Register now for on-demand access to @‌keystoneSymposia.bsky.social Immunometabolism Across Scales. The meeting explores the intersection of metabolism and immunity across biological scales, and their interplay in health and disease. ➡️ Find out more: plos.io/493x0zY #KSImmunometab26

Traditional behavioral models of bargaining interpret acceptance of #unfair offers as simple reward maximization. This study shows that #inequality aversion also shapes these decisions and identifies the #dACC as a regulator of responses to disadvantageous inequity @plosbiology.org 🧪 plos.io/4kmRadA

Does our very human ability to anticipate #musical structure exist at birth? @robertabianco.bsky.social @giacomonovembre.bsky.social &co show that #newborns encode #rhythmic (but not melodic) expectations based on statistical regularities in real #music @plosbiology.org plos.io/4kqKVWg

Traditional behavioral models of bargaining interpret acceptance of #unfair offers as simple reward maximization. This study shows that #inequality aversion also shapes these decisions and identifies the #dACC as a regulator of responses to disadvantageous inequity @plosbiology.org 🧪 plos.io/4kmRadA

Does our very human ability to anticipate #musical structure exist at birth? @robertabianco.bsky.social @giacomonovembre.bsky.social &co show that #newborns encode #rhythmic (but not melodic) expectations based on statistical regularities in real #music @plosbiology.org plos.io/4kqKVWg

I've joined the Editorial Board of @plosbiology.org PLOS Biology is the flagship #PLOS journal in the Life Sciences. I'm looking forward to handling terrific cell biology papers for them. #CellBiology

Clinical features of #BacterialVaginosis are well known, what are its underlying causes? This Primer explores a new ecological model in @plosbiology.org that provides a solid hypothesis corroborated by existing data, hinting at prophylactic strategies 🧪 Paper: plos.io/3NY2ssu Primer: plos.io/4tAj8a3

PLOS Biology is proud to present our new collection of comment and opinionated review articles on the many facets of #immunometabolism! 🧪 #immunosky #immunology #metabolism plos.io/4c5z6Cn See 🧵⬇️ for more details

Clinical features of #BacterialVaginosis are well known, what are its underlying causes? This Primer explores a new ecological model in @plosbiology.org that provides a solid hypothesis corroborated by existing data, hinting at prophylactic strategies 🧪 Paper: plos.io/3NY2ssu Primer: plos.io/4tAj8a3

HIV-1 induces #DNADamageResponse via Vpr, but does this affect the viral cycle? This study shows that Vpr-driven #DNA damage promotes epigenetic remodeling & transcriptional programs to enhance #HIV1 transcription & latency reactivation, with therapeutic potential @plosbiology.org 🧪 plos.io/4c9wVhe

The #vaginal #microbiome is shaped by bacterial access to specific nutritional resources. This study uses a resource-based model & clinical data to identify key ecological mechanisms underlying #microbiota composition & potential #BacterialVaginosis interventions @plosbiology.org 🧪 plos.io/3NY2ssu

Clinical features of #BacterialVaginosis are well known, what are its underlying causes? This Primer explores a new ecological model in @plosbiology.org that provides a solid hypothesis corroborated by existing data, hinting at prophylactic strategies 🧪 Paper: plos.io/3NY2ssu Primer: plos.io/4tAj8a3

HIV-1 induces #DNADamageResponse via Vpr, but does this affect the viral cycle? This study shows that Vpr-driven #DNA damage promotes epigenetic remodeling & transcriptional programs to enhance #HIV1 transcription & latency reactivation, with therapeutic potential @plosbiology.org 🧪 plos.io/4c9wVhe

The #vaginal #microbiome is shaped by bacterial access to specific nutritional resources. This study uses a resource-based model & clinical data to identify key ecological mechanisms underlying #microbiota composition & potential #BacterialVaginosis interventions @plosbiology.org 🧪 plos.io/3NY2ssu

There are clear sex differences in immunity, but we don't understand them well. Here Katie Flanagan and Sabra Klein discuss the state of the field and research priorities to advance our understanding and better prevent and treat disease in everyone @plosbiology.org #Immunosky 🧪

Our latest collection of commentary and Essays is devoted to #immunometabolism, highlighting how molecular & cellular mechanisms impact tissue and organismal functions, as well as the therapeutic potential of manipulating immunometabolism #cancer #aging #metabolism #inflammation 🧪 @plosbiology.org

HIV-1 induces #DNADamageResponse via Vpr, but does this affect the viral cycle? This study shows that Vpr-driven #DNA damage promotes epigenetic remodeling & transcriptional programs to enhance #HIV1 transcription & latency reactivation, with therapeutic potential @plosbiology.org 🧪 plos.io/4c9wVhe

