bioRxiv Bioinfo
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📤 4714
📥 0
📝 9194
CellFluxV2: An Image Generative Foundation Model for Virtual Cell Modeling
https://www.biorxiv.org/content/10.64898/2026.01.19.696785v1
13 minutes ago
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Benchmarking Next-Generation Sequencing Platforms: A Comprehensive Comparison Of Single-Cell RNA-Seq from Ultima UG 100 vs. Illumina NovaSeq X Plus
https://www.biorxiv.org/content/10.64898/2026.01.16.699571v1
about 1 hour ago
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1
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Medea: An omics AI agent for therapeutic discovery
https://www.biorxiv.org/content/10.64898/2026.01.16.696667v1
about 1 hour ago
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eTRex Reveals Oncogenic Transcriptional Regulatory Programs Across Human Cancers
https://www.biorxiv.org/content/10.64898/2026.01.16.699950v1
about 5 hours ago
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Dynamics-aware Evolutionary Profiling Uncouples Structural Rigidity from Functional Motion to Enable Enhanced Variant Interpretation
https://www.biorxiv.org/content/10.64898/2026.01.16.699945v1
about 5 hours ago
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High-PepBinder: A pLM-Guided Latent Diffusion Framework for Affinity-Aware Target-Specific Peptide Design
https://www.biorxiv.org/content/10.64898/2026.01.12.698988v1
1 day ago
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dgiLIT: A Method for Prioritization and AI Curation of Drug-Gene Interactions
https://www.biorxiv.org/content/10.64898/2026.01.16.699733v1
1 day ago
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SE3Bind: SE(3)-equivariant model for antibody-antigen binding affinity prediction
https://www.biorxiv.org/content/10.64898/2026.01.17.700115v1
2 days ago
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2
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Structural alphabets approach performance of structural alignment in remote homology detection
https://www.biorxiv.org/content/10.64898/2026.01.16.699908v1
3 days ago
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1
AFsample3: Generating and selecting multipleconformational states with Alphafold3
https://www.biorxiv.org/content/10.64898/2026.01.16.699904v1
3 days ago
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2
1
NetCrafter: Ontology-derived gene network modeling and interpretation
https://www.biorxiv.org/content/10.64898/2026.01.16.699831v1
4 days ago
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2
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Mitigating Bias in Spatial Transcriptomic Pipelines via Human Feedback
https://www.biorxiv.org/content/10.64898/2026.01.15.699786v1
4 days ago
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1
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TcrDesign: De novo design of epitope specific full-length T cell receptors
https://www.biorxiv.org/content/10.64898/2026.01.15.699824v1
4 days ago
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GARD: Genomic Data based Drug Repurposing in Head and Neck Cancer with Large Language Model Validation
https://www.biorxiv.org/content/10.64898/2026.01.15.699561v1
4 days ago
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PathDiffusion: modeling protein folding pathway using evolution-guided diffusion
https://www.biorxiv.org/content/10.64898/2026.01.16.699856v1
4 days ago
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1
1
TomoSegNet: Augmented membrane segmentation for cryo-electron tomography by simulating the cellular context
https://www.biorxiv.org/content/10.64898/2026.01.15.699326v1
4 days ago
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1
1
Leveraging Unified Sequence-Structure Representations for Enhanced Protein Stability Prediction
https://www.biorxiv.org/content/10.64898/2026.01.15.699740v1
4 days ago
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1
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mtDNA-Network: a web tool to explore mitochondrial variant profiles in complex diseases
https://www.biorxiv.org/content/10.64898/2026.01.15.699732v1
4 days ago
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Signal Strength Aware Latent Spaces Reveal Molecularly Distinct Substructures within Human Kidney Tissue
https://www.biorxiv.org/content/10.64898/2026.01.15.699686v1
4 days ago
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AtlasMap: enabling low-cost, map-style exploration of million-cell single-cell atlases
https://www.biorxiv.org/content/10.64898/2026.01.14.699595v1
5 days ago
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1
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RAREsim2: Flexible simulation of rare variant genetic data using real haplotypes
https://www.biorxiv.org/content/10.64898/2026.01.14.694480v1
5 days ago
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Label-free detection of individual virus-infected cells using deep learning
https://www.biorxiv.org/content/10.64898/2026.01.15.699499v1
5 days ago
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Enhancing volumetric microscopy with blind computational correction of spatially variant aberrations using neural field representation
https://www.biorxiv.org/content/10.64898/2026.01.15.699665v1
5 days ago
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DeepSpaceDB 2.0: an interactive spatial transcriptomics database for large-scale Xenium data exploration
https://www.biorxiv.org/content/10.64898/2026.01.15.699623v1
5 days ago
0
3
1
Extending Conformational Ensemble Prediction to Multidomain Proteins and Protein Complex
https://www.biorxiv.org/content/10.64898/2026.01.14.699584v1
5 days ago
0
1
1
When CycloneSEQ meets Oxford Nanopore Technologies: a performance comparison of contemporary nanopore DNA sequencing platforms
https://www.biorxiv.org/content/10.64898/2026.01.14.699587v1
5 days ago
