André Nadler
@nadlerlab.bsky.social
📤 2276
📥 1773
📝 692
Chemist in a CellBio place. Fan of lipids & membranes
pinned post!
Lipid-CLEM by
@mathilda95.bsky.social
on the Cover of
@natcellbio.nature.com
! Link to article:
www.nature.com/articles/s41...
about 1 month ago
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André Nadler
Alex Merz 🇺🇸🇨🇦🇺🇦
3 days ago
The University of Washington Department of Microbiology seeks to hire an Assistant Professor, Tenure Track.
apply.interfolio.com/185622
We're interested in mechanistic approaches to study physiology and/or pathogenesis of bacteria and viruses, as well as microbial community interactions.
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Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
https://apply.interfolio.com/185622
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André Nadler
ZMBH
2 days ago
The ZMBH welcomes Dr. James Sáenz
@jamessaenz.bsky.social
as new Professor in Molecular Biology. James previously led a research group at B CUBE - Center for Molecular Bioengineering of Dresden University of Technology.
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André Nadler
Max-Planck-Gesellschaft
2 days ago
An internal compass:
#pigeons
use magnetically responsive immune cells in their livers to sense Earth’s magnetic field, helping them navigate without visual cues like the sun.
www.youtube.com/watch?v=-s8i...
@mpi-animalbehav.bsky.social
@science.org
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Pigeons navigate using magnetic sensors in their livers
YouTube video by Max Planck Institute of Animal Behavior
https://www.youtube.com/watch?v=-s8i2A5lgCI
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André Nadler
Science Magazine
3 days ago
Researchers have identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation.
https://scim.ag/4nTQ3nq
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André Nadler
Reese Richardson
3 days ago
TL;DR: We've identified more than 100 cases of apparent manipulation in Thermo Fisher Scientific's antibody verification data.
@sholtodavid.bsky.social
@johanduchene.bsky.social
reeserichardson.blog/2026/05/28/h...
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How much of Thermo Fisher’s antibody data has been manipulated?
We’ve documented more than 100 instances of apparent data manipulation in Thermo’s catalog
https://reeserichardson.blog/2026/05/28/how-much-of-thermo-fishers-antibody-data-has-been-manipulated/
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reposted by
André Nadler
Journal of Cell Biology
3 days ago
Any1 is a
#phospholipid
scramblase involved in
#endosome
biogenesis. From Jieqiong Gao, Christian Ungermann and colleagues:
rupress.org/jcb/article/...
📕 Part of
#Lysosomes
2026:
rupress.org/jcb/collecti...
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André Nadler
Jeremy Baskin
4 days ago
Hallo, Dresden, you hotbed of
#lipidtime
research! Thanks to
@nadlerlab.bsky.social
for hosting me at
@mpi-cbg.de
yesterday — and looking forward to giving the plenary talk at the European Symposia of Bioorganic Chemistry meeting later today!
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André Nadler
Journal of Cell Science
5 days ago
Lazar Ivanović, Wanda Kukulski and colleagues dissect the molecular basis of tricalbin-mediated membrane contact site organisation in cells. Highlight:
journals.biologists.com/jcs/article/...
Article:
journals.biologists.com/jcs/article/...
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André Nadler
Mike Feigin 🥯
9 days ago
🚨 New preprint from the Feigin Lab! 🚨
www.biorxiv.org/content/10.6...
Opioids have profound effects on the pancreatic cancer microenvironment! An FDA-approved opioid antagonist that doesn't cross the blood brain barrier decreases tumor aggressiveness in a mouse model of pancreatic cancer!
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https://www.biorxiv.org/content/10.64898/2026.05.20.726559v1
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André Nadler
Alex Merz 🇺🇸🇨🇦🇺🇦
10 days ago
Lovely new preprint on how membrane microdomain formation controls endosomal protein sorting, from Kam Shan Hu, Barth Grant,
@barrlab.bsky.social
and colleagues:
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André Nadler
Clausen Lab
10 days ago
Open Postdoc Position - Giant E3 ligases: mysterious mechanisms & non‑protein substrates. Interested? Join us to uncover how these molecular giants tag lipids, RNAs, sugars beyond proteins, on organelles and pathogens, to defend the cell. Details & Application here
www.imp.ac.at/career/open-...
