Working link: journals.plos.org/plosbiology/...

Mammalian #muscle fiber contractions require voltage-gated #SodiumChannels. This study shows that #zebrafish fast muscle fibers don't require Nav channels, suggesting how anatomical & physiological differences from mouse muscles ensure efficient contraction @plosbiology.org 🧪 plos.io/49BMaOD

Internal states & #visual processing: Matteo Tripodi & @hirokiasari.bsky.social show that #histaminergic signaling from #hypothalamus modulates retinal & thalamic responses in mice, so low #histamine during idle periods may speed responses to visual threats @plosbiology.org 🧪 plos.io/49K0Qv8

Oxygen limitation is considered a key mechanism of #ThermalTolerance. @dianasmadeira.bsky.social explores how a @plosbiology.org study challenges this idea, showing minimal protective effects of O2 supersaturation in heat-stressed #aquatic #ectotherms 🧪 Paper: plos.io/43hzMQa Primer: plos.io/3XeUtbS

Mammalian #muscle fiber contractions require voltage-gated #SodiumChannels. This study shows that #zebrafish fast muscle fibers don't require Nav channels, suggesting how anatomical & physiological differences from mouse muscles ensure efficient contraction @plosbiology.org 🧪https://plos.io/49BMaOD

How do #PluripotentCells acquire lineage-specific identities during #GermLayer specification? This study shows that maternal TFs Foxi2 & Sox3 act as master regulators of ectodermal germ layer specification, ensuring robust & precise expression of target genes @plosbiology.org 🧪 plos.io/4nIUu2O

Very exciting to finally have this work out there. Thanks to the team at @plosbiology.org for being willing to publish null results!

Internal states & #visual processing: Matteo Tripodi & @hirokiasari.bsky.social show that #histaminergic signaling from #hypothalamus modulates retinal & thalamic responses in mice, so low #histamine during idle periods may speed responses to visual threats @plosbiology.org 🧪 plos.io/49K0Qv8

Mammalian #muscle fiber contractions require voltage-gated #SodiumChannels. This study shows that #zebrafish fast muscle fibers don't require Nav channels, suggesting how anatomical & physiological differences from mouse muscles ensure efficient contraction @plosbiology.org 🧪https://plos.io/49BMaOD

Oxygen limitation is considered a key mechanism of #ThermalTolerance. @dianasmadeira.bsky.social explores how a @plosbiology.org study challenges this idea, showing minimal protective effects of O2 supersaturation in heat-stressed #aquatic #ectotherms 🧪 Paper: plos.io/43hzMQa Primer: plos.io/3XeUtbS

Mammalian #muscle fiber contractions require voltage-gated #SodiumChannels. This study shows that #zebrafish fast muscle fibers don't require Nav channels, suggesting how anatomical & physiological differences from mouse muscles ensure efficient contraction @plosbiology.org 🧪https://plos.io/49BMaOD

Oxygen supersaturation is proposed to buffer against #HeatStress in water-breathing animals. @graham-raby.bsky.social @jutfelt.bsky.social &co re-examine this question in diverse #aquatic #ectotherms, showing that #hyperoxia has minimal impact on thermal tolerance @plosbiology.org 🧪 plos.io/43hzMQa

Oxygen limitation is considered a key mechanism of #ThermalTolerance. @dianasmadeira.bsky.social explores how a @plosbiology.org study challenges this idea, showing minimal protective effects of O2 supersaturation in heat-stressed #aquatic #ectotherms 🧪 Paper: plos.io/43hzMQa Primer: plos.io/3XeUtbS

Excited to announce our paper is out! Congrats to @pauformosa.bsky.social, @gweissbart.bsky.social, Frances Clark, and Xihang Wang on this fun and beautiful story. We answered a question about the randomness of giant cell spacing that I have had for at least 15 years.

Special thanks to @dianasmadeira.bsky.social for authoring this thoughtful primer about the study we published this week in @plosbiology.org Good suggestions about all the work we still need to do to unveil the mechanisms underlying variation in thermal tolerance. journals.plos.org/plosbiology/...