The #vaginal #microbiome is shaped by bacterial access to specific nutritional resources. This study uses a resource-based model & clinical data to identify key ecological mechanisms underlying #microbiota composition & potential #BacterialVaginosis interventions @plosbiology.org 🧪 plos.io/3NY2ssu

#Azole resistance in #Candida albicans poses a growing threat, and is linked to #StressResponse. @annaselmecki.bsky.social &co show that mutations in the oxidative stress TF Cap1 promote #DrugResistance while exposing a lethal vulnerability at high azole doses @plosbiology.org 🧪 plos.io/4rOrfOz

#Azole resistance in #Candida albicans poses a growing threat, and is linked to #StressResponse. @annaselmecki.bsky.social &co show that mutations in the oxidative stress TF Cap1 promote #DrugResistance while exposing a lethal vulnerability at high azole doses @plosbiology.org 🧪 plos.io/4rOrfOz

Oviposition is crucial for #insect fitness and is a target for #PestControl. This study reveals that two #KainateReceptors in regulate #oviposition preference & egg-laying quantity in the fruit pest #Bactrocera dorsalis, and identifies relevant inhibitors @plosbiology.org 🧪 plos.io/4c6HgdK

#Azole resistance in #Candida albicans poses a growing threat, and is linked to #StressResponse. @annaselmecki.bsky.social &co show that mutations in the oxidative stress TF Cap1 promote #DrugResistance while exposing a lethal vulnerability at high azole doses @plosbiology.org 🧪 plos.io/4rOrfOz

Why are there such big differences between the sexes when it comes to immune responses? This Essay looks at what further research is required to fully determine sex-differential mechanisms in #immunity.🧪 #immunosky

Oviposition is crucial for #insect fitness and is a target for #PestControl. This study reveals that two #KainateReceptors in regulate #oviposition preference & egg-laying quantity in the fruit pest #Bactrocera dorsalis, and identifies relevant inhibitors @plosbiology.org 🧪 plos.io/4c6HgdK

#Antifungal resistance is a global threat, but epigenetic mechanisms drive rapid, reversible adaptation in fungi. This study shows that #RNAi or #heterochromatin driven #epimutations transiently silence the gene fkbA to confer FK506 #tacrolimus resistance in #Mucor @plosbiology.org 🧪 plos.io/4qdttWc

Unlike other #bacteria, C. difficile must detect both germinant & co-germinant signals to trigger #spore #germination. This study finds that the CspC:CspA complex is a key signaling node that integrates environmental cues to regulate #Cdifficile spore germination @plosbiology.org 🧪 plos.io/4rtCKdZ

Fungi can become drug-resistant without changing their DNA. They just... turn off the gene. And turn it back on when the drug's gone. This is wild and concerning for treating infections like mucormycosis (50-90% mortality). From Joe Heitman's group at @duke-university.bsky.social.

Why are there such big differences between the sexes when it comes to immune responses? This Essay looks at what further research is required to fully determine sex-differential mechanisms in #immunity.🧪 #immunosky

Oviposition is crucial for #insect fitness and is a target for #PestControl. This study reveals that two #KainateReceptors in regulate #oviposition preference & egg-laying quantity in the fruit pest #Bactrocera dorsalis, and identifies relevant inhibitors @plosbiology.org 🧪 plos.io/4c6HgdK

#Antifungal resistance is a global threat, but epigenetic mechanisms drive rapid, reversible adaptation in fungi. This study shows that #RNAi or #heterochromatin driven #epimutations transiently silence the gene fkbA to confer FK506 #tacrolimus resistance in #Mucor @plosbiology.org 🧪 plos.io/4qdttWc

Unlike other #bacteria, C. difficile must detect both germinant & co-germinant signals to trigger #spore #germination. This study finds that the CspC:CspA complex is a key signaling node that integrates environmental cues to regulate #Cdifficile spore germination @plosbiology.org 🧪 plos.io/4rtCKdZ

PLOS Biology is proud to present our new collection of comment and opinionated review articles on the many facets of #immunometabolism! 🧪 #immunosky #immunology #metabolism plos.io/4c5z6Cn See 🧵⬇️ for more details

Why are there such big differences between the sexes when it comes to immune responses? This Essay looks at what further research is required to fully determine sex-differential mechanisms in #immunity.🧪 #immunosky plos.io/4ro28S9

#Antifungal resistance is a global threat, but epigenetic mechanisms drive rapid, reversible adaptation in fungi. This study shows that #RNAi or #heterochromatin driven #epimutations transiently silence the gene fkbA to confer FK506 #tacrolimus resistance in #Mucor @plosbiology.org 🧪 plos.io/4qdttWc

