In no way does staying up till midnight require a cup of tea these days! 🤦‍♂️ #NYE2025

I don't understand bursts of fireworks going off outside my window in London several hours before midnight. Do people celebrate New Year in other time zones?! 🤷🎆 #NYE2025

What viruses are up your nose? We asked 50 volunteers to swab their noses every week for a year to find out #flutracking #COVID #rhinovirus #IDSky academic.oup.com/jid/advance-...

Discovery of the day.... Coco Pops scented bubble bath!! 😮

Endotypes and disease stratification are increasingly going to become a thing in #MedSky. Question is whether we'll be able to harness it for better, more appropriate treatments.

Interesting #food history piece - I need to try a pizza naan!!! (photo from the article) Naan: How the 'world's best bread' travelled from Islamic courts to our plates - BBC News www.bbc.co.uk/news/article...

Great to see this published by colleagues #KeepAntibioticsWorking #AMS supporting #HealthLiteracy

Interesting new paper on Enterococcus lactis (the species formerly known as Clade B E. faecium) 'The Mannose Phosphotransferase System in Enterococcus lactis Is Essential for Gastrointestinal Colonization' onlinelibrary.wiley.com/doi/abs/10.1...

Super cool - personalised drug adverse effects medicine! #MedSky

💊 Community pharmacists play a key role in tackling inappropriate antibiotic use! This study explores how they decide when and how to intervene to improve prescriptions: doi.org/10.1093/jaca... #AntibioticStewardship #Pharmacy #AMR #JACAMRNews #IDSky

“…the sharp decline in external financing underscores the need to reduce reliance on external health aid” www.thelancet.com/journals/lan...

Funny feeling this morning. Pre-Christmas there was a mad rush to get everything work-wise done on time, not enough days to do it all, etc etc... Now that the work engine has to temporarily re-start today, I yearn for more sofa time.... Maybe reflects that Christmas is a break & not a holiday!

Don't normally share case reports but not sure i've ever seen this combination of pathogens (Stenotrophomonas & TB) anywhere, let alone in a prostatic abscess!! #IDSky 🤯 www.cureus.com/articles/449...

This is a noble idea for the #TBSky research community. TBH could aim for this in any research field - studies often collect and bank far more material than is used. Question though is: how do you police access, MTAs, contracts, IP etc.. 🤯 #IDSky #MedSky #AcademicSky @lancetmicrobe.bsky.social

Survived the Christmas Eve supermarket trip. Came away with all the essentials, including Moroccan strawberries! Classic December / Christmas food... 🤔 🎄

Among adults with newly diagnosed, drug-sensitive #tuberculosis in high-burden countries, an mHealth program delivering text messages for tobacco cessation was associated with higher quit rates and lower short-term mortality than written advice alone. ja.ma/3MSeyms

I think we all need some good news for global health and infectious diseases!

Examples of common IV antibiotics and their sodium content: - Ampicillin: 731 mg/dose → 2,924 mg/day - Ceftriaxone: 55 mg/dose → 110 mg/day - Metronidazole: 324 mg/dose → 973 mg/day - Piperacillin-Tazobactam: 556 mg/dose → 1,668 mg/day - Vancomycin: 885 mg/dose → 1,770 mg/day

Other than jumbling up what acronyms like OPAT and COPATusually stand for in my world, this was a good study with a clear, if expected, message on safety benefit of oral antibiotics. #IDSky #ClinMicro #medsky

We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development. www.nature.com/articles/s41... A thread.

Great to see this out: new IDSA guidelines on management of complicated UTI. Listened to excellent @cmicomms.bsky.social podcast with @angelahuttner.bsky.social @erinmccreary.bsky.social @bwtrautner.bsky.social & Valéry Lavergne earlier this year explaining how it was put together! #UTISky #IDSky

I like this v much. Learning from radiation safety to minimise harm (personal & societal) of antibiotics #IDSky #MedSky #ClinMicro #AMR "ALARA in Antimicrobial Stewardship: Adapting Radiation Safety Principles to Address Antibiotic Overuse" @cidjournal.bsky.social academic.oup.com/cid/advance-...

🧵 Essential ID Papers for 2025: A Clinician’s Guide Each year brings a flood of amazing ID literature. Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines. 👇

Putting US flags that aren't quite big enough to hide the whole watermark was my favourite! 😅

Important reminder that despite their promise, phage therapy remains unlicensed. Doesn't mean we should avoid considering it, but patients need to be aware of the situation. Need to build evidence & safety base #IDSky @cmijournal.bsky.social www.clinicalmicrobiologyandinfection.org/article/S119...

