😍😍😍. Congrats folks.!!

My recent postdoctoral work is out today in @nature.com! We found that physical confinement makes melanoma cells more invasive and drug tolerant. Thanks to all who made this work possible @whitefishlab.bsky.social @mskcancercenter.bsky.social #NIH #NCI www.nature.com/articles/s41...

Finally out in Nature Chem Bio: SNAP-tag2 for faster and brighter protein labeling www.nature.com/articles/s41... Thank you Steffi and Veselin.

The german research foundation DFG will fund the new graduate school for "Biomolecular Condensates: from physics to biological function" here in Dresden This new graduate school is part of 18 new graduate schools funded by the DFG in germany!

Hugely significant finding for contact site research - can’t wait to read properly! www.nature.com/articles/s41...

Do you see any underlying driver/correlator for these numbers? Number of canceled NIH grants by institution: 1 Columbia U 163 2 Johns Hopkins 12 3 Emory 6 4 U. Michigan 5 5 U. Minnesota 5 6 U Miami Med Sch. 4 7 UCSF 4 8 U Chicago 3 Source: taggs.hhs.gov/Content/Data...

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes! Annexin A11 tethers RNP granules to membranes in a Ca2+ dependent manner. @abelljonny.bsky.social, @michael-e-ward.bsky.social, et al. www.nature.com/articles/s41...

😊 Very happy to see this out! A real group effort from the Hyslop lab (@thecimr.bsky.social) including brilliant collaborations with @knowleslab.bsky.social, Vendruscolo lab, @michael-e-ward.bsky.social lab, @deriverylab.bsky.social lab, @profmarciniak.bsky.social lab 🎉🎉🎉

Great interview with the always inspiring JLS - absolutely shaped so much about mine and so many others careers…

*Please repost* @sjgreenwood.bsky.social and I just launched a new personalized feed (*please pin*) that we hope will become a "must use" for #academicsky. The feed shows posts about papers filtered by *your* follower network. It's become my default Bluesky experience bsky.app/profile/pape...

I have to say…unlike the Twitter heyday (and even still X now), I just don’t get good science content on Bluesky. In particular, I can’t find people posting new cell biology/microscopy/neurobiology papers at anywhere near the same frequency. My feed on Twitter used to be 90%+ of this content…

Such a cool story! Congrats guys…

We are experiencing an assault on science unparalleled by anything I’ve seen in my life. It’s not one issue or another anymore, the entire institution is under attack by the most powerful individuals in the country. This Friday, where will you be? standupforscience2025.org

This is such a great programme and a big thanks to Venkat Pisupati who has done all the heavy listing from our group to make this possible.

After a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool. www.nature.com/articles/s41...

So much happening in the segmentation space for bioimage analysis. These two papers that were published online today really stood out to me as noteworthy (a thread).

Hello! Although we are still in the other place, this will become our main social media feed. We're part of the University of Cambridge Clinical School Cell biology, molecular mechanisms of human disease

Our first preprint list for 2025 is focussed on research using microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see on our list. focalplane.biologists.com/2025/01/10/m...

Fantastic work by my Biohub colleague Manu Leonetti and his amazing team published in #Cell! 🧪 Human cell #proteomics subcellular landscape and its dynamic remodeling using #organelle IP. Paper here www.cell.com/cell/fulltex... Explore the date organelles.czbiohub.org Congratulations to the team

😮‍💨😮‍💨😮‍💨 nothing beats isotropy 🤷

🎉 If you’re at #cellbio24 then make sure to join us tomorrow for a bloody great lineup of talks on the ER! Anddddd if you’re heading to the MBL party tonight then come and find me for some painkillers 😅…

🎉 I'm starting my own lab at EMBL-EBI (Cambridge, UK; June 2025) 🎉 We will focus on identifying and characterizing chemical hazards to humans and ecosystems using computational biology methods. I am beginning the search for two postdocs now - stay tuned for more details! ewaldlab.org

Very cool!

