James Connolly
@ruamicro.bsky.social
📤 884
📥 468
📝 18
MRC Career Development Fellow at Newcastle University. Studying how pathogens control their genes
pinned post!
Absolutely delighted to share the labs latest work. We identify and characterise two pathways for D-ribulose utilisation in pathogenic EHEC and Citrobacter.
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Convergent evolution of distinct D-ribulose utilisation pathways in attaching and effacing pathogens - Nature Communications
Cottam et al. identify distinct pathways for D-ribulose utilisation in pathogenic Escherichia coli and Citrobacter rodentium, providing mechanistic details and suggesting convergent evolution towards ...
https://www.nature.com/articles/s41467-025-62476-5
4 months ago
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reposted by
James Connolly
Wiep Klaas Smits (ExpBac/CMAT)
7 days ago
🚨 Publication alert! We are stoked to report the structural basis for activity of a novel class of antimicrobials targeting Gram positive priority pathogens in
@natcomms.nature.com
. There is something for everyone on this paper, and I will highlight a few things below 👇 1/9
doi.org/10.1038/s414...
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A unique inhibitor conformation selectively targets the DNA polymerase PolC of Gram-positive priority pathogens - Nature Communications
In this work, Urem et al. characterize the mode of action as well as mechanism of reduced susceptibility related to a class of antimicrobials that is in development for the treatment of infections wit...
https://doi.org/10.1038/s41467-025-65324-8
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James Connolly
Microbes in Health and Disease
10 days ago
Looks like a great meeting :)
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Registration is now LIVE for the 2026 international symposium on Shiga toxin producing E. coli (VTEC), being held in Aberdeen on the the 10-13th of May 2026. The early bird deadline is February 27th so don’t miss out and register now.
www.vtec2026.org
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About - (VTEC 2026) International Symposium On Shiga Toxin Producing Escherchia Coli Infections - P&J Live
https://www.vtec2026.org
10 days ago
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reposted by
James Connolly
Nicky O’Boyle
10 days ago
Fantastic PhD opportunity 👇
add a skeleton here at some point
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reposted by
James Connolly
Alistair Brown
13 days ago
PhD opportunity with me and
@kshbeckham.bsky.social
www.findaphd.com/phds/project...
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MRC DiMeN Doctoral Training Partnership: Structural and Functional Analysis of Drug Resistance in Tuberculosis via a Novel MmpL3 Binding Site at Newcastle University on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Structural and Functional Analysis of Drug Resistance in Tuberculosis via a Novel MmpL3 Binding Site at Newcastle University, listed on FindAPhD....
https://www.findaphd.com/phds/project/mrc-dimen-doctoral-training-partnership-structural-and-functional-analysis-of-drug-resistance-in-tuberculosis-via-a-novel-mmpl3-binding-site/?p189475
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reposted by
James Connolly
Kate Beckham
11 days ago
Want to find ways to combat TB? Check out this PhD position 👇
add a skeleton here at some point
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reposted by
James Connolly
Alessandra Dantas
13 days ago
Want to work within a multidisciplinary group to combat antifungal resistance in Candida spp? Fully-funded MRC PhD studentship in collaboration with
@nclfungalgroup.bsky.social
and Francesco Del Carratore on the mode of action of a new class of antifungal drugs.
www.findaphd.com/phds/project...
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MRC DiMeN Doctoral Training Partnership: Targeting thioredoxin reductase to combat antifungal resistance in Candida spp. at Newcastle University on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Targeting thioredoxin reductase to combat antifungal resistance in Candida spp. at Newcastle University, listed on FindAPhD.com
https://www.findaphd.com/phds/project/mrc-dimen-doctoral-training-partnership-targeting-thioredoxin-reductase-to-combat-antifungal-resistance-in-candida-spp/?p189446
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reposted by
James Connolly
Kevin Whitley
13 days ago
Interested in a PhD at the intersection of biophysics and microbiology? Apply for this MRC-funded opportunity at Newcastle University to do cutting-edge microscopy in Mycobacterium tuberculosis! 🔬🦠 Closing 4 Dec!
www.findaphd.com/phds/project...
