André Nadler
@nadlerlab.bsky.social
📤 2300
📥 1786
📝 726
Chemist in a CellBio place. Fan of lipids & membranes
pinned post!
Lipid-CLEM by
@mathilda95.bsky.social
on the Cover of
@natcellbio.nature.com
! Link to article:
www.nature.com/articles/s41...
3 months ago
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Nature Cell Biology
2 days ago
☀️Our July issue's out! Cover:
#lysosome
#metabolite
👉Editorial:
#StemCell
#embryo
models 👉Perspective:
#proteomics
in
#oocytes
& embryo 👉Review:
#ferroptosis
in glial
#tumors
🔬
#mitochondria
#cytoskeleton
#chromatin
#BreastCancer
#PhaseSeparation
#lipids
& more!
www.nature.com/ncb/volumes/...
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This is very cool. I really like it for reasons. 😉
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5 days ago
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Mike Murphy
5 days ago
I have two post doctoral positions available in my lab funded by the Wellcome Trust to develop new chemical biology approaches to studying mitochondria. Would suit those with interest in both mitochondria and chemical biology. Advert below-please forward and repost!
www.cam.ac.uk/jobs/researc...
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Research Associate x 2 (Fixed Term)
The Medical Research Council Mitochondrial Biology Unit (MRC MBU), University of Cambridge, wishes to appoint two post-doctoral Research Associates to join the research group of Prof. Mike Murphy at t...
https://www.cam.ac.uk/jobs/research-associate-x-2-fixed-term-sm50294
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Max-Planck-Gesellschaft
5 days ago
Both articles are back, according to 'Retraction Watch'. Springer Nature un-retracts Planck papers, citing “human error” ->
retractionwatch.com/2026/07/07/s...
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Springer Nature un-retracts Planck papers, citing “human error”
Max Planck Today the Retraction Watch list of Nobelists who have retracted papers bids Verabschiedung to Max Planck. After days of scrutiny, Springer Nature has restored two papers by Planck, who w…
https://retractionwatch.com/2026/07/07/springer-nature-un-retracts-planck-papers-citing-human-error/
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6 days ago
Excited to share our latest paper where we report an MR1-specific nanobody that blocks MR1-mediated T-cell activation. Congrats to Tim Bates, Corinna from David Lewinsohn’s lab, and thanks to
@jburkevic.bsky.social
for HDX-MS support!
@ohsunews.bsky.social
academic.oup.com/jimmunol/art...
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An MR1-specific nanobody capable of blocking MR1T cell activation
Abstract. MR1 is a non-polymorphic, ubiquitously expressed, MHC class I-like antigen-presenting molecule that presents small-molecule metabolites to T cell
https://academic.oup.com/jimmunol/article/215/6/vkag094/8723709?guestAccessKey=2ba63c44-a9bf-4f1c-a513-da0ff1bb4d9c&utm_source=authortollfreelink&utm_campaign=jimmunol&utm_medium=email
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Marieke Oudelaar
8 days ago
We are looking for someone to lead the new Facility for Protein Biochemistry & Biophysics at the MPI of Immunobiology and Epigenetics in Freiburg — please spread the word and apply if you are interested!
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Dazhi Li
8 days ago
Excited to see this study, in collaboration with the De Camilli group
@pdc-lab.bsky.social
, published in its final format! We resolved the structure of VPS13C and found that it adopts a lipid-transfer-incompetent conformation. We also show that CaM binds VPS13s and may help regulate their function.
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Cryo-EM structure of soluble VPS13C suggests its regulation by a conformational switch and by calmodulin
VPS13C, whose dysfunction causes Parkinson’s disease, adopts a lipid-transfer-inactive conformation in the cytoplasm and relies on calmodulin for proper folding and localization to membrane surfaces.
https://www.cell.com/molecular-cell/fulltext/S1097-2765%2826%2900417-X
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NordenLab
12 days ago
#2 Close collaboration with
@rocha-lab.bsky.social
across institutes.
@catfigueiredo.bsky.social
shows that neurogenic progenitors in the developing retina can respond to cell death with an unexpected self-renewing division. I am sure Mauricio has more to say :-).
www.biorxiv.org/content/10.6...
