🌟 New Tool Alert! 
We present MemPrO – a toolkit for orienting and building membrane protein systems: 
✅ Membrane protein orientation 
✅ Mixed membrane building 
✅ Double membranes & curvature 
✅ Peptidoglycan cell wall support 🔗 github.com/pstansfeld/mempro 
📖 pubs.acs.org/doi/10.1021/...

Lorne Proteins 2026 🏖️🤩 Featuring speakers Elitza Tocheva, UBC, on outer spore membrane biogenesis for endospore formation in Firmicutes; and EMBO keynote speaker David Drew, Stockholm University, focusing on GLUT glucose transporters and Na⁺/H⁺ exchangers. 🔗 Register now at: www.lorneproteins.org

🚨My lab is hiring a postdoc!🚨 If you’re interested in working out the mechanism and physiological impact of bacterial lipid transport processes then please apply! Job advert is here: tinyurl.com/4swddfda Get in touch by email ([email protected]) for informal enquiries Please repost! Thanks!

be the bitch doing something yourself that you want to see in the world

Relying on ChatGPT to teach you about a topic leaves you with shallower knowledge than Googling and reading about it, according to new research that compared what more than 10,000 people knew after using one method or the other. Shared by @gizmodo.com: buff.ly/yAAHtHq

Super collaboration with @raffaeleieva.bsky.social and @fronzeslab.bsky.social on the LptDEMY complex.

ARC says they’ll announce DECRA and LIEF outcomes tomorrow (Tuesday 25th Nov). In recent times these announcements have been around 11am Canberra time. With 2 schemes on the same day, I assume they’ll announce one of them later in the day (probably DECRA first).

"We thank the reviewers for their helpful suggestions"

Latest RFDiffusion3 from the Baker lab.

Toxoplasma gondii carefully balances calcium between its organelles. This study shows the ER, via the SERCA pump, is central to controlling Ca²⁺ in the cytosol and mitochondria. 🔗 buff.ly/RFgcZgE

Just ported @ryanfeigenbaum.com's amazing color logic into a standalone, MIT-licensed library. Perceptually uniform palettes for your next generative art or design project. 🎨 meodai.github.io/pro-color-ha...

Biology of bridge-like lipid transfer proteins continues to be uncovered at a rather brisk pace. These things are important... Cool paper, congratulations!

[Resources] #AlphaFold protein and PPI prediction databases 1️⃣ Predictomes (genome maintenance & H2A/H2b) predictomes.org 2️⃣ Flypredictome www.flyrnai.org/tools/fly_pr... 3️⃣ Human interactome prodata.swmed.edu/humanPPI 4️⃣ BFVD (viral proteins) bfvd.steineggerlab.workers.dev 1/2

A handy translation guide for non-academic speakers.

Kat Blow has developed CCD2MD, a suite of packages for preparing co-folded outputs for MD simulations. Created for protein–lipid interactions in integral membrane proteins, it also works for peripheral and lipid-anchored proteins too. pubs.acs.org/doi/full/10.... github.com/keb721/ccd2md

Thrilled to share that the final piece of my PhD work is now on bioRxiv! biorxiv.org/content/10.1... With support from @nvidia and the @NSF, we used AlphaFold to screen 1.6M+ protein pairs, revealing thousands of potential novel PPIs. All data can be viewed at predictomes.org/hp

"After 16 years in academia, I’ve become more selective about collaboration. It remains a joy and a blessing, but I’ve also learned how quickly 'we' can turn wicked." #ScienceWorkingLife https://scim.ag/43ibPrT

What is the most profitable industry in the world, this side of the law? Not oil, not IT, not pharma. It's *scientific publishing*. We call this the Drain of Scientific Publishing. Paper: arxiv.org/abs/2511.04820 Background: doi.org/10.1162/qss_... Thread @markhanson.fediscience.org.ap.brid.gy 👇

Astonishing and in a way heartening to see what people are prepared to put up with to get the education they want.

Beautiful “action potential” stained glass made by @laurenatlas.bsky.social Picked 🔵 because it reminds me of our #ChR2 optotagging experiments 🤓🧪

Our paper on the Bacteroidota BAM complex is out in @natmicrobiol.nature.com! With @madejmar.bsky.social We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria. doi.org/10.1038/s415...

“In a research paper from the @australiainstitute.org.au called *Cooking the books at the Australian National University*, David Richardson and @richarddenniss.bsky.social said the ANU's argument about its unhealthy financial position was "flimsy".” www.canberratimes.com.au/story/907948...

New week, new tool: Find our Protein Domain Designer tool to generate publication-ready protein domain diagrams here: domaindesigner.farnunglab.com

Elizabeth Hinde and Jorge Alegre-Cebollada to Receive 2026 Michael and Kate Bárány Award buff.ly/n6RrjdO

Join us for the next CryoEM Current Practices Webinar on 9/25/2025 at 12 PM ET / 9 AM PT with Dr. Sarah Clark who will sharing her research on the "Architecture of a Bridge-like Lipid Transfer Protein." Register here: us02web.zoom.us/webinar/regi...