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MRC DiMeN Doctoral Training Partnership: Molecular mechanism of slow growth and antibiotic tolerance in Mycobacterium tuberculosis using single-molecule microscopy at Newcastle University on FindAPhD....
PhD Project - MRC DiMeN Doctoral Training Partnership: Molecular mechanism of slow growth and antibiotic tolerance in Mycobacterium tuberculosis using single-molecule microscopy at Newcastle Universit...
https://www.findaphd.com/phds/project/mrc-dimen-doctoral-training-partnership-molecular-mechanism-of-slow-growth-and-antibiotic-tolerance-in-mycobacterium-tuberculosis-using-single-molecule-microscopy/?p189436
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If you are interested in researching how drug resistant bacteria evade killing by our immune system, them this PhD project is for you. Come join the our team at Newcastle, in collaboration with University of Liverpool, and lead research at the interface of microbiology, immunology and metabolomics.
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MRC DiMeN Doctoral Training Partnership: Hiding in plain sight: How multi-drug resistant pathogens evade detection and killing by human neutrophils at Newcastle University on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Hiding in plain sight: How multi-drug resistant pathogens evade detection and killing by human neutrophils at Newcastle University, listed on Fin...
https://www.findaphd.com/phds/project/mrc-dimen-doctoral-training-partnership-hiding-in-plain-sight-how-multi-drug-resistant-pathogens-evade-detection-and-killing-by-human-neutrophils/?p189404
11 days ago
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reposted by
James Connolly
Andreas Haag
13 days ago
Exciting PhD opportunity with a great supervisor
@ruamicro.bsky.social
.
www.findaphd.com/phds/project...
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MRC DiMeN Doctoral Training Partnership: Hiding in plain sight: How multi-drug resistant pathogens evade detection and killing by human neutrophils at Newcastle University on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Hiding in plain sight: How multi-drug resistant pathogens evade detection and killing by human neutrophils at Newcastle University, listed on Fin...
https://www.findaphd.com/phds/project/mrc-dimen-doctoral-training-partnership-hiding-in-plain-sight-how-multi-drug-resistant-pathogens-evade-detection-and-killing-by-human-neutrophils/?p189404
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reposted by
James Connolly
Oded Rechavi
29 days ago
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
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reposted by
James Connolly
Serge Mostowy
about 1 month ago
Enhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei
@sydneylmiles.bsky.social
@katholt.bsky.social
🙏to transformative collaborative effort
www.nature.com/articles/s41...
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reposted by
James Connolly
Conlon Lab
about 1 month ago
Delighted to share our latest paper - A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics. Excellently led by Dr. Kuan-Yi Lu. We think it's a great proof-of-concept that altering immune cell behavior can make antibiotics work better
www.nature.com/articles/s41...
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A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics - Nature Microbiology
The authors developed a screen to find compounds that modulate intracellular Staphylococcus aureus metabolism and discovered KL1, which sensitizes persisters to antibiotics by reversing host-induced tolerance.
https://www.nature.com/articles/s41564-025-02124-2
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reposted by
James Connolly
Jörg Vogel
about 1 month ago
Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.
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reposted by
James Connolly
Tracy Palmer
about 1 month ago
Check it out! A proper team effort from past and present group members and a great collaboration with
@sergemostowylab.bsky.social
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reposted by
James Connolly
Justine Rudkin
about 1 month ago
PhD opportunity to come and work in Glasgow, developing advanced tissue culture models to study Staphylococcus aureus colonisation and infection
#microsky
#PhD
#DTPprogram
Enquiries from potential applicants are welcome.
www.gla.ac.uk/postgraduate...
www.findaphd.com/phds/program...
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University of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Understanding Pathogens, from Molecules to Phenotypes - Justine Rudkin
https://www.gla.ac.uk/postgraduate/doctoraltraining/northwestbio/projects/pathogens/justinerudkin/
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reposted by
James Connolly
Andy Edwards
about 1 month ago
Now published!
www.nature.com/articles/s41...
Very nice collaboration with Hoogenboom (
@ucl.ac.uk
) and Bonev (
@uniofnottingham.bsky.social
) labs.
add a skeleton here at some point
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reposted by
James Connolly
Chris Stewart
4 months ago
Introducing a new gut microbiology journal, aptly titled Gut Microbiology. All Article Publishing Charges (APCs) are waived for 2 years! Please send your exciting research our way.
www.sciencedirect.com/journal/gut-...
