Running through my New Year's activities for the office. Printed out a cute little writing accountability tracker. This is for me to track whether I do my 30 minutes of writing per day, this is a New Year's resolution new this year.

Proximity labeling users: check out this study by @zhixingchen2.bsky.social and Peng Zou, which establishes how much contact-dependence vs. diffusion is responsible for biotinylation — tl;dr TurboID has a much smaller effective radius! www.nature.com/articles/s41... 1/2

I'm a New Year's resolution person. It's a way to try out new habits; sometimes they work, sometimes they don't. I'm ok with it not working, but I want to give it my best shot. This year, I want to start a morning writing routine for work-related writing. I'm looking for advice and inspiration.

A story in two images. Courtesy of my sister.

We made a resource to help with that: "When goodbye comes too soon: How to wrap up science projects quickly" journals.plos.org/plosbiology/...

Our wonderful technician Xiaolin (Lin) Zhu is retiring after 27 years of dedicated service in our lab. We will miss her greatly, but we are happy for her as she begins this well-deserved new chapter in her life.

Though I do paid work as an academic, that role has nothing to do with plants. This project definitely could be published as a research paper (especially once I produce blue versions of runner beans or lima beans), but that is only likely if some lab decides to collaborate with me on it.

Anyone running a genomic CURE want to collaborate with Dr Abbey to sequence blue beans?

One of my most favorite gifts of all times, believe it or not, was a red leather bookmark from Norwich with different landmarks printed on it in gold leaf and a fringe bottom. I was just a kid. It smelled ancient for some reason, and was soft and pleasing to keep in the hand when reading.

Yay! crispr worked!! We have gfp tagged cell lines just in time for 2026!!

My sister in law gives the best gifts. Last time I visited she gave me this set of paintable cards. It’s so much fun and addictive. I’m probably going to do the whole box this break.

In the Pacific Northwest? Want to help farmers operate more efficiently? Have experience in agricultural sales or related areas? Looking for a new job? Harvest Source is a new agriculture supply company, and they are looking for you! harvest-source.com/jobs

How are people dealing with AI use in their grad programs, specifically for thesis proposal, qualifying exam, dissertation? Banned completely? Allowed, but have to recognize its use? No guardrails at all? We have to develop a policy and I’m totally at a loss.

Just decline the peer review invitation. What are you people even doing?

I ***love*** suppressor genetics. This is a great example.

A reminder to use the right P2A sequence to produce separate proteins - the images are from a GPCR-P2A-mCherry construct using a P2A variant without (upper row) and with (lower row) a preceding GSG linker.

This is your annual reminder that if you are in the US and have FSA funds that you won't use, Menstrual products are covered by FSA funds and can be donated to food pantries and shelters.

Field botanist job with Virginia Natural Heritage, based in Roanoke, VA. $55-65K pay range. Please share widely! www.jobs.virginia.gov/jobs/field-b...

Calling all #YeastResearch -ers! Who would like to work in beautiful Barcelona? 🌴🌊 And even better, work on #cerevisiae? #ScienceJobs #EarlyScienceCareer #ResearchOpportunities #STEMCareers #CareerInScience #Yeast

@ascbiology.bsky.social 's Women in Cell Biology (WICB) has yet another fantastic event today at 4pm, room 126A. A networking panel on "Thriving in Uncertain Times: Navigating Career and Funding Challenges". #cellbio2025.

So happy to be making my return to @ascbiology.bsky.social CellBio after attending as an undergrad in 2019. It’s been an amazing conference and I’ve loved learning about all the different nuclear biology research being done!

Our Lab @ NCBS, Bangalore is hiring PhD students! If you’re excited about cell & developmental biology, tissue mechanics, and imaging — come join us! We use C. elegans to uncover how forces shape organs 🧫🔬 CSIR/DBT/ICMR fellowship holders encouraged to apply!Apply 👉 lnkd.in/gr9EUHnp

ASCB President Mary Munson awards Francis Collins the ASCB Public Service award, noting this is the first time it’s been awarded for defense of science #cellbio2025

"Yet whoever has a great deal of internal warmth of his own will prefer to keep away from society in order to avoid giving or receiving trouble or annoyance." My blessing to you: May you all have the shared warmth you need, with a minimum number of pricks in your life.

And blew this cell biologist’s mind with real-life, practical advice on how to promote scientific literacy, curiosity, and critical thinking! At the Special President’s Session #CellBio2025 Thank you, @galesinatra.bsky.social!

Meeting in Roundtables Section, Exhibit Hall D on Monday, Dec 8 12:00 to 12:45 PM

Bummed to miss #ASCB this year (one of my fav meetings), but the lab is well represented! Stop by poster B169 today and Maneesha will tell you all about her work on basal bodies and cilia homeostasis in multiciliated cells 👇 #CellBio2025

Bummed not to be at ASCB/CellBio this year. Was really looking forward to some cheesesteaks. And if course the science. Great meeting to really discuss the projects of many of my grantees.

