New online! Progress and challenges in sporadic late-onset cerebellar ataxias

New online! Myotonic dystrophy type 1: clinical diversity, molecular insights and therapeutic perspectives

Gut-derived metabolites drive Th17 cell pathogenicity in multiple sclerosis www.sciencedirect.com/science/arti...

Clearing truncated tau protein restores neuronal function and prevents microglia activation in tauopathy mice www.sciencedirect.com/science/arti...

Mutations of schizophrenia risk gene SETD1A dysregulate synaptic function in human neurons www.nature.com/articles/s41...

The 2024 revisions of the McDonald criteria for diagnosis of multiple sclerosis were published yesterday. In our Clinical Outlook article, Marcello Moccia, Olga Ciccarelli and Alan Thompson consider practical implementation of the new criteria. www.nature.com/articles/s41...

In the 2024 McDonald criteria for diagnosis of multiple sclerosis, dissemination in time is no longer required. In our Comment article, Xavier Montalban, Agustín Pappolla and Georgina Arrambide discuss the reasons and the implications. www.nature.com/articles/s41...

The 2024 McDonald criteria for multiple sclerosis allow diagnosis without clinical symptoms. In our Comment, Andrew Solomon and John Brodersen consider the risk of overdiagnosis that comes with these changes. www.nature.com/articles/s41...

What do the 2024 McDonald criteria mean for the multiple sclerosis prodrome? Helen Tremlett discusses this in our Comment, highlighting the opportunity it presents to better understand the prodromal phase. www.nature.com/articles/s41...

ICYMI: New online! Non-invasive brain stimulation: current and future applications in neurology

Psychedelic neuroplasticity of cortical neurons lacking 5-HT2A receptors www.nature.com/articles/s41...

Spatial transcriptomic analysis reveals lack of response to PD-1 blockade in recurrent glioblastoma link.springer.com/article/10.1...

New online! Non-invasive brain stimulation: current and future applications in neurology

ICYMI: New online! Health disparities in neurology

Plasma P-Tau217 to Identify Preclinical AD jamanetwork.com/journals/jam...

Revised Diagnostic Criteria for Vascular Cognitive Impairment and Dementia jamanetwork.com/journals/jam...

Join an expert-led Q&A session on Sept 22 with Nature Reviews editors to explore lifelong learning in clinical science. Learn how review articles support doctors at every career stage. Register now: go.nature.com/4phth98 #medsky

Cerebellar pathology contributes to neurodevelopmental deficits in spinal muscular atrophy academic.oup.com/brain/advanc...

ICYMI: New online! A role for lithium in Alzheimer disease

ICYMI: New online! Health disparities in neurology

ICYMI: New online! The changing landscape of primary autoimmune neuropathies

The 150th American Academy of Neurology Annual Meeting (#ANA2025) begins this weekend, and our Senior Editor Heather Wood will be attending. For a taster of what's to come, see her interview with ANA President M. Elizabeth Ross bit.ly/428A5fo

ICYMI: New online! ANA2025 marks important milestones for the ANA and NINDS

ICYMI: New online! Neuronal ceroid lipofuscinosis: underlying mechanisms and emerging therapeutic targets

New online! Health disparities in neurology

Ambient Air Pollution and the Severity of Alzheimer Disease Neuropathology jamanetwork.com/journals/jam...

ICYMI: New online! From adaptive deep brain stimulation to adaptive circuit targeting

ICYMI: New online! A role for lithium in Alzheimer disease

New online! A role for lithium in Alzheimer disease

Real-world effectiveness of autologous haematopoietic stem cell transplantation for multiple sclerosis in the UK jnnp.bmj.com/content/earl...

A blood-based DNA damage signature in patients with Parkinson’s disease is associated with disease progression www.nature.com/articles/s43...

ICYMI: New online! The changing landscape of primary autoimmune neuropathies

ICYMI: New online! ANA2025 marks important milestones for the ANA and NINDS

ICYMI: New online! Neuronal ceroid lipofuscinosis: underlying mechanisms and emerging therapeutic targets

New online! The changing landscape of primary autoimmune neuropathies

Rewiring of cortical glucose metabolism fuels human brain cancer growth www.nature.com/articles/s41...

Dynamic fibroblast–immune interactions shape recovery after brain injury www.nature.com/articles/s41...

PICALM Alzheimer’s risk allele causes aberrant lipid droplets in microglia www.nature.com/articles/s41...

Single-cell transcriptomic and genomic changes in the ageing human brain www.nature.com/articles/s41...

New online! ANA2025 marks important milestones for the ANA and NINDS

New online! Neuronal ceroid lipofuscinosis: underlying mechanisms and emerging therapeutic targets

ICYMI: New online! From adaptive deep brain stimulation to adaptive circuit targeting

In #DeepBrainStimulation the two major developments across the last decade have been 1. Adaptive DBS and 2. Connectomic DBS In a @natrevneurol.nature.com article with @julianneumann.bsky.social, we ask: Could the two be united into a common framework? www.nature.com/articles/s41... A 🧵

New online! From adaptive deep brain stimulation to adaptive circuit targeting

Our featured article for September is a Review by Michael Maes and colleagues on the dysregulation of neuroimmune, metabolic and oxidative stress pathways in major depressive disorder - click on this link to access the PDF for free: rdcu.be/eDFVH

Our September issue, which includes articles on sex differences in frontotemporal dementia, amyloid-lowering immunotherapies for Alzheimer disease and dementia research in low and middle-income countries, is now live! bit.ly/4mG3Ufr

Targeting phagocytosis for amyloid-β clearance: implications of morphology remodeling and microglia activation probed by bifunctional chimaeras www.nature.com/articles/s41...

Microglia regulate neuronal activity via structural remodeling of astrocytes www.sciencedirect.com/science/arti...

ICYMI: New online! Targeting sodium channels — challenges for acute pain and the leap to chronic pain

Axonal injury is a targetable driver of glioblastoma progression www.nature.com/articles/s41...