The University of Washington Department of Microbiology seeks to hire an Assistant Professor, Tenure Track. apply.interfolio.com/185622 We're interested in mechanistic approaches to study physiology and/or pathogenesis of bacteria and viruses, as well as microbial community interactions.

The ZMBH welcomes Dr. James Sáenz @jamessaenz.bsky.social as new Professor in Molecular Biology. James previously led a research group at B CUBE - Center for Molecular Bioengineering of Dresden University of Technology.

An internal compass: #pigeons use magnetically responsive immune cells in their livers to sense Earth’s magnetic field, helping them navigate without visual cues like the sun. www.youtube.com/watch?v=-s8i... @mpi-animalbehav.bsky.social @science.org

Researchers have identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation. https://scim.ag/4nTQ3nq

TL;DR: We've identified more than 100 cases of apparent manipulation in Thermo Fisher Scientific's antibody verification data. @sholtodavid.bsky.social @johanduchene.bsky.social reeserichardson.blog/2026/05/28/h...

Any1 is a #phospholipid scramblase involved in #endosome biogenesis. From Jieqiong Gao, Christian Ungermann and colleagues: rupress.org/jcb/article/... 📕 Part of #Lysosomes 2026: rupress.org/jcb/collecti...

Hallo, Dresden, you hotbed of #lipidtime research! Thanks to @nadlerlab.bsky.social for hosting me at @mpi-cbg.de yesterday — and looking forward to giving the plenary talk at the European Symposia of Bioorganic Chemistry meeting later today!

Lazar Ivanović, Wanda Kukulski and colleagues dissect the molecular basis of tricalbin-mediated membrane contact site organisation in cells. Highlight: journals.biologists.com/jcs/article/... Article: journals.biologists.com/jcs/article/...

🚨 New preprint from the Feigin Lab! 🚨 www.biorxiv.org/content/10.6... Opioids have profound effects on the pancreatic cancer microenvironment! An FDA-approved opioid antagonist that doesn't cross the blood brain barrier decreases tumor aggressiveness in a mouse model of pancreatic cancer!

Lovely new preprint on how membrane microdomain formation controls endosomal protein sorting, from Kam Shan Hu, Barth Grant, @barrlab.bsky.social and colleagues:

Open Postdoc Position - Giant E3 ligases: mysterious mechanisms & non‑protein substrates. Interested? Join us to uncover how these molecular giants tag lipids, RNAs, sugars beyond proteins, on organelles and pathogens, to defend the cell. Details & Application here www.imp.ac.at/career/open-...

🚨first Bartman lab preprint! it's an LC-MS method to measure "total Coenzyme A" (sum of all acyl-CoAs). this will let us study coA synthesis flux using heavy-isotope tracing! huge congrats to first author Amelia Taylor and star coauthor @mzspectrum.bsky.social ! www.biorxiv.org/content/10.6...

It's finally out! Molecular architecture of mammalian AP3:ARF1 carriers - a mechanism for lysosomal membrane protein trafficking - from a combination of #biochemistry, #cryoET and #cellbiology 📝 Paper: www.science.org/doi/10.1126/... 🧵 Thread: subsequently #teamtomo #membranetrafficking

Delighted to welcome our new PI, Daxiao Sun who is starting her lab at SMART after a postdoc with @hymanlab.bsky.social @mpi-cbg.de and Alf Honigmann @biotec-tud.bsky.social Daxiao’s group will investigate how biomolecular condensates regulate cell junctions and tissue morphogenesis. Welcome!

How do cells communicate? They use Sms1 ! 🙂 More seriously, Sms1 is the scaffold of the pheromone-MAPK signalling cascade in fission yeast, which @borissieber.bsky.social et al discovered. Have a look at the paper 👇 @biology-unige.bsky.social

S. cerevisiae is emerging as a whole-cell factory for producing pharmaceutically relevant amines. This Review by the Francesco Mutti lab in #ChemBioChem (@chemistryeurope.bsky.social) maps strain-engineering strategies that could make amine biocatalysis more scalable. doi.org/10.1002/cbic...

This is very, very cool. Congratulations!

On June 30 at noon, the next #DGZ Focus Workshop on #MembraneOrganization & #ContactSites will take place, organized by Sabrine Buettner & Katja Zieske. Speakers: André Nadler @nadlerlab.bsky.social, Suzan Kors, Zexi Xu and Emma Fenech. Join us!

i.e. it is just fairly good mimicry of consciousness, parasitic on ours. And this seems so obvious. Yet smart people keep falling for it. Is this really so hard?

New paper out! Left-handed DNA cannot bind to natural, right-handed DNA. This leads to lower background if it is used as a probe in DNA-PAINT. Using Fluorigenic DNA-PAINT with left-handed DNA allows for low background, fast 3D DNA-PAINT! Congrats, Bas! skeetorial: 1/x pubs.acs.org/doi/full/10....

The helium shortage is now unavoidable. Another wonderful follow-on to the Iran War, and if you think helium doesn’t matter much, think again:

Building bridges: BLTP2 forms ER-plasma membrane contact sites. @flofroehlich.bsky.social discusses two recent studies from Dziurdzik et al. & Dai et al. (doi.org/10.1083/jcb.... & doi.org/10.1083/jcb....): rupress.org/jcb/article-... #ER_Literature

Congratulations to @hellmichgroup.bsky.social! The Max Planck Society awarded her a Max Planck Fellowship. We are happy to have her as a Max Planck Fellow and look forward to intensifying our collaboration with her. www.ice.mpg.de/556225/ute-h...

