Susan Arden, Folma Buss & team use proximity labelling & quantitative proteomics to define the MYO1E & MYO1F interactomes, revealing shared & unique binding partners. Highlight: journals.biologists.com/jcs/article/... Article: journals.biologists.com/jcs/article/... #OpenAccess #ReadandPublish

I'm really excited to break up the holiday relaxation time with a new preprint that benchmarks AlphaFold3 (AF3)/“co-folding” methods with 2 new stringent performance tests. Thread below - but first some links: A longer take: fraserlab.com/2025/12/29/k... Preprint: www.biorxiv.org/content/10.6...

‼️🚨Hi all! The next Bioc Soc Membrane Contact Site Meeting will be in Chepstow, UK 28-30th Sept 2026. Fantastic speakers with talk slots still available. Sign up & abstract submission now open - limited spaces so register early! Hope to see you all there. Please share + RT 🙏

University of Melbourne vice-chancellor Emma Johnston has died from complications associated with cancer, aged 52.

Why are you like this, Steve!?

Sweeping science cuts in 2025 halted clinical trials, erased public health data and forced researchers into impossible choices. “This year nearly broke me as a scientist,” one writes. Six researchers share their stories: buff.ly/u2MHIQo 🧪

Medical research matters! Australian scientists are making potentially lifesaving breakthroughs into the molecular mechanisms of brain tumours - discoveries with potential for commercialisation and global uptake. We should support them better via the MRFF and NHMRC.

Thanks Brett! Hey Charles, please start here and ping @lifeonthewedge.bsky.social and @paloha.bsky.social if you have any questions. FYI, the journal version of our paper will be out in a week 👀 github.com/Chromatin-St...

Crowd sourcing request!! I'm trialling some dev software and I'm looking for nice public tomograms to use as case studies. Downloading all tomos and looking for good examples is tedious. Can anyone recommend specific tomos from EMPIAR/CZI that have multiple STA targets? #teamtomo #cryoEM

Structural reorganization underlying stress-induced cytoplasmicsolidification in yeast https://www.biorxiv.org/content/10.64898/2025.12.22.696049v1

Steve is in the garden mentally preparing himself for Christmas..

Lorne Proteins 2026 🏖️🤩 Featuring speakers Elitza Tocheva, UBC, on outer spore membrane biogenesis for endospore formation in Firmicutes; and EMBO keynote speaker David Drew, Stockholm University, focusing on GLUT glucose transporters and Na⁺/H⁺ exchangers. 🔗 Register now at: www.lorneproteins.org

There's another reason. Some of us actually LIKE doing research. We LIKE searching, reading, thinking. I pity those who don't.

I’m excited to share that I’ve joined the Editorial Board of the Journal of Biological Chemistry. I look forward to serving this incredible community journal and engaging with exciting science! @asbmb.bsky.social 🧪

very unusual - a tRNA regulated anion channel

Congratulations to the Cater Lab's first ever graduate Parteek! Bachelor of Advanced Scince with First Class Honours - we are SO proud of you! Looking forward to another year of fun in the lab together in 2026! 🎓🔬🧪✨

myristic, palmitic and stearic acids, that neurons use for beta oxidation energy at rest and especially during high neuronal activity (www.nature.com/articles/s42...). This endogenous fatty acid pathway provides ~20% of total neuronal energy at rest, even at hyperglycemic conditions. 2/3

Oh to be a little Tardigrade walking across a microscopic slide. 🫧🐻🧪

What an end to 2026! Super proud of this crew. Pandemic PhDs deserve special recognition ❤️ congratulations @christanny.bsky.social & @alexlibert.bsky.social!!!! ( & welcome to your PhD @tayzwisler.bsky.social ) #UQ

Crisafulli LNP government’s first year devastates new renewable energy and storage investment in Queensland -Investment in large-scale renewable energy and storage projects in Queensland has fallen by more than 74 per cent reneweconomy.com.au?p=242471

Hanson at the Bondi memorial calling for students to be "rounded up" and cuts to immigration. The crowd muttering in agreement, and giving her a huge round of applause once she finishes. Everything is about to get so much worse in Australia

If anyone has any ideas that they would like to work on in choanoflagellates or Nematostella (or both) then please reach out!

AI design of a protein with thermal stability of 150°C doi.org/10.1016/j.cr... (AI: Actually Interpretable Assay-Informed Additivity Inference)

Congratulations to the Landsberg lab for a fantastic paper in Nat Comms on the structure of the YenTC toxin. Led by Yu Shang Low and Solace Roche. @dr-berger.bsky.social @sarahjpiper.bsky.social

Because it’s not getting reported on enough: Muslim fruit shop owner Ahmed al Ahmed, father of two, was the hero who bravely tackled one of the Bondi Beach shooters and took away his gun. He saved lives during a major terror attack. Say his name, and honor the lives of the victims of the shooters

Here’s an article from this year with the Australian gun lobby boasting that, with surging gun numbers, it was winning the fight against firearms control advocates. Blame guns. Blame anti-Semitism. Blame terrorists. Do not blame everyday Australians who marched for peace.

