During task performance, the brain must integrate information re goal-related objects with contextual details. This study shows that participants' performance on a #SpatialNavigation task is related to syncing of activity between #hippocampus & #EntorhinalCortex @plosbiology.org 🧪 plos.io/3Vrw8id

During task performance, the brain must integrate information re goal-related objects with contextual details. This study shows that participants' performance on a #SpatialNavigation task is related to syncing of activity between #hippocampus & #EntorhinalCortex @plosbiology.org 🧪 plos.io/3Vrw8id

#Macrophage polarization involves distinct phases of regulation. This study shows that upstream translation & AU-rich codon usage enhance #mRNA stability & #translation efficiency, enabling dynamic control of immune activation during #inflammatory stimulation @plosbiology.org 🧪 plos.io/422aFA7

During task performance, the brain must integrate information re goal-related objects with contextual details. This study shows that participants' performance on a #SpatialNavigation task is related to syncing of activity between #hippocampus & #EntorhinalCortex @plosbiology.org 🧪 plos.io/3Vrw8id

#Macrophage polarization involves distinct phases of regulation. This study shows that upstream translation & AU-rich codon usage enhance #mRNA stability & #translation efficiency, enabling dynamic control of immune activation during #inflammatory stimulation @plosbiology.org 🧪 plos.io/422aFA7

Despite recent advances in green genetically encoded #potassium indicators (GEPOs), red-shifted GEPOs have been slower to come. @piatkevich.bsky.social &co present 2 new red #fluorescent #indicators for visualizing neuronal K+ dynamics in culture & in mice @plosbiology.org 🧪 plos.io/42niaSz

Cortical development in #primates follows a hierarchical gradient, but how does this vary between species? This study shows that #humans & #macaques share conserved maturation patterns, with humans exhibiting prolonged #cortical development @plosbiology.org 🧪 plos.io/4prEO65

If you are from the US and interested in applying for a PhD with me (or anyone else @camzoology.bsky.social @cambridgebiosci.bsky.social), your deadline for the gates scholarship is October 15! (You’ll need to write a research proposal, so contact PIs now) www.gatescambridge.org/programme/th...

#Macrophage polarization involves distinct phases of regulation. This study shows that upstream translation & AU-rich codon usage enhance #mRNA stability & #translation efficiency, enabling dynamic control of immune activation during #inflammatory stimulation @plosbiology.org 🧪 plos.io/422aFA7

Despite recent advances in green genetically encoded #potassium indicators (GEPOs), red-shifted GEPOs have been slower to come. @piatkevich.bsky.social &co present 2 new red #fluorescent #indicators for visualizing neuronal K+ dynamics in culture & in mice @plosbiology.org 🧪 plos.io/42niaSz

This Primer explores two @plosbiology.org studies that reveal how short axon cells in the #OlfactoryBulb integrate #cholinergic input from the basal #forebrain to dynamically regulate #olfactory input 🧪Papers: plos.io/4pvost3 plos.io/3VnO1hT Primer: plos.io/3Ivzcqy

How do your #linguistic, #economic & #gender backgrounds impact your #scientific productivity? @tatsuya-amano.bsky.social & co reveal that being a woman, a non-native English speaker, and from a low-income country is associated with a 70% reduction in productivity @plosbiology.org 🧪 plos.io/4n3RLRQ

Cortical development in #primates follows a hierarchical gradient, but how does this vary between species? This study shows that #humans & #macaques share conserved maturation patterns, with humans exhibiting prolonged #cortical development @plosbiology.org 🧪 plos.io/4prEO65

With the caveat productivity is defined as the number of papers published, it's notable to see that the gender and English proficiency gaps are about the same overall. Then the gender gap decreases along the career, while the English proficiency gap widens

🌱From Bud to Branch🌱 New model reveals how local & systemic signals combine to regulate shoot branching. "...by modulating #auxin transport, local #BRC1 expression in each bud could contribute to the systemic control of branching." @zoenahas.bsky.social 🔗 dx.plos.org/10.1371/jour... @plosbiology.org

Cortical development in #primates follows a hierarchical gradient, but how does this vary between species? This study shows that #humans & #macaques share conserved maturation patterns, with humans exhibiting prolonged #cortical development @plosbiology.org 🧪 plos.io/4prEO65

This Primer explores two @plosbiology.org studies that reveal how short axon cells in the #OlfactoryBulb integrate #cholinergic input from the basal #forebrain to dynamically regulate #olfactory input 🧪Papers: plos.io/4pvost3 plos.io/3VnO1hT Primer: plos.io/3Ivzcqy

