Thiago Carvalho
@cyrilpedia.bsky.social
đ€ 5058
đ„ 6018
đ 10224
I've worked on all of science, from T cells to B cells.
https://fellowsherpa.com
'Still, Roche could be forgiven for starting to have second thoughts about jumping into the obesity space with both feet. Recent months have seen Novo kick off a major restructure in the wake of underwhelming data for its next-gen obesity portfolio.'
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Two years after Carmot buyout, whatâs next for Rocheâs expensive obesity pipeline?
Itâs been less than two years since Roche dove into the obesity space with its $2.7 billion acquisition of Carmot Therapeuticsâbut a lot has changed since then. | Itâs been less than two years since R...
https://www.fiercebiotech.com/biotech/two-years-after-carmot-buyout-whats-next-roches-expensive-obesity-pipeline
about 7 hours ago
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'Pacino says: âHe was the greatest director I ever worked with, in terms of working with (...) Directors came to see Sidney work. When he was on the cameras, how he operates, how he sets up a shot.â'
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Al Pacino on Dog Day Afternoon at 50: âIt plays more today than it even did thenâ
The 85-year-old actor talks the legacy of his stirring 1975 drama, his love of YouTube, fake death rumours and why he wonât discuss politics
https://www.theguardian.com/film/2025/sep/21/al-pacino-dog-day-afternoon-50th-anniversary
about 7 hours ago
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Dirk GĂŒtlin
about 7 hours ago
Structure transfer and consolidation in visual implicit learning đ§ đŠ đ§ đ€
elifesciences.org/articles/100...
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Structure transfer and consolidation in visual implicit learning
Sleep is essential for consolidating implicitly acquired perceptual knowledge that enables the knowledge transfer effect via newly learned structured information observed in prior studies of explicit ...
https://elifesciences.org/articles/100785
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âWeâre kicking around the idea of cutting costs to zero.â The reforms were being discussed in Number 10 and the Treasury before the Trump administration announced last week it would increase to $100,000 the application fee for an H-1B visa, which is relied on by US tech groups.'
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UK explores plan to drop visa fees for top global talent
PMâs team wants to make it easier to attract people from top universities as US moves in opposite direction
https://www.ft.com/content/3ba261c6-dfc4-43fb-b3a5-b715999fb731
about 7 hours ago
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'Se as propostas do Governo forem aprovadas, nĂŁo estaremos a resolver um problema de competitividade â porque ele nĂŁo estĂĄ nas leis laborais. Estaremos, sim, a fazer um favor aos sectores menos ambiciosos do tecido empresarial portuguĂȘs'
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O Governo quis passar de mansinho
A grande diferença entre o anteprojecto de lei da reforma laboral e outras grandes alteraçÔes ao direito do trabalho estĂĄ no actual contexto polĂtico.
https://www.publico.pt/2025/09/22/opiniao/opiniao/governo-quis-passar-mansinho-2147988?&_gl=1*xypcw4*_up*MQ..*_ga*MTQ3ODA5NTMzOS4xNzU2Nzc0OTIw*_ga_X1FCL58HX2*czE3NTg1MjU3ODMkbzY0JGcwJHQxNzU4NTI1NzgzJGo2MCRsMCRoMA.
about 7 hours ago
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BWJones
about 16 hours ago
A few years ago, I watched as two Finnish police officers stopped to help a woman on the street. One of the officers explained to me that Finland had decided to end homelessness. On top of that, they provide social services to the people they give homes too. Guess what? It's a good investment.
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Esquerda.Net
about 8 hours ago
âPor dentro do Chegaâ de Miguel Carvalho â uma leitura essencial
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âPor dentro do Chegaâ de Miguel Carvalho â uma leitura essencial
Este livro assusta tanto quanto provoca gargalhadas sonoras e Ă© uma leitura essencial para entender as direitas portuguesas, porque coloca boa parte da literatura acadĂ©mica e ensaĂstica mais recente em contexto (a bibliografia Ă© extensa e bem trabalhada com os testemunhos e investigação que realizou).
http://dlvr.it/TNCsX9
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Julio Pires đ§đ· #Lula2026
about 8 hours ago
QUE GIGANTE, RECIFE! â€ïžđ§đ·đđŸ
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Maria Lindqvist,PhD
about 8 hours ago
www.azolifesciences.com/news/2025012...
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Microglia Response Varies Between Male and Female Mice
A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, inside the brain, another "crew" of responders is busy clearing debris and re...
https://www.azolifesciences.com/news/20250122/Microglia-Response-Varies-Between-Male-and-Female-Mice.aspx
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'The Danish pharmaceutical industry, which is dominated by Novo Nordisk, accounted for 11 percent of the economyâs growth by the end of last year, according to a measure of the economy by the nationâs statistics office, up from 4 percent in 2019.'