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reposted by
James Connolly
Westermann Lab
2 months ago
New preprint from the lab, in collaboration with Wenhan Zhu (U Vanderbilt): using dual RNA-seq during B. theta colonization of the host mucous layer, we identify IroR--an iron-response sRNA that tunes capsule expression and facilitates adaptation to iron limitation.
doi.org/10.1101/2025.09.08.672848
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An RNA regulates iron homeostasis and host mucus colonization in Bacteroides thetaiotaomicron
Symbiotic bacteria in the human intestinal microbiota provide many pivotal functions to human health and occupy distinct biogeographic niches within the gut. Yet the molecular basis underlying niche-s...
https://doi.org/10.1101/2025.09.08.672848
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reposted by
James Connolly
José R Penadés
2 months ago
Thrilled to share our two latest papers with the
@tcostalab.bsky.social
lab! In the first, we uncover a new mechanism of satellite transfer: cf-PICIs hijack tails from diverse phages to spread across species.
@imperialcollegeldn.bsky.social
www.cell.com/cell/fulltex...
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Chimeric infective particles expand species boundaries in phage-inducible chromosomal island mobilization
Capsid-forming PICIs (cf-PICIs) produce their own capsids and exploit phage tails from unrelated species to transfer their DNA across bacterial hosts. This tail piracy enables broad dissemination and ...
https://www.cell.com/cell/fulltext/S0092-8674%2825%2900974-2
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reposted by
James Connolly
José R Penadés
2 months ago
Our second paper with
@tcostalab.bsky.social
and GoogleDeepMind reports our experience with Google’s co-scientist: remarkably, the AI independently recapitulated our experimental discovery on cf-PICIs, showcasing AI’s potential to accelerate biology.
www.cell.com/cell/fulltex...
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AI mirrors experimental science to uncover a mechanism of gene transfer crucial to bacterial evolution
By solving a previously unsolved biological question, the AI co-scientist predicted a complex mechanism of gene transfer and generated hypotheses that opened new research directions, illustrating AI's...
https://www.cell.com/cell/fulltext/S0092-8674%2825%2900973-0
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reposted by
James Connolly
Zeynep Baharoglu
2 months ago
So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary
@manonlang.bsky.social
with
@fox-science.bsky.social
&
@amazeld.bsky.social
+amazing collaborators
@immunobladder.bsky.social
@imaneelmeouche.bsky.social
🦠 We believe it can make a difference in
#AMR
infections!
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Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters
Uridine boosts aminoglycoside treatment efficiency against antibiotic-susceptible as well as antibiotic-resistant E. coli strains.
https://www.science.org/doi/10.1126/sciadv.adw7630
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reposted by
James Connolly
Gavin Thomas (he/him)
2 months ago
Delighted with our new paper on a novel itaconate transporter in the human pathogen Pseudomonas aeruginosa, led by Javeria and Reyme.
@ybri-uoy.bsky.social
@javeriamehboob.bsky.social
@bethkw.bsky.social
A duplicated transporter on its way to itaconate selectivity
portlandpress.com/biochemj/art...
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Itaconate utilisation by the human pathogen Pseudomonas aeruginosa requires uptake via the IctPQM TRAP transporter
Pseudomonas aeruginosa PA01 is one of the major causes of disease persistence and mortality in patients with lung pathologies, relying on various host metabolites as carbon and energy sources for grow...
https://portlandpress.com/biochemj/article/482/17/BCJ20253132/236479/Itaconate-utilisation-by-the-human-pathogen
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reposted by
James Connolly
Emmanuele Severi
3 months ago
www.biorxiv.org/content/10.1...
#microsky
#synbio
#ecoli
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A compact vector for scarless gene editing in E. coli
Here we present pCASKD, a single-plasmid system for scarless chromosomal editing in Escherichia coli. Our plasmid pCASKD integrates CRISPR-Cas9-mediated counterselection, Lambda-Red recombineering, an...
https://www.biorxiv.org/content/10.1101/2025.08.05.668820v1
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reposted by
James Connolly
Microbiology Society
3 months ago
Applications for Outreach and Engagement grant are now open. Eligible members can apply for up to £1000 to support science outreach or public engagement initiatives. Check your eligibility and apply before 01 Oct 25 at 23.59 BST.
microb.io/OutreachandE...