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André Nadler
Caroline Bartman
11 days ago
🚨first Bartman lab preprint! it's an LC-MS method to measure "total Coenzyme A" (sum of all acyl-CoAs). this will let us study coA synthesis flux using heavy-isotope tracing! huge congrats to first author Amelia Taylor and star coauthor
@mzspectrum.bsky.social
!
www.biorxiv.org/content/10.6...
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https://www.biorxiv.org/content/10.64898/2026.05.19.726225v1
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Jonathan Kaufman
13 days ago
It's finally out! Molecular architecture of mammalian AP3:ARF1 carriers - a mechanism for lysosomal membrane protein trafficking - from a combination of
#biochemistry
,
#cryoET
and
#cellbiology
📝 Paper:
www.science.org/doi/10.1126/...
🧵 Thread: subsequently
#teamtomo
#membranetrafficking
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André Nadler
Alexey Amunts
18 days ago
Delighted to welcome our new PI, Daxiao Sun who is starting her lab at SMART after a postdoc with
@hymanlab.bsky.social
@mpi-cbg.de
and Alf Honigmann
@biotec-tud.bsky.social
Daxiao’s group will investigate how biomolecular condensates regulate cell junctions and tissue morphogenesis. Welcome!
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André Nadler
Sophie G Martin
19 days ago
How do cells communicate? They use Sms1 ! 🙂 More seriously, Sms1 is the scaffold of the pheromone-MAPK signalling cascade in fission yeast, which
@borissieber.bsky.social
et al discovered. Have a look at the paper 👇
@biology-unige.bsky.social
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reposted by
André Nadler
Ruben Ragg
19 days ago
S. cerevisiae is emerging as a whole-cell factory for producing pharmaceutically relevant amines. This Review by the Francesco Mutti lab in
#ChemBioChem
(
@chemistryeurope.bsky.social
) maps strain-engineering strategies that could make amine biocatalysis more scalable.
doi.org/10.1002/cbic...
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This is very, very cool. Congratulations!
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19 days ago
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André Nadler
DGZ.bsky.social
20 days ago
On June 30 at noon, the next
#DGZ
Focus Workshop on
#MembraneOrganization
&
#ContactSites
will take place, organized by Sabrine Buettner & Katja Zieske. Speakers: André Nadler
@nadlerlab.bsky.social
, Suzan Kors, Zexi Xu and Emma Fenech. Join us!
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André Nadler
Philip Ball
21 days ago
i.e. it is just fairly good mimicry of consciousness, parasitic on ours. And this seems so obvious. Yet smart people keep falling for it. Is this really so hard?
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reposted by
André Nadler
Ewerslab
26 days ago
New paper out! Left-handed DNA cannot bind to natural, right-handed DNA. This leads to lower background if it is used as a probe in DNA-PAINT. Using Fluorigenic DNA-PAINT with left-handed DNA allows for low background, fast 3D DNA-PAINT! Congrats, Bas! skeetorial: 1/x
pubs.acs.org/doi/full/10....
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Accelerated Left-Handed DNA-PAINT Using Fluorogenic Probes
Single-molecule localization microscopy (SMLM) techniques offer nanometer-scale resolution by stochastically localizing individual fluorescent molecules. Among these, DNA-mediated point accumulation f...
https://pubs.acs.org/doi/full/10.1021/acs.nanolett.5c05973
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André Nadler
Derek Lowe
27 days ago
The helium shortage is now unavoidable. Another wonderful follow-on to the Iran War, and if you think helium doesn’t matter much, think again:
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Helium and the Strait of Hormuz
https://www.science.org/content/blog-post/helium-and-strait-hormuz
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reposted by
André Nadler
Journal of Cell Biology
27 days ago
Building bridges: BLTP2 forms ER-plasma membrane contact sites.
@flofroehlich.bsky.social
discusses two recent studies from Dziurdzik et al. & Dai et al. (
doi.org/10.1083/jcb....
&
doi.org/10.1083/jcb....
):
rupress.org/jcb/article-...
#ER_Literature
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reposted by
André Nadler
Max Planck Institute for Chemical Ecology
27 days ago
Congratulations to
@hellmichgroup.bsky.social
! The Max Planck Society awarded her a Max Planck Fellowship. We are happy to have her as a Max Planck Fellow and look forward to intensifying our collaboration with her.
www.ice.mpg.de/556225/ute-h...