Check out our preprint in which we determine how a class of potent protein antibiotics specifically kill P. aeruginosa without a need to enter the cell. doi.org/10.1101/2025... This is work from my PhD in the lab of @rhyswg.bsky.social and many collaborators who contributed amazing data!

Only single cell sequencing of the all these post docs will reveal why

Lipid droplets: Open questions and conceptual advances around a unique organelle. New review from Mike Henne (@hennelab.bsky.social), Emma Reynolds, and William: rupress.org/jcb/article/... #Biochemistry #CellMetabolism #LipidDroplets

After years in making, I am glad to be able to share our attempt on establishing a framework for combined functional and computational assessment of variant pathogenicity in the sodium leak channel NALCN: www.biorxiv.org/content/10.1...

Writing this piece for Science AAAS gave me a chance to pause and think about what truly matters - to me as a scientist and as a person. If you’re curious, I share my journey of building a new life overseas and the lessons it brought. www.science.org/content/arti...

Stability vs flexibility: reshaping archaeal membranes in silico This ‘fundamental’ study characterises the mechanics and stability of bolalipids from archaeal membranes using a minimalist, physics-based computational model. buff.ly/jCnRfkO

Delighted that our FtsEX-EnvC paper is now live at mBio! FtsEX-EnvC is a bacterial Type VII ABC transporter that activates key periplasmic enzymes during cell division. We found mutations that disrupt FtsEX-EnvC activity and a disulfide that leaves it permanently active. doi.org/10.1128/mbio...

🚨🧠🔬 A major breakthrough in molecular neuroscience: I am excited to share a new story from our lab, published in accelerated format today by @nature.com: "Delta-type glutamate receptors are ligand-gated ion channels" Read more here (free article link): rdcu.be/eGIKz

extremely cool!!!!

Second author asking the PI to be co-first

Seriously, not every paper needs to be an epic novel, modeled on Anna Karenina... www.embopress.org/doi/full/10....

Ultramarathons being a Group 1 carcinogen would be so freaking weird. www.nytimes.com/2025/08/19/h...

Why hasn't Preprint Peer Review caught on more? I discovered a small, but simple reason - authors are missing out on the JOY of getting feedback because they aren't notified when feedback occurs. more in thread below!

Previous preprint is now published in RSC Chemical Biology. If you are interested in plasma membrane labeling, see the paper! 👇 pubs.rsc.org/en/content/a...

Researchers from WEHI’s Parkinson Disease Research Centre have won the 2025 UNSW Eureka Prize for Scientific Research. The team has been honoured for their research unravelling how PINK1, a key protein linked to early-onset Parkinson’s disease, works. 🔗 www.wehi.edu.au/news/eureka-...

Membrane Biology: Nothing can replace polyunsaturated lipids Genetic studies reveal that polyunsaturated lipids do more than simply increase the fluidity of the cell membrane. buff.ly/O6hUXFG

Here is a demonstration of ice nucleation protein made by Pseudomonas syringe in my #Bio350 #Micronauts in my #Microbiology course at @univpugetsound @ASMicrobiology

📢 We are hiring #PhD students and #Postdocs at the @mpi-nat.bsky.social in in the Department of Theoretical and Computational #Biophysics in Göttingen 🇩🇪! 🔗 check our current job adverts at www.mpinat.mpg.de/grubmueller and find your project. Submit your #application today! #job

Happy to share a new preprint from the Clarke & Vallese (@fravallese.bsky.social) labs reporting #cryoem structures of two RBC stomatin complexes – with AQP1 & UT-B - continuing the SPFH theme from our recent vault preprint! This was a fun one and has been cooking for a while - read on for more! ⬇️

Final year PhD students, I know you’re desperately trying to finish experiments/revisions/submissions/write a thesis & just survive - but please spare a few minutes to apply to your dream postdoc labs. It easily takes A YEAR from first contact, even if everything goes to plan on both sides.

Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, Christian, @sokrypton.org, Bruno and many other amazing lab members and collaborators. www.nature.com/articles/s41...

27 simulations of capturing hundreds of lipid scrambling events reveal mechanisms of lipid translocation. However, according to reviewers, more evidence is needed on outside-the-groove scramblase activity. buff.ly/sVdXMyM

Three remarkable early-career researchers from ANU, Dr Emily Furlong, Dr Ashley Jones and Associate Professor Xiaolin Wang, have been recognised with prestigious ACT Young Tall Poppy Science Awards for their significant contributions to science. Congratulations! science.anu.edu.au/news-events/...

‘Seek Funding’ Step Added To Scientific Method