@dazhi-li.bsky.social
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reposted by
Vanni Lab at UNIFR, Switzerland
10 days ago
This amazing work by
@danialv.bsky.social
and Bodan Hu is now out in peer-reviewed form at
@cp-cell.bsky.social
with a lot of new simulations! Check it out if interested in lipid transport!
add a skeleton here at some point
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Reinisch's lab work with the Vanni's lab is online in Cell!! Combining cryoEM and MD simulations, we reveal how the bridge-like lipid-transfer protein VPS13A works with the scramblase XK to deliver lipids to plasma membrane and redistribute them across the bilayer.
www.cell.com/cell/fulltex...
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Mechanism of lipid transfer by bridge-like protein VPS13A and the scramblase XK
The cryo-electron microscopy structure of the bridge-like lipid-transfer protein VPS13A in complex with the scramblase XK—coupled with molecular dynamics simulations—suggests that VPS13A-transported l...
https://www.cell.com/cell/fulltext/S0092-8674%2826%2900586-6
7 days ago
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Lipid scramblases and BLTPs are key to regulate cellular lipid dynamics. Justin Korfhage and I described in-vitro methods to study lipid scrambling by protein insertases and ATG2-mediated lipid transfer on artificial lipid droplets.
www.sciencedirect.com/science/chap...
6 months ago
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