2
2
2
Predicting Clinical Phenotypes by Growth Curve Modeling of Transcriptomic Signatures during Disease Progression
https://www.biorxiv.org/content/10.64898/2026.01.13.699292v1
5 days ago
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1
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Empirical-Bayes and Bayesian Hierarchical Modelling forMissingness and Differential Expression in Proteomics
https://www.biorxiv.org/content/10.64898/2026.01.15.699650v1
5 days ago
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1
1
Constructing the ensemble of representative structures for a protein via neural-surrogate-guided MSA recombination
https://www.biorxiv.org/content/10.64898/2026.01.14.699462v1
5 days ago
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Spatial Regression of Morphology-Protein Coupling in Tumour Proteomics
https://www.biorxiv.org/content/10.64898/2026.01.14.699547v1
5 days ago
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Enabling automatic generation of protein-ligand complex datasets with atomistic detail
https://www.biorxiv.org/content/10.64898/2026.01.15.699426v1
5 days ago
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1
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Real-paired single-cell/bulk RNA-seq benchmark and a practical protocol for accurate cell-type deconvolution in human BAL samples
https://www.biorxiv.org/content/10.64898/2026.01.14.699304v1
6 days ago
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1
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On the rise of AI technologies for virtual screening
https://www.biorxiv.org/content/10.64898/2026.01.14.699425v1
6 days ago
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Automating the Construction of Contextualized Biomedical Knowledge Graphs for Scientific Inference
https://www.biorxiv.org/content/10.64898/2026.01.14.699420v1
6 days ago
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A supervised ontology-aware cell annotation method forsingle-cell transcriptomic data
https://www.biorxiv.org/content/10.64898/2026.01.13.699356v1
6 days ago
0
3
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Brain Region-Specific Oligodendrocyte States Highlight Mitochondrial Gene Upregulation and Loss of Canonical Identity Signatures in Alzheimers Disease
https://www.biorxiv.org/content/10.64898/2026.01.14.699226v1
6 days ago
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Unifying phylogenetic traversal and deep learning to guide tree exploration
https://www.biorxiv.org/content/10.64898/2026.01.14.699358v1
6 days ago
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1
1
Fusion gene discovery in single cells from high throughput long read single cell transcriptomes
https://www.biorxiv.org/content/10.64898/2026.01.13.699333v1
6 days ago
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1
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Hypatia: a set of quantitative methods for profiling isoform across cell populations
https://www.biorxiv.org/content/10.64898/2026.01.13.699341v1
6 days ago
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Quantitative Full-length transcriptome analysis by nanopore sequencing with Error-Aware UMI mapping
https://www.biorxiv.org/content/10.64898/2026.01.14.699429v1
6 days ago
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1
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Outlier Detection in Single-Cell Transcriptomics Reveals Disease-Enriched Cytotoxic Immune Populations
https://www.biorxiv.org/content/10.64898/2026.01.12.699092v1
6 days ago
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1
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3D reconstruction of spatial transcriptomics with spatial pattern enhanced graph convolutional neural network
https://www.biorxiv.org/content/10.64898/2026.01.13.699328v1
6 days ago
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3
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System-wide extraction of cis-regulatory rules from sequence-to-function models in human neural development
https://www.biorxiv.org/content/10.64898/2026.01.14.699402v1
6 days ago
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Advancing Protein Design via Multi-Agent Reinforcement Learning with Pareto-Based Collaborative Optimization
https://www.biorxiv.org/content/10.64898/2026.01.13.699365v1
6 days ago
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Integrated Multi-omics Analysis Identifies Molecular Signatures of Regular Physical Activity in Human Peripheral Blood
https://www.biorxiv.org/content/10.64898/2026.01.13.699221v1
6 days ago
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LoopBin, a VaDE-based neural network for chromatin loop classification
https://www.biorxiv.org/content/10.64898/2026.01.13.699359v1
6 days ago
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1
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Hybrid TF-IDF and SBERT Feature Engineering with SMOTE-Tomek Resampling for Enhanced Software Requirements Classification
https://www.biorxiv.org/content/10.64898/2026.01.13.699413v1
6 days ago
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1
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Reference-free microsatellite instability detection from tumor sequencing using intrasample variability modeling
https://www.biorxiv.org/content/10.64898/2026.01.13.699258v1
6 days ago
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1
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Benchmarking computational decontamination of ambient RNA
https://www.biorxiv.org/content/10.64898/2026.01.13.699237v1
6 days ago
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SoftHybrid: A Hybrid Imputation Algorithm Optimised for Single-Cell Proteomics Data
https://www.biorxiv.org/content/10.64898/2026.01.13.699212v1
6 days ago
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0
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