How do your #linguistic, #economic & #gender backgrounds impact your #scientific productivity? @tatsuya-amano.bsky.social & co reveal that being a woman, a non-native English speaker, and from a low-income country is associated with a 70% reduction in productivity @plosbiology.org 🧪 plos.io/4n3RLRQ

Despite recent advances in green genetically encoded #potassium indicators (GEPOs), red-shifted GEPOs have been slower to come. @piatkevich.bsky.social &co present 2 new red #fluorescent #indicators for visualizing neuronal K+ dynamics in culture & in mice @plosbiology.org 🧪 plos.io/42niaSz

This Primer explores two @plosbiology.org studies that reveal how short axon cells in the #OlfactoryBulb integrate #cholinergic input from the basal #forebrain to dynamically regulate #olfactory input 🧪Papers: plos.io/4pvost3 plos.io/3VnO1hT Primer: plos.io/3Ivzcqy

How do your #linguistic, #economic & #gender backgrounds impact your #scientific productivity? @tatsuya-amano.bsky.social & co reveal that being a woman, a non-native English speaker, and from a low-income country is associated with a 70% reduction in productivity @plosbiology.org 🧪 plos.io/4n3RLRQ

VPS13A & VPS13C are lipid transport proteins linked to #ChoreaAcanthocytosis & #ParkinsonsDisease. @pengxu.bsky.social @pdc-lab.bsky.social &co shows that mice lacking either protein are viable but absence of both results in defective #hematopoiesis & lethality @plosbiology.org 🧪 plos.io/46rTEAy

#DiscriminativeLearning enhances #sensory contrast for rapid, accurate decisions, but how? This study describes a sensory- #forebrain circuit centered on #dopaminergic short axon cells in the mouse #olfactory bulb, which refines sensory input during learning @plosbiology.org 🧪 plos.io/4pvost3

Animals can use cues to initiate task preparation and amplify relevant #sensory input, but how? This study describes a circuit whereby an attentional cue triggers #cholinergic #forebrain activity, enhancing #olfactory responses (deactivated upon task-proficiency) @plosbiology.org 🧪 plos.io/3VnO1hT

Individual variation in #sociability is a central feature of every society, including #HoneyBees. This study shows that specific genetic variants & #brain gene expression patterns are linked to variation in the social act of sharing liquids (trophallaxis) in bees @plosbiology.org 🧪 plos.io/3VjjXnJ

‬‬Hexokinase 2 (HK2) is known for its metabolic role in #glycolysis. This study shows that it also functions as an #RNAbindingProtein that regulates mRNA translation, particularly of SOX10, promoting #melanoma cell proliferation independently of glycolysis @plosbiology.org 🧪 plos.io/3ViI1qL

The rise of AI is reshaping how we think, write, and review science. This #PeerReviewWeek, we’re asking how do we preserve trust and transparency in a system that’s rapidly evolving? 🔗 Read our latest blog: plos.io/46d8BI9 @peerreviewweek.bsky.social #OpenScience #PRW2025

VPS13A & VPS13C are lipid transport proteins linked to #ChoreaAcanthocytosis & #ParkinsonsDisease. @pengxu.bsky.social @pdc-lab.bsky.social &co shows that mice lacking either protein are viable but absence of both results in defective #hematopoiesis & lethality @plosbiology.org 🧪 plos.io/46rTEAy

#DiscriminativeLearning enhances #sensory contrast for rapid, accurate decisions, but how? This study describes a sensory- #forebrain circuit centered on #dopaminergic short axon cells in the mouse #olfactory bulb, which refines sensory input during learning @plosbiology.org 🧪 plos.io/4pvost3

Animals can use cues to initiate task preparation and amplify relevant #sensory input, but how? This study describes a circuit whereby an attentional cue triggers #cholinergic #forebrain activity, enhancing #olfactory responses (deactivated upon task-proficiency) @plosbiology.org 🧪 plos.io/3VnO1hT

We have submitted a response to the National Institutes of Health's Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs. We believe that equitable access to publishing is essential to advancing open science. 🔗 Read our full response here: plos.io/4n9MEzF

VPS13A & VPS13C are lipid transport proteins linked to #ChoreaAcanthocytosis & #ParkinsonsDisease. @pengxu.bsky.social @pdc-lab.bsky.social &co shows that mice lacking either protein are viable but absence of both results in defective #hematopoiesis & lethality @plosbiology.org 🧪 plos.io/46rTEAy

