The 2026 Barkley Marathons began with one of the strongest fields ever. The starting field came from 15 Counties as well as 15 States, and included ten women. The course seemed not to care. Over 70% of the field is done. #BM100

A microscope that cost less than £50 and took under 3 hours to build using a common 3D printer could be transformative for students and researchers with limited funding

Exceptional young performers reached their peak quickly but narrowly mastered only one interest. By contrast, exceptional adults reached peak performance gradually with broader, multidisciplinary practice. However, elite programs are designed to nurture younger talent.

New preprint. Work led by @ainsley-beaton.bsky.social & Rebecca Devine. They show the highly conserved Streptomyces MtrAB two component system activates ectoine production and triggers sporulation in response to osmotic stress in Streptomyces venezuelae www.biorxiv.org/content/10.6...

bioRxiv by @ainsley-beaton.bsky.social from @matthutchings.bsky.social on the role of MtrAB in Streptomyces venezuelae

Delighted to see the main work from my PhD finally published in @mbio.bsky.social! It all started with the observation that deleting the cutRS two-component system in S. venezuelae caused this amazing explorer phenotype in the presence of glucose. But what was going on?! (1/n)

Very happy to see this remarkable work published. Led by @tommclean.bsky.social and @ainsley-beaton.bsky.social. We show how Streptomyces bacteria sense & respond to misfolded secreted proteins. A great collaboration with @barriewilks.bsky.social #microsky 1/2 journals.asm.org/doi/epub/10....

PhD opportunity to come and work in Glasgow, developing advanced tissue culture models to study Staphylococcus aureus colonisation and infection #microsky #PhD #DTPprogram Enquiries from potential applicants are welcome. www.gla.ac.uk/postgraduate... www.findaphd.com/phds/program...

It can only be a last day when there are this number of primers in the bin

Don’t know why I’d never thought of a commute coffee before now

8 am on a Monday. Do I just go home?

After a great week at #microbio25 I’m set up on the train with a good book and a coffee which is the perfect way to travel 📚. That’s if the last few nights of missing my 9pm bed time in favour of the pub don’t mean that I immediately fall asleep 🤣

@liam-rooney.bsky.social gave an incredibly interesting talk about novel imaging techniques for infection biology and that’s great BUT look at the tiny wee sad face inside this digitally cross sectioned and optically clear galleria is! It looks like how I feel in the mornings

And so begins a very long train journey from Norwich to Liverpool via every stop in between for Microsoc 2025

dussl's making headlines! 🌞 Why one Glaswegian is marketing SPF to Scotland's wettest city. heraldscotland.com/news/25028013.one-glaswegian-marketing-spf-scotlands-wettest-city/?ref=li

Very happy to share this work led by @tommclean.bsky.social and @ainsley-beaton.bsky.social. The conserved Streptomyces sensor kinase CutS senses disulphide bond formation outside the cell. If it fails CutS activates CutR which switches on production of foldase HtrA3 www.biorxiv.org/content/10.1...

Further insight into how CutRS functions in Streptomyces and some thoughts on how its redox state detection via conserved dual cysteine residues in the extra cellular domain of a sensor kinase may be present in almost all bacteria @tommclean.bsky.social @matthutchings.bsky.social

Redox control of antibiotic biosynthesis in Streptomyces. Remarkable work led by @katienoble241.bsky.social and Rebecca Devine demonstrates why antibiotic biosynthesis is often switched on in solid cultures and off in liquid. www.biorxiv.org/content/10.1...

First #toadwatch of the season and it was busy! 28 toads and 8 frogs were given a lift to the pond 🐸 Toads return to the pond they spawned in each year to breed, often covering great distances to do so. Due to habitat fragmentation they are increasingly killed by cars whilst on their journey

It’s official @tommclean.bsky.social and I have peaked in terms of our scientific writing 📄

Wonderfully artistic advertising from @microbesng.bsky.social. They are already my favourite sticker maker and now we may need to add posters and plasmid sequencing to that

Legitmately thrilled to share our latest work, in which @fernpizza.bsky.social solved an experimental challenge in plasmid biology as old as the field: measuring how plasmids compete and evolve within individual cells!

VACANCY - We’re seeking a Proteomics Scientist to work alongside our experienced platform manager to help serve the growing needs of proteomics-based technology at the John Innes Centre (JIC). www.jic.ac.uk/vacancies/pr... Closing date - 2 March 2025 Contract - Full-time, indefinite