1/9 New preprint from the Sternberg Lab in collaboration with the Nishimasu Lab! We uncover how the DRT3 antiphage immune system pairs two reverse transcriptases, one RNA-templated and one protein-templated, to build a double-stranded DNA effector. doi.org/10.64898/202...

Dr. Indra Gonzalez Ojeda gave a great thesis defense this morning, including some wisdom for starting PhD students, or frankly, anyone.

Oh my god why am I actually crying?

This Plasmid Project was directly inspired by the results on multilevel selection that Dan introduced me to! In this thread he explains some fundamental theoretical results that were so influential to me as a Scientist. Looking forward to more Math-driven experiments!!! Thanks Dan!

This is it!!! This is the work I never want to stop hearing about. Kepler’s creativity and curiosity really shine through in this paper. Give it a read and enjoy 😎

This has been an intense, crazy week. My plasmid competition paper is finally out and we have a new preprint on Bioarxiv! Plus I'm leaving the US after 10 years here. See you soon America! Hello Zurich!!!

The best dude:

When different kinds of mobile genetic elements get together, they become even more powerful catalysts for microbial evolution! In this work we discovered a mechanism by which Insertion Sequences drive their spread across Plasmids, which helps explain this evolutionary potential!

I'm so happy that I can finally share the results of my first postdoc paper with @baym.lol!!! Turns out plasmids are an amazing system to study multi-scale evolution and we can track within-cell and between-cell dynamics! (1/n) www.biorxiv.org/content/earl...