ALS as an autoimmune disease? Jason Gale at @bloomberg.com talks with LJI Prof. Alessandro Sette (@settelab.bsky.social) about groundbreaking new findings: www.bloomberg.com/news/article... [PAYWALL] #immunology #health #ALS #AutoimmuneDisese #Autoimmunity

We've never known exactly what might cause ALS. A new @nature.com paper, led by LJI Professor Alessandro Sette (@settelab.bsky.social), shows how how inflammatory T cells target the brain and trigger cell death: www.lji.org/news-events/... #health #medicine #disease #ALS #immunology

Scientists have found that patients with ALS have autoimmune responses, a finding that could reshape how researchers view the devastating neurologic disorder. My latest for @statnews.com on a new study in @nature.com from @settelab.bsky.social @lji.org www.statnews.com/2025/10/01/a...

Exciting "Live from the Lab" webinar coming up TOMORROW, Oct. 1, at 12 PM Pacific! Join Dr. Sonia Sharma, Dr. Amparo Martínez Pérez and Laura Hinojosa for a fascinating discussion on sex-based differences, #immunology, #endometriosis, hormonal contraceptives + more bit.ly/42PtR4o #Health #Medicine

Check out our latest special collection on Skin Immunity: www.mucosalimmunology.org/mucimm-skin-...

Violante's project at @lji.org seeks to unlock prostate cancer immunotherapies - take a peek by yourself @cancerresearchinst.bsky.social

"Immunometabolism, the intersection of cellular metabolism and immune function, has revolutionized our understanding of T cell biology." LJI experts share key discoveries from the growing field of immunometabolism! 👇 #Tcells #Cd1Mr12025

Behind every experiment is a story of curiosity, resilience, and hope!☀️ LJI scientists share the personal side of their research — how their own backgrounds and their loved ones motivate them to make discoveries in #immunology: youtu.be/EKLowprj26U?... #science #health #medicine #disease #SanDiego

KPBS #Science reporter Thomas Fudge talks with LJI scientists about a fascinating new study — Learn how "ghost" viruses in our DNA can come back to haunt us: www.kpbs.org/news/science... #virology #SanDiego #health #medicine

Exciting faculty news! Immunologist Benjamin Schmiedel, Ph.D., has been appointed to a tenure-track Assistant Professor position at LJI: bit.ly/46lL3AK #SanDiego #LaJolla #Immunology #ImmuneSystem #Science #Health

Another great new @cp-cellreports.bsky.social paper from LJI's Saphire Lab — Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation: bit.ly/4lTts7K #COVID19 #virology #StructuralBiology #CellularBiology #Health #Medicine

A stunning first look at the viruses inside us by the Saphire lab

From cancer to virology—learn how early career scientists at LJI are becoming leaders in #immunology through the Tullie and Rickey Families SPARK Awards for Innovations in Immunology: youtu.be/a4k9ZKi_HfQ?... #health #medicine #biology #STEM #SanDiego

Nominate a deserving colleague for an AAI Career Award and celebrate their outstanding contributions to immunology research, service, and mentorship. Recognize excellence at all career levels, from seasoned professionals to new investigators. Deadline is Sept 10. www.aai.org/Awards/Career.

Morgan gave such a fascinating talk at a @cshlaboratory.bsky.social meeting last year we had to invite him for an encore. Please join us @lji.org! via @mskcancercenter.bsky.social

Just published — LJI researchers reveal the first 3D structure of a protein from a human endogenous retrovirus. Your cells make this protein by expressing ancient viral DNA. And it's unlike anything seen before... www.lji.org/news-events/... #health #medicine #SanDiego #biology #virology #science

Data access coming up soon... stay tuned!