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Apoptosis-induced self-renewal of neurogenic progenitors safeguards retinal development against extensive cell loss
Developing embryos have a striking ability to buffer external and internal perturbations. A key example of this phenomenon across developing systems is successful organ formation even after substantia...
https://www.biorxiv.org/content/10.64898/2026.07.03.735591v1
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NordenLab
12 days ago
We are trying for a hattrick this month and two out of three are out: #1 Great work by Margarida Cruz et al. showing that tissue context in addition to cell intrinsic programs can determine migration mode of neurons. Retinal Bipolar Cells as an example. Check it out!
www.biorxiv.org/content/10.6...
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Tissue lamination state switches neuronal translocation from active to passive in the vertebrate retina
Neuronal migration is essential for establishing functional tissue architecture in the developing central nervous system. While cell-intrinsic mechanisms driving neuronal movement have been identified...
https://www.biorxiv.org/content/10.64898/2026.07.02.736014v1
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Holthuis Lab
13 days ago
📯 Our paper “VPS13C/PARK23 initiates lipid transfer and membrane remodeling for efficient lysosomal repair” out now in Nature Communications
rdcu.be/frKmN
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VPS13C/PARK23 initiates lipid transfer and membrane remodeling for efficient lysosomal repair
Nature Communications - Not all components of the lysosome damage response pathway have been defined. Here, the authors discover that the bridge-like lipid transport protein VPS13C senses lysosomal...
https://rdcu.be/frKmN
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Kedrov Lab @ HHU
12 days ago
Mosbacher Kolloquium
@gbmev.bsky.social
was a splendid event, for the
#lipidtime
crowd and beyond. And now, the Program brochure will be a pass for another highlight, Die Toten Hosen playing tonight in
@duesseldorf.bsky.social
❤️🔥🎸🤘
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Toth-Petroczy lab
13 days ago
I am honored and deeply grateful for the opportunity to continue being part of Dresden’s vibrant and collaborative scientific community as a joint Professor between
@casusscience.bsky.social
and
@biotec-tud.bsky.social
. My dream of doing science for life has come true.
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Ben Engel
13 days ago
Super excited to launch this search for a new endowed professor at the
@biozentrum.unibas.ch
! Join us to build a research cluster in Climate Biophysics! 🌍🌊🌾🔬🧪 This is a unique opportunity to create a community in Basel🇨🇭working together on this timely topic! ⏳🌡️ Questions? Please reach out! 👩🔬👨🔬
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without comment
13 days ago
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This is a great job at a great place.
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13 days ago
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Max-Planck-Gesellschaft
13 days ago
Thank you! We’ve been following this & are currently trying to find out what has prompted Springer Nature to remove the articles. As soon as we know more, we’ll let you know!
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Ich glaube es hackt.
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13 days ago
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Jeremy Baskin
14 days ago
Excited and grateful to have been promoted to Professor. Many thanks to the outstanding students and postdocs in my lab and to my colleagues at Cornell and across the
#chembio
and
#lipidtime
communities for your continued support!
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Laborjournal
14 days ago
„Zur Klarheit angepasst" – so erklärt ThermoFisher das, was Bildforensiker als 127 manipulierte Western-Blot-Bilder in 119 Antikörper-Produkten identifiziert haben. Nächster Akt der Qualitätskrise des kommerziellen Antikörpermarkts: 👉
laborjournal.de/rubric/portrait/biz/biz_26_06_01.php
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André Nadler
15 days ago
Job alert! We’re hiring a Postdoctoral Fellow to develop nanobody-based spatial biology approaches to study TB granulomas. Please help spread the word!
@microbiologysociety.org
@aai.org
@ascbiology.bsky.social
@ohsunews.bsky.social
@embo.org
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In der generellen Umgebung des 16ers abzuhängen und darauf zu hoffen dass der Gegner in Panik gerät ist halt kein guter Plan.
15 days ago
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Christophe 🔬 Leterrier
16 days ago
Why not go 3/3 with Anna Brachet and team from
@iins-bordeaux.bsky.social
. Spectrin rings in dendritic spines, mixed ßII/ßIII-tetramers, MINFLUX images! Also a talk at the Cell Biology of the Neuron GRC:
www.biorxiv.org/content/10.6...
