Ambient mass spectrometry imaging enables spatial metabolomics of optimal cutting temperature compound (OCT)-embedded tumors https://www.biorxiv.org/content/10.1101/2025.11.05.686836v1

Iron addicted colorectal cancers exploit Heme-Complex II axis to resist oxidative cell death https://www.biorxiv.org/content/10.1101/2025.11.05.686813v1

Identification of Therapeutic Gene Targets in Triple-Negative Breast Cancer: A Hybrid Approach Integrating Semidefinite Programming, Boolean Simulation, and Druggability Analysis https://www.biorxiv.org/content/10.1101/2025.11.05.686831v1

A structural and regulatory framework for Atg9-containing vesicle formation and their Atg1-dependent remodelling during autophagy initiation https://www.biorxiv.org/content/10.1101/2025.11.06.685569v1

Generalizing Drift Diffusion Models with a State-Dependent Framework https://www.biorxiv.org/content/10.1101/2025.11.05.686838v1

Two cortical mechanisms of audiovisual processing in the human brain https://www.biorxiv.org/content/10.1101/2025.11.05.686819v1

Cargo-directed assembly of nonviral nucleocapsid with controlled size https://www.biorxiv.org/content/10.1101/2025.11.06.684264v1

When Animals Turn Inside Out: The Eversion of Bloodworms https://www.biorxiv.org/content/10.1101/2025.11.05.686822v1

Hybrid untargeted and targeted RNA sequencing facilitates genotype-phenotype associations at single-cell resolution https://www.biorxiv.org/content/10.1101/2025.11.06.686971v1

Scalable and systematic hierarchical virus taxonomy with vConTACT3 https://www.biorxiv.org/content/10.1101/2025.11.06.686974v1

HyperBind2: Multi-Shot Learning Enables Progressive Improvement in Computational Antibody Discovery https://www.biorxiv.org/content/10.1101/2025.11.06.687005v1

Culmorin inhibits detoxification of the mycotoxin deoxynivalenol by plant UDP-glucosyltransferases https://www.biorxiv.org/content/10.1101/2025.11.06.686973v1

RNA-Focused DNA-Encoded Library Construction, Screening, and Integration of Docking Identify Bioactive Ligands of Pathogenic r(G4C2)exp RNA https://www.biorxiv.org/content/10.1101/2025.11.06.686979v1

Environmental Contributions to Proton Sharing in Protein Low-Barrier Hydrogen Bonds https://www.biorxiv.org/content/10.1101/2025.11.05.686872v1

Base editing and nanoparticle transfection of airway cell types essential for treatment of cystic fibrosis https://www.biorxiv.org/content/10.1101/2025.11.06.687048v1

CARP Protects Against Doxorubicin-induced Cardiotoxicity through NRF1-driven Mitochondrial Homeostasis https://www.biorxiv.org/content/10.1101/2025.11.06.683842v1

Genetic and Epigenetic Factors Influencing Methamphetamine Addiction and Aggressive Behavior among Iraqi Adult men https://www.biorxiv.org/content/10.1101/2025.11.05.686833v1

Oxidative stress triggers RNAPII arrest through PARylation and DNA damage https://www.biorxiv.org/content/10.1101/2025.11.06.686939v1

mRNA 3' UTRs direct microRNA degradation to participate in imprinted gene networks and regulate growth https://www.biorxiv.org/content/10.1101/2025.11.06.686990v1

Multi-omic characterization of the sow colostrum and milk microbiome and proteome https://www.biorxiv.org/content/10.1101/2025.11.05.686862v1

Proton stress adaptation in acidophilic sulfate-reducing bacteria: insights from Acididesulfobacillus acetoxydans for acid mine drainage bioremediation https://www.biorxiv.org/content/10.1101/2025.11.06.686915v1

Mosquito NF-κB-mediated innate immunity exerts arbovirus-specific antiviral effects at multiple stages of the viral life cycle https://www.biorxiv.org/content/10.1101/2025.11.06.687020v1

Increased mutation rates and diversity are dominant features of Geobacter multiheme cytochromes https://www.biorxiv.org/content/10.1101/2025.11.06.686851v1

Proteomic characterization of extracellular vesicles from 12 commensal bacterial species https://www.biorxiv.org/content/10.1101/2025.11.06.686325v1

Naturally occurring CodY variants alter ligand binding, DNA target affinity, and virulence in Clostridioides difficile https://www.biorxiv.org/content/10.1101/2025.11.06.687015v1