#DiscriminativeLearning enhances #sensory contrast for rapid, accurate decisions, but how? This study describes a sensory- #forebrain circuit centered on #dopaminergic short axon cells in the mouse #olfactory bulb, which refines sensory input during learning @plosbiology.org 🧪 plos.io/4pvost3

Animals can use cues to initiate task preparation and amplify relevant #sensory input, but how? This study describes a circuit whereby an attentional cue triggers #cholinergic #forebrain activity, enhancing #olfactory responses (deactivated upon task-proficiency) @plosbiology.org 🧪 plos.io/3VnO1hT

Individual variation in #sociability is a central feature of every society, including #HoneyBees. This study shows that specific genetic variants & #brain gene expression patterns are linked to variation in the social act of sharing liquids (trophallaxis) in bees @plosbiology.org 🧪 plos.io/3VjjXnJ

‬‬Hexokinase 2 (HK2) is known for its metabolic role in #glycolysis. This study shows that it also functions as an #RNAbindingProtein that regulates mRNA translation, particularly of SOX10, promoting #melanoma cell proliferation independently of glycolysis @plosbiology.org 🧪 plos.io/3ViI1qL

Curious about new developments in imaging methods? This @embl.org symposium will explore topics on tissue and intravital imaging, AI, image data and modelling, new applications of imaging technologies, and more. Virtual registration is open until October 1. Learn more at plos.io/472r0YR

The ear's organ of Corti as a model system of how developmental instructions coordinate across spatial scales so that tissues are sculpted reproducibly 📷 @prakash-patterns.bsky.social et al @tifr.res.in in @plosbiology.org ➡️ bpod.org.uk/archive/2025...

Codex made my #software ~3.5x faster per #FASTA entry!💥 Previous version 🔵. #Codex optimized in 🟠 Beyond my use case, this suggests that tools like Codex can be used to solve a major issue in #bioinformatics — the long-term stability of software🛠️, which threatens scientific reproducibility.

Original publication here: journals.plos.org/plosbiology/... Many thanks to @roliroberts.bsky.social for their professional handling of the manuscript

Individual variation in #sociability is a central feature of every society, including #HoneyBees. This study shows that specific genetic variants & #brain gene expression patterns are linked to variation in the social act of sharing liquids (trophallaxis) in bees @plosbiology.org 🧪 plos.io/3VjjXnJ

Hexokinase 2 (HK2) is known for its metabolic role in #glycolysis. This study shows that it also functions as an #RNAbindingProtein that regulates mRNA translation, particularly of SOX10, promoting #melanoma cell proliferation independently of glycolysis @plosbiology.org 🧪 plos.io/3ViI1qL

🚨 New paper alert! 🚨 Our paper entitled: "Neuron-specific Agrin splicing by Nova RNA-binding proteins regulates conserved neuromuscular junction development in chordates" is out now on @plosbiology.org ! journals.plos.org/plosbiology/... #splicing #microexons #NMJ #Ciona 🧵👇

How do #plants dynamically modulate their shoot branching for optimal returns? ‪@zoenahas.bsky.social‬ &co show that BRC1 modulates bud competitiveness by reducing #auxin efflux, integrating hormonal cues to fine-tune branching patterns @plosbiology.org @slcuplants.bsky.social 🧪 plos.io/4pnrwY2

This year’s #PeerReviewWeek theme “Rethinking Peer Review in the AI Era” asks how tech is reshaping research. PLOS CEO, Alison Mudditt, shares her take on AI, open science, and the future of research integrity in this interview with @authorsalliance.bsky.social. 📖 plos.io/3K9UXwF

In a newly released arXiv preprint, we explore how open science practice like sharing data, code and preprints relate to citation impact in French-authored research over a 3-year period. Thanks to @ouvrirlascience.bsky.social for highlighting its national importance. 🔗 Read more: plos.io/3Vmykrj

Post-transcriptional #GeneRegulation through #m6A deposition is dysregulated in many diseases. Samie Jaffrey &co investigate why the m6A writer complex requires multiple subunits and what roles its individual proteins might have in m6A regulation. 🧪 plos.io/3VjfjWI

In today's ROR Community Call, we'll hear about technical updates to ROR and will hear about ROR and publishing platform @atypon.bsky.social. There's still time to register! ror.org/events/#ror-...

How do #plants dynamically modulate their shoot branching for optimal returns? ‪@zoenahas.bsky.social‬ &co show that BRC1 modulates bud competitiveness by reducing #auxin efflux, integrating hormonal cues to fine-tune branching patterns @plosbiology.org @slcuplants.bsky.social 🧪 plos.io/4pnrwY2