I don't think anybody has described the value of open source in the way Andrew Huang has, that essentially its to demystify the prestige around knowledge that comes with labels and preconceptions on how hard something is supposed to be www.youtube.com/watch?v=aFrT...

I am very glad to see that our PolarSIM helps the leading scientists to observe richer dynamics and get more discovery! Congratulations to Zhixing team for this brand new palette of fluorescent dyes named after BeiDa! www.nature.com/articles/s41... @pku1898.bsky.social @zhixingchen2.bsky.social

🚨 New preprint alert! We used IntAct + Ultrastructure Expansion microscopy to map actin isoforms in 3D🤯 Check out this gorgeous 3D volume of U2OS cells - revealing diverse filament networks including the elusive nuclear actin filaments! #cytoskeleton #microscopy #actin

You did it @syncellbiolab.bsky.social !! Amazing . Congrats to the Team and what gorgeous imaging ... Wow

Lovely work from Saravanan and colleagues, they insert the 13aa alfa tag into actin and then use an Alexa-nanobody to monitor actin in expansion microscopy in yeast and human cells. This is an excellent tool for actin research, and the general principle can be applied to a variety of other proteins.

Beautiful images 🤩

1, 2, 3, 4. "Electronic lab notebooks, despite their popularity, are stored in proprietary formats, incur a recurrent cost, tend to become defunct over time, and have poor interoperability with each other" journals.plos.org/plosbiology/...