Absolute Quantification of Fluorescent Protein Fusions by Proteomics by Andrej Shevchenko and team: www.biorxiv.org/content/10.1...

🔬 Congratulations to Sarah Cohen (@cohenlaboratory) (@UNC) on receiving ASCB’s 2025 WICB Junior Award for Excellence in Research! This honor celebrates exceptional early-career contributions to cell biology and strong potential for continued leadership. #ASCB #CellBiology

A molecular-resolution look into the near-native architecture of the spinach chloroplast🌱. This one was a long time in the oven, but we're happy to finally share our "version of record". What long-standing debates did we settle? Check back for a short thread🧵 on Monday. #TeamTomo #PlantScience 🧪🧶🧬🔬🌾

Now #published @pnas.org: "A model for boundary-driven tissue morphogenesis", a great #biophysics #devbio collaboration led by @danielalber.bsky.social @zhaoshh.bsky.social: doi.org/10.1073/pnas.2505160122 @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social @flatironinstitute.org

Lipid droplets: Open questions and conceptual advances around a unique organelle. New review from Mike Henne (@hennelab.bsky.social), Emma Reynolds, and William: rupress.org/jcb/article/... #Biochemistry #CellMetabolism #LipidDroplets

This is another must read - great week for organelle bio tools this week!

It’s journalism’s obesogenic environment problem. Everyone knows you’re meant to eat your greens (speak to domain experts, double-check), but social media has created a sea of cheap and convenient (open an app), hyper-palatable (sensationalised, alarmist), nutrient-poor (dubious veracity) options.

Paper alert!🧪 We derive a theory that underpins interface resistance with a physical foundation and look at how it changes droplet growth and recovery kinetics! Awesome collab with @bosste.bsky.social Tyler Harmon @hymanlab.bsky.social @m-pol.bsky.social and Frank Jülicher @mpipks.bsky.social 1/4

Meet Daxiao Sun, a shared postdoc in the lab of Alf Honigmann @biotec-tud.bsky.social and @hymanlab.bsky.social @mpi-cbg.de. Happy #PostdocAppreciationWeek! 🎉 Video by Magdalena Gonciarz @cmcb-tud.bsky.social

ABCA7 variants impact phosphatidylcholine and mitochondria in neurons www.nature.com/articles/s41...

Spectacular work. Absolutely spectacular. Go check out the paper. It truly is #lipidtime now

Early-career researchers: want to run your own lab? 🌟Max Planck Research Groups offer 6+ years, up to €2.7M in funding, open-topic freedom, team support & tenure-track opportunities. Intrigued? 😃Apply by Oct 14, 2025! www.mpg.de/max-planck-r...

I wrote an article summarizing our recent findings of beta cell cilia - neuron contacts. It was fun to elaborate a bit on the exploration of #openaccess #volumeEM datasets: analyticalscience.wiley.com/content/arti...

This is absolutely a must read. We are in deep trouble and I am even less optimistic than the authors.

AI can now generate fake microscopy images that are nearly impossible to detect. A serious threat to scientific integrity—and we’re not prepared for it. Commentary in @natnano.nature.com #nanotechnology

The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona | Science Advances www.science.org/doi/10.1126/... Congratulations @vcmentowski.bsky.social for solving a remarkably challenging molecular puzzle

Pretty sure everyone has seen it already, but if you are also late like me, here is an excellent lipidtime paper by @nadlerlab.bsky.social and Co. One step closer to understanding the spatiotemporal lipid diversity in cells!

W/ critical contributions from @mtrani.bsky.social, Alba Villaronga Luque, @yonitmms.bsky.social, Allyson Ryan, & in collab w/ @carldmodes.bsky.social @csbdresden.bsky.social & @campaslab.bsky.social @poldresden.bsky.social. Funded by #EICPathfinder @ec.europa.eu. Background thread coming soon!

(1/14) I’m happy and proud to introduce: SpinePy – a framework to detect the "spine" of gastruloids and measure biological and physical signals in a local dynamic 3D coordinate system. www.biorxiv.org/content/10.1...

My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...

We have updated our preprint "A green lifetime biosensor for calcium that remains bright over its full dynamic range" with some new data - including this photo showing the difference in color for the Turquoise and Green lifetime probe. www.biorxiv.org/content/10.1...

This is an really amazing opportunity. If you get it, you can essentially pick you institute. The package really is rather competitive.

I like this...

Previous preprint is now published in RSC Chemical Biology. If you are interested in plasma membrane labeling, see the paper! 👇 pubs.rsc.org/en/content/a...

Congratulations to Kai Simons, one of our founding directors, for receiving the Cothenius-Medal of the German National Academy of Sciences Leopoldina @leopoldina.org for his insights into the function of cell membranes. 🎉 www.mpi-cbg.de/news-outreac...