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Novo Nordiskâs Woes Are Slimming Denmarkâs Economic Growth
https://www.nytimes.com/2025/09/22/business/novo-nordisk-denmark-economy.html
about 8 hours ago
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'(...) we conclude that the role of Dscam1 isoforms in canonical neuronal self-avoidance & S/NS discrimination is mediated by a small fraction of all isoforms (<1/10), whereas a separate role (...) likely in fitness and immunity, requires almost full isoform diversity'
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The modern expansion of Dscam1 isoform diversity in Drosophila is linked to fitness and immunity
The Drosophila Dscam1 gene generates tens of thousands of isoforms, yet only a small fraction supports neuronal functions. This study shows that fitness and immunity, rather than canonical neuronal ro...
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003383
about 8 hours ago
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Guilherme
about 8 hours ago
O misto de desdém e evangelismo nas intervençÔes de T r ” m p sobre K . r k percebem-se perfeitamente se, no meio da inundação de propaganda, nos lembrarmos que estå tudo a ser feito para que o Novo Estado lhe sobreviva. Não com aquele jovem, mas com outra qualquer figura, é indiferente
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Ruth Watson
about 8 hours ago
Israel is a rogue state.
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Mark A. Hanson
about 8 hours ago
Promising direction to recognise the reward of immigration at a time when so much toxic rhetoric is spewed in the opposite direction in
#UKPoli
. The question is can the Labour government actually do... something? For once? Forget their snafus. Let's see a positive policy established & celebrated.
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Dr Lindsey Fitzharris
about 8 hours ago
Please: if you have Indefinite Leave to Remain and are eligible for citizenship, apply now. In 2015, I went through a terrible divorce. I was on a marriage visa, and my ex reported me as illegally in the UK in order to get me deported. It was VERY scary. Your rights can disappear in a flash.
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Matthew Freeman
about 8 hours ago
Fingers crossed: this could make a big change in the perception and real substance of UK science and innovation (and all other talent...)
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Human Frontier Science Program
about 8 hours ago
đ§Ș From Alzheimerâs to motor proteins: research highlighted in the
#HFSPSummitJapan
HFSP-supported Japanese scientists uncovered a key mechanism in kinesin-1 movement with implications for neurodegenerative disease research. Read the science storyđ
bit.ly/4gzxHo1
#sts
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It's not hallucination, it's bullshit: 'In these, the writers complained that ChatGPT often conflated correlation & causation, failed to provide context (e.g., that soft actuators tend to be very slow), and tended to overhype results by overusing words like "groundbreaking" & "novel"'
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Science journalists find ChatGPT is bad at summarizing scientific papers
LLM âtended to sacrifice accuracy for simplicityâ when writing news briefs.
https://arstechnica.com/ai/2025/09/science-journalists-find-chatgpt-is-bad-at-summarizing-scientific-papers/
about 9 hours ago
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PLOS Biology
about 9 hours ago
During task performance, the brain must integrate information re goal-related objects with contextual details. This study shows that participants' performance on a
#SpatialNavigation
task is related to syncing of activity between
#hippocampus
&
#EntorhinalCortex
@plosbiology.org
đ§Ș
plos.io/3Vrw8id
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Adrian Liston
about 10 hours ago
My only regret is that we didn't go with the title "One buffer to rule them all, and in the darkness bind them", although "Squeaky clean staining" was a pretty good options too!
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about 9 hours ago
Las principales plataformas de comunicaciĂłn de masas del mundo se han rendido ante Trump y la maquinaria de la mentira
elpais.com/tecnologia/2...
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No creas a tus ojos: el saludo nazi de Musk y el mayor experimento de luz de gas de la historia
Las principales plataformas de comunicaciĂłn de masas del mundo se han rendido ante Trump y la maquinaria de la mentira
https://elpais.com/tecnologia/2025-01-22/no-creas-a-tus-ojos-el-saludo-nazi-de-musk-y-el-mayor-experimento-de-luz-de-gas-de-la-historia.html
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Thiago Carvalho
about 9 hours ago
Este libro es ante todo una mirada privilegiada al mundo de los tecnooligarcas y un retrato despiadado y certero de la hipocresĂa, insensatez y ligereza con la que se toman las grandes decisiones que condicionan la vida de miles de millones de personas
proassetspdlcom.cdnstatics2.com/usuaris/libr...
