Wee thread 🧵⬇️ on our new #glycotime with @siglecdude.bsky.social John Klassen and @glycocode.bsky.social 🥳 where we show Siglecs as molecular precision tools, able to recognise sialylated glycans with surgical precision in their natural environment, not bad for a lectin! 😎 doi.org/10.1038/s420...

I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗 beta.ideas.lego.com/product-idea...

Congratulations @olzmannlab.bsky.social @arrudalab.bsky.social! Really outstanding and important work!

Amazing PhD @cristianrocharoa.bsky.social and I have collected our thoughts and questions (many!) on lipid scramblases in this review: www.sciencedirect.com/science/arti... If you are interested in lipid transport and metabolism, membrane asymmetry and membrane protein function, give it a read!

New preprint from the lab together with @labvanni.bsky.social. We looked what happens to ER generated free very long chain fatty acids.. VLCFAs are partionig into lipid droplets and are extracted from the hydrophobic core by Fat1. www.biorxiv.org/content/bior...

PhD positions in my lab (AI for Science), but with special preference for people who complement our current activities or are enthusiastic about contributing to our on going work. Looking for technically strong, independent and proactive candidates. www.chalmers.se/en/about-cha...

Please REPOST (“likes” don’t help in diffusion!) and consider applying: we work in such a fantastic context, we ask so interesting questions, and we have such a collegial and best-willing atmosphere… CRBM = Happy & Good Science

Please share!!! I am looking for a postdoctoral researcher to join us. Focus will be on exciting collaborative projects on lipids and membrane biology, pushing the boundaries of in silico "reconstitutions". Previous experience with molecular dynamics simulations of biological systems a strong plus!

We have several Master’s thesis projects available in the D’Angelo lab, spanning different areas of lipid biology/biochemistry. If you know someone who might be interested, we’d really appreciate you sharing this. #lipidtime www.epfl.ch/labs/dangelo...

Please share🙏: Our lab opens 2 PhD positions to investigate fungi's evolution: #Barcelona Wet lab in Biochemistry/Structural Biology of cryo-tolerant fungi www.upf.edu/documents/d/... Computational in Physical Chemistry of cellular processes under extrem environments www.upf.edu/documents/d/...

I finally made my webpage, check it out: pilarcossio.org

New preprint from the lab! Triglycerides act like salt on ice: they solubilize cholesterol esters and drive lipid droplet growth. The TG/CE ratio shapes both droplet size and proteome, mirroring lipoprotein organization. www.biorxiv.org/content/10.6...

The work by @danialv.bsky.social is now out in @pnas.org with a few changes after peer-review. Have a look if you are interested in lipid transport by bridge lipid transfer proteins (BLTPs)... www.pnas.org/doi/10.1073/...

Happy to finally share the amazing results of our long-term collaboration with Karin Reinisch’s lab on how bridge lipid-transfer proteins (BLTPs) cooperate with partner proteins to orchestrate lipid delivery. A quick thread (1/7) www.biorxiv.org/content/10.6...

Experimental tour-de-force from Anne-Claude Gavin's lab: selectivity mapping of 39 lipid transfer proteins reveals ~500 new LTP-lipid pairs. Molecular modeling by @mahmoudmoqadam.bsky.social, @rezatalandahti.bsky.social & Florian Echelard. @cbubergen.bsky.social www.nature.com/articles/s41...

Join us for the 2026 Glycolipid & Sphingolipid Biology Gordon Research Conference (GRC). 📍 Renaissance Tuscany Il Ciocco (Italy) 🗓️ March 22 - 27, 2026 Theme: "Molecular Codes of Cell Identity and Recognition" #LipidResearch #Sphingolipids #GRC2026 #ScienceConference #Lipidtime

Join us for a two-and-a-half-day meeting in the scenic Wye Valley, to discuss how membrane contact sites shape cellular homeostasis across organelles, organisms, and approaches. 📍 Chepstow, South Wales, UK | 🗓️ 28–30 September 2026 👉 : www.eventsforce.net/biochemsoc/f...