A phage-derived reconfigurable effector associated with an actinobacterial contractile nanomachine tailors bacterial responses to competition https://www.biorxiv.org/content/10.1101/2025.11.06.686954v1

Surveillance of migratory shorebirds and seabirds in 2024 in Australia reveals incursions of a diversity of low pathogenicity avian influenza viruses, but not high pathogenicity avian influenza H5N1 https://www.biorxiv.org/content/10.1101/2025.11.06.687052v1

Miniature inverted-repeat transposable elements mobilize diverse antibiotic resistance genes in Enterobacteriaceae https://www.biorxiv.org/content/10.1101/2025.11.05.686661v1

Symbiont diversity and light-organ morphology in Sepiola affinis https://www.biorxiv.org/content/10.1101/2025.11.06.686942v1

Human Papillomavirus Infection Blunts STING Signaling and Alters Downstream Response https://www.biorxiv.org/content/10.1101/2025.11.06.686957v1

Streptococcus pneumoniae fratricide-induced cell lysis does not require the type IV competence pilus. https://www.biorxiv.org/content/10.1101/2025.11.06.685197v1

De novo Cyclic Peptides Allow Visualisation of the Monomeric and Functional Amyloid Conformations of the Kinase RIPK3 https://www.biorxiv.org/content/10.1101/2025.11.05.686663v1

Hypoxia-induced mitoROS triggers M1 linear ubiquitin chains and activates NF-κB signaling https://www.biorxiv.org/content/10.1101/2025.11.06.686916v1

A Quantitative Review of Biodiversity Trends during the Great Ordovician Biodiversification Event https://www.biorxiv.org/content/10.1101/2025.11.05.686803v1

Massively parallel evolution reveals a biophysical scaling law between cell size and internal cell density https://www.biorxiv.org/content/10.1101/2025.11.05.686806v1

Deep Learning Enables Automated Segmentation and Quantification of Ultrastructure from Transmission Electron Microscopy Images https://www.biorxiv.org/content/10.1101/2025.11.05.686793v1

Strain-dependent variation in maternal care and early behavioral development in laboratory rats https://www.biorxiv.org/content/10.1101/2025.11.05.686817v1

The eukaryotic horizontal gene transfer dataset a compendium https://www.biorxiv.org/content/10.1101/2025.11.05.686818v1

Evaluating Field Trial Designs for Genetically Modified Mosquito Interventions: An In-Silico Simulation Approach https://www.biorxiv.org/content/10.1101/2025.11.05.686816v1

Lateral plate mesoderm directs human amnion and ventral skin organoid formation https://www.biorxiv.org/content/10.1101/2025.11.05.685987v1

Unraveling yeast diversity in food fermentation using ITS1-2 amplicon-based metabarcoding https://www.biorxiv.org/content/10.1101/2025.11.05.686804v1

Atomistic TCR-ligand interactions instruct memory T-cell differentiation https://www.biorxiv.org/content/10.1101/2025.11.05.686789v1

Persistent Activation of Monocytes/Macrophages and Cell Senescence in SIV-Infected Macaques on ART https://www.biorxiv.org/content/10.1101/2025.11.05.686810v1

Maternal care modulates chloride cotransporter development during inhibitory circuit maturation in the piriform cortex https://www.biorxiv.org/content/10.1101/2025.11.05.686805v1

Coupling mathematical modeling with a novel human intestinal stem cell system to understand feedback regulation during planar cell polarity https://www.biorxiv.org/content/10.1101/2025.11.05.686808v1

Predator-prey scaling laws support a suspension-feeding lifestyle in Cambrian lobopodians https://www.biorxiv.org/content/10.1101/2025.11.05.686786v1

Integrated Proteomic and Epigenomic Analysis Reveals IGF2 as a Vulnerability in PRC2-Deficient Malignant Peripheral Nerve Sheath Tumors https://www.biorxiv.org/content/10.1101/2025.11.05.686792v1

phylobar: an R package for multiresolution compositional barplots in omics studies https://www.biorxiv.org/content/10.1101/2025.11.05.686662v1

Alterations in protein N-glycosylation confer vanadate resistance in Ogataea polymorpha mutants defective in phosphomannosylation https://www.biorxiv.org/content/10.1101/2025.11.05.686784v1

A novel allele of Sh1 underlines the conversion of waxy corn to wx-sweet corn https://www.biorxiv.org/content/10.1101/2025.11.05.686684v1