Yo yo yo….. #Cellbio2024 friends. Landing today in San Diego and leave evening of 18th. Shoot me a WhatsApp or email if you want to catch up 😊😊. Looking forward to seeing you!!

I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏 www.nytimes.com/2024/12/09/h...

Hands down one of the best experiences you can have. Working with incredible scientists and having an amazing time! I could not recommend anything more!!! Please help circulate!

Love #lipids and #membranes??? Then you cannot miss these seminars tomorrow with two amazing rising ⭐️ ⭐️ @abelljonny.bsky.social @ibudin.bsky.social

Reminder that if disordered proteins are your thing, this starter pack exists (and I try to update it as best I can as new folks reach out/I see them!) 🍝 go.bsky.app/J23B51L

Should be fun and hope to see some of you there 😬!

My turn to create a starter pack for scientists using live imaging in their research! Of course, I’ve likely missed many—please let me know who else I should include. Thanks! go.bsky.app/KYYr7xc #liveimaging #livevellimaging #microscopy

I meant to do this last week but hi everyone, I'm Alex. I love all things neuronal and spend most of my time trying to image motor proteins and organelle movement in the axon.

detection of membrane contact dynamics and Ca2+ signals w/ nice acronym- PRINCESS (PRobe for INterorganelle Ca2+-Exchange Sites based on SplitFAST), a class of reporters to simultaneously detect MCSs and measure the associated Ca2+ dynamics using a single biosensor www.nature.com/articles/s41...

Hullooooo Cell Biology friends. If you're heading to #CellBio2024 in (hopefully!) sunny San Diego this year, then come and check out our session on 'ER structure and function across cell types' Room28C- Dec18th 09:00am! See you there! **Please RT** 🥳

go.bsky.app/HU7e761 @mattoolab.bsky.social done !!!!

A school of starter packs….

Welcome all (new) followers! Besides our work on probes & biosensors I'd like to share what I know about #Rstats and #DataViz. So I composed a book on data visualization with R & ggplot2 (it's work in progress). Target audience = wet lab scientists. Link: joachimgoedhart.github.io/DataViz-prot...

nice to see so many people coming over from the other side...welcome! 👋 I'm Jo, a group leader @ UKDRI @ Imperial studying all things synapses in neurodegeneration. Tweet about synapses, multi-'omics, human 🧠 tissue, 🔬imaging and EDI #WomenInSTEM Anyone have a synapse starter pack? #neuroskyence

A starter pack! Some of my favorite women in neuroscience (sorry if I forgot you, I will add!) go.bsky.app/SCFmKoC

Have a protein for which you want to predict disordered regions? Why not try metapredict V3? www.biorxiv.org/content/10.1... State-of-the-art accuracy, proteome-scale predictions in seconds, command-line tool, webserver, colab notebook, Docker container, etc. Check it out here: metapredict.net

First Microscopy Post on here 🥳🥳!! Single molecule protein dynamics at ER-Mito contact sites😬...here we are looking at Individual VAPB molecules, an important contact site tethering molecule. From our recent paper www.nature.com/articles/s41...

Happy to announce that mine and Chris’s paper from our time in thr JLS lab is fianlly out. It you Like membrane contact sites and/or single molecule imaging, this one might be for you 😊 www.nature.com/articles/s41... a

Want to explore dynamic cell & tissue responses to damage? Apply for our fully-funded #PhDposition @BristolBiochem unravelling molecular mechanisms of #tissuerepair & #inflammation using #liveimaging #omics #cellbiology and #Drosophila for 2024. Please share! Apply here: shorturl.at/fLY26

#FIRSTPOST🍻🍻🍻Well folks…some great news to share. Incredibly happy to announce that I’ll be starting my group @TheCIMR in Feb2024 with funding from a @wellcometrust CDA. A massive thanks to CIMR and my various mentors @ProfKHarvey, @JLS_Lab, Craig Blackstone and Peter St George Hyslop!