non-correlating mRNA-protein levels during stress 🦠

Great talk from @hobbslabmicro.bsky.social - thank you for visiting @mhd-newcastle.bsky.social and telling us why antibiotic tolerance is so important

Another brilliant opportunity to work the fantastic Andreas in St Andrews!

Like bacteria, phages use sRNAs to regulate gene expression! Out today in @cp-trendsmicrobiol.bsky.social, @mvelascogomariz.bsky.social and I highlight a recent RIL-seq study from the @saharmelamed.bsky.social lab that looked into posttranscriptional regulation of lambda! tinyurl.com/lambda-RIL-seq

Last chance to apply for this exciting PhD with us. Deadline tomorrow the 27th of February!

Superb opportunity to learn from one of the smartest scientists I know. And a lovely place to live so what’s not to like! Apply now!

Early bird registration for VTEC 2026 ends this Friday (February 27th). Please share with your networks and consider registering for this great One-health conference covering all topics VTEC related, taking place in Aberdeen on the 10-13th of May.

What if quorum sensing doesn’t promote biofilms - but restrains it? 🤔 New work from @harisantypas.bsky.social shows that the Fsr QS system in Enterococcus faecalis acts as a brake on biofilm formation and pathogenesis during infective endocarditis (IE). www.nature.com/articles/s41...

Recurrent and chronic UTIs have a huge impact on patient's quality of life and is an area of research which is often overlooked and understudied. There are massive gaps in our understanding which we can fill to... (1/3) See all images in this post and that follow for the top 10! #MicroSky #UTISky

Mechanism and reconstitution of circadian transcription in cyanobacteria in @natsmb.nature.com by Mingxu Fang et al from Sudan Golden @kevincorbett.bsky.social Yulia Yuzenkova www.nature.com/articles/s41...

@ewarman.bsky.social has followed up on her discovery of bidirectional promoters in bacteria by defining their basic rules for regulation and links to gene expression noise... academic.oup.com/nar/article/...

In our most recent work David Forrest has discovered a widespread mechanisms linking transcription initiation to DNA supercoiling... www.nature.com/articles/s41...

🔔Collabator Alert🔔 I’m putting together a project on UTIs and the urogenital microbiome and am looking for a collaborator with solid metagenomic sequencing/analysis experience. If you’d be interested in joining the work, I’d love to talk #MicroSky #UTISky

Still lots of time to apply for this exciting project with us. Please share and encourage interested students to get in touch.

Or this one: how metals influence host-bacteria interactions in the gut, with @ruamicro.bsky.social and @banzhaflab.bsky.social at Newcastle. www.findaphd.com/phds/project...

Lots of PhD opportunities for UK + international students involving my lab. Topics relate to metals & microbiology. First up: TonB-dependent receptors in commensal Neisseria in my lab at Durham, with @kjosts.bsky.social and @mattbashton.bsky.social. www.findaphd.com/phds/project...

PhD position available in our team to study how UPEC exploits metals to successfully colonise the host gut. Cool collaboration with @thecopperdoctor.bsky.social and @banzhaflab.bsky.social Please share and get in touch for more details

New preprint from my lab (with Arya Kaul, @fernpizza.bsky.social, and @brinda.eu), in which we explore new genes hitchhiking on the beneficial deletion that fused them together, and find them in the LTEE, M. Tb/bovis, and across the bacterial tree of life

We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development. www.nature.com/articles/s41... A thread.

#MachineLearning methods are used to predict #AntimicrobialResistance #AMR from genomic data. @lbarquist.bsky.social &co show that sampling biases driven by population structure severely undermine the accuracy of AMR prediction models even with large datasets @plosbiology.org 🧪 plos.io/4iZ0zXQ

There is still Time to submit an abstract for VTEC 2026! Don’t miss out on the opportunity to present your work on any aspect of VTEC at this longstanding meeting!

Finally out! Right on time for the holidays 🎄🎁 Big thanks to Nick Scott, @giseladivenanzio.bsky.social, Clay and Mario @feldmanlab.bsky.social who made it happen! www.pnas.org/doi/10.1073/...

Join our live webinar today at 16:00 (GMT) to hear more about the VTEC conference, and why you should come. STEC/VTEC continues to be priority pathogen. The aim is to share cutting-edge scientific knowledge, addressing the questions about why the outbreaks occur and how best to manage this pathogen.