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Christophe 🔬 Leterrier
16 days ago
Next: Ginny Farías' lab shows how neuroligin 1 and 2 are trafficked to the axon initial segment. AIS, spatiotemporal proteomics, endogenous knock-ins! Beautiful pictures and Figures!
dx.doi.org/10.64898/202...
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Christophe 🔬 Leterrier
16 days ago
First up: Gia Voeltz' work on the role of the ER ladder they discovered in growing axons (
doi.org/10.1016/j.de...
) in vesicular transport. Top neuronal cell biology, from light/electron microscopy to identifying the role of organelles contacts via the PRG1 protein:
www.biorxiv.org/content/10.6...
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Alexander Titz
18 days ago
"Springer Nature is nevertheless still selling the empty PDF for $39.95." 😱
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@maxplanck.de
Please look into this. Unbelievable.
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18 days ago
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Great work, good to see it in its final form!
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18 days ago
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James Saenz
19 days ago
We held lab meeting at McDonalds today…they have air conditioning, and lipids
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Carolyn Bertozzi
20 days ago
Jeremy Baskin
@cornellupress.bsky.social
sharing exciting new
#lipidtime
discoveries
@onoinitiative.bsky.social
chem bio symposium
@stanford-chemh.bsky.social
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Fully understand the desire for simple solutions. Also think that solutions are never simple.
21 days ago
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André Nadler
Physics of Life Dresden
21 days ago
🏆 Introducing the inaugural Suzanne Eaton Awards for Physics of Life! We're thrilled to announce the 2026 recipients: L. Mahadevan
@harvard.edu
and Anna Erzberger
@embl.org
. 👨🔬Both scientists will give award lectures on 20. November, more info to follow ➡️Read our announcement here:
tud.link/cjm8t2
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Human Technopole
21 days ago
✨ Meet
@dolliemae.bsky.social
, our new Group Leader in the Molecular Cell Biology Research Centre. 🧬 Her Group will explore how protein mutations reshape cell behaviour and contribute to human disease, focusing on the nuclear envelope. Read more 👉
humantechnopole.it/en/news/intr...
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Introducing Dollie LaJoie - Human Technopole
Dollie LaJoie is a new Research Group Leader at Human Technopole, in the Molecular Cell Biology Research Centre. Her research explores how mutations in proteins can alter cell behaviour and contribute...
https://humantechnopole.it/en/news/introducing-dollie-lajoie/
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Veijo Salo
22 days ago
How does a cell remodel the ER membrane into a lipid droplet? Excited to share our new bioRxiv preprint, where we find that regulated opening of the seipin ring defines a functional ER–lipid droplet interface — and identify SMLR1 as a regulator of this transition.
www.biorxiv.org/content/10.6...
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Markus Deserno
22 days ago
📣 Hear! Hear! 🦋 Behold this Bluetorial on a cool paper written with my PhD student Nathaniel Wesnak 🧪 If you want to dive into the rabbit hole of lipid flop-flop and its description as a stochastic process—here’s your TEASER TRAILER on some flippin’ awesome work:
doi.org/10.1063/5.03...
1/26
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Stochastic process description of lipid flip-flop
Since lipid bilayers are self-assembled macroscopic aggregates, their constituent lipid molecules can spontaneously transition between the two leaflets. This so
https://doi.org/10.1063/5.0326588
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Max-Planck-Gesellschaft
22 days ago
Huge congratulations to Sara Wickström! 🎉Our director
@mpi-muenster.bsky.social
has been awarded the
#KörberPrize
2026. The scientist discovered that genes respond not only to chemical signals but also to the physical properties of their surroundings.
@koerber-stiftung.de
@sarawickstrom.bsky.social
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Anders Sejr Hansen
23 days ago
(1/n) Very excited to share tri-lab collab (Mirny & Zechner) led by Harvey, Henrik & Jack: Q: How do enhancers & promoters interact in space (contact vs. action-at-a-distance) and time (stable vs. transient)? A: Transient E-P contact (~25-42 nm lasting ~10-20 sec):
www.biorxiv.org/content/10.6...