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Thiago Carvalho
Le Gorafi
3 days ago
Une universitĂ© amĂ©ricaine lance une enquĂȘte sur un professeur dâarchĂ©ologie suspectĂ© d'ĂȘtre un « antifa »
www.legorafi.fr/2025/09/19/u...
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Une universitĂ© amĂ©ricaine lance une enquĂȘte sur un professeur dâarchĂ©ologie suspectĂ© dâĂȘtre un « antifa »
LâuniversitĂ© amĂ©ricaine Marshall a annoncĂ© lancer une enquĂȘte approfondie concernant les activitĂ©s suspectes de lâun de ses enseignants, aujourdâhui dĂ©cĂ©dĂ©, une renommĂ©e du monde de lâarchĂ©ologie, le ...
https://www.legorafi.fr/2025/09/19/une-universite-americaine-lance-une-enquete-sur-un-professeur-darcheologie-accuse-davoir-ete-un-antifa/
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Tobi
4 days ago
If the government can celebrate scaring a critic off TV, the punchline writes itself â and itâs from 1933.
#JimmyKimmel
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Kevin the Librarian đȘđșđșđŠđšđŠđłïžâđ
about 10 hours ago
Oh
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Marnix Medema
about 9 hours ago
New preprint out by
#RobertKoetsier
, the first of his PhD project, on assessing the use of cross-species coexpression analysis to identify primary and secondary metabolic interactions in microbiomes:
www.biorxiv.org/content/10.1...
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Using cross-species co-expression to predict metabolic interactions in microbiomes
In microbial ecosystems, metabolic interactions are key determinants of speciesâ relative abundance and activity. Given the immense number of possible interactions in microbial communities, their expe...
https://www.biorxiv.org/content/10.1101/2025.09.11.675599v1
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Lisa OâCarroll
about 9 hours ago
Very good explainer/analysis in FT yesterday on whether Netanyahu will annex parts of West Bank.
www.ft.com/content/def5...
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Tiago Dias
about 9 hours ago
O Expresso teve acesso a casos em que o consulado de Islamabad recusou a emissĂŁo dos vistos a familiares de imigrantes, com base na avaliação de critĂ©rios jĂĄ validados pela AIMA, como a habitação ou os meios de subsistĂȘncia
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Embaixada de Portugal no PaquistĂŁo trava pedidos de reagrupamento familiar aprovados pela AIMA
O Expresso teve acesso a casos em que o consulado de Islamabad recusou a emissão dos vistos a familiares de imigrantes, com base na avaliação de critérios jå validados pela AIMA, como a habitação ou o...
https://expresso.pt/sociedade/migracoes/2025-09-22-embaixada-de-portugal-no-paquistao-trava-pedidos-de-reagrupamento-familiar-aprovados-pela-aima-e7891918
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Thiago Carvalho
European Research Council (ERC)
about 10 hours ago
đ§ȘRoman Jerala
@kemijski.bsky.social
developed a new method for modular protein design that allows controlled assembly and disassembly. The work is publicly available and could support advances in synthetic biology. đ
europa.eu/!4GrrNf
#Biochemistry
#Catalysis
#GeneEditing
@addgene.bsky.social
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Doug Dyer
2 days ago
Excellent but slightly sad to see this one out, my last contribution as a Postdoc to the Handel lab is in here, congrats to the main people on it!! More of evidence and mechanism of chemokine specificity!
www.jbc.org/article/S002...
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https://www.jbc.org/article/S0021-9258(25)02588-8/fulltext
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Merve Tepe, PhD
about 10 hours ago
Oh, wow, cool work
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Michael Baym
about 11 hours ago
When we build the greatest stereotype engine the world has ever seen we should not be surprised when it reproduces bias
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Patrick
about 10 hours ago
PhD and postdoc positions available in HPS at the University of Copenhagen. The project is âHuman Variables in Biodiversity Assessmentâ with Joeri Witteveen.
employment.ku.dk/phd/?show=16...
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PhD position in History and Philosophy of Science
https://employment.ku.dk/phd/?show=164906
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TRAstonDrs
about 11 hours ago
#Medskyđ§Ș
#IDsky
#Virosky
#immunosky
#publichealth
In a Q&A session
@statnews.com
, Prof Drew Weissman, the winner of the mRNA Nobel Prize, emphasised the vast body of literature that demonstrates the safety of
#COVID
đ
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Winner of mRNA Nobel Prize says ACIP memberâs claim that Covid vaccines persist is âabsolutely impossibleâ
In a Q&A with STAT, Nobel winner Drew Weissman addressed concerns raised about Covid shots at a recent meeting of federal vaccine advisers.
https://www.statnews.com/2025/09/20/drew-weissman-nobel-prize-mrna-covid-vaccines-rebuts-retsef-levi-claims/
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Alice Roberts
about 20 hours ago
Iâm watching and itâs astounding. We all knew something like this was going on - but the extent of it! While so many were suffering, dying, sunk into loneliness - a few were absolutely RAKING IT IN. The COVID health crisis was a very, very lucrative opportunity for some.
