Beautiful “action potential” stained glass made by @laurenatlas.bsky.social Picked 🔵 because it reminds me of our #ChR2 optotagging experiments 🤓🧪

Our paper on the Bacteroidota BAM complex is out in @natmicrobiol.nature.com! With @madejmar.bsky.social We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria. doi.org/10.1038/s415...

“In a research paper from the @australiainstitute.org.au called *Cooking the books at the Australian National University*, David Richardson and @richarddenniss.bsky.social said the ANU's argument about its unhealthy financial position was "flimsy".” www.canberratimes.com.au/story/907948...

New week, new tool: Find our Protein Domain Designer tool to generate publication-ready protein domain diagrams here: domaindesigner.farnunglab.com

Elizabeth Hinde and Jorge Alegre-Cebollada to Receive 2026 Michael and Kate Bárány Award buff.ly/n6RrjdO

Join us for the next CryoEM Current Practices Webinar on 9/25/2025 at 12 PM ET / 9 AM PT with Dr. Sarah Clark who will sharing her research on the "Architecture of a Bridge-like Lipid Transfer Protein." Register here: us02web.zoom.us/webinar/regi...

Check out our preprint in which we determine how a class of potent protein antibiotics specifically kill P. aeruginosa without a need to enter the cell. doi.org/10.1101/2025... This is work from my PhD in the lab of @rhyswg.bsky.social and many collaborators who contributed amazing data!

Only single cell sequencing of the all these post docs will reveal why

Lipid droplets: Open questions and conceptual advances around a unique organelle. New review from Mike Henne (@hennelab.bsky.social), Emma Reynolds, and William: rupress.org/jcb/article/... #Biochemistry #CellMetabolism #LipidDroplets

After years in making, I am glad to be able to share our attempt on establishing a framework for combined functional and computational assessment of variant pathogenicity in the sodium leak channel NALCN: www.biorxiv.org/content/10.1...

Writing this piece for Science AAAS gave me a chance to pause and think about what truly matters - to me as a scientist and as a person. If you’re curious, I share my journey of building a new life overseas and the lessons it brought. www.science.org/content/arti...

Stability vs flexibility: reshaping archaeal membranes in silico This ‘fundamental’ study characterises the mechanics and stability of bolalipids from archaeal membranes using a minimalist, physics-based computational model. buff.ly/jCnRfkO

Delighted that our FtsEX-EnvC paper is now live at mBio! FtsEX-EnvC is a bacterial Type VII ABC transporter that activates key periplasmic enzymes during cell division. We found mutations that disrupt FtsEX-EnvC activity and a disulfide that leaves it permanently active. doi.org/10.1128/mbio...

🚨🧠🔬 A major breakthrough in molecular neuroscience: I am excited to share a new story from our lab, published in accelerated format today by @nature.com: "Delta-type glutamate receptors are ligand-gated ion channels" Read more here (free article link): rdcu.be/eGIKz

extremely cool!!!!

Second author asking the PI to be co-first

Seriously, not every paper needs to be an epic novel, modeled on Anna Karenina... www.embopress.org/doi/full/10....

Ultramarathons being a Group 1 carcinogen would be so freaking weird. www.nytimes.com/2025/08/19/h...

Why hasn't Preprint Peer Review caught on more? I discovered a small, but simple reason - authors are missing out on the JOY of getting feedback because they aren't notified when feedback occurs. more in thread below!

Previous preprint is now published in RSC Chemical Biology. If you are interested in plasma membrane labeling, see the paper! 👇 pubs.rsc.org/en/content/a...

Researchers from WEHI’s Parkinson Disease Research Centre have won the 2025 UNSW Eureka Prize for Scientific Research. The team has been honoured for their research unravelling how PINK1, a key protein linked to early-onset Parkinson’s disease, works. 🔗 www.wehi.edu.au/news/eureka-...

Membrane Biology: Nothing can replace polyunsaturated lipids Genetic studies reveal that polyunsaturated lipids do more than simply increase the fluidity of the cell membrane. buff.ly/O6hUXFG

Here is a demonstration of ice nucleation protein made by Pseudomonas syringe in my #Bio350 #Micronauts in my #Microbiology course at @univpugetsound @ASMicrobiology

📢 We are hiring #PhD students and #Postdocs at the @mpi-nat.bsky.social in in the Department of Theoretical and Computational #Biophysics in Göttingen 🇩🇪! 🔗 check our current job adverts at www.mpinat.mpg.de/grubmueller and find your project. Submit your #application today! #job

Happy to share a new preprint from the Clarke & Vallese (@fravallese.bsky.social) labs reporting #cryoem structures of two RBC stomatin complexes – with AQP1 & UT-B - continuing the SPFH theme from our recent vault preprint! This was a fun one and has been cooking for a while - read on for more! ⬇️

Final year PhD students, I know you’re desperately trying to finish experiments/revisions/submissions/write a thesis & just survive - but please spare a few minutes to apply to your dream postdoc labs. It easily takes A YEAR from first contact, even if everything goes to plan on both sides.

Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, Christian, @sokrypton.org, Bruno and many other amazing lab members and collaborators. www.nature.com/articles/s41...

27 simulations of capturing hundreds of lipid scrambling events reveal mechanisms of lipid translocation. However, according to reviewers, more evidence is needed on outside-the-groove scramblase activity. buff.ly/sVdXMyM

Three remarkable early-career researchers from ANU, Dr Emily Furlong, Dr Ashley Jones and Associate Professor Xiaolin Wang, have been recognised with prestigious ACT Young Tall Poppy Science Awards for their significant contributions to science. Congratulations! science.anu.edu.au/news-events/...

‘Seek Funding’ Step Added To Scientific Method

A bridge-like lipid transfer protein is critical for generation of invasive stages in malaria parasites https://www.biorxiv.org/content/10.1101/2025.07.25.666630v1

!!!!!!!! this is so cool

A beautifully written piece on a terrible time www.science.org/content/arti...

Doing a post doc

go.bsky.app/8zZNEGV Great resource to connect early career folks with more senior scientists looking to hire postdocs! 🧪

‘My salary is less than what the university pays for rent on Julie Bishop's Perth office.’ - a human story of ANU cack-handed cuts. www.facebook.com/share/p/1ZTL...

;)

Last reminder- Dr Rhys Grinter webinar @rhyswg.bsky.social is on in just a couple of hours- click through to obtain the link. #proteindesign #structbiol You can sign up for future event information and reminders here: australian-structural-biology-computing.github.io/website/ 🧶🧬

The ARC has “announced” an update on the proposed changes to its grant schemes. Key changes, in response to “nearly 350” submissions” (!) on their proposal, are 👇 More here: www.arc.gov.au/news-publica...

Excited to share our latest work using AI-designed proteins to block heme-piracy by E. coli. Published in @natcomms.nature.com. A team effort between my lab and the ‪‪@knottrna.bsky.social‬ ‬lab, with experimental work led by the talented @danielrfox.bsky.social www.nature.com/articles/s41...

In a study of professors, women got 378 new work requests over 4 weeks vs 118 for men. Women spent more time on service, advising & teaching; men on research. Orgs should track who is taking extra duties & ensure they are rewarded and distributed fairly. www.forbes.com/sites/kimels...

Amazingly, this gave us a high-confidence transmembrane channel for both mouse and human NS3, with oleic acids forming a bilayer-like pattern. Our group now call this the “fatty acid hack.” The #alphafold predictions with and without fatty acids shown below 👇

Super excited to share our latest work revealing impt of protein-lipid interactions for the pri fn of the Tol-Pal complex in maintaining outer memb lipid homeostasis in E. coli! Huge discovery by Nadege Lim in collab @pstansfeld.bsky.social @robincorey.bsky.social 1/7 www.biorxiv.org/content/10.1...

🌟 We are hiring! Seeking a postdoc to use molecular dynamics and AI to understand how ion channels are regulated by membrane lipids 🌟 Join us at #scienceanu with amazing collaborators and great working conditions! Email me (karri.anu.edu.au) or apply here (tiny.cc/corry). Please share & repost!

From today, every paper submitted to Nature -if published - will be accompanied by peer reviewers comments & authors rebuttal. We started the trial in 2020; we now want to open up the review process & showcase its role in shaping & improving papers 🧪 #AcademicSky www.nature.com/articles/d41...

Delighted to announce the release of Boltz-2, which demonstrates unprecedented accuracy in predicting structure and binding affinity! Congrats to Sara Passaro, @gcorso.bsky.social + @jeremywohlwend.bsky.social on this stunning achievement! 📄Paper: bit.ly/boltz2-pdf 💻Code: github.com/jwohlwend/bo...

MscL channel opens up asymmetrically! Check out our latest story, spearheaded by my brilliant postdoc Olga pubs.acs.org/doi/10.1021/...

We are looking for a postdoc to study biomolecular condensates and/or mechanosensitive membrane proteins. Please help spread the news 🙏 sites.rutgers.edu/shi-lab/look...