Bacterial immune proteins have repeatedly evolved to become parts of eukaryotic immunity. But how? Our new preprint uncovers a recent horizontal transfer event & shows how eukaryotes co-opted a toxic bacterial immune protein 🦠🧪🧵 1/

I really like this.

☕Paquola et al. present a technique named lipid-trap mass spectrometry (LTMS) to study lipid–protein interactions directly captured from mammalian cells. bit.ly/4tEPW10

What membrane properties do cells maintain through regulation of lipid metabolism? In a new paper, we identify intrinsic curvature stress as one such parameter and show how different (eukaryotic) cell types employ different lipids to do that www.cell.com/cell-reports...

These images show live embryos of animals (jellyfish, crustacean, worm, sea urchin, sea squirt, beetle) and one of animals closest single-celled relatives. They were captured taking advantage of fluorescent proteins localised on the outer membrane of cells, allowing us to observe cell outlines. 1/9

📯Proud to share a preprint of a joint paper with Michael Timme and @melolab.bsky.social on how ceramides disrupt hexokinase binding to VDACs and modulate channel tilting. Our CG-MD simulations reveal a potential mechanism by which ceramides may induce apoptotic cell death📯 bsky.app/profile/bior...

That is very good news. And knowing that the @erc.europa.eu takes feedback from the community is encouraging.

Anthony Hyman @embl.org & @mpi-cbg.de @hymanlab.bsky.social & Clifford Brangwynne @princetonupress.bsky.social & @hhmi-science.bsky.social receive their 2023 Breakthrough Prize at the Awards Ceremony in Santa Monica,LA, April 18, by Eileen Gu & @mrgatoasdf.bsky.social! www.mpi-cbg.de/news-outreac...

🚨New Pernas Lab Preprint is live!! 🚨 Here we show that mitochondria shed "new organelles" that engulf lysosomes and become acidified compartments during intracellular infection! Video below shows SPOTs acquiring a lyso (C: matrix, Y: OMM, R: Lyso) 🔬. 🔗: www.biorxiv.org/content/10.6...

@flofroehlich.bsky.social discusses two recent studies from Dziurdzik et al. & Dai et al.(doi.org/10.1083/jcb.... & doi.org/10.1083/jcb....) describing a plasma membrane ER contact site formed by BLTP2 and its adaptor proteins. rupress.org/jcb/article-... #ER_literature

Fantastic work. What a #lipidtime to work in.

Congrats!!! Amazing news.

Thought-provoking

Interested in caveole and/or lipid metabolism? We have two master thesis projects available in the lab @unipotsdam.bsky.social starting September or October. For more details 👇 www.matthaeus-lab.de/post/04-2026...

Pro-tip: Before I submit my proposal, I read it again, but after 2 glasses of wine on an empty stomach. Places where it isn't totally clear to you in that state, it not going to be clear to the reviewer. Edit that bit.

Interested in Physics of Life? Curious about what are the scientific questions we study at @poldresden.bsky.social ? You can learn that in less than 3 min 🤩👇 Thanks to Avanga Film production for the great video 🎬

Out now in Nature Communications! We show that Dictyostelium vaults associate with ER and NE membranes in situ and encapsulate ribosomes with defined orientations, shining new light on their cellular function! #TeamTomo #TeamMassSpec #ProtistsOnSky www.nature.com/articles/s41...

Exciting to see this out in its final form! Wonderful work led by @probablycarmen.bsky.social. Want to know why protrusions are better at initiating immune signaling in #Tcells? Look no further. Link to Carmen’s 🧵 on the preprint bsky.app/profile/prob...

Our #UExM efforts with @gautamdey.bsky.social & @moorefound.bsky.social featured in @nature.com this month. Beyond the #science, every image is a thing of beauty. I think a world-tour exhibition has to happen at one point. #Expansion #Microscopy

‪ On April 15th, @leopoldina.org welcomed its new members of Class II Life Sciences. Meritxell Huch @merihuchlab.bsky.social, director @mpi-cbg.de, is among them and received their membership certificate together with fifteen other new members. Congratulations! 🎉 Photo: Marlene Gawrisch | Leopoldina

Lipid-CLEM by @mathilda95.bsky.social on the Cover of @natcellbio.nature.com! Link to article: www.nature.com/articles/s41...

Original image from 2011 of what I just had seen under the microscope when I ran into @oliverrocks.bsky.social’s office to show him. Turned out he’d observed this too, had no idea what it was either, but was just as stunned and curious as I was. This is how it all started... /1

Dear Lipid and Membrane Enthusiasts, There is only one month!! left to register and submit your abstracts for the @embo.org Workshop “Lipid Code to Life”, which will be held from September 7–11, 2026, in Dresden, Germany. Workshop program and registration page: meetings.embo.org/event/26-lip...

That is one way to get funding rates up, I guess. erc.europa.eu/news-events/...

Check out our new release on BioRxiv co-lead by @pm-mueller.bsky.social 👉 rb.gy/lnrizk special🙏 to Severine Kunz #MDC @leventallab.bsky.social @andimicroscopy.bsky.social @ewerslab.bsky.social and Kedar Narayan @NCI CCR VolumeEM Are the days of discovering new cellular structures over?? /1

The world's current business model in a nutshell

This looks extremely interesting conceptually.