Beautiful work from Jeremy's lab - a cool illustration of the power of bifunctional lipids as discovery tools. Congrats to all authors - the final manuscript is a really complete lipid cell biology story from probe design to mechanistic investigation. Chapeau!

Patrick's paper is finally out, a label-free method to measure the composition of multicomponent biomolecular condensates!

New #preprint: "Control of lumen morphology by lateral and basal cell surfaces", a great #biophysics collaboration with Chandraniva Guha Ray, @markusmukenhirn.bsky.social, Alf Honigmann @biotec-tud.bsky.social @poldresden.bsky.social. arxiv.org/abs/2509.04316 @mpipks.bsky.social @mpi-cbg.de

Recently, both our team and the Richardson/Estelle/Strader teams showed that ARF transcription factors are actively degraded. In this new preprint, Martijn de Roij explores the requirements and relevance of ARF degradation (1/7)

If you're interested in trafficking of #myelin constituents in #oligodendrocytes, and of course you are, you may want to check out our new preprint. It's very nice PhD work by @sophiesiems.bsky.social, and we're grateful to all who contributed! www.biorxiv.org/content/10.1...

Congratulations Milena! I could not be more proud of you. This is great news for #lipidtime research... 👀

Thrilled to share 🎉 I’m starting my lab at University of Zurich, DMLS as Assistant Professor (tenure track) from Jan 2026! The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

This is an amazing piece of work! It was a true pleasure seeing this story come together. @mpi-cbg.de going on a streak of @nature.com papers!

Dresden researchers @paveltomancak.bsky.social @bruvellu.bsky.social, Carl Modes, @cuencam15.bsky.social ‬ & colleagues published in @nature.com that a tissue fold in fruit fly embryos buffers mechanical stresses & may have evolved in response to mechanical forces. www.mpi-cbg.de/news-outreac...

Happy to share our work on uMAIA, a framework for building metabolomic atlases from mass spectrometry imaging. With uMAIA, we mapped the lipidome of zebrafish development, uncovering spatially organized metabolic programs . www.nature.com/articles/s41... #developmentalbiology #MSI #lipidtime

Excited to share my postdoc work from the Eggeling lab in Jena (@leibnizipht.bsky.social, #FSUJena, #KTHuniversity) on bringing smart microscopy to super-resolution MINFLUX: event-triggered MINFLUX microscopy.

Finally out! With our "PhotoCells" we can dynamically control membrane viscosity in living cells revealing how physical properties of membranes fine-tune cellular logistics. Truly interdisciplinary and collaborative research, made possible thanks to all our fantastic collaborators. Congrats to all!

RNA droplets that grow and segregate by ribozyme catalysis. Check out our latest preprint www.biorxiv.org/content/10.1101/2025.08.29.673008v1

This is an amazing opportunity in a great lab!

This reminds me how much I hate it when I have to watch a video tutorial. The reason books and libraries have been successful is that you can parse the information they contain many times faster than with a linear media or someone talking

We are happy to present the magnum opus of Sjoerd Woudenberg, at the close of his PhD – Transgenerational inheritance of the polarity axis in a fern embryo…a thread (1/17) tinyurl.com/4y53xekv

We are looking for a Master’s student to join a project on in vitro reconstitution of signaling networks in pathogen–host interactions: combine protein biochemistry, fluorescence microscopy & image analysis. Deadline: September 15. Find out more and apply here: ist.ac.at/en/job/maste...

On our way to the @mpi-cbg.de faculty retreat with @paveltomancak.bsky.social @nadlerlab.bsky.social, Eric, Alex - using the only acceptable means of transport.

Tour de force from @nadlerlab.bsky.social . The value of solving a hard problem with beautiful chemistry: insights that upend conventional thinking re: lipid transport. You’ve got to read the thread, I’m not giving away the juice! It’s fantastic! Congrats 🎈🎊🍾🎉

Great to see this work on imaging cellular lipid logistics in Nature, where it belongs. Chapeau! Many gratulations to Andre, Alf and their co-workers!

I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions. Descriptions and links in the following two posts.

🚀 Fresh science from the BIOTEC & @tudresden.bsky.social: A collaboration between Alf Honigmann's lab and @nadlerlab.bsky.social at @mpi-cbg.de opens a new chapter in #imaging of #lipids. 🔗 Read more ➡️ tud.link/xz4e1f #CMCBnews

Research team @nadlerlab.bsky.social, A. Honigmann @biotec-tud.bsky.social, B.Drobot @hzdr.bsky.social, M. Hof @heyrovskeho-ustav.bsky.social develops approach to visualize lipids in cells & uncovers the main transport mechanism for lipids within the cell. @nature.com www.mpi-cbg.de/news-outreac...

🗺️🔬 A first-of-its-kind map of lipid traffic is demystifying an important yet elusive aspect of how cells work. Read the study, out now in @nature.com, by Allen Distinguished Investigators Alf Honigmann, @nadlerlab.bsky.social, and collaborators: www.nature.com/articles/s41... #FrontierScience