TT in Experimental Biophysics The Danish Institute for Advanced Study and the Dept of Physics, Chemistry and Pharmacy at the University of Southern Denmark is hiring a tenure track Assistant Professor in Biophysics or a related discipline fa-eosd-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...

The Frankfurt Institute for Advanced Studies (FIAS) and the newly funded Cluster of Excellence SCALE are seeking several Independent Research Group Leaders to drive theoretical and computational research in molecular and cellular life science. fias.institute/de/das-fias/...

Happy to share our cryoEM Ensemble Optimization method! 🎉It infers optimal structures and their weights directly from individual cryoEM images - no maps just physics! with David Sliva-Sánchez, @erikhthiede.bsky.social & Roy Lederman www.biorxiv.org/content/10.6...

This is an exciting story! Happy to have contributed a little with @mudgal17.bsky.social. So many things we don't (yet) understand in membrane biology...

Thrilled to share that the work from @cristianrocharoa.bsky.social, identifying TMEM170 proteins as lipid scramblases that associate with bridge lipid transporters, is now out in @natsmb.nature.com Unexpectedly, the scrambling pathway does not "feed" directly into the BLTP cavity... rdcu.be/eRSst

Thrilled to share our latest work showing that the bridge lipid transport protein ATG2A transfers diacylglycerol (DAG), and some TAG/PA, from the ER to LDs, thereby recruiting DGAT2 to drive local TAG synthesis, promoting LD expansion while protecting ER membranes. www.nature.com/articles/s41...

🌍Open call: Junior Group Leader positions! Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery. Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...

**Job Alert** Exciting postdoc position available: theoretical and experimental cryo-EM studies of flexible biomolecules. Competitive salary, collaborative environment at NYSBC and Flatiron Institute. Please share!! and contact: [email protected]

We (@sobuelow.bsky.social) developed AF-CALVADOS to integrate AlphaFold and CALVADOS to simulate flexible multidomain proteins at scale See preprint for: — Ensembles of >12000 full-length human proteins — Analysis of IDRs in >1500 TFs 📜 doi.org/10.1101/2025... 💾 github.com/KULL-Centre/...

We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3

🚨🚨🚨 We are launching the 2nd application round for the Erasmus Mundus Joint Master’s Program MemBioMed, offering cutting-edge training on exploring the complex behavior of cellular membranes & unlocking their therapeutic potential. Students can apply here: life.univ-cotedazur.eu/internationa...

Thanks to @snsf.ch, we are hiring two PhD students to investigate frontier topics in lipid biology using a combination of MD simulations and experiments. Preferred starting date: ASAP. Fribourg - and Switzerland - are quite nice, for both work and private life! Please spread the word!

Please spread the word! 10 days left to apply for this #sciencejobs as Assistant Professor Tenure Track in Quantitative Cell Biology 👩‍🔬 @izb-unibern.bsky.social @unibe.ch! ohws.prospective.ch/public/v1/jo... #QueerInSTEM #DisabledInSTEM #BlackInSTEM #WomenInSTEM #CarersInSTEM #AcademicSky #HigherED

This is an really amazing opportunity. If you get it, you can essentially pick you institute. The package really is rather competitive.

Job alert 📣 Our faculty looks for a Junior Professor W1 with tt to W2 in Membrane Biology! We are looking for #ECRs working on membrane biogenesis,contact sites,composition & other aspects of membranes in 🌱 and other organisms! DM me if you need more details! jobs.ruhr-uni-bochum.de/jobposting/f...

Ne manquez pas le 20e GERLI International Lipid Meeting, Strasbourg, 3-5 nov 2025 Rejoignez chercheurs et experts pour explorer les dernières avancées en biologie des lipides, assistez à des conférences, posters et prix scientifiques ! Plus d'info : : www.gerli.com/congres/welc...

We are hiring! If you are looking for a postdoc position and you are interested in signaling lipids and proteomics, come join us in beautiful Switzerland! More information on www.epfl.ch/labs/gr-schu...

