬🌍 https://loom.ly/CwagY2g#IUIS2025#RisingStars2025 #RoadtoVienna

Scientific research is at the heart of Israel’s success and has worldwide benefits. Our work will continue despite adversity, says Alon Chen https://go.nature.com/40wXMx6

Thanks for choosing me! See you there 🌟

Free/public access: rdcu.be/enZTa

'However, we now report that food-specific pTreg cells are exclusively induced by the recently identified RORγt APCs4–8 and not by cDCs. Instead, our data suggest that pTreg–cDC1 interactions in steady-state limit the expansion of food-specific CD8αβ T cells.' www.nature.com/articles/s41...

Incredible! Over the past 2 months, 5 independent manuscripts — from @TheColonnaLab, Dan Littman, @gardnerlabucsf.bsky.social and @chrysothemisbrown.bsky.social , and our own (now in @nature.com, www.nature.com/articles/s41...), reports that the dietary pTreg program is initiated by RORγt⁺ APCs. /1

Misinformation is winning not because it's true, but because it’s loud, emotional, and everywhere. It’s time for science to fight back. Aaron Mertz and I dissect the issue and offer solutions 👇 📖 www.nature.com/articles/s41... #SciComm @sinaiimmuno.bsky.social @aspeninstitute.bsky.social

Loved the episode! @itaiyanai.bsky.social In one of my many chats with ChatGPT, I asked about a protein—got: “Don’t you have something better to do in the holiday?”

A must read

#FirstLove #DendriticCellPower! Fernandes Rodrigues, Wu, Colonna &co show @CellCellPress that Rorgt DCs, not ILC3s, are fundamental to maintain gut Tregs, preventing Th2 cell expansion & #food #allergy! www.cell.com/cell/fulltex...

Cool germinal center acrobatics from Juhee Pae et al, check it out! www.nature.com/articles/s41...

@labwaggoner.bsky.social thank you for the spotlight! This has been a wonderful joint effort led by @cadwelllab.bsky.social in close collaboration @grahammunology.bsky.social, @belkaidlab.bsky.social, and P’ng Loke’s groups. First authors Ying-Han and Kim Zapdana led the way.

Very impressive paper by the Heeg and Goldrath labs using spatial transcriptomics to define CD8 Trm biology in the intestine in mice and humans. Congrats to @reinacampos.bsky.social and co-authors. #ImmunoSky

Looking for CD8 Tem and Tcm gene signatures for scRNAseq analysis Any recommendations?

Come and join us! www.linkedin.com/posts/weizma...

Excited to share our revised manuscript! We adapted new live imaging tools to track the same tissue resident macrophages for months in aging mice. We found a macrophage population that contributes to vascular health in young skin, but is lost as we age... www.biorxiv.org/content/10.1...

Only one week left to submit an abstract!

Congrats @cicacanesso.bsky.social. It is becoming clear that tolerance is generated by antigen-specific cellular network.

#Immunology by First release now @science.org Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection https://buff.ly/3DjNQ1e By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.

Staphylococcus aureus induces IL-10 which abrogates protective anti-staphylococcal antibody function through hyper-sialylation imprinting leading to vaccine failure @jclinical-invest.bsky.social www.jci.org/articles/vie... www.jci.org/articles/vie... www.genengnews.com/topics/infec...

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55

Adaptive immune regulation of innate immunity ✨ the paradigm has been innate immune regulation of adaptive immunity but the relationship is bidirectional. So much to discover and learn here. www.cell.com/immunity/ful...

Great review by Ranit Kedmi and Dan Littman on the biology of antigen presenting cell subsets in dictating T cell responses to commensal microbes and dietary antigens. Highly recommend #Immunosky 🧪

Wonderful to see the #immunology community growing here. The first starter pack is full (they cap at 150), so I created a second one. Let me know if you'd like to be added go.bsky.app/PY5tCas go.bsky.app/FmERUoD