Big news in #immunology: ImmGenMaps partners with BioTuring to share immune cell insights bit.ly/4mX3MrO "This will make it possible for other scientists to cross-reference genes and cell types in their research." @immgen.bsky.social @reinacampos.bsky.social‬ #SanDiego #Science #Health #Medicine

Congratulations to LJI Professor, President & CEO Erica Ollmann Saphire, Ph.D., MBA! Dr. Saphire has been named the 2025 Mainly Mozart #SanDiego Genius Award Honoree in recognition of her groundbreaking #immunology research and leadership in the scientific community! 🔬 www.mainlymozart.org/genius

#SigmaXiAwards @lji.org Congratulations to our 2025 Procter Prize recipient, La Jolla Institute for Immunology's Alessandro Sette. Read More: ow.ly/qFn350WHSR7 Awards: ow.ly/pTxi50WHSR6 IFoRE: ow.ly/jubN50WHSR8

New in Protein Science 🔬 LJI Prof. Bjoern Peters (@bjoernpeters.bsky.social) and colleagues analyze large-scale T-cell receptor sequence data to uncover determinants of MHC-I versus MHC-II recognition — onlinelibrary.wiley.com/doi/10.1002/... #ImmuneSystem #Tcells #Immunology #Health #Medicine

Brand New #FITdb (fitdb.lji.org) tool now LIVE! Do you have a list of genes? You can use "Compare My Geneset" to test if these are overly-represented among functional regulators of T cells across more than 60 conditions! @lji.org supported and developed by Kevin Kim, Xinjian Cen and Harrison Ma.

Ahh Friday, the perfect time to post something fun and not a fraught topic in any way...

LJI Assistant Professor Miguel Reina-Campos, Ph.D. (@reinacampos.bsky.social) leads fascinating #ImmuneCell research in his lab. Now he's being recognized by @aai.org on a national stage! Congrats, Dr. Reina-Campos! www.youtube.com/watch?v=ib7O... #SanDiego #Science #STEM #health #medicine

Congratulations to LJI Professor Alessandro Sette, Dr.Biol.Sci. (@settelab.bsky.social)! The Procter Prize from Sigma Xi honors Dr. Sette's impact as an immune system researcher and a science communicator! bit.ly/3Jhqe0s #Immunology #science #health #medicine #SanDiego #STEM

Fascinating #ImmuneSystem discovery from @tulanemedicine.bsky.social! Apparently it's time to learn from worms! 🪱🪱🪱

We are honored to part of a proposed panel for SXSW (‪@sxsw.com‬) titled, “The Sex Factor: How Biological Bias Hurts Everyone.” The panel will delve into: 1) How outdated norms decelerate #health innovation AND...🧵

Congratulations to former LJI trainee Dr. Camila Coelho (now at the Icahn School of Medicine at Mount Sinai)! 🎉 Dr. Coelho has been named a "Rising Star" by Union of Immunological Societies — an award for early-stage researchers who are revolutionizing the field! bit.ly/4mGyF3H #health #medicine

LJI scientists recently made a big advance in the quest for a "universal" coronavirus vaccine! 🦠 Learn how a deep dive into T cell epitopes led to this new vaccine research pipeline: bit.ly/47ajwTV @cellpress.bsky.social #Viruses #ImmuneSystem #Tcells #SanDiego #health #medicine #science #STEM

An interesting look at how LJI scientists are harnessing #AI tools to improve vaccine development: bit.ly/4lqvbBn This research, led by LJI Research Assistant Professor Alba Grifoni, Ph.D. (@albagrifoni.bsky.social), offers a new pipeline for addressing emerging viruses with pandemic potential.

New in @science.org — LJI scientists explore the importance of sex-based differences in the immune system: bit.ly/45G2882 “LJI scientists have uncovered a whole new body of information about how the immune systems of men and women are very different." - Dr. Erica Ollmann Saphire #health #medicine

New in @science.org: LJI experts explore how sex-based differences shape the immune system—and our disease risks: www.science.org/doi/10.1126/... #medicine #health #cancer #AutoimmuneDisease #ChronicDisease #CancerImmunotherapy #SanDiego #science

Dr. Alba Grifoni (@albagrifoni.bsky.social) and her team share new research that could help us fight many viruses at once—and stop emerging diseases in their tracks! bit.ly/45EYs6C #virology #immunology #Tcells #health #medicine #STEM #SanDiego

Just out on @cp-cell.bsky.social! Focusing on Conserved T-cell Epitope Regions (CTERs) increases the ability of T cells to recognize Coronaviruses of pandemic concern. This strategy is broadly applicable to other viral families @tertuapn.bsky.social @lji.org www.sciencedirect.com/science/arti...

