Out Now! Navigating the promise and pitfalls of artificial intelligence #MicroSky

Out Now! Prediction of eukaryotic cellular complexity in Asgard archaea using structural modelling #MicroSky

Our March issue is out, featuring... 🤖the promise and pitfalls of AI 🙅gasdermins thwarting bacterial pathogens 🌽Trichoderma fungi for sustainable agriculture 🐛mechanisms of insect-bacterium mutualism 🫘microbiome impacts on chronic kidney disease ...and more 👇 www.nature.com/nmicrobiol/v...

Read our review about the "Diversity, ecology, cell biology and evolution of the Asgard archaea" in @natrevmicro.nature.com here: www.nature.com/articles/s41... By @kassipan.bsky.social @stephkoe.bsky.social @micropat.bsky.social & @gerbenz.bsky.social

🧵 1/10 New paper out in @natmicrobiol.nature.com from my postdoc at @mib-wur.bsky.social! 🎉 How eukaryote-like was the archaeal ancestor of eukaryotes? Sequence searches alone can't tell us — so we used protein structure prediction to look deeper. 🧬 www.nature.com/articles/s41...

Out Now! Retraction Note: Metabolic remodelling produces fumarate via the aspartate–argininosuccinate shunt in macrophages as an antiviral defence #MicroSky

Join @berasymbionts.bsky.social , @tatsuyanobori.bsky.social and us for a postdoc on the remarkable developmental biology of symbiosis! Applications are due March 25th 🪲🦠 @johninnescentre.bsky.social @thesainsburylab.bsky.social

Out Now! Phenogenomics reveals the ecology and evolution of Trichoderma fungi for sustainable agriculture #MicroSky

For Pokémon’s 30th anniversary, Nature spoke to scientists from around the world about how their work has been shaped by playing Pokémon games, watching animated TV series and films and trading cards in school playgrounds. 🧪

Out Now! Skin androgens affect virulence of Staphylococcus aureus #MicroSky

Out Now! Skin androgens regulate Staphylococcus aureus pathogenicity via quorum sensing #MicroSky

Out Now! Tryptophanase disruption promotes insect–bacterium mutualism #MicroSky

Grateful to Jacob Smith for interviewing me for @natmicrobiol.nature.com @natureportfolio.nature.com, alongside brilliant microbiologists from around the world. The field is evolving fast and entering a digital era of discovery! www.nature.com/articles/s41...

Out Now! Gut bacteria ammonia production restores acetylcholine neurotransmission and bowel motility #MicroSky

#NatMicroPicks A microbial signature of health! 🦠⚕️ A large meta-analysis highlights the importance of previously unknown and uncultured gut bacteria in maintaining human health #MicroSky www.cell.com/cell-host-mi...

#NatMicroPicks Fungi host invasion! 🍄🌱 Mechanism of fungal turgor generation, that aids mechanical host penetration by fungus could present new targets for disease control in plants #MicroSky www.science.org/doi/10.1126/...

#NatMicroPicks Mpox transmission caught in action! 🐿️🦠🐒 A wild squirrel-to-mangabey interspecies transmission highlights the risk to the population that hunts these animals for food #MicroSky www.nature.com/articles/s41...

#NatMicroPicks A broad respiratory vaccine! 🦠🫁💉 An intranasal liposomal vaccine combining TLR4 and TLR7/8 ligands with ovalbumin produced broad and durable respiratory protection in mice #MicroSky www.science.org/doi/10.1126/...

#NatMicroPicks Aerobic archaeal-eukaryotic ancestor? 🦠🫁 The ancestor of eukaryotes may have combined hydrogen metabolism with aerobic respiration, shaping early cellular complexity. #MicroSky www.nature.com/articles/s41...

#NatMicroPicks C. diff vaccine! 🦠💉 A protective mucosal vaccine formulation that provides sterilizing immunity to clear C. difficile from the host. #MicroSky www.nature.com/articles/s41...