Oxygen supersaturation is proposed to buffer against #HeatStress in water-breathing animals. @graham-raby.bsky.social @jutfelt.bsky.social &co re-examine this question in diverse #aquatic #ectotherms, showing that #hyperoxia has minimal impact on thermal tolerance @plosbiology.org 🧪 plos.io/43hzMQa

PRMT5 is a #HistoneMethyltransferase upregulated in various cancer types. This study shows that PRMT5 regulates TCF3 #AlternativeSplicing under #hypoxia and that this promotes #EMT and invasion of #BreastCancer cells @plosbiology.org 🧪 plos.io/48ZbZrT

Oxygen supersaturation is proposed to buffer against #HeatStress in water-breathing animals. @graham-raby.bsky.social @jutfelt.bsky.social &co re-examine this question in diverse #aquatic #ectotherms, showing that #hyperoxia has minimal impact on thermal tolerance @plosbiology.org 🧪 plos.io/43hzMQa

PRMT5 is a #HistoneMethyltransferase upregulated in various cancer types. This study shows that PRMT5 regulates TCF3 #AlternativeSplicing under #hypoxia and that this promotes #EMT and invasion of #BreastCancer cells @plosbiology.org 🧪 plos.io/48ZbZrT

How are #plant #leaf epidermal cells patterned? @roederlab.bsky.social &co show that the pathway controlling #GiantCell formation in #sepals also controls cell size in #Arabidopsis leaves, via cell-autonomous & stochastic specification @plosbiology.org 🧪 plos.io/491F1qQ

The superior colliculus acts as a biological radar: it receives direct retinal input and, before information reaches cortex, selects the most relevant stimuli. When something moves, flashes or appears, it is the first to respond and orient our gaze. 📷Peng Cui @plosbiology.org

Oxygen supersaturation has been reported to protect aquatic animals from heat waves. We tested this in a large collaborative experiment on many species of fish and crustaceans. Our new paper in @plosbiology.org shows that the effect of hyperoxia on thermal tolerance is negligible. Unfortunately.

PRMT5 is a #HistoneMethyltransferase upregulated in various cancer types. This study shows that PRMT5 regulates TCF3 #AlternativeSplicing under #hypoxia and that this promotes #EMT and invasion of #BreastCancer cells @plosbiology.org 🧪 plos.io/48ZbZrT

How are #plant #leaf epidermal cells patterned? @roederlab.bsky.social &co show that the pathway controlling #GiantCell formation in #sepals also controls cell size in #Arabidopsis leaves, via cell-autonomous & stochastic specification @plosbiology.org 🧪 plos.io/491F1qQ

#Haplodiploid inheritance is found in all species of #Hymenoptera. @mwbstr.bsky.social &co map the #sex determining #gene of the red mason #bee to the ANTSR gene region, suggesting a shared, ancient origin of #SexDetermination in bees & ants >150 Mya ago @plosbiology.org 🧪 plos.io/47COEtH

#Evolution of complex adaptations can involve changes in multiple traits that lack standalone function. @benitoexplains.bsky.social &co show that leaf masquerade in #katydids evolved via concurrent modification in wing colour & shape, driven by evolutionary synergy @plosbiology.org 🧪 plos.io/4oUE741

How are #plant #leaf epidermal cells patterned? @roederlab.bsky.social &co show that the pathway controlling #GiantCell formation in #sepals also controls cell size in #Arabidopsis leaves, via cell-autonomous & stochastic specification @plosbiology.org 🧪 plos.io/491F1qQ

Leaf? 🍃 Or katydid? 🦗 Our new @plosbiology.org paper sheds light on how these incredible mimics evolved their disguises, and what this reveals about how complex adaptations arise. We find that coordinated evolution between traits might be the answer… plos.io/4oUE741 1/n

Latest research from the lab where we mapped the sex-determining gene in the red mason bee. Surprisingly it turned out to be the same gene used by ants, suggesting an ancient origin >150 million years ago. Thanks to the many people involved!

#Haplodiploid inheritance is found in all species of #Hymenoptera. @mwbstr.bsky.social &co map the #sex determining #gene of the red mason #bee to the ANTSR gene region, suggesting a shared, ancient origin of #SexDetermination in bees & ants >150 Mya ago @plosbiology.org 🧪 plos.io/47COEtH

#Evolution of complex adaptations can involve changes in multiple traits that lack standalone function. @benitoexplains.bsky.social &co show that leaf masquerade in #katydids evolved via concurrent modification in wing colour & shape, driven by evolutionary synergy @plosbiology.org 🧪 plos.io/4oUE741

#Haplodiploid inheritance is found in all species of #Hymenoptera. @mwbstr.bsky.social &co map the #sex determining #gene of the red mason #bee to the ANTSR gene region, suggesting a shared, ancient origin of #SexDetermination in bees & ants >150 Mya ago @plosbiology.org 🧪 plos.io/47COEtH

