Always excited to partecipate to the Iedb workshop #iedbuw2025 @iedb.bsky.social

In our latest vaccine immunology study we tested whether it is possible to simultaneously prime multiple classes of broadly neutralizing antibodies (bnAbs) against HIV using a combination of germline-targeting (GT) immunogens. www.science.org/doi/10.1126/... @scienceimmuno.bsky.social @lji.org

An interesting look at how LJI scientists are harnessing #AI tools to improve vaccine development: bit.ly/4lqvbBn This research, led by LJI Research Assistant Professor Alba Grifoni, Ph.D. (@albagrifoni.bsky.social), offers a new pipeline for addressing emerging viruses with pandemic potential.

LJI scientists recently made a big advance in the quest for a "universal" coronavirus vaccine! 🦠 Learn how a deep dive into T cell epitopes led to this new vaccine research pipeline: bit.ly/47ajwTV @cellpress.bsky.social #Viruses #ImmuneSystem #Tcells #SanDiego #health #medicine #science #STEM

Dr. Alba Grifoni (@albagrifoni.bsky.social) and her team share new research that could help us fight many viruses at once—and stop emerging diseases in their tracks! bit.ly/45EYs6C #virology #immunology #Tcells #health #medicine #STEM #SanDiego

Just out on @cp-cell.bsky.social! Focusing on Conserved T-cell Epitope Regions (CTERs) increases the ability of T cells to recognize Coronaviruses of pandemic concern. This strategy is broadly applicable to other viral families @tertuapn.bsky.social @lji.org www.sciencedirect.com/science/arti...

A new LJI study offers the first-ever map of which parts of #Chikungunya virus trigger the strongest response from the body’s T cells bit.ly/45NmDjQ The study also offers clues for to why infection can trigger chronic, severe joint pain. #ChronicDisease #Virology #Health #Medicine

Each year, around 2.6M Americans receive #allergy immunotherapies, also called “allergy shots.” LJI scientists are investigating how these therapies target the very immune cells that drive dangerous allergic reactions. bit.ly/3Uq3Hkp @settelab.bsky.social #AllergyShots #Health #Medicine #SanDiego

After 30+ years of HIV vaccine clinical trials, this is the first time that neutralizing antibodies against an HIV clinical isolate has been generated in vaccinated people. * "Tier 2" neutralizing antibodies, induced consistently. www.science.org/doi/10.1126/... www.science.org/doi/10.1126/...

For our final #PathogenOfTheWeek post, we've imagined "Virus X." This pathogen represents a future threat to global health. LJI scientists know that the next pandemic threat may come from a newly emerged or evolved pathogen—one we've never faced. 1/2 🧵 #GlobalHealth #immunology

One of our obsessions in the Crotty lab is to better understand B-cell immunology in the context of vaccines. Rare B cells can have antibody specificities particularly important for protection against some diseases. In our most recent paper… @cp-immunity.bsky.social www.cell.com/immunity/ful...

#PathogenOfTheWeek: SARS-CoV-2, the virus that causes COVID-19, is probably the most recognizable pathogen of our time. LJI scientists have been at the forefront of #COVID19 vaccine research, and they've made critical discoveries. 1/2 🧵 #virology #InfectiousDisease #SARSCoV2 #pandemic

JCI Insight - Frequency of dengue virus–specific T cells is related to infection outcome in endemic settings insight.jci.org/articles/vie...

Great article from @nature.com on how the COVID-19 pandemic has advanced our understanding of the immune system — featuring important work led by LJI Prof. Alessandro Sette and colleagues: www.nature.com/articles/d41... #COVID19 #SARSCoV2 #Vaccines #Tcells #Antibodies

How can we stop pathogens with #pandemic potential? LJI researchers share new "roadmap" for harnessing T cell cross-reactivity to combat viruses pubmed.ncbi.nlm.nih.gov/39819529/ @settelab.bsky.social @albagrifoni.bsky.social #Immunology #Virology #Tcells #ImmuneSystem

LJI Prof. Alessandro Sette on the role of T cells in combatting flu viruses: “Our research in general has shown that T-cells play an important role not in preventing infection but in making the disease less severe,” Sette said. www.kpbs.org/news/science... #Virology #InfectiousDisease #BirdFlu

Hello T cell enthusiasts! Ever tried to combine an AIM and ICS assay? If not, here is the protocol for you!