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Ute Hellmich becomes Max Planck Fellow - New research group on Signaling Dynamics
https://www.ice.mpg.de/556225/ute-hellmich-becomes-max-planck-fellow
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André Nadler
Tera Levin
29 days ago
Bacterial immune proteins have repeatedly evolved to become parts of eukaryotic immunity. But how? Our new preprint uncovers a recent horizontal transfer event & shows how eukaryotes co-opted a toxic bacterial immune protein 🦠🧪🧵 1/
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I really like this.
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28 days ago
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André Nadler
Nature Cell Biology
30 days ago
☕Paquola et al. present a technique named lipid-trap mass spectrometry (LTMS) to study lipid–protein interactions directly captured from mammalian cells.
bit.ly/4tEPW10
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Lipid-trap mass spectrometry identifies lipid–protein interactions in cells - Nature Cell Biology
Paquola et al. present a technique named lipid-trap mass spectrometry (LTMS) to study lipid–protein interactions directly captured from mammalian cells.
https://bit.ly/4tEPW10
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André Nadler
Itay Budin
30 days ago
What membrane properties do cells maintain through regulation of lipid metabolism? In a new paper, we identify intrinsic curvature stress as one such parameter and show how different (eukaryotic) cell types employ different lipids to do that
www.cell.com/cell-reports...
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Active regulation of intrinsic curvature by eukaryotic phospholipid metabolism
Cells maintain membrane function by actively balancing the molecular shape of their lipids. Milshteyn et al. find that, when subjected to high hydrostatic pressure, yeast and human cells, but not bact...
https://www.cell.com/cell-reports-physical-science/fulltext/S2666-3864%2826%2900183-9
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André Nadler
Michalis Averof
about 1 month ago
These images show live embryos of animals (jellyfish, crustacean, worm, sea urchin, sea squirt, beetle) and one of animals closest single-celled relatives. They were captured taking advantage of fluorescent proteins localised on the outer membrane of cells, allowing us to observe cell outlines. 1/9
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André Nadler
Holthuis Lab
about 1 month ago
📯Proud to share a preprint of a joint paper with Michael Timme and
@melolab.bsky.social
on how ceramides disrupt hexokinase binding to VDACs and modulate channel tilting. Our CG-MD simulations reveal a potential mechanism by which ceramides may induce apoptotic cell death📯
bsky.app/profile/bior...
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That is very good news. And knowing that the
@erc.europa.eu
takes feedback from the community is encouraging.
add a skeleton here at some point
about 1 month ago
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5
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reposted by
André Nadler
Max Planck Institute of Molecular Cell Biology and Genetics
about 1 month ago
Anthony Hyman
@embl.org
&
@mpi-cbg.de
@hymanlab.bsky.social
& Clifford Brangwynne
@princetonupress.bsky.social
&
@hhmi-science.bsky.social
receive their 2023 Breakthrough Prize at the Awards Ceremony in Santa Monica,LA, April 18, by Eileen Gu &
@mrgatoasdf.bsky.social
!
www.mpi-cbg.de/news-outreac...
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Breakthrough Prize Award Ceremony
Antony Hyman and Clifford Brangwynne receive their 2023 Breakthrough Prize
https://www.mpi-cbg.de/news-outreach/news-media/article/breakthrough-prize-award-ceremony
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André Nadler
José Delgado, Ph.D.
about 1 month ago
🚨New Pernas Lab Preprint is live!! 🚨 Here we show that mitochondria shed "new organelles" that engulf lysosomes and become acidified compartments during intracellular infection! Video below shows SPOTs acquiring a lyso (C: matrix, Y: OMM, R: Lyso) 🔬. 🔗:
www.biorxiv.org/content/10.6...
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André Nadler
Journal of Cell Biology
about 1 month ago
@flofroehlich.bsky.social
discusses two recent studies from Dziurdzik et al. & Dai et al.(
doi.org/10.1083/jcb....
&
doi.org/10.1083/jcb....
) describing a plasma membrane ER contact site formed by BLTP2 and its adaptor proteins.
rupress.org/jcb/article-...
#ER_literature
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Fantastic work. What a
#lipidtime
to work in.
add a skeleton here at some point
about 1 month ago
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Congrats!!! Amazing news.
add a skeleton here at some point
about 1 month ago
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Thought-provoking
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about 1 month ago
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André Nadler
Claudia Matthaeus
about 1 month ago
Interested in caveole and/or lipid metabolism? We have two master thesis projects available in the lab
@unipotsdam.bsky.social
starting September or October. For more details 👇
www.matthaeus-lab.de/post/04-2026...