Case speakers for the BIA Dilemmas in Critical Care Infections Day 2026 include: 🎙️ Beatriz Larru 🎙️ Dagan Lonsdale 🎙️ Tom Hellyer and more… Find the full programme here 👉 fitwise.eventsair.co... #Infection #CriticalCareInfections #BIADilemmasDay2026

NEW PREPRINT! We systematically reviewed molecular epidemiology studies looking at strain discordance in pairs of people with TB disease and history of household contact We found 30 studies from 18 countries. Excluding 4 studies at high risk of bias, we had data on 1544 household case pairs [1/n]

Pears is indeed an architecturally inspiring research building to work in. Views were even better in autumn, but @fratorelli.bsky.social deep down I'm holding out for my first spring sights from there. You'll have to come back! 😉

this is really rather beautiful 🎄 www.bbc.co.uk/news/article...

In a phase 2a, randomized trial, oral treatment with high-dose mosnodenvir, a pan–DENV serotype antiviral drug, led to a significantly lower DENV-3 RNA load than placebo after challenge in a controlled human infection model. Full trial results: nej.md/48eUJwJ #MedSky #IDSky

Australia’s latest cervical cancer report is wild: Zero cases in women under 25 for the first time ever — a milestone researchers say is almost entirely due to HPV vaccination. But vaccination rates are slipping, and experts warn urgent #BlueSky #NewsSky #MedSky #SciSky #IDSky #ObSky #PedsSky

Kudos to the funding body that has asked me to review a grant with a deadline TWO MONTHS away, well after Christmas (school) holidays. Thank you, and makes me far more likely to accept. 👏 #AcademicSky

A new NEJM paper just dropped evaluating a quadrivalent modified mRNA (modRNA) influenza vaccine in a phase 3 trial. This is the largest test yet of whether the mRNA platform that transformed COVID-19 vaccination can improve our fight against flu. www.nejm.org/doi/full/10....

Happy to share our new AMR resource which has phenotypic AMR (usually MIC data) collected from publications and databases. This is paired with assemblies and annotations We're excited for users who might train new models, find phenotype/genotype mismatches, or any other use

👇👇Last days to submit your abstract to be considered for a short talk! Deadline 24 November!https://www.keystonesymposia.org/conferences/conference-listing/meeting/travel/c42026

Errr... What?! Am I?! #IDSky #ClinMicro #AMR #WAAW Great doodles @drrossanarosa.bsky.social 👏

I love pistachio ice cream, so was drawn to this Perspective piece in @nejm.org In fact, it's actually a very touching piece about medical & nursing staff connecting with patients' dying wishes. Reminder that medicine is both a science and an art... 🙏 #MedSky www.nejm.org/doi/full/10....

This was a great lecture, and I learnt a lot about toxoplasmosis that I never knew! #IDSky #MedSky

Post-TB lung disease - the impact of TB on patients does not end with the course of antibiotics, characterised by substantial long-term pulmonary impairment. Proposed case definition to support assessments and interventions in research studies 👇 #TBSky #IDSky @thelancetinfdis.bsky.social

A reasonable worked example how #AI can assist, not necessarily replace, human input in clinical service - pulling up and summarising events in a patient's journey is laborious and prone to error. Focusing human input on determining relevance of these data seems better use of time #IDSky

Still trying to get my head round what this model is predicting, as usually at least some clinical information is provided with microbiology samples. #AI #IDSky #ClinMicro #UTISky #AMR @bsacandjac.bsky.social academic.oup.com/jac/advance-...

Very pleased to plug our latest preprint, lead author @microberamon.bsky.social - fantastic collaboration with labs of Dario Carugo (Oxford) and Martha Clokie (Leicester) https:// - and others #UTISKy #UTI #IDSky #MicroSky www.biorxiv.org/content/10.1101/2025.11.12.688052v1 more below👇🧵

Highly recommend signing up for the Advance-ID bacterial and fungal infections newsletter. Thorough review of literature over past 2 weeks including critical analysis of RCTs. #IDSky www.advance-id.network forms.cloud.microsoft/pages/respon...

Coincidentally, this cool phage preprint carries on a theme that’s been stuck in my head this week about allowing pathogens to do interesting genetics for you in a way that clumsy humans might struggle to replicate by design #MicroSky cc @gpollara.bsky.social

Penicillin allergy de-labelling needs to be a core part of healthcare workers’ roles for it to be prioritized: doi.org/10.1093/jaca... #JACAMRNews #IDSky

Hot off the press at @thelancetinfdis.bsky.social: our paper diving into non-adherence in the BALANCE trial. We identify factors associated with protocol non-adherence, and evaluate the impact of potential bias on trial results. authors.elsevier.com/a/1m5He5E-Uo... @steventong.bsky.social #IDSky

Should I Worry About the Pasta? The ID Doctor as News Translator (Hello #IDSky and #Medsky! Trying out some different venues for writing, so hoping you'll subscribe -- it's free!) open.substack.com/pub/paulsaxm...

If anyone knows London, this is a fascinating throught experiment of what would have been.... @jim.londoncentric.media www.londoncentric.media/p/london-rin...

Flu is coming soon. That epi curve looks a bit ominous. #IDSky Good explainer article & public health message 👇 www.bbc.co.uk/news/article...

Sign of (my advancing) age - i may have to start banning my students writing any text using "xxx Light" fonts! 👓🔍