Grainger Lab
@graingerlab.bsky.social
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Bacterial chromosome biology, gene expression, pathogenicity... and football. www.graingerlab.com
@danielabarilla.bsky.social
kicking off
#BioPhyChrom2025
- a fantastic turn out too...
10 days ago
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Grainger Lab
Thiago Carvalho
about 2 months ago
'We show that the VqmAj homologs can indeed detect (host autoinducer) DPO and, in response, activate the lytic pathway. Our observation indicates that jVP882 is a member of a large family of globally-dispersed quorum-sensing-responsive temperate phages.'
www.biorxiv.org/content/10.1...
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A family of linear plasmid phages that detect a quorum-sensing autoinducer exists in multiple bacterial species
Temperate phages oscillate between lysogeny, a genomic maintenance state within a bacterial host, and lytic replication, in which the host is killed, and newly made phage particles are released. Succe...
https://www.biorxiv.org/content/10.1101/2025.07.30.667625v1
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Grainger Lab
Vicky Lioy
about 2 months ago
๐ข Dear lovers of prokaryotic chromosomes: Registration for the Biology & Physics of Chromosomes meeting has been extended until 7 August โณ. Join us!
@biophychrom.bsky.social
@danielabarilla.bsky.social
@damelab.bsky.social
@graingerlab.bsky.social
@biochemsoc.bsky.social
#microsky
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Talk slots full but we can take late breaking poster abstracts until August 7th. Hope to see you in York to hear about your chromosome story ๐งฌ๐ฆ ๐งซ
www.eventsforce.net/biochemsoc/f..
.
@vslioy.bsky.social
@damelab.bsky.social
@graingerlab.bsky.social
@biochemsoc.bsky.social
@biophychrom.bsky.social
2 months ago
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Grainger Lab
PLOS Biology
2 months ago
How are bacterial transport machineries regulated by external cues?
@brochadolab.bsky.social
&co identify environmental chemicals that regulate
#transporter
transcription, identifying the TF Rob as a key modulator of
#EffluxPump
expression in
#Ecoli
#AMR
@plosbiology.org
๐งช
plos.io/46pUM9Q
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Grainger Lab
Daniela Barillร
2 months ago
Just few days left to register for this chromosome biology fรชte! ๐งฌ๐งฌ๐งฌ โณ๐ 16 July
www.eventsforce.net/biochemsoc/f...
@vslioy.bsky.social
@damelab.bsky.social
@graingerlab.bsky.social
@biochemsoc.bsky.social
@biophychrom.bsky.social
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reposted by
Grainger Lab
Daniela Barillร
4 months ago
Chromosome Enthusiasts, join us at The Biology & Physics of Prokaryotic Chromosomes ๐งฌ! Friendly community, fantastic speakers line-up, grant writing session for ECRs. Early-bird deadline approaching soon.
@damelab.bsky.social
@vslioy.bsky.social
@graingerlab.bsky.social
@biophychrom.bsky.social
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Grainger Lab
Nature Microbiology
4 months ago
๐จ Out now! West African South American pandemic Vibrio cholerae encodes multiple distinct phage defence systems
#MicroSky
๐ฆ
#Phage
@mblokesch.bsky.social
www.nature.com/articles/s41...
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West AfricanโSouth American pandemic Vibrio cholerae encodes multiple distinct phage defence systems - Nature Microbiology
The West AfricanโSouth American lineage of Vibrio cholerae contains multiple distinct anti-phage defence systems that provide resistance to various phage families, including vibriophage ICP1, a key pr...
https://www.nature.com/articles/s41564-025-02004-9?utm_source=bluesky&utm_medium=social&utm_campaign=nmicrobiol
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reposted by
Grainger Lab
Daniela Barillร
4 months ago
Join us in York for the Biology & Physics of Prokaryotic Chromosomes! ๐งฌ
#Microsky
#Archaeasky
www.biochemistry.org/events-and-t...