.
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Outreach and Engagement Grant
Eligible members can apply for up to £1000 to support relevant science outreach or public engagement initiatives that engage new audiences in the art and science in any aspect of microbiology.…
https://microb.io/OutreachandEngagementGrant
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reposted by
James Connolly
Katy Patras
4 months ago
Excited to share a new preclinical model, human bladder organoids, to study UTI, novel therapies, and beyond! Developed with Dr. Sarah Blutt, the BCM Organoid Core, and
@tailor-labs.bsky.social
www.biorxiv.org/content/10.1...
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Human bladder organoids model urinary tract infection and bacteriophage therapy
Urinary tract infections (UTIs), primarily caused by uropathogenic Escherichia coli (UPEC), are among the most common antibiotic-resistant infections. Despite this, currently available preclinical UTI...
https://www.biorxiv.org/content/10.1101/2025.07.30.667685v1
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Absolutely delighted to share the labs latest work. We identify and characterise two pathways for D-ribulose utilisation in pathogenic EHEC and Citrobacter.
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Convergent evolution of distinct D-ribulose utilisation pathways in attaching and effacing pathogens - Nature Communications
Cottam et al. identify distinct pathways for D-ribulose utilisation in pathogenic Escherichia coli and Citrobacter rodentium, providing mechanistic details and suggesting convergent evolution towards ...
https://www.nature.com/articles/s41467-025-62476-5
4 months ago
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reposted by
James Connolly
Julie A. K. McDonald
4 months ago
In case you missed it, check out our latest paper describing how vancomycin-resistant enterococci exploit antibiotic-mediated killing of gut commensals to grow in nutrient-enriched and metabolite-depleted intestines:
doi.org/10.1038/s414...
#AMR
#GutMicrobiome
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Vancomycin-resistant enterococci utilise antibiotic-enriched nutrients for intestinal colonisation - Nature Communications
Here, the authors show that vancomycin-resistant enterococci grow in the antibiotic-treated gut microbiome by utilising enriched nutrients in the presence of reduced concentrations of inhibitory micro...
https://doi.org/10.1038/s41467-025-61731-z
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James Connolly
Andreas Bäumler
4 months ago
Meet the new Editor in Chief of mSystems
journals.asm.org/doi/10.1128/...
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Humanity’s urgent challenges need solutions from systems microbiology | mSystems
It is with great excitement and sincere dedication that I assume the role of editor in chief of mSystems. Building on the momentum and reputation that mSystems has achieved in its first decade, we wil...
https://journals.asm.org/doi/10.1128/msystems.00838-25?utm_source=literatum
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reposted by
James Connolly
Malcolm White
4 months ago
Jo Hobbs
@hobbslabmicro.bsky.social
has a 12 month Postdoc available on mechanisms of antibiotic tolerance. More details here:
www.vacancies.st-andrews.ac.uk/Vacancies/W/...
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reposted by
James Connolly
Hannah Ledvina Ph.D.
4 months ago
Words cannot describe how excited I am to share the findings from the second half of my postdoc in
@aaronwhiteley.bsky.social
's lab where we discover that bacteria use functional amyloids to defend themselves from predatory bacteria.
rdcu.be/euu5Y
. See thread for details on this epic adventure 1/.
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Functional amyloid proteins confer defence against predatory bacteria
Nature - Escherichia coli uses curli fibres, oligomers of the functional amyloid CsgA, as a barrier to protect against the predatory bacteria Bdellovibrio bacteriovorus and Myxococcus xanthus in a...
https://rdcu.be/euu5Y
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James Connolly
Kimberly Kline 🏔
4 months ago
🔬Calling all microbiologists. 🔬 Ever feel like your paper is too small for some journals, but too solid to sit on?