Happy to share the latest from the lab, led by Daniel Alvarez, in collaboration with @lizconibear.bsky.social‬. In this AA-MD tour-de-force, we delve deep into the mechanism and energetics of lipid uptake by bridge-like lipid transfer proteins, and we learn a few interesting things along the way...

Happy to share the latest work from the lab, led by @mudgal17.bsky.social‬, in collaboration with the Weis lab @ethzurich.bsky.social. How do nuclear membranes fuse during NPC assembly? We answer this question in our latest work, where we identify a new mechanism for membrane fusion… (1/13)

Hey there!✨I’m thrilled to share that our latest research, in collaboration with the Tontonoz Lab (UCLA), has just been published in Nature Metabolism. Our study explores the fascinating role of polyunsaturated fatty acids in fat storage. Check it out! @labvanni.bsky.social @natmetabolism.nature.com

I am looking to hire a protein #biochemist, #biophysicist or structural biologist: efzu.fa.em2.oraclecloud.com/hcmUI/Candid... - 2-year position working on lipid transport proteins. - Experience in protein expression, purification and biochemical and biophysical assay development. Please share!

Learn about #LipidDroplet #biology, their role in human disease and more at EMBO Workshop "Lipid Droplets: Cell-Biological Control of #Metabolism" in Sant Feliu de Guíxols, Spain, 21–26 September 2025 Deadline: 10 June 2025 meetings.embo.org/event/25-lip... #EMBOlipidDroplets #EMBOevents 🧪

Cette année le @cnrs.fr ouvre une Chaire de Professeur Junior "Méthodes de modélisation et simulations moléculaires" pour rejoindre à labo à Toulouse (@laascnrs.bsky.social), Palaiseau (LIX) ou Nancy (LORIA), vous avez jusqu'au 14 juillet pour candidater ! emploi.cnrs.fr/Offres/CPJ/C...

Excited to share the new work from the Carvalho lab @dunnschool.bsky.social! 🎉This was part of my PhD & a collaboration with the @labvanni.bsky.social & Ernst labs! Big thanks to everyone involved! 🙌 @jcb.org Read more: doi.org/10.1083/jcb.... (1/2)

Indeed, Marc and Yuta are great!! Happy to have contributed to this story with superstar PhD @cristianrocharoa.bsky.social. For lovers of (polyunsaturated) lipids, mitochondria, fat and molecular mechanisms!

Check out two great preprints from the Tontonoz lab, linking LPCAT3-mediated phospholipid remodeling to dietary fat intake and cold response www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.1...

ICYMI: New online: Structural clues about bridge-mediated lipid transfer

The abstract submission deadline for the 2nd edition of our #EMBOLipidDroplets Workshop (21-26 September 2025) is approaching. Check out the agenda with an amazing lineup of speakers and submit your abstract before 10 June 2025! @embo.org @biologists.bsky.social meetings.embo.org/event/25-lip...

PFAS surfactants self-assemble into vesicles. Exciting results based on Martini simulations from Bei Yan, highlighted in Nature: www.nature.com/articles/d41...

Happy to share the latest from the lab, with @lizconibear.bsky.social lab. The title says it all: we identified poorly characterised TMEM170 proteins as lipid scramblases that physically associate in the ER with BLTP1/LPD-3/Csf1. We think this has key implications in lipid transport/homeostasis...

We have an open PhD position in molecular modeling to work on the recognition of pollutants by fish receptors. More information and application procedure: www.jobbnorge.no/en/available... Come and work with us ;)

At membrane contact sites, bridge-like transport proteins, e.g. LPD-3, mediate bulk lipid transfer between cellular organelles. @nature see cryo-EM structure of native LDP-3, and gain insights into its functioning and interaction with other proteins and lipids. shorturl.at/lycuz & shorturl.at/ARpUK

Super excited to share this as my first post with the 🦋 world! In my first co-correspondent article, we (@Mayra Borrero @Agnieszka Chacińska @IMOL Institute) look at the roles of lipids in mitochondrial protein import complexes (spoiler: there are plenty!) &call for methods (spoiler: there are few!)