Landscape of 8q24.3-Encoded microRNAs and Their Prognostic Impact in Ovarian Cancer https://www.biorxiv.org/content/10.64898/2026.03.06.710032v1

MSstatsResponse: Semi-parametric statistical model enhances detection of drug-protein interactions in chemoproteomics experiments https://www.biorxiv.org/content/10.64898/2026.03.09.710598v1

The Genomic Legacy of Ancient Polyploidy in Crop Domestication https://www.biorxiv.org/content/10.64898/2026.03.09.710542v1

FishMamba-1: A Linear-Complexity Foundation Model for Deciphering Polyploid Cyprinid Genomes https://www.biorxiv.org/content/10.64898/2026.03.09.710409v1

Cell DiffErential Expression by Pooling (CellDEEP) highlights issues in differential gene expression in scRNA-seq https://www.biorxiv.org/content/10.64898/2026.03.09.710522v1

BICEP: an extension to indels and copy number variants for rare variant prioritisation in pedigree analysis https://www.biorxiv.org/content/10.64898/2026.03.09.710467v1

Rational in silico discovery and serological validation of Trypanosoma cruzi-specific B-cell epitopes for high-precision Chagas disease diagnosis https://www.biorxiv.org/content/10.64898/2026.03.09.710567v1

Making Biorisk Measurable: A Bayesian Framework for Laboratory Risk Management https://www.biorxiv.org/content/10.64898/2026.03.09.710076v1

Pairing Data Independent Acquisition and High-Resolution Full Scan for Fast Urinary Tract Infection Diagnosis https://www.biorxiv.org/content/10.64898/2026.03.09.710302v1

CESAR: High-Sensitivity Detection of Copy Number Variations in ctDNA Using Segmentation and Anchor Recalibration https://www.biorxiv.org/content/10.64898/2026.03.09.710442v1

MESSI: Multimodal Experiments with SyStematic Interrogation using nextflow https://www.biorxiv.org/content/10.64898/2026.03.09.710452v1

Unsupervised identification of low-frequency antigen-specific TCRs using distance-based anomaly scoring https://www.biorxiv.org/content/10.64898/2026.03.09.709174v1

Modularity, ecology, and theoretical evolution of the ribozyme body plan https://www.biorxiv.org/content/10.64898/2026.03.07.710320v1

HAETAE: A highly accurate and efficient epigenome transformer for tissue-specific histone modification prediction https://www.biorxiv.org/content/10.64898/2026.03.09.708388v1

Beyond Binding Affinity: The Kinetic-Compatibility Hypothesis for Nipah Virus Neutralization https://www.biorxiv.org/content/10.64898/2026.03.08.710350v1

Automated extraction and optimization of protein purification protocols using multi-agent large language models https://www.biorxiv.org/content/10.64898/2026.03.03.709341v1

PhosSight: a Unified Deep Learning Framework Boosting and Accelerating Phosphoproteome Identification to Enable Biological Discoveries https://www.biorxiv.org/content/10.64898/2026.03.08.708781v1

Phosphorylation of a tumor-derived ASXL2 epitope remodels 1 peptide-HLA binding affinity and interaction dynamics https://www.biorxiv.org/content/10.64898/2026.03.08.710418v1

Developing SCL2205 : A Protein Sequence-based Spatial Modelling Dataset for the Protein Language Model Frontier https://www.biorxiv.org/content/10.64898/2026.03.08.710388v1

Intrinsic dataset features drive mutational effect prediction by protein language models https://www.biorxiv.org/content/10.64898/2026.03.08.710389v1

Hunting for microsatellite instability in long-read data with Owl https://www.biorxiv.org/content/10.64898/2026.03.08.708905v1

Inferring large networks with matrix factorisation to capture non-linear dependencies among genes using sparse single-cell profiles https://www.biorxiv.org/content/10.64898/2026.03.08.710347v1

FAMUS: A Few-Shot Learning Framework for Large-Scale Protein Annotation https://www.biorxiv.org/content/10.64898/2026.03.08.710366v1

Improving Causal Gene Identification Using Large Language Models https://www.biorxiv.org/content/10.64898/2026.03.08.710344v1

DIA-NN EasyFilter workflow for the fast and user-friendly critical assessment and visualization of DIA-NN proteomics analysis outcome https://www.biorxiv.org/content/10.64898/2026.03.07.710308v1