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bioRxiv Evolutionary Biology
about 20 hours ago
Evolution of sideways locomotion in crabs
https://www.biorxiv.org/content/10.1101/2025.09.20.677458v1
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Luke O'Neil
about 20 hours ago
Thinking today about this one by David Grossman on Studs Terkel, Father Coughlin, and "the long American history of convincing people that modern capitalism can finally be destroyed as soon as we get rid of (Jews, LGBT, immigrants, take your pick)"
www.welcometohellworld.com/im-not-sayin...
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I'm not saying monsters aren't real
Thatâs what happens when you try to build socialism without socialism
https://www.welcometohellworld.com/im-not-saying-monsters-arent-real/
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Jon Cooper
1 day ago
I donât know whether I should laugh or cry, but this really pisses me off.
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Thiago Carvalho
Juan S. Bonifacino
1 day ago
Big thanks to Amelia Glazier and
@jcellsci.bsky.social
for including me in âFirst Personsâ through the decades â 100â years of notable scientists in Journal of Cell Science
journals.biologists.com/jcs/article/...
Happy to be in such great company!
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âFirst Personsâ through the decades â 100â years of notable scientists in Journal of Cell Science
Summary: JCS highlights the lives and careers of 10 notable scientists from around the world who published first author papers in our journal over the last 100â years.
https://journals.biologists.com/jcs/article/138/17/jcs264351/369118/First-Persons-through-the-decades-100-years-of
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Dr. Karen Weaver
about 20 hours ago
And the faculty and staff who have received minimal raises in since before Covid đČđł "$50 million will be added to the Hokiesâ athletic department budget by the end of the month.", per
@espn.com
clutchpoints.com/ncaa-footbal...
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Virginia Tech infusing $50 million into athletic department budget
Virginia Tech injects $50 million into athletics while coaching search heats up, signaling big changes for the Hokies.
https://clutchpoints.com/ncaa-football/virginia-tech-football-news-hokies-infusing-50-million-athletic-department-budget
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Safaa Dib
about 20 hours ago
Agora reparo como a Ășltima temporada do HACKS foi totalmente presciente em relação Ă linha que separa os artistas das empresas que sĂł querem lucro e audiĂȘncias (e servir ditadores).
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Anders Sejr Hansen
about 22 hours ago
Asking BlueSky for help: For a review, I am trying to accurately credit the first paper that measured pairwise 3D distances between 2 pieces of DNA on the same chromosome (or cosmid). Is Trask 1989 the first? I know of earlier single-locus papers (1982).
www.sciencedirect.com/science/arti...
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O CĂŁo Danado
3 days ago
Candidata democrata
@katmabu.bsky.social
do Illinois a ser agredida violentamente por agentes do ICE num protesto pacĂfico. Se ao menos os Democratas Americanos tivessem o espĂrito combativo da Kat.
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đparaverđ©đĄđ„
1 day ago
Censored by Bezos
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Manuel Barbosa
2 days ago
NĂŁo passa dum Governo de neoliberais, com apoio da extrema-direita parlamentar, absolutamente incapaz de resolver os problemas das pessoas, mas duma enorme eficiĂȘncia no aumento das desigualdades e das injustiças sociais. A Social-democracia no PSD definitivamente morta e enterrada!
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T. Ryan Gregory đšđŠ
about 20 hours ago
apnews.com/article/leba...
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Israeli drone strike kills 5, including 3 children, in southern Lebanon
Lebanonâs Health Ministry says an Israeli drone strike in southern Lebanon has killed five people, including three children. The attack took place on Sunday.
https://apnews.com/article/lebanon-israel-airstrike-hezbollah-676b98efa8998e80d01d058565e5a73a?utm_source=twitter&utm_medium=share&s=09
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Coach Finstock
about 24 hours ago
This is truly insane. The definition of "disappearing people"
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Catarina Martins
5 days ago
Nos incĂȘndios, o governo portuguĂȘs foi irresponsĂĄvel e atrasou o combate. Mas o mecanismo europeu tambĂ©m nĂŁo respondeu a tempo. Passaram 5 longos dias desde o pedido de ajuda atĂ© chegarem os primeiros aviĂ”es.
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vargas
5 days ago
Vai ser difĂcil o PSD produzir outra ministra tĂŁo empenhada em gozar com a nossa cara
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