'(...) these findings demonstrate the efficient generation of B cells from hPSCs and, in doing so, provide a system for further investigating the earliest stages of human B lymphopoiesis and a source of appropriately staged plasma cells for future therapeutic applications.' #Immunology #Preprint

I signed. In part, not despite of what has happened to Roger Innes (Indiana U, who was banned from his lab for complaining about government policies) but because of it. If we don't @standupforscience.net and support science-related policy, who will? Please consider signing too. All are invited.

L'État c'est moi

Um Estado como uma extensão do partido. Peculato. A Ana Paula Morte pode tudo. "Um membro do gabinete da ministra da Saúde presta assessoria jurídica informal ao Conselho de Jurisdição Nacional do PSD, cuja presidente é a própria Ana Paula Martins."

Goodbye GDP? 31 ways to replace the world’s favourite measure of economic health 🧪 www.nature.com/articles/d41...

Oof. At least now we know that you can't die of cringe.

TranscriptFormer: A generative cell atlas across 1.5 billion years of evolution www.science.org/doi/10.1126/... - this looks cool! 👀

A now annual Mother's Day tradition: celebrating this image and the poignant words of @rebeccasaxe.bsky.social about the complexity of identity and culture — and to the experience of motherhood. Thank you for it, Rebecca. www.smithsonianmag.com/science-natu...

The two pictures are 11 years apart. On 10 May 1933, the Nazi Party staged an ideological spectacle of the burning of 'un-German’ books. 2nd image: Auschwitz II-Birkenau, burning pits outside gas chamber and crematorium V, 1944. #Auschwitz warns us of where ideologies of hatred can lead people.

Excellent column from @kenanmalik.bsky.social on why Dawkins' musings about the "possible consciousness" of Claude/Claudia [!!] miss the point. observer.co.uk/news/technol...

Let's just take over all of the oil company infrastructure and turn it into housing. All of it.

sat down with a legend

Empty and Vapid. A good description of the acting CDC director too.

Meet the academics refusing to use generative AI Researchers say they have their reasons for avoiding AI tools — and they’re sick of arguing about it. www.nature.com/articles/d41... h/t @maartenp.bsky.social

Pause www.youtube.com/watch?v=z-gJ...

turns out when you legitimate a taste for bigotry people gravitate to the parties that serve it as an entree rather than as a garnish

Labour leaning further and further, and knowingly, into this particular trap

"Right now, there are more rules on opening a salon or a burrito shop than an AI startup" Very good piece here. So wild how that Jacobin piece echoed the same arguments used in a WaPo op-ed by *checks notes* PALANTIR EXECUTIVES

#ResistanceRoots Today in history, 1934: Longshoremen up and down the West Coast begin an 83-day strike, demanding better pay, shorter hours and union-controlled hiring halls. The sometimes violent strike ended on July 31 with significant labor victories that ended decades of employer control. /1

Dear Diary 'Brockman was forced this week to defend diary entries that appear to show he wanted to convert the non-profit into a commercial enterprise and get rich, as he revealed he owns a $30bn stake in the company. “It would be nice to be making the billions,” he wrote'

Completely unacceptable from the Board of Deputies. This nakedly partisan hypocrisy does not represent me or many other British Jews. www.theguardian.com/uk-news/2026...

This is the May cover of NN but it has already been debunked on biorxiv www.biorxiv.org/content/10.6... Such a clear statement about the ridiculous pace of publishing (not just NN).

Again, we don't have an Opposition Party, not even close; these people are a dangerous fucking joke, the lowest bar possible. We have a room full of people who are "colleagues" with fascists, who protect their capital at all cost & do the bare minimum to gaslight enough people to get reelected.

Trump is very deliberately & visibly killing the US wind power industry. Nobody even seems to be putting up a fight. As far as I can tell, the ACP -- the utterly fucking useless, spineless, compromised clean-energy trade association -- is responding with sternly worded letters.