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This is really cool! And I have a problem in mind where the probe (further down the tweetorial 😉) should be really useful...
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23 days ago
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Enabling risky projects through stable long term funding only works if the funding is actually, well, stable.
23 days ago
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André Nadler
Max Planck Institute of Biophysics
26 days ago
1/3: We are proud to share that the recent work by postdocs Karen Palacio-Rodriguez and Sergio Cruz-León, from Gerhard Hummer’s department, was selected as one of the Editors’ Highlights in Nature Communications! 🎉 👏 Open-access paper: 👉
www.nature.com/articles/s41...
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This is just so spectacular. A moment of discovery that most of us can only dream about.
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27 days ago
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J Pardo
27 days ago
New in
@science.org
...since our first discoveries of early tetrapods, they have been thought of as "amphibians" characterized by aquatic larvae. But is this true? For the first time, we report exceptional fossils of stem tetrapod babies that upend this paradigm. 1/n
www.science.org/doi/10.1126/...
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Direct development of stem tetrapods across the fin-to-limb transition
Modern amphibians are characterized by an aquatic larval stage that ends abruptly with a period of widespread tissue remodeling (metamorphosis) upon transition to terrestrial adulthood. A transient la...
https://www.science.org/doi/10.1126/science.aeb7635
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This shouldn't come as a surprise.
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27 days ago
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Max Planck Institute of Molecular Cell Biology and Genetics
27 days ago
Otto Hahn Medal for three
@mpi-cbg.de
researchers: Kristin Böhlig in the group of André Nadler, Alison Kickuth in the group of Jan Brugués
@poldresden.bsky.social
, Giulio Zucal, from MPI-MiS in Leipzig and now mentored by Türkü Özlüm Çelik and
@grill-lab.bsky.social
.
www.mpi-cbg.de/news-outreac...
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Michaela Müller-McNicoll
28 days ago
How can a splicing factor bind to thousands of exons but regulate only a few of them? In our new preprint, we show that SRSF6 resolves this paradox through two distinct binding modes.
@lab-nmr.bsky.social
&
@julianvonehr.bsky.social
. Check it out:
www.researchsquare.com/article/rs-9...
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Pavel Barahtjan
27 days ago
Happy to see our review on glycosphingolipids in cell identity out in
@cp-trendsbiochem.bsky.social
. We discuss how GSLs shape cell identity, from biosynthesis to function, and how tools like bifunctional
#lipids
and MALDI-MSI let us study them to new depths.
tiny.cc/t495101
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Glycosphingolipids in cell identity: Biosynthesis, functions, and emerging tools
Cell fate is shaped by external cues and intrinsic cellular states. While supracellular signals, such as growth factors, provide instructive guidance, emerging evidence highlights the role of cell-aut...
http://tiny.cc/t495101
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Incredibly proud that our lab's Kristin Böhlig is among the Otto Hahn medal awardees. Congratulations to her and all the other honoured doctoral researchers!
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28 days ago
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Max-Planck-Gesellschaft
28 days ago
What a joy it is to celebrate our amazing young scientists today! 🌟🙃 Huge congratulations to our 30 brilliant doctoral researchers honoured w/ the
#OttoHahnMedal
for their extraordinary PhD achievements! 🎉|📷: Our fantastic winners with (a very proud!😊) MPG President
@patrick-cramer.maxplanck.de
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Patrick Cramer
28 days ago
Es sind solche jungen Forscherinnen und Forscher, die mir Hoffnung geben. Herzlichen Glückwunsch an die Preisträgerinnen und Preisträger der Otto-Hahn-Medaille! Ich wünsche den Ausgezeichneten weiterhin viel Erfolg, Neugier und Freude bei ihrer wissenschaftlichen Arbeit.
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Matthew Cobb
30 days ago
Goodness me what bollocks. Of both kinds. Neuro- and AI-bollocks. Tell me how the 30 neurons in the lobster‘s stomach do what they do, lads - dig out the “core algorithm” of that and we might be getting somewhere...
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Jonny Nixon-Abell
29 days ago
Niceeee!!
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