Nature Reviews Endocrinology (@natrevendo.nature.com)

The autonomic nervous system in the regulation of glucose and lipid metabolism Nature Reviews Endocrinology, Published online: 05 January 2026; doi:10.1038/s41574-025-01221-wChronic disturbances in autonomic regulation are increasingly recognized as contributors to metabolic diseases such as obesity and type 2 diabetes mellitus. In this Review, Wangler and colleagues discuss bidirectional communication between the autonomic nervous system and peripheral tissues in the coordination of glucose and lipid metabolism as well as emerging therapies targeting autonomic pathways that could improve metabolic health. https://www.nature.com/articles/s41574-025-01221-w?utm_source=bluesky&utm_medium=social&utm_campaign=nrendo