Great to see this paper with @elainetao.bsky.social out in print at the Biophysical Journal. Using Alphafold to study conformational transitions in 32 voltage-gated channel superfamily members #ionchannel #AI #StructuralBiology www.sciencedirect.com/science/arti...

📣 Save the date for the 51st Lorne Conference on Protein Structure and Function! ✨ Lorne, Victoria, Australia. We have a packed program and we'll be sharing all the details here - Like, Follow and Share - because friends don't let friends miss the epic Lorne Proteins 😊 www.lorneproteins.org

2 yrs ago @yiechanglin.bsky.social sent me this movie of lipid scrambling by OSCA1.2. Now we show it’s common to WT OSCA/TMEM63 proteins, mechanically activated, cholesterol dependent, and protects cells from damaging forces. Awesome collab with @charlesdcox.bsky.social &Zhang lab. tiny.cc/tmem63

Applications for this position are closing tomorrow! Get yours in quickly 😁

🌟 We are hiring! Seeking a postdoc to use molecular dynamics and AI to understand how ion channels are regulated by membrane lipids 🌟 Join us at #scienceanu with amazing collaborators and great working conditions! Email me (karri.anu.edu.au) or apply here (tiny.cc/corry). Please share & repost!

Excited to share John's new work in Nat Coms! We demonstrate how PfCRT, a polyspecific peptide transporter, turns into a drug transporter for antimalarials like chloroquine and why this causes a fitness cost for the malaria parasite (1/2) tiny.cc/PfCRT

Also bittersweet to announce the final work of @elainetao.bsky.social in our lab, using AF2 to study conformational transitions in 32 voltage-gated channel superfamily members 🤩 we're so excited to watch you Nav-igate the next steps of your career, Dr. Tao & are so proud of you 🎩 tiny.cc/VSD-AF2

Bittersweet to announce the wonderful YC's final work in our lab. We are so proud of everything she's accomplished (incl. this beautiful study showing how the TAM complex facilitates lipid flow between the bacterial inner & outer membranes). We can't wait to see what you do next, Dr. Lin 🤩

Thrilled to share our latest preprint from @yiechanglin.bsky.social & @ciarawallis.bsky.social showing that AF2-Multimer and AF3 can quickly & accurately predict the oligomeric states & structures of proteins (& maybe can identify multiple biologically relevant oligomeric states 👀) tiny.cc/oligomers

Big congratulations to the very sharp @elainetao.bsky.social who submitted her PhD last week! Our greatest Nav channel expert is rumoured to be joining the dark side of Kv. #drtao #phdone @scienceanu.bsky.social 🔪🎆👩‍🔬👩‍🎓

Anders ECR session Ruitao Jin: plant Ca ion channels. Mechanical gating of OSCA channels. 100s of subtypes sense and react to physical forces. Homodimers with protomer pore and cleft. Liposome inside-in structure. Membrane belt-MD avg position of lipid head group. Contribute to ion selectivity 🤩

Big congratulations to @riottowow.bsky.social .bsky.social for winning an Anders Early Career Award at @lorneproteins.bsky.social ! Presenting his work on the lipid lined pore of the OSCA mechanosensitive channel. #lorneproteins2025

Proud of our latest work w/ the Zhang lab showing from structure & simulation how XPR1, the only known human Pi exporter, is regulated by InsP8 & KIDINS220 + Pi selection & permeation through a channel-like “knock-kiss-kick” mechanism 🚪💋🦵 💻 by @ciarawallis.bsky.social & @riottowow.bsky.social

Excited to be going to #bps2025 in LA!

I should have included one of the nice figures from the paper! rupress.org/jgp/article-...

Excited to start the year with this paper with @elainetao.bsky.social. Using simulations we show sodium channel blocking drugs bind at many sites within the pore and fenestrastions rather than at a single distinct pose. @jgenphysiol.bsky.social @scienceanu.bsky.social #ionchannels hubs.la/Q031spy70

Season's Greetings from our (lab) family to yours! P.s. can you guess which lab member is which?? 🎄🎅🍪 Baking by @yiechanglin.bsky.social, Elaine Tao, ZhouYi Wang, @ciarawallis.bsky.social, + honorary member @caloflaherty.bsky.social ♥️

Delighted to publish my new molecular animation: DNA Break Repair by Homologous Recombination youtu.be/Xe-83tBcxhs

We’ve had nearly 3 years of review, review, review. We need reviews, but it’s blindingly obvious that Australian research needs much greater Government investment while those reviews are done. This was true 3 years ago. Still true now. By @drjr.bsky.social

Excited to share our preprint about volume regulated ion channels here! We solved structures of heteromeric LRRC8A:D channels and show how they are gated closed by pore-blocking lipids. Led by @antonylurie.bsky.social + David Kern #IonChannel #cryoem www.biorxiv.org/content/10.1...

I'm following the Friday trend to make my own word scramble. Mine is a bit of a historical mess, but lots of fun to try scholargoggler.com

It's great to be back in Canberra with my wonderful (and prize-winning) lab talking about channels, transporters, lipids, and simulations while drinking boba #scienceanu

Ok, trying to bring my community back together... I created a starter pack for lipids and membrane protein aficionados! Feel free to share, add and distribute, so we can come together again! 😍 go.bsky.app/AEeXh86

May be a bit premature, but here is the Starter Pack I am trying to populate for #IonChannel research. Ping me and I’ll add you obviously! (Or to be removed) go.bsky.app/6taxHfx @jgenphysiol.bsky.social @auditorynerves.bsky.social @plesslab.bsky.social @rainbowlabuol.bsky.social

I made a MD starter pack! Dm or reply to be added ☺️☺️ go.bsky.app/QQjPjbL