@biochemsoc.bsky.social
@damelab.bsky.social
@graingerlab.bsky.social
@vslioy.bsky.social
add a skeleton here at some point
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reposted by
Grainger Lab
แฏIแTOแ แIแET, แฐแช
6 months ago
Fascinating new PLoS Biology paper from George Schaible et al in the Hatzenpichler Lab at Montana State โ๐๐ด ๐ต๐ฉ๐ฆ ๐ฐ๐ฏ๐ญ๐บ ๐ฆ๐น๐ข๐ฎ๐ฑ๐ญ๐ฆ ๐ฐ๐ง ๐ฃ๐ข๐ค๐ต๐ฆ๐ณ๐ช๐ข ๐ต๐ฉ๐ข๐ต ๐ฆ๐น๐ฉ๐ช๐ฃ๐ช๐ต ๐ฐ๐ฃ๐ญ๐ช๐จ๐ข๐ต๐ฆ ๐ฎ๐ถ๐ญ๐ต๐ช๐ค๐ฆ๐ญ๐ญ๐ถ๐ญ๐ข๐ณ๐ช๐ต๐บ, ๐๐๐ ๐ฑ๐ณ๐ฐ๐ท๐ช๐ฅ๐ฆ ๐ข๐ฏ ๐ช๐ฎ๐ฑ๐ฐ๐ณ๐ต๐ข๐ฏ๐ต ๐ฆ๐น๐ข๐ฎ๐ฑ๐ญ๐ฆ ๐ฐ๐ง ๐ฑ๐ฐ๐ด๐ด๐ช๐ฃ๐ญ๐ฆ ๐ฎ๐ฆ๐ค๐ฉ๐ข๐ฏ๐ช๐ด๐ฎ๐ด ๐ฃ๐ฆ๐ฉ๐ช๐ฏ๐ฅ ๐ต๐ฉ๐ช๐ด ๐ฑ๐ณ๐ฐ๐ง๐ฐ๐ถ๐ฏ๐ฅ ๐ด๐ต๐ฆ๐ฑ ๐ช๐ฏ ๐ญ๐ช๐ง๐ฆโ๐ด ๐ฆ๐ท๐ฐ๐ญ๐ถ๐ต๐ช๐ฐ๐ฏ๐ข๐ณ๐บ ๐ฉ๐ช๐ด๐ต๐ฐ๐ณ๐บ ๐ฐ๐ฏ ๐๐ข๐ณ๐ต๐ฉโ
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These Tiny Magnetic Bacteria Act Like a Single Body โ And Could Explain the Origins of Complex Life
Tiny magnetic bacteria that live in tightly bound groups are showing scientists how life might have evolved complex, multicellular forms. These rare bacteria canโt survive alone โ they depend on one a...
https://scitechdaily.com/these-tiny-magnetic-bacteria-act-like-a-single-body-and-could-explain-the-origins-of-complex-life/
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reposted by
Grainger Lab
MicrobesNG
8 months ago
We loved being back on campus for Master's hour on team working!
@unibirmingham.bsky.social
The students created content to highlight the excellent research from one of our customers! It's all about the Long Reads ๐
@graingerlab.bsky.social
@fozzz21.bsky.social
@imibirmingham.bsky.social
#MicroSky
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reposted by
Grainger Lab
Tom McLean
8 months ago
Super excited to share the peer-reviewed version of the KorAB paper. Amazing to work such talented collaborators and thanks to the reviewers for making the work even better!
www.nature.com/articles/s41...
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KorB switching from DNA-sliding clamp to repressor mediates long-range gene silencing in a multi-drug resistance plasmid - Nature Microbiology
Structural and single-molecule analyses show the CTPase, KorB, is a sliding DNA clamp that interacts with a clamp-locking protein KorA to inhibit gene expression over distances of more than 1โkb in th...
https://www.nature.com/articles/s41564-024-01915-3
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If you're interested in chromosome biology (DNA folding, gene regulation, replication, polymer modelling and more) we're organising the below this autumn. It'd be great to see you there. Please share if you can. :-)
8 months ago
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reposted by
Grainger Lab
Michael Brockhurst
10 months ago
2x professorships available in Manchester Institute of Biotechnology including in Microbial Engineering area (broadly defined to include microbiomes, environmental biotech etc) โ join us!
www.jobs.manchester.ac.uk/Job/JobDetai...
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Chair Appointments within Manchester Institute of Biotechnology:Manchester Institute of Biotechnology
https://www.jobs.manchester.ac.uk/Job/JobDetail?JobId=31012
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Grainger Lab
แฏIแTOแ แIแET, แฐแช
10 months ago
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PhD projects available in our lab all listed in the below link. All focus on bacterial gene regulation, in the context of basic understanding, disease, or antibiotic resistance. Deadlines in January...
www.findaphd.com/phds/?Keywor...
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grainger birmingham PhD Projects, Programmes & Scholarships
FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in grainger birmingham. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.
https://www.findaphd.com/phds/?Keywords=grainger+birmingham
10 months ago
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