Reminder: bioRxiv has Contradictory and Confirmatory Results categories to encourage studies of reproducibility. Yaniv Erlich had the previous record (hours) for demonstrating irreproducibility of a paper. Now apparently we have a negative time interval 😉

We are losing our best and brightest. Trump’s immigration policies will have an effect on immigrant scientists like Shirley Meng. She is stepping down as director of Energy Storage Research Alliance and will be relocating to Singapore. 🧪 www.science.org/content/arti...

Come visit us 🤓

The EMBO Lab Leadership for #Postdocs online course running 16–18 June still has places open. Three days on the people side of running research: - interpersonal skills - tools for your development - clearer communication Sign up here: www.embolableadership.org/course/embol... #EMBOLabLead

Registration for the Cell Biology and Cancer course at Institut Curie is now open! Explore how biological forms emerge across scales, from intracellular organization to tissues. 📅 November 16th-20th, 2026 (Paris) ⏳ Deadline: September 10th, 2026 🔗 training.institut-curie.org/cours/biolog...

Download our updated database of postdoc fellowships from different foundations and agencies. We identified 275 fellowships. For each entry, we provide description of the fellowship, focus, amount, deadline, eligibility, etc. Download this database here: research.jhu.edu/rdt/funding-...

É verdade que há um assalto a cada duas horas em Portugal. Mas essa verdade é uma mentira quando é dita depois da frase “com o aumento da insegurança no país” e omitindo que o número é 10% mais baixo do que em 2025.

For those keen!

Dozens of Israeli settlers stormed various areas of the West Bank, set cars on fire, and attacked Palestinians.

A complete accident, I'm sure. www.theguardian.com/technology/2...

Happy John Brown’s Birthday to all who celebrate.

Excited to share a new preprint from the lab led by @lukekoblan.bsky.social and William Colgan in which we describe our efforts to define a quantitative cell fate map of mouse embryogenesis! www.biorxiv.org/content/10.6...

They put one of yours in the hospital, you put out a statement about how disappointed you are. That’s the centrist way.

'Críticas às instituições internacionais, ao multilateralismo e à cooperação todos podemos fazer. Mas julgo que se impõe apresentar as alternativas e dizer como se age nestas circunstâncias. E, para o controlo de doenças infecciosas, efectivamente precisamos de cooperação internacional.'

The U.S. has spent billions to lose a war that enriches its oligarchs, impoverishes the citizenry, sabotages its alliances, and strengthens its enemies. Empires have risen and failed before, but to my knowledge no state has ever chosen to kill its own power. snyder.substack.com/p/on-superpo...

Empatia

'People have different constraints around their professional status and are “temperamentally different,” he noted. “You can’t expect everyone’s going to react politically in the same way.” Rather than think about obligations as scientists, he advised, think about what to do as a person.'

In other words, he lied.

In Wales as in Scotland, we rejected the odious Nigel Farage and his 3rd Reich replacement party, Reform. A relief, painful as it was to see the Welsh Labour Party biting the dust. Come on England, you're better than this. Help us to take this fascist down next time. For all our sakes. Never Reform

Maybe I just send them our project site: www.ru.nl/en/research/...

How do Endosomes dance? Looks like a waltz? Or maybe the more of a cèilidh? Cells expressing the PI(3)P probe imaged every 5s for ~15min. Currently preparing a really exciting paper about the regulation of endosomal PI(3)P homeostasis. Stay tuned!

www.cell.com/molecular-ce... check this beautiful paper

Spain just pulled off one of the fastest energy transformations in Europe. In 2000: ⚠️ 56% fossil ☀️🌬️ 2% solar + wind By 2026: ☀️🌬️ 44% solar + wind ⚠️ Just 17% fossil www.linkedin.com/posts/rentzh...

'Annette’s brush with death might seem like a one-off occurrence — an anomalous parade of errors and mishaps reserved for only the unluckiest among us. But that is not the case (...) in America, pregnancy is dangerous for Black women, regardless of privilege.'