Packed room for the opening mentoring keynote by Maggie Werner Washburne talking about the importance of imagination in science and persistence #CellBio2025

🧪 Hi protein interaction researchers, Quick question. When doing a bead binding assay, do you pre clear lysates with beads lacking the appropriate epitope prior to adding the affinity beads? I did this when we used to used inactivated staph rather than sepharose, but never with sepharose.

Science is under attack and your support can help budding young scientists from the undergraduate levels throughout their careers. I would not be here today if it's not for the community I have found at the ASCB

Yeah, I think so. I think the assumption is that "You can contact me with questions" is code for "I don't dare put the truth down in print, phone me and I'll tell you the real deal about how bad this person is." Found the article! doi.org/10.1006/jsre...

Flying solo for bioimqge analysis is hard! You have to balance a lot of considerations. I’ve become a big fan of the Z’/SSMD pre-test, used more often in high content screening. Run a positive control first to see if the processing and stats protocols are matched to the expt needs.

Spending real time together at the white board with the group can create a supportive training environment, where the peer group can lean on each other as they are speaking a common language. Perhaps practice the strategies of including all the appropriate controls and draw what would be expected?

***Important*** BIO will host a Virtual Office Hour (VOH) on Thurs, Dec 18th, 2025, 1 - 2 pm ET. In this VOH, we’ll be joined by leadership to outline updates to NSF’s review process & share news relevant to all areas of research funded by BIO. Register here: nsf.zoomgov.com/webinar/regi...

🧪I frequently have inexperienced trainees applying a quantitative image analysis pipeline without actually looking at the images to ensure it is valid for the samples. Case in point: quantifying puncta intensity to monitor protein delocalization.

Are you interested in cytoskeleton and looking for a postdoc position? I will be advertising positions in the new year but happy to chat in person if you are attending ASCB @ascbiology.bsky.social in Philadelphia. Just drop me a line.

Super excited for the upcoming #cellbio2025 @ascbiology.bsky.social @embo.org meeting in Philadelphia! Check out the Special President's session on "The Rising Tide of Science Denial" on Saturday at 1pm!

#membrane seminars are back this THURSDAY for a super session with @dr-downes.bsky.social from the @giuliazanetti.bsky.social lab and Xin Zhou from the Ikonen lab! @felixmendu.bsky.social @ishier.bsky.social

New paper is out! A super fun collab with @akw-lab.bsky.social We started with a pilot grant from UW Nathan Shock Center, ended up describing how different S-adenosylmethionine synthases (sams) have distinct functional roles

Heading into finals? Almost done!! Yay! I'm sure you've learned so much! I hope your classes went well. But even if they didn’t I’m sure you learned a lot. Maybe you learned some study skills for next year. Maybe you learned to identify when you are overwhelmed.

Hey, I just met you... And this is crazy... Do me a favor??? Review this paper?

I'm teaching a literature based class next semester and plan to share a method for reading a paper focused on note taking. I think many graduate students don't take notes when reading research articles and consequently don't retain information well. I'd love to hear what people think. 1/🧵

Question to y'all #protein experts: we used to do limited proteolysis, then N-terminal sequencing to see where domains are in proteins. no more N-terminal sequencing. 1) why doesnt anyone do Edman any more? 2) what is the most accurate / feasible / cost effective way to do this now?

I am very excited to announce that a fully funded PhD position is available in my group. Topic: Synergistic coevolution in mono-specific and multi-species microbial consortia Please RT or forward this information to interested candidates. Deadline: 11.01.26 More info: shorturl.at/f1TuF

Hi Bluesky! I’m a molecular virologist studying how innate immune defences restrict cross-species transmission and shape disease severity. I just joined, so reposts appreciated to help me reconnect with virology, immunology, and host–pathogen interaction folks. (whiteboard art from Zhuonan Li)

DECRAs are out! Good luck young investigators. If you are unlucky- please don't let this moment define you. #ARC

I am looking for a PostDoc to join my group at Genentech to drive the development of proteomics technologies to fuel target and therapeutic discovery and development. Check out the link below! careers.gene.com/us/en/job/20...

🎓 Grad School Interviews: DOs & DON’Ts⁠ ⁠ Getting ready for your graduate school interviews? Join us for a session where we break down what to say, how to prepare, and how to show up as your most authentic self.⁠ ⁠ 🗓 When: December 2nd at 10am ET⁠ 🔗 Register here: www.eventbrite.com/e/grad-schoo...

Open faculty position (Assistant or Associate) in UW Medical Genetics. As you might expect, faculty often end up also interacting with Genome Sciences, so we're hoping for some great prospects! Note the clinical requirements for the position. apply.interfolio.com/176466