Vision models have directions in embedding space for concepts like “stripes” or "corgi" We show that protein language has directions for motifs, use this as a new way to detect and localize motifs! New preprint w/@ahmadshamail.bsky.social Feedback very welcome arxiv.org/abs/2511.21614 1/4

The Reck-Peterson lab at Weill Cornell Medicine is seeking a technician or staff scientist to work on Aspergillus projects. Broad background in fungal biology and techniques required. Bioinformatics skills preferred. Find out more at: reckpetersonlab.org.

This is fucking grim. Somebody invented a white guy, an "IT professional" named Edward Crabtree, who stopped the Bondi shooting and spread it all over the internet, which was picked up by AI agents and slop aggregation sites. The real hero is a fruit stand owner named Ahmed el Ahmed.

🤯

🏖️ 🌊 🤩 Christopher Barnes on molecular characterisation of vulnerable conserved coronavirus antigen:antibody complexes; and Rina Rosenzweig on chaperones recognition and prevention of protein misfolding in neurodegenerative conditions—at Lorne Proteins 2026! 🔗 Register now: www.lorneproteins.org

My excellent collaborator, Giulia Zanetti, is advertising for a post-doc to work on our shared MRC grant. Please consider applying to this great lab with a supportive mentor to do some exciting structural biology. www.ucl.ac.uk/work-at-ucl/...

💥I am excited to present our first research paper from the lab about caveolae lipid trafficking 🎉 Led by my fantastic PhD candidate @estherocket.bsky.social Here we looked into caveolae mediated dietary lipid uptake and how this process is mechanistically facilitated 👇 1/n

Thrilled to announce a new @natcomms.nature.com paper led by Alastair Stewart and team @victorchang.edu.au with contributions from @mcdevittlab.bsky.social Using #cryoEM we discovered unique features of the #Pseudomonas aeruginosa ATP synthase including an unexpected role for #zinc in the complex 🦠🔬

Were I in a govt that really cared about kids, I’d be banning new coal and gas mines with rather more fervour than the current ban on social media. Probably wouldn’t get the same boasting front pages in the Herald Sun and Daily Telegraph though…

The ARC have announced they’ll be running another round of Laureate Fellowships and Discovery Indigenous projects next year. These schemes were “paused” pending the review of the ARC grants system. Seems that is taking longer than expected … whoda thunk it? From www.arc.gov.au/news-publica...

We're losing the internet, let's hang out in the park

Alert for DP27 EOI applicants who “hold an Industry Fellowship in 2025”: ARC has contacted research offices advising that if the Fellowship will “remain active beyond the DP27 project assessment date (1 July 2027)” then you can only be listed on one (1) DP27 EOI. On the very eve of submission😱🙄

🚨 #CentresOfExcellence #CE26 announcement: ❗️Outcomes announced publicly for ARC Centres of Excellence 2026❗️ See ARC's RMS for list ➡️ https://rms.arc.gov.au/RMS/Report/Download/Report/a3f6be6e-33f7-4fb5-98a6-7526aaa184cf/288 /bot

Janelia is hiring! "Invent new imaging methods, molecular tools, or protein chemistry approaches" www.janelia.org/content/lead...

🛏️ Final call for accommodation! Today is your last chance to secure on-site accommodation at Mantra Lorne. Bookings close at the end of the day - once they’re gone, they’re gone. Don’t miss the convenience (and the view! 🏖️) of staying where the conference action happens. 🔗 www.lorneproteins.org

ARC says they’ll announce Centres of Excellence outcomes tomorrow (Tuesday 9th Dec). This is more than 2 months late, most likely due to the new security checking requirements for ARC grants. Centres of Excellence grants also need to have been approved by the Minister.

The ARC CEO has issued a public statement – a public statement they could have made weeks ago – about their proposed restructure & job losses. "No final decisions have been made." 🙃

I think too often physics students unconsciously have the idea that some people have brains that are "natural" for physics and some don't and who knows maybe that's true to some extent but regardless of natural tendency at some point everyone has to practice practice practice

🏨 🛌 Don’t miss staying at Mantra Lorne – bookings close 5 December! Make the most of the full Lorne Proteins experience by staying where the action is. 🌊 Ocean views, a short walk to the lecture theatre, and the perfect setting for collaboration. 😎 🔗 Book accommodation here: www.lorneproteins.org

#membrane seminars are back this THURSDAY for a super session with @dr-downes.bsky.social from the @giuliazanetti.bsky.social lab and Xin Zhou from the Ikonen lab! @felixmendu.bsky.social @ishier.bsky.social

The pathogenic bacteria Shigella avoids detection inside host cells by degrading RNF213, the protein responsible for sensing the presence of intracellular pathogens. Read more in the eLife Insight Article: buff.ly/1mIc6m0