#Evolution of complex adaptations can involve changes in multiple traits that lack standalone function. @benitoexplains.bsky.social &co show that leaf masquerade in #katydids evolved via concurrent modification in wing colour & shape, driven by evolutionary synergy @plosbiology.org 🧪 plos.io/4oUE741

Scientists still have a very limited understanding of #marine #biodiversity. Jonathan Belmaker explores a new @plosbiology.org study that uses unprecedented global environmental DNA #eDNA sampling to reveal the extent of our ignorance 🧪 Paper: plos.io/47yRnEk Primer: plos.io/3XeJ2kl

Scientists still have a very limited understanding of #marine #biodiversity. Jonathan Belmaker explores a new @plosbiology.org study that uses unprecedented global environmental DNA #eDNA sampling to reveal the extent of our ignorance 🧪 Paper: plos.io/47yRnEk Primer: plos.io/3XeJ2kl

Big New! @elife.bsky.social @genetics-gsa.bsky.social #G3journal are joining editorial forces with @reviewcommons.org - bringing not just field-specific expertise to the process but also making #PreprintPeerReview a truly collaborative effort!🎉👏 Read more to find out👇 www.embo.org/features/pub...

Scientists still have a very limited understanding of #marine #biodiversity. Jonathan Belmaker explores a new @plosbiology.org study that uses unprecedented global environmental DNA #eDNA sampling to reveal the extent of our ignorance 🧪 Paper: plos.io/47yRnEk Primer: plos.io/3XeJ2kl

Q: What do 40% of papers on animal stroke experiments have in common? A: Fake data. So found a study published Thursday in @plosbiology.org journals.plos.org/plosbiology/... 🧪 #ResearchIntegrity #SciComment

Incomplete characterization and inconsistent reporting of laboratory animal #genetics undermine study quality and limit research #reproducibility. @reproducibilityexp.bsky.social highlight the LAG-R guidelines and call for collective action to enhance scientific integrity.🧪

Incomplete characterization and inconsistent reporting of laboratory animal #genetics undermine study quality and limit research #reproducibility. @reproducibilityexp.bsky.social highlight the LAG-R guidelines and call for collective action to enhance scientific integrity.🧪

Erroneous articles can undermine scientific progress & mislead research. @deadneanderthals.bsky.social &co show that 40% of articles on #BrainInjury in animal studies have #ImageDuplication & #ImageManipulation problems, but correction by #journals remains limited @plosbiology.org 🧪 plos.io/4p59QzN

Global species records often underestimate marine #fish distributions. @loic-patanegra-scz.bsky.social &co show that #eDNA surveys significantly expand known geographic & ecological niche ranges, revealing hidden #biodiversity & improving predictions @plosbiology.org 🧪 plos.io/47yRnEk

Incomplete characterization and inconsistent reporting of laboratory animal #genetics undermine study quality and limit research #reproducibility. @reproducibilityexp.bsky.social highlight the LAG-R guidelines and call for collective action to enhance scientific integrity.

Global species records often underestimate marine #fish distributions. @loic-patanegra-scz.bsky.social &co show that #eDNA surveys significantly expand known geographic & ecological niche ranges, revealing hidden #biodiversity & improving predictions @plosbiology.org 🧪 plos.io/47yRnEk

Erroneous articles can undermine scientific progress & mislead research. @deadneanderthals.bsky.social &co show that 40% of articles on #BrainInjury in animal studies have #ImageDuplication & #ImageManipulation problems, but correction by #journals remains limited @plosbiology.org 🧪 plos.io/4p59QzN

Our new paper is out in PLOS Biology! I'm very conflicted about the project: proud because it feels like the most important project I've ever been a part of, but also very sad that we found so many problems in our field. Read the paper here: journals.plos.org/plosbiology/...

Global species records often underestimate marine #fish distributions. @loic-patanegra-scz.bsky.social &co show that #eDNA surveys significantly expand known geographic & ecological niche ranges, revealing hidden #biodiversity & improving predictions @plosbiology.org 🧪 plos.io/47yRnEk

How prevalent is #ImageManipulation in biomedical science? This paper in @plosbiology.org shows that in a random-ish subfield (animal studies of stroke) a staggering 40% (!) of papers had image duplication and/or manipulation... and journals were slow to correct journals.plos.org/plosbiology/...

Erroneous articles can undermine scientific progress & mislead future research. Rene Aquarius &co show that 40% of articles on early #BrainInjury in animal studies have #ImageDuplication & #ImageManipulation problems, but correction by #journals remains limited @plosbiology.org 🧪 plos.io/4p59QzN