Excited about our pre-print on AXIN1 mutations in HCC!
We found that AXIN1 mutations drive low but physiologically relevant levels of Wnt/β-catenin signaling, while being permissive to YAP/TAZ activation. This helps explain why mutations in AXIN1 and β-catenin are linked to distinct HCC subtypes.
add a skeleton here at some point
11 months ago