Stalder, Pereira, @dgershlick.bsky.social et al. @thecimr.bsky.social uncover new regulators of #Golgi-to-plasma membrane transport, showing that a PTPN23-dependent #ESCRT pathway is essential for secretion of membrane & soluble cargoes, including hormones & antibodies. rupress.org/jcb/article/...

Well done to CIMR PhD student Lewis & the rest of the team!

Ever wondered what microscopes can reveal? 🔬 Visit us at the Cambridge Festival (@cambridgefestival.bsky.social) to find out more! 📆 21/03 ⏰ 11am-4pm 📍Cambridge Academy for Science and Technology #CamFest

Come and find us on the second floor of the Cambridge Academy for Science and Technology, this Saturday 21 March from 11am-4pm and get hands-on with cancer research in Cambridge as part of the @cambridgefestival.bsky.social! 🥽 🦠 🧬 Find out more ➡️ zurl.co/GC3pX

Looking forward to @cambridgefestival.bsky.social open day at the @cambridgebiocampus.bsky.social next Saturday. Come and join us at Cambridge Academy for Science and Technology for lots of family-friendly science!

Delighted to announce that @antonvenhuizen.bsky.social has received a Marie Skłodowska-Curie Actions Postdoctoral Fellowship Award, working with @melissa-gammons1.bsky.social to further understanding of the rare genetic disease Robinow Syndrome www.cimr.cam.ac.uk/news/cimr-re...

The @thecimr.bsky.social and MRC Mitochondrial Biology Unit are celebrating "Rare Research Day" TODAY! By creating factsheets on how their work contributes to greater understanding and potential treatments. #RareDiseaseDay #ShareYourColours #RareDiseaseDay2026 #UniversityofCambridge

Celebrating the efforts that many scientists put into understanding and curing #rarediseases +++investment needed!! 11 years for me working on #CF #IPF, now #BHD #FPF @lifearc.bsky.social @profmarciniak.bsky.social @jennydickens41.bsky.social @thecimr.bsky.social @universitypress.cambridge.org

7 years of working on various rare diseases and emphasising on its impact every single day! Here is the outline of our current research of rare respiratory disease in Dickens Lab at Cambridge #RareDiseaseDay #28thFebruary #DickensLab_CIMR_UniversityofCambridge

School pupils Noor and Zarah spent a few days in our lab at @thecimr.bsky.social over half-term as part of the ISAC/M programme. Their mini projects had them studying cellular senescence & antitrypsin polymerisation respectively Their talks at @stcatharines.bsky.social today did us proud 🥹🔬🧬

We're having a great half term week with this year's lovely group of year 12 work experience students. Looking forward to a day @stcatharines.bsky.social tomorrow!

Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate | Science www.science.org/doi/10.1126/...

We have a fantastic opportunity for a PhD studentship in collaboration with @jesuscollegecam.bsky.social and Cambridge Children’s Research Institute, part of the new Cambridge Children’s Hospital. Closing date 20th Feb; all the details here: www.cimr.cam.ac.uk/postgraduate...

Join #CamRARE in Cambridge (27 Feb) for #RareDiseaseDay Through powerful lived-experience stories & a multidisciplinary panel, we’ll explore what it means to live with a rare condition & how systems can better respond throughout a lifetime. Tickets: camrarerarediseaseday2026.eventbrite.co.uk

In a collaboration with @stevethechemist.bsky.social at Yusuf Hamied Dept of Chemistry, Dr Sam Daly from the @dgershlick.bsky.social lab has developed a new 3D microscopy technique allows researchers to visualise individual molecules inside living cells www.cimr.cam.ac.uk/news/new-3d-...

Congratulations to PhD student Ellie Fox who has been awarded the EMBO Journal Poster Prize, at the UK Membrane Trafficking Meeting 2025. Ellie's PhD is a collaborative project with @dgershlick.bsky.social lab, Daniel Fazakerley @ims-mrl.bsky.social & Morag Rose Hunter @astra-zeneca.bsky.social

Well done to @jenniferepalmer.bsky.social who's been awarded the @ukdri.ac.uk PhD prize, given to researchers whose work has significantly advanced the understanding, diagnosis, treatment, or prevention of dementia and neurodegenerative diseases. 👏👏👏

We have some very crafty staff here at CIMR! Thanks to the amazing reception team for the beautiful hand-made decorations and to the labs who contributed science themed wreaths to brighten up our building

Just a couple of weeks left to apply for our taught Masters in the Molecular Mechanisms of Human Disease. All details here: www.cimr.cam.ac.uk/postgraduate... Apply by the funding deadline, 2nd December

The Cambridge Biomedical Campus Open Mic returns! With a fully stocked bar and food on sale, whether you’re performing or just soaking up the atmosphere, everyone is welcome – you don’t need to work at the Biomedical Campus to join in! Find out more: cambridge-biomedical.com/event/open-m...

Our mission is to determine the molecular mechanisms of disease in order to advance human health. Want to join our vibrant and diverse research institute as a funded PhD or taught MPhil student? Apply by the 2nd December 2025. More information here: www.cimr.cam.ac.uk/postgraduate...

Great win for @darwincollegecam.bsky.social in last night's University Challenge - featuring CIMR PhD student Lewis Strachan. Well done team!