Interesting #COVID19 insights from LJI scientists and experts at @hipcproject.bsky.social:

Congratulations to the talented group of LJI summer interns who presented their work on Friday! 🔬😀 These interns got hands-on experience with immune system research this summer — and gained great career experience! #SanDiego #STEM #Immunology

Cheers for the LJI scientists and staff who walked, spun, ran, and rode in the Curebound #Cancer Challenge, held yesterday at @ucsandiego.bsky.social! This awesome team braved the heat and even exceeded their fundraising goal for #CancerResearch! Way to go! 🎉 #SanDiego #LaJolla #health

Cockroach allergies are surprisingly common, especially in kids! Learn more about cockroach allergies -- and the fascinating science of #allergy shots: bit.ly/3Uq3Hkp #biology #health #immunology #ImmuneSystem #SanDiego

Each year, around 2.6M Americans receive #allergy immunotherapies, also called “allergy shots.” LJI scientists are investigating how these therapies target the very immune cells that drive dangerous allergic reactions. bit.ly/3Uq3Hkp @settelab.bsky.social #AllergyShots #Health #Medicine #SanDiego

In our new study we show local B-cell immunity and durable memory following live-attenuated influenza intranasal vaccination of humans. We utilized minimally invasive swabbing of human upper airway, following seasonal intramuscular or nasal (FluMist) flu vaccinations www.biorxiv.org/content/10.1...

We are a network of 8 big members: @lji.org @columbiamed.bsky.social @yalemedicine.bsky.social MIT @seattlechildrens.bsky.social @stanfordimmunology.bsky.social Icahn Mt. Sinai @benaroyaresearch.bsky.social You can upload our #free data at immunespace.org Image from 2020. 🧪 #ImmuneSky

A new LJI study offers the first-ever map of which parts of #Chikungunya virus trigger the strongest response from the body’s T cells bit.ly/45NmDjQ The study also offers clues for to why infection can trigger chronic, severe joint pain. #ChronicDisease #Virology #Health #Medicine

💥 Couldn’t be more stoked our study identifying a completely new CMV virion surface complex involved in cell entry is now published at Nature Micro 🦠 H/T @paramyxologist.bsky.social + Lauren Henderson, Erica Ollmann Saphire Chris Benedict @natmicrobiol.nature.com www.nature.com/articles/s41...

Our project spans 8+ institutions, with human cohorts studied with multiplex transcriptional, #cytokine, and #proteomic assays; multiparameter #phenotyping of leukocyte subsets + many computational methods. Get our #data for your own investigations. #ImmuneSky #IDsky immunespace.org

LJI and Pitt scientists uncover how a common herpes virus outsmarts the immune system: bit.ly/4ey4Y1U “We found a missing puzzle piece that represents one possible reason why immunization efforts against CMV have been unsuccessful.” #virology #medicine #StructuralBiology #health #SanDiego

Welcome, LJI summer interns! We hope you learn, grow, and make strong connections this summer as you explore #STEM careers and more at La Jolla Institute for Immunology! 🔬🎉

We are so thrilled to welcome UC San Diego’s PATHS program interns and high school interns to LJI! Our white coat ceremony marks the beginning of an amazing summer of learning, mentorship, and career development! #SanDiego #Science #Health #Medicine #STEM

There's a lot we need to learn about #Parkinsons disease— LJI Prof. Alessandro Sette (@settelab.bsky.social) and colleagues show how detection of potentially harmful T cells could lead to earlier Parkinson's diagnosis—and open the door to therapeutic interventions: www.lji.org/news-events/...

A new timeline for Parkinson’s disease? LJI's @settelab.bsky.social and colleagues discover that T cells may allow for early detection of Parkinson's cases—years before motor symptoms development www.lji.org/news-events/... #Parkinsons #ImmuneSystem #Tcells #Aging #Neuroscience

Huge kudos to a former LJI trainee! Dr. Coelho is leading critical #immunology research on the international stage!