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04/2026 Master thesis projects available
We have two exciting master thesis projects available in the lab. Please see the announcements below. Start date is flexible, but earliest September or October 2026. If you are interested, please send...
https://www.matthaeus-lab.de/post/04-2026-master-thesis-projects-available
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André Nadler
Yamuna Krishnan
about 1 month ago
Pro-tip: Before I submit my proposal, I read it again, but after 2 glasses of wine on an empty stomach. Places where it isn't totally clear to you in that state, it not going to be clear to the reviewer. Edit that bit.
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André Nadler
Campàs Lab
about 1 month ago
Interested in Physics of Life? Curious about what are the scientific questions we study at
@poldresden.bsky.social
? You can learn that in less than 3 min 🤩👇 Thanks to Avanga Film production for the great video 🎬
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André Nadler
Katharina Geißler
about 1 month ago
Out now in Nature Communications! We show that Dictyostelium vaults associate with ER and NE membranes in situ and encapsulate ribosomes with defined orientations, shining new light on their cellular function!
#TeamTomo
#TeamMassSpec
#ProtistsOnSky
www.nature.com/articles/s41...
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André Nadler
Fran Bottanelli
about 1 month ago
Exciting to see this out in its final form! Wonderful work led by
@probablycarmen.bsky.social
. Want to know why protrusions are better at initiating immune signaling in
#Tcells
? Look no further. Link to Carmen’s 🧵 on the preprint
bsky.app/profile/prob...
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André Nadler
Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
about 1 month ago
Our
#UExM
efforts with
@gautamdey.bsky.social
&
@moorefound.bsky.social
featured in
@nature.com
this month. Beyond the
#science
, every image is a thing of beauty. I think a world-tour exhibition has to happen at one point.
#Expansion
#Microscopy
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reposted by
André Nadler
Max Planck Institute of Molecular Cell Biology and Genetics
about 1 month ago
On April 15th,
@leopoldina.org
welcomed its new members of Class II Life Sciences. Meritxell Huch
@merihuchlab.bsky.social
, director
@mpi-cbg.de
, is among them and received their membership certificate together with fifteen other new members. Congratulations! 🎉 Photo: Marlene Gawrisch | Leopoldina
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Lipid-CLEM by
@mathilda95.bsky.social
on the Cover of
@natcellbio.nature.com
! Link to article:
www.nature.com/articles/s41...
about 1 month ago
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reposted by
André Nadler
Paul Markus Müller 🏳️🌈
about 1 month ago
Original image from 2011 of what I just had seen under the microscope when I ran into
@oliverrocks.bsky.social
’s office to show him. Turned out he’d observed this too, had no idea what it was either, but was just as stunned and curious as I was. This is how it all started... /1
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André Nadler
Coskun Lipid Cellar @ ZML Dresden
about 1 month ago
Dear Lipid and Membrane Enthusiasts, There is only one month!! left to register and submit your abstracts for the
@embo.org
Workshop “Lipid Code to Life”, which will be held from September 7–11, 2026, in Dresden, Germany. Workshop program and registration page:
meetings.embo.org/event/26-lip...
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Lipid Code to Life
Modern lipid biology has evolved far beyond the traditional view of lipids as simple building blocks or energy substrates. Lipids are now recognised as dynamic regulators of biological structures and…
https://meetings.embo.org/event/26-lipid-code
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That is one way to get funding rates up, I guess.
erc.europa.eu/news-events/...
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Applying for an ERC grant in the 2027 competitions: what you need to know
The ERC plans to launch the grant competitions under its 2027 Work Programme between July 2026 and June 2027, with the calls for proposals introducing several changes to the eligibility rules for appl...
https://erc.europa.eu/news-events/news/applying-erc-grant-2027-competitions-what-you-need-know
about 1 month ago
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reposted by
André Nadler
Oliver Rocks
about 2 months ago
Check out our new release on BioRxiv co-lead by
@pm-mueller.bsky.social
👉
rb.gy/lnrizk
special🙏 to Severine Kunz
#MDC
@leventallab.bsky.social
@andimicroscopy.bsky.social
@ewerslab.bsky.social
and Kedar Narayan @NCI CCR VolumeEM Are the days of discovering new cellular structures over?? /1
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The world's current business model in a nutshell
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about 2 months ago
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This looks extremely interesting conceptually.
add a skeleton here at some point
about 2 months ago
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