#FEMSMicrobes
welcomes well-executed microbiology manuscripts, and they put special attention on promoting ECR authors, eg the webinar below. 👇
@femsjournals.bsky.social
@femsmicro.org
add a skeleton here at some point
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reposted by
James Connolly
Willem van Schaik
5 months ago
I am delighted that our manuscript 'Staphylococcus haemolyticus is a reservoir of antibiotic resistance genes in the preterm infant gut' is now published.
www.tandfonline.com/doi/full/10....
Big thank you to all co-authors, particularly
@lisalamberte.bsky.social
and
@halllab.bsky.social
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Staphylococcus haemolyticus is a reservoir of antibiotic resistance genes in the preterm infant gut
Staphylococcus haemolyticus is an important cause of sepsis in preterm infants, with gut colonization being recognized as a risk factor for infection. To better understand the diversity of S. haemo...
https://www.tandfonline.com/doi/full/10.1080/19490976.2025.2519700
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James Connolly
Hall Lab
5 months ago
Amazing to see this now published! Congrats to
@lisalamberte.bsky.social
and
@wvschaik.bsky.social
- on leading this important
#microbiome
study on
#AMR
and Staphylococcus haemolyticus in the preterm gut 👇
add a skeleton here at some point
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reposted by
James Connolly
Westermann Lab
5 months ago
Our latest:
www.cell.com/cell-reports/fulltext/S2211-1247(25)00615-1
. Links Bacteroides cell size w/ gene expression. Protocol works even for single cells. 🦠 Shoutout to
@elisebor.bsky.social
,
@emmanuel-saliba.bsky.social
,
@lbarquist.bsky.social
,
@jorg-vogel-lab.bsky.social
, Till Strowig & KC Huang.
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Low-input RNA-seq suggests metabolic specialization underlying morphological heterogeneity in a gut commensal bacterium
Bornet et al. investigate the morphological heterogeneity of Bacteroides thetaiotaomicron cells observed both in laboratory culture and inside the mammalian GI tract. The authors show that cell size i...
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00615-1
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reposted by
James Connolly
Jan-Willem Veening
5 months ago
Some positive news in troubled times: New preprint by Vincent de Bakker, Xue Liu
@jonbakerlab.bsky.social
Infection-mimicking conditions+transcriptomics/proteomics/'essentialomics'/lipidomics shows many cool things!
www.biorxiv.org/content/10.1...
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Multi-omics profiling reveals atypical sugar utilization and identifies a key membrane composition regulator in Streptococcus pneumoniae
The human body comprises many different microenvironments, each with their own challenges for microorganisms to overcome in order to survive, and possibly cause infection. The human pathogen Streptoco...
https://www.biorxiv.org/content/10.1101/2025.06.13.659575v1
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James Connolly
Rebecca McHugh
7 months ago
Absolutely delighted to share that I've been awarded the BBSRC Fellowship to continue my working on antivirulence drugs at the University of Glasgow. A massive thank you to all of my mentors and collaborators. I can't wait to see what the future holds for the project 🔬
add a skeleton here at some point
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reposted by
James Connolly
Prof Jenny Rohn
7 months ago
🔈🎉 I will soon be advertising a postdoc in my friendly London lab, funded by MRC
@ukri.org
, to decipher uropathogen virulence and host response pathways in our 3D-UHU human urothelial model! A great collaboration with co-Is
@gpollara.bsky.social
and
@scottishwormboy.bsky.social
#UTISky
#UTI
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reposted by
James Connolly
Professor Andrew J Roe
8 months ago
New paper from the group - here we show that aurodox prevents shiga toxin mediated damage in a murine model. Interesting changes to the microbiota too. Amazing work by
@rebeccamchugh.bsky.social
and the group. Paper here-
rdcu.be/efW0K
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reposted by
James Connolly
Andreas Bäumler
8 months ago
🔬🦠 How to make sense of the taxonomic complexity & interpersonal variability of the gut microbiota? We propose that beneath this complexity lies a hierarchy of factors that control gut microbiota assembly. Read more!
#Microbiome
#GutHealth
authors.elsevier.com/a/1km32_,2Ci...
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James Connolly
Dr Katherine Duncan
8 months ago
One week left to apply for this BBSRC funded PhD position in the Duncan lab, cosupervised by
@thecopperdoctor.bsky.social
and
@ruamicro.bsky.social
www.findaphd.com/phds/project...