Unlike other #bacteria, C. difficile must detect both germinant & co-germinant signals to trigger #spore #germination. This study finds that the CspC:CspA complex is a key signaling node that integrates environmental cues to regulate #Cdifficile spore germination @plosbiology.org 🧪 plos.io/4rtCKdZ

#Probiotics can influence neuronal health, but how does this happen? @aaballay.bsky.social &co show that #Enterococcus faecium activates an intestinal NHR-86/CYP450 pathway that lowers #ROS and protects #MotorNeurons, in a nematode model of #ALS @plosbiology.org 🧪 plos.io/3Mc0iVw

How does superficial white matter contribute to large-scale #brain function? @borismontreal.bsky.social &co use an approach based on 3D histology & 7-Tesla MRI to reveal associations between superficial #WhiteMatter microstructure & diverse cortical properties @plosbiology.org 🧪 plos.io/460WNIz

How are energy #metabolism pathways distributed across the #cortex? @alaindagher.bsky.social &co map five pathways in the human #brain, linking metabolic organization with brain structural & functional properties, as well as developmental dynamics @plosbiology.org 🧪 plos.io/4c1JVp8

Meet one of our editors at this unique @‌keystoneSymposia.bsky.social meeting exploring how immune signaling influences organ preservation, communication, and longevity. 🔗 plos.io/4a6Fln0 #KSAging26

#Probiotics can influence neuronal health, but how does this happen? @aaballay.bsky.social &co show that #Enterococcus faecium activates an intestinal NHR-86/CYP450 pathway that lowers #ROS and protects #MotorNeurons, in a nematode model of #ALS @plosbiology.org 🧪 plos.io/3Mc0iVw

How does superficial white matter contribute to large-scale #brain function? @borismontreal.bsky.social &co use an approach based on 3D histology & 7-Tesla MRI to reveal associations between superficial #WhiteMatter microstructure & diverse cortical properties @plosbiology.org 🧪 plos.io/460WNIz

How are energy #metabolism pathways distributed across the #cortex? @alaindagher.bsky.social &co map five pathways in the human #brain, linking metabolic organization with brain structural & functional properties, as well as developmental dynamics @plosbiology.org 🧪 plos.io/4c1JVp8

For #WorldWetlandsDay 2026, a selection of recent research in @plosone.org highlighting the diverse physical and biological roles of these important ecosystems. journals.plos.org/plosone/arti... journals.plos.org/plosone/arti... journals.plos.org/plosone/arti... journals.plos.org/plosone/arti...

#Probiotics can influence neuronal health, but how does this happen? @aaballay.bsky.social &co show that #Enterococcus faecium activates an intestinal NHR-86/CYP450 pathway that lowers #ROS and protects #MotorNeurons, in a nematode model of #ALS @plosbiology.org 🧪 plos.io/3Mc0iVw

How does superficial white matter contribute to large-scale #brain function? @borismontreal.bsky.social &co use an approach based on 3D histology & 7-Tesla MRI to reveal associations between superficial #WhiteMatter microstructure & diverse cortical properties @plosbiology.org 🧪 plos.io/460WNIz

How are energy #metabolism pathways distributed across the #cortex? @alaindagher.bsky.social &co map five pathways in the human #brain, linking metabolic organization with brain structural & functional properties, as well as developmental dynamics @plosbiology.org 🧪 plos.io/4c1JVp8

Sign up for ‘Biological oscillators: rhythms and synchronisation across scales’. This @‌events.embl.org Symposium will include topics on neuronal and cardiac dynamics, circadian and developmental rhythms, and oscillations in ecological and climate systems. Find out more ➡️ plos.io/46ozzvR #EESBioOsc

#Epithelialmechanics fans...interferons protect against viruses but also impair recovery post-infection. In new work @plosbiology.org we show that interferons block epithelial repair by co-opting the Hippo pathway #innateimmunity #lungs #respiratory journals.plos.org/plosbiology/...

Excited to join the Editorial Board of @plosbiology.org, the #PLOS flagship journal in the Life Sciences, that's blazing a trail in support of selective, equitable #OpenScience and reaching global audiences to help advance science faster 📝 🤓 🌱

#Cancer #immunotherapy faces widespread resistance via mechanisms like PD-L1 suppression. This study identifies the metabolic enzyme HSD17B12 as a regulator of PD-L1 degradation, showing that an HSD17B12-derived peptide boosts #AntiTumor #immunity in a mouse model @plosbiology.org 🧪 plos.io/4k2rtyR