Fantastic news! Well done Lily

Spread the word! Outstanding UK students can experience life at Catz @isaacphysics.org STEM SMART: apply by 31 Oct undergraduate.study.... @thecimr.bsky.social Inspiring Scientists: apply by 21 Nov cimr.cam.ac.uk/inspi... @cam.ac.uk Bangla Soc Access Day: apply by 15 Dec forms.gle/KReLakbpAS...

The beginning of a new era. Behold the Dickens lab @thecimr.bsky.social - small but perfectly formed. Excited for what is to come! Thanks @profmarciniak.bsky.social for letting me squat until now…

As always, the Big Biology Day at Hills Rd Sixth Form was an absolute blast! A great morning with @alzheimersresearchuk.org and a great afternoon with @thecimr.bsky.social

The #RAREsummit25 agenda is live! Packed with diverse voices, patient-driven insights & bold innovation. www.camraredisease.org/raresummit25... Grab your ticket to join us on 6 Nov to be part of the conversation & on't forget to book your dinner spot! What are you most looking forward to?

We've just welcomed this year's cohort of MPhil students studying the Molecular Mechanism of Human Disease so it's time to start preparing for next year! Applications are now open - details and link to apply here: www.cimr.cam.ac.uk/masters-mole...

Only two more days to go!! This Saturday from 10am to 4pm at Hills Road Sixth Form @thecimr.bsky.social will be joining Big Biology Day. Come along and bring your #family to join in lots of #fun #science activities.

Applications now open for our work experience programme for year 12 students, run with @mrc-mbu.bsky.social & @stcatharines.bsky.social We give students a valuable insight into life as a research scientist and student in Cambridge. Details & application link here: www.cimr.cam.ac.uk/inspiring-sc...

Great to welcome our second cohort of students to our Masters in Molecular Mechanism of Human Disease today. Have a good year everyone!

We're looking forward to the Big Biology Day at Hills Road Sixth Form on Saturday 11th October - who's coming?

*job alert** Wanted - 2 enthusiastic postdocs to join me @thecimr.bsky.social and Emma Rawlins @labrawlins.bsky.social to build complex models and use -omic approaches to understand mechanisms in human lung disease in collaboration with GSK. Contact us for more info! www.jobs.cam.ac.uk/job/52936/

Great new paper highlighting @jenniferepalmer.bsky.social 's PhD work: www.cimr.cam.ac.uk/research-adv...

New JCS snapshot - Cytotoxic T lymphocytes adapt to the loss of Cdc42 @adamrochussen.bsky.social presents the key findings from their recent JCS paper with Claire Ma and Gillian Griffiths @griffithslab.bsky.social. journals.biologists.com/jcs/article/...

🧠 Cambridge scientist reveals how autophagy clears toxic proteins in neurodegeneration in Genomic Press Interview. Dr. Rubinsztein's breakthrough: cellular cleanup fights Huntington's, Parkinson's & Alzheimer's! 134k+ citations 🔬✨ 📄🆓 DOI: doi.org/10.61373/bm0... Source: genomicpress.kglmeridian.com

. @adamrochussen.bsky.social, Claire Ma & Gillian Griffiths @griffithslab.bsky.social find that deletion of Cdc42 in primary T cells triggers transcriptional adaptation, leading to enhanced T cell function. journals.biologists.com/jcs/article/... Article: journals.biologists.com/jcs/article/...

Sometimes, knocking out a gene isn't a good way to figure out the function of that gene ... In our new @jcellsci.bsky.social paper, we report potent transcriptional adaptation by cytotoxic T lymphocytes (CTLs) in response to CRISPR/Cas9-mediated deletion of the important polarity protein CDC42 🧵⬇️

Great news² 🥳 Clinical PhD student Niki Veale has just passed his PhD viva so will become Dr Dr Veale (Dr² Veale) We’ve also learned that he’s secured a Clinical Lectureship so will return to the lab as a post-doc (or is that post-doc-doc?) @thecimr.bsky.social @veale-n.bsky.social

Congratulations Adam!

New preprint alert! Endogenous gene editing of alveolar organoids to investigate mechanisms of epithelial dysfunction in familial ILD. Kudos first author @eimearrutherford.bsky.social and thanks @thecimr.bsky.social @labrawlins.bsky.social @profmarciniak.bsky.social www.biorxiv.org/content/10.1...

Could climate change bring new diseases to the UK? Prof Michael Weekes spoke to @the-independent.com recently www.independent.co.uk/climate-chan...

We had a such a great week with this lovely group of students on @gurdoninstitute.bsky.social ASTP programme- they did some fantastic presentations on Friday! Well done to all of them 👋👋👋

Such a rewarding experience to host these ASTP students and guide them through an exciting weak of science discovery @thecimr.bsky.social I’m glad I could convey the importance of sterile conditions in cell culture 😂😂

We're loving hosting students for the @gurdoninstitute.bsky.social ASTP programme, along with @mrc-mbu.bsky.social . As ever, so impressed with the next generation of scientists!

Rounding up today's flurry of new papers is this one from the Salje lab www.cimr.cam.ac.uk/research-adv...

And another one from the very busy @deanelab.bsky.social - this time PhD work from Alex Nicholson www.cimr.cam.ac.uk/research-adv...

New in from @deanelab.bsky.social www.nature.com/articles/s41...

New insights from the Salje lab into the little-known but common Scrub typhus - a vector-borne human disease caused by the bacterium Orientia tsutsugmushi and spread by mites: www.cimr.cam.ac.uk/research-adv...

Great new paper from the Rubinsztein lab www.cimr.cam.ac.uk/research-adv...