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Antibiotics from the abyss – assessing the impact of deep-sea mining on biodiscovery at Newcastle University on FindAPhD.com
PhD Project - Antibiotics from the abyss – assessing the impact of deep-sea mining on biodiscovery at Newcastle University, listed on FindAPhD.com
https://www.findaphd.com/phds/project/antibiotics-from-the-abyss-assessing-the-impact-of-deep-sea-mining-on-biodiscovery/?p182723
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reposted by
James Connolly
CBCB Newcastle
8 months ago
Antibiotics from the abyss; assessing the impact of deep-sea mining on biodiscovery. Supervised by
@kateduncan.bsky.social
,
@thecopperdoctor.bsky.social
and
@ruamicro.bsky.social
.
www.findaphd.com/phds/project...
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Antibiotics from the abyss – assessing the impact of deep-sea mining on biodiscovery at Newcastle University on FindAPhD.com
PhD Project - Antibiotics from the abyss – assessing the impact of deep-sea mining on biodiscovery at Newcastle University, listed on FindAPhD.com
https://www.findaphd.com/phds/project/antibiotics-from-the-abyss-assessing-the-impact-of-deep-sea-mining-on-biodiscovery/?p182723
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reposted by
James Connolly
CBCB Newcastle
8 months ago
Microbial metal-head: the integrated roles of metal homeostasis in host-pathogen interaction. Supervised by
@ruamicro.bsky.social
,
@thecopperdoctor.bsky.social
and Manuel Banzhaf.
www.findaphd.com/phds/project...
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Microbial metal-head: the integrated roles of metal homeostasis in host-pathogen interaction at Newcastle University on FindAPhD.com
PhD Project - Microbial metal-head: the integrated roles of metal homeostasis in host-pathogen interaction at Newcastle University, listed on FindAPhD.com
https://www.findaphd.com/phds/project/microbial-metal-head-the-integrated-roles-of-metal-homeostasis-in-host-pathogen-interaction/?p182732
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Still time to apply for this PhD position with our team!
add a skeleton here at some point
8 months ago
0
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Fully funded PhD position available to join our team! We will focus on untangling the molecular mechanisms used by pathogenic, antibiotic resistant E.coli to colonise the host gut. Highly interdisciplinary project in collaboration with
@thecopperdoctor.bsky.social
and Manu Banzhaf. Please share
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Microbial metal-head: the integrated roles of metal homeostasis in host-pathogen interaction at Newcastle University on FindAPhD.com
PhD Project - Microbial metal-head: the integrated roles of metal homeostasis in host-pathogen interaction at Newcastle University, listed on FindAPhD.com
https://www.findaphd.com/phds/project/microbial-metal-head-the-integrated-roles-of-metal-homeostasis-in-host-pathogen-interaction/?p182732
9 months ago
0
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reposted by
James Connolly
Giusy Mariano
9 months ago
We have extended the deadline for this! If you are passionate about phage-bacteria interactions, check this out and join us!
add a skeleton here at some point
0
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Brilliant opportunity to work with Alex and my team on our collaborative project. Don’t hesitate to apply!
add a skeleton here at some point
9 months ago
0
2
1
reposted by
James Connolly
Tracy Palmer
9 months ago
Fab new study from
@ruamicro.bsky.social
and team!
add a skeleton here at some point
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reposted by
James Connolly
Andy Goodman
9 months ago
Starting my Bluesky adventure by highlighting a new paper from the lab!
add a skeleton here at some point
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reposted by
James Connolly
Zeynep Baharoglu
9 months ago
Control of a gene transfer agent cluster in Caulobacter crescentus by transcriptional activation and anti-termination
#microsky
🦠
#bmsv
from
@tunglejic.bsky.social
lab
www.biorxiv.org/content/10.1...
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Control of a gene transfer agent cluster in Caulobacter crescentus by transcriptional activation and anti-termination
Gene Transfer Agents (GTAs) are domesticated prophages that cannot self-multiply and be infectious but might have been co-opted to perform biological functions for the host bacteria. Caulobacter cresc...
https://www.biorxiv.org/content/10.1101/2023.11.12.565669v2
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