Ein Paper aus meiner Postdoc-Zeit kam heute in @natmicrobiol.nature.com raus! Wir haben untersucht, wie sich Darmbakterien von Menschen mit HIV auf die Immunreaktion und Infektionen von Mäusen (ohne HIV) auswirken, um perspektivisch neue Behandlungen zu entwickeln: www.nature.com/articles/s41... 🧪

Review: Gasdermins against intracellular bacterial pathogens @natmicrobiol.nature.com www.nature.com/articles/s41...

🎆Very excited to share our perspective piece calling for higher standards in reports on microbial detection in cancers! It was great to put this together with some of the leaders in the field including @stevensalzberg.bsky.social @rafalab.bsky.social Barry Marshall and Eske Willerslev: rdcu.be/e4IaU

Out Now! Gut microbial ammonia enhances colonic acetylcholine levels to regulate intestinal motility #MicroSky

Out Now! Gasdermins against intracellular bacterial pathogens #MicroSky

Out Now! How taurine keeps asymptomatic malaria infections in check #MicroSky

Out Now! Conserved CD4+ T cell staphylococcal and streptococcal epitopes enable broad-acting vaccines in mice #MicroSky

Out Now! Longitudinal plasma metabolomics reveals a role for taurine in asymptomatic malaria and seasonal persistence #MicroSky

Out Now! Candida auris vacuolar calcium pump mediates fluconazole efflux and resistance evolution #MicroSky

Out Now! Human immunodeficiency virus-associated gut microbiome impacts systemic immunodeficiency and susceptibility to opportunistic gut infection #MicroSky

🚨 New paper out today in Nature Microbiology! During my postdoc we explored how the gut microbiome of people living with HIV impacts immune function and susceptibility to opportunistic infections. 🧵 1/10

What’s holding back clinical use of phage therapy in the UK? Our workshop last year brought together international experts, biotech and regulators to find out Meeting Report out now in Nature Microbiology with our take on the challenges and opportunities facing the UK phage therapy sector

Out Now! Realizing phage therapy in the UK #MicroSky

I am seeking a postdoc to join my group at UCLA -- ideally the candidate would have some experience in either population genetics or microbes/microbiome (computational background needed). We have a range of projects and are happy to tailer to your interests. Please dm/email me if interested.

Out Now! Targeted innate immune inhibition therapy compared with antibiotics for recurrent acute cystitis: a randomized, open-label phase 2 trial #MicroSky

ICYMI Out Now! Addendum: ESKAPE pathogens rapidly develop resistance against antibiotics in development in vitro #MicroSky

ICYMI Out Now! Host factors dictate gut microbiome alterations in chronic kidney disease more strongly than kidney function #MicroSky

ICYMI: Out now! Out Now! mRNA vaccination overcomes haemozoin-mediated impairment of whole-parasite malaria vaccines in mice

#NatMicroPicks FMT for cancers in clinic! 💩🦠🦀⚕️ Three different clinical trials report activity of faecal microbiota transplant against cancer #MicroSky #CancerSky www.nature.com/articles/s41... www.nature.com/articles/s41...

#NatMicroPicks It matters where cancer-associated bacteria are! 🦀💊 The spatial localization of bacteria associated with tumors dictates opposite immune outcomes - driving metastasis or triggering antitumour neutrophil activity #MicroSky www.cell.com/cell/fulltex...

#NatMicroPicks Enhancing anti-fungals! 💊🍄 A natural‑product butyrolactol A restores caspofungin activity against intrinsically resistant Cryptococcus neoformans and multidrug‑resistant Candida auris #MicroSy www.cell.com/cell/fulltex...

#NatMicroPicks Host enzyme, fungal targets! 🍄🦠 Intestinal epithelial cells secrete METTL9, a host methyltransferase that directly modifies fungal proteins to block essential zinc acquisition #MicroSky www.cell.com/cell-host-mi...