Fantastic to have Prof Matthias Wilmanns from EMBL Hamburg hosted by @kshbeckham.bsky.social to give a @mhd-newcastle.bsky.social seminar on mycobacterial infection #dreamtheme

💎MRC AIM PhD advert💎 Uncharted territory - the Akkermansia muciniphila import system. Liang Wu, David Tourigny, and I are looking for someone to work on how A. muciniphila imports mucin. www.findaphd.com/phds/project...

🔊 Interested in doing a PhD on RNA-binding proteins in an abundant microbiota species and becoming a member of the German Priority Programme “Illuminating Gene Functions in the Human Gut Microbiome”? Apply here: www.uni-wuerzburg.de/karriere/sin...

Today, we are lucky to have Imane El Meouche from IAME, France to give a MCM seminar @medicalsciencesncl.bsky.social (chaired by @henrikstrahl.bsky.social) on antibiotics tolerance in E. Coli

Why does daptomycin resistance appear so fast in Enterococcus? We finally have a clue. DAP resistance in enterococci pops up quickly. What’s been missing is why resistance-associated membrane changes look the way they do, and why the classic path of mutations is so predictable.

Fabulous opportunity to study phage biology with Andreas Haag in St Andrews. Don’t miss out.

Theres still time to apply for our PhD project on UPEC/immune cell interactions. Deadline December 4th

🚨 Publication alert! We are stoked to report the structural basis for activity of a novel class of antimicrobials targeting Gram positive priority pathogens in @natcomms.nature.com. There is something for everyone on this paper, and I will highlight a few things below 👇 1/9 doi.org/10.1038/s414...

Looks like a great meeting :)

Registration is now LIVE for the 2026 international symposium on Shiga toxin producing E. coli (VTEC), being held in Aberdeen on the the 10-13th of May 2026. The early bird deadline is February 27th so don’t miss out and register now. www.vtec2026.org

Fantastic PhD opportunity 👇

PhD opportunity with me and @kshbeckham.bsky.social www.findaphd.com/phds/project...

Want to find ways to combat TB? Check out this PhD position 👇

Want to work within a multidisciplinary group to combat antifungal resistance in Candida spp? Fully-funded MRC PhD studentship in collaboration with @nclfungalgroup.bsky.social and Francesco Del Carratore on the mode of action of a new class of antifungal drugs. www.findaphd.com/phds/project...

Interested in a PhD at the intersection of biophysics and microbiology? Apply for this MRC-funded opportunity at Newcastle University to do cutting-edge microscopy in Mycobacterium tuberculosis! 🔬🦠 Closing 4 Dec! www.findaphd.com/phds/project...

If you are interested in researching how drug resistant bacteria evade killing by our immune system, them this PhD project is for you. Come join the our team at Newcastle, in collaboration with University of Liverpool, and lead research at the interface of microbiology, immunology and metabolomics.

Exciting PhD opportunity with a great supervisor @ruamicro.bsky.social. www.findaphd.com/phds/project...

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

Enhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei @sydneylmiles.bsky.social @katholt.bsky.social 🙏to transformative collaborative effort www.nature.com/articles/s41...

Delighted to share our latest paper - A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics. Excellently led by Dr. Kuan-Yi Lu. We think it's a great proof-of-concept that altering immune cell behavior can make antibiotics work better www.nature.com/articles/s41...

Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.

Check it out! A proper team effort from past and present group members and a great collaboration with @sergemostowylab.bsky.social

PhD opportunity to come and work in Glasgow, developing advanced tissue culture models to study Staphylococcus aureus colonisation and infection #microsky #PhD #DTPprogram Enquiries from potential applicants are welcome. www.gla.ac.uk/postgraduate... www.findaphd.com/phds/program...

Now published! www.nature.com/articles/s41... Very nice collaboration with Hoogenboom ( @ucl.ac.uk ) and Bonev ( @uniofnottingham.bsky.social ) labs.

Introducing a new gut microbiology journal, aptly titled Gut Microbiology. All Article Publishing Charges (APCs) are waived for 2 years! Please send your exciting research our way. www.sciencedirect.com/journal/gut-...

New preprint from the lab, in collaboration with Wenhan Zhu (U Vanderbilt): using dual RNA-seq during B. theta colonization of the host mucous layer, we identify IroR--an iron-response sRNA that tunes capsule expression and facilitates adaptation to iron limitation. doi.org/10.1101/2025.09.08.672848