NanoVI: a Bayesian variational inference Nextflow pipelinefor species-level taxonomic classification from full-length16S rRNA Nanopore reads https://www.biorxiv.org/content/10.64898/2026.03.07.710315v1

Exploring per-base quality scores as a surrogate marker of cell-free DNA fragmentome https://www.biorxiv.org/content/10.64898/2026.03.08.710357v1

From General-Purpose to Disease-Specific Features: Aligning LLM Embeddings on a Disease-Specific Biomedical Knowledge Graph for Drug Repurposing https://www.biorxiv.org/content/10.64898/2026.03.07.707871v1

Counting strands in outer membrane beta-barrels https://www.biorxiv.org/content/10.64898/2026.03.07.710327v1

NeuroNarrator: A Generalist EEG-to-Text Foundation Model for Clinical Interpretation via Spectro-Spatial Grounding and Temporal State-Space Reasoning https://www.biorxiv.org/content/10.64898/2026.03.07.707799v1

Neurotox: Deep learning decodes conserved hallmarks of neurotoxicity across venomous species https://www.biorxiv.org/content/10.64898/2026.03.07.710323v1

InversePep: Diffusion-Driven Structure-Based Inverse Folding for Functional Peptides https://www.biorxiv.org/content/10.64898/2026.03.06.710241v1

MOZAIC: Compound Growth via In Silico Reactions and Global Optimization using Conformational Space Annealing https://www.biorxiv.org/content/10.64898/2026.03.07.710272v1

SpatioCAD: Context-aware graph diffusion model for pinpointing spatially variable genes in heterogeneous tissues https://www.biorxiv.org/content/10.64898/2026.03.06.708087v1

In silico analysis of the human titin protein (Immunoglobulin-like, fibronectin type III, and Protein kinase domains) as a potential forensic marker for postmortem interval (PMI) estimation https://www.biorxiv.org/content/10.64898/2026.03.06.710245v1

Measuring Amorphous Motion: Application of Optical Flow to Three-Dimensional Fluorescence Microscopy Images https://www.biorxiv.org/content/10.64898/2026.03.06.710169v1

Automatic Generation of Model Sequences for Complex Regions in Assembly Graphs https://www.biorxiv.org/content/10.64898/2026.03.06.710180v1

AQuA2-Cloud: a web platform for fluorescence bioimaging activity analysis https://www.biorxiv.org/content/10.64898/2026.03.06.709938v1

STAR Suite: Integrating transcriptomics through AI software engineering in the NIH MorPhiC consortium https://www.biorxiv.org/content/10.64898/2026.03.09.710580v1

Computed atlas of the human GPCR-G protein signaling complexes https://www.biorxiv.org/content/10.64898/2026.03.07.710286v1

Assessing the impact of parental linear gene normalization on the performance of statistical models for circular RNA differential expression analysis https://www.biorxiv.org/content/10.64898/2026.03.06.710045v1

CAPRINI-M: An AI-curated Cardiac-Specific Atlas of Protein Interactions in Mice https://www.biorxiv.org/content/10.64898/2026.03.06.710104v1

Classification with Missing Data - A NIFty Pipeline for Single-Cell Proteomics https://www.biorxiv.org/content/10.64898/2026.03.06.710179v1

Benchmarking 80 binary phenotypes from the openSNP dataset using deep learning algorithms and polygenic risk score tools https://www.biorxiv.org/content/10.64898/2026.03.06.710126v1

A Novel Glycoproteomics Platform for High-Throughput Identification of Disease-Associated Glycoforms https://www.biorxiv.org/content/10.64898/2026.03.06.708406v1

Defining mutational signatures of lung cancer-associated carcinogens through in vitro exposure of human airway epithelial cells https://www.biorxiv.org/content/10.64898/2026.03.05.707509v1

Quantum Hamiltonian Learning using Time-Resolved Measurement Data and its Application to Gene Regulatory Network Inference https://www.biorxiv.org/content/10.64898/2026.03.05.709897v1

Fractal: Towards FAIR bioimage analysis at scale with OME-Zarr-native workflows https://www.biorxiv.org/content/10.64898/2026.03.05.709921v1

Benchmarking tissue- and cell type-of-origin deconvolution in cell-free transcriptomics https://www.biorxiv.org/content/10.64898/2026.03.05.709833v1

MapMyCells: High-performance mapping of unlabeled cell-by-gene data to reference brain taxonomies https://www.biorxiv.org/content/10.64898/2026.03.06.710160v1