Niranjan Nagarajan
@niranjantw.bsky.social
๐ค 74
๐ฅ 35
๐ 12
Computational Biologist and Microbiome Scientist at the National University of Singapore
pinned post!
Published finally! Our study describing the use of metagenomics for AMR/pathogen surveillance in food-centres island-wide in Singapore is out in npj Antimicrobial & Resistance:
nature.com/articles/s44...
loading . . .
Citywide metagenomic surveillance of food centres reveals local microbial signatures and antibiotic resistance gene enrichment - npj Antimicrobials and Resistance
npj Antimicrobials and Resistance - Citywide metagenomic surveillance of food centres reveals local microbial signatures and antibiotic resistance gene enrichment
https://nature.com/articles/s44259-025-00132-0
2 months ago
0
0
1
Published finally! Our study describing the use of metagenomics for AMR/pathogen surveillance in food-centres island-wide in Singapore is out in npj Antimicrobial & Resistance:
nature.com/articles/s44...
loading . . .
Citywide metagenomic surveillance of food centres reveals local microbial signatures and antibiotic resistance gene enrichment - npj Antimicrobials and Resistance
npj Antimicrobials and Resistance - Citywide metagenomic surveillance of food centres reveals local microbial signatures and antibiotic resistance gene enrichment
https://nature.com/articles/s44259-025-00132-0
2 months ago
0
0
1
Skin
#metatranscriptomics
could be transformational in a way not seen in gut/oral studies as 1) Defined spatial sampling can provide in vivo relevant insights 2) Microbial mRNA is dominant, but human mRNA is also readily detected and quantified
www.nature.com/articles/s41...
loading . . .
Skin metatranscriptomics reveals a landscape of variation in microbial activity and gene expression across the human body - Nature Biotechnology
Skin metagenomic and metatranscriptomic analysis shows divergence between microbial abundance and activity.
https://www.nature.com/articles/s41587-025-02797-4
2 months ago
0
2
0
Our study developing a skin metatranscriptomics protocol is now out in
@natbiotech.nature.com
! We finally have the ability to study microbial activity on skin and identify key functional genes playing a role in diseases. Amazing team of Chia Minghao and Amanda Ng ๐
nature.com/articles/s41...
2 months ago
1
13
6
reposted by
Niranjan Nagarajan
Nature Biotechnology
2 months ago
Skin metatranscriptomics reveals a landscape of variation in microbial activity and gene expression across the human body -
@niranjantw.bsky.social
@astar-gis.bsky.social
go.nature.com/4fVg95j
loading . . .
Skin metatranscriptomics reveals a landscape of variation in microbial activity and gene expression across the human body - Nature Biotechnology
Skin metagenomic and metatranscriptomic analysis shows divergence between microbial abundance and activity.
https://go.nature.com/4fVg95j
1
11
8
Our work on direct
@nanoporetech.com
sequencing of non-canonical bases in now out in
@natcomms.nature.com
! Read all about it here:
nature.com/articles/s41...
Great collab with Chew and Hirao lab
x.com/NiranjanTW/s...
loading . . .
Direct high-throughput deconvolution of non-canonical bases via nanopore sequencing and bootstrapped learning - Nature Communications
Perez, Kimoto, Rajakumar and colleagues present a fast and accurate DNA sequencing method that reads canonical and non-canonical bases using AI and nanopore technology. The approach enables an expande...
https://nature.com/articles/s41467-025-62347-z
3 months ago
0
6
5
reposted by
Niranjan Nagarajan
A*STAR Genome Institute of Singapore (A*STAR GIS)
6 months ago
Find out how our researchersโAssociate Director
@niranjantw.bsky.social
, GIS Innovation Fellow Chayaporn Suphavilai and Dr Karrie Koโdiscovered a new variation of ๐๐ข๐ฏ๐ฅ๐ช๐ฅ๐ข ๐ข๐ถ๐ณ๐ช๐ด (๐.๐ข๐ถ๐ณ๐ช๐ด)โ๐ฐ๐น๐ฎ๐ฑ๐ฒ ๐ฉ๐โa drug-resistant yeast that kept infectious disease experts on high alert worldwide. Full story below๐:
loading . . .
https://research.a-star.edu.sg/articles/highlights/mapping-an-evolving-fungal-foe/
0
2
1
reposted by
Niranjan Nagarajan
A*STAR Genome Institute of Singapore (A*STAR GIS)
5 months ago
Studying low-biomass environments in microbiome research? The struggle is real when it comes to contamination! Even the tiniest sprinkle of external microbes can throw off your results, making traditional methods a no-go. Details in link below:
@niranjantw.bsky.social
www.nature.com/articles/s41...
loading . . .
Guidelines for preventing and reporting contamination in low-biomass microbiome studies - Nature Microbiology
In this Consensus Statement, the authors outline strategies for processing, analysing and interpreting low-biomass microbiome samples, and provide recommendations to minimize contaminants.
https://www.nature.com/articles/s41564-025-02035-2
0
1
1
reposted by
Niranjan Nagarajan
Chengchen Li (Cherry)
6 months ago
Which skin microbiome type do you have ๐ค Check out our exciting work from the Asian Skin Microbiome Program offering new insights of skin microbiome population heterogeneity๐
#skinmicrobiome
#microbiomescience
add a skeleton here at some point
1
3
1
Super thrilled to share our labor of love from the Asian Skin Microbiome Program! We collected >3,500 skin samples, built metagenomic libraries w/ >70 billion reads and >10TB of data to study heterogeneity of the skin microbiome in the general population (200 adults, 18 sites)
t.co/ZylbJMpvpw
loading . . .
Large-scale skin metagenomics reveals extensive prevalence, coordination, and functional adaptation of skin microbiome dermotypes across body sites
The human skin microbiome is increasingly recognized to influence skin health, immune function and disease susceptibility. However, large-scale, multi-site metagenomic studies in the general populatio...
https://www.biorxiv.org/content/10.1101/2025.04.24.650393v1
6 months ago
1
12
15
A bit late to joining the Bluesky party, but it's great to see all the amazing scientists who are on this platform! Looking forward to connecting with all of you here (on twitter as @niranjantw ... so keeping the handle consistent).
7 months ago
2